Comparison of Histologic Changes According to Treatment Method in Experimentally Perforated Rabbit Eyes

Perforation of the choroid and retina during strabismus surgery is fairly common and optimal management of global perforation is contoversial. The authorsinvestigated the histological changes of the rabbit eyes to compare the treatment effects of diode laser photocoagulation, cryotreatment, and nontreatment in experimentally perforated rabbit eyes.We perforated the globe of 6 pigmented rabbits (12 eyes)and treated four eyes with diode laser and four with cryotherapy and did not treat the remaining four.Proliferation of stromal cells and chorioretinal adhesion were seen in untreated eyes. The cryotherapy eyes revealed retinal destruction and pigment-laden cells in all retinal layers.The eyes treated by diode laser showed firm chorioretinal adhesion and relatively well preserved inner layers of retina.We concluded that directed diode laser photocoagulation was a safe and effective method of retinopexy to prevent the retinal detachment after globe perforation durng strabismus surgery.

Refractive States of 3~4 Year Olds that Underwent Cryotherapy in ROP

The previous researches proved that the incidence of myopia in cryotreated retinopathy of prematurity[ROP]eyes is higher than that of non-treated ROP eyes. The authors compared refractive states, anterior-posterior axial length and other contributing factors of treated eyes with those of nontreated eyes at the same age group between 3~4 years old. In the cases of cryotreated group, the mean refractive error was -3.48 +/-4.02D. Among 42 treated eyes, 30 eyes became myopic[71.4%]. The mean axial length was 22.46 +/-1.43mm. The mean length of posterior segment was 15.53 +/-1.33mm. In contrast, the mean refractive error was 1.09 +/-1.04D in non-cryotreated group. Three eyes among 42 untreated eyes developed myopia [7.1%]. The mean axial length was 21.02 +/-1.17 mm. The mean length of posterior segment is 14.09 +/-0.97mm. We concluded that myopia could be developed in cryotreated ROP eyes by the elongation of eyeball, specifically of posterior segment.