Corrección de ojeras y del surco nasoyugal con Nanofat / Correction of dark circles and nasojugal sulcus with Nanofat

Introducción: El envejecimiento periorbitario se considera un proceso complejo y multifactorial que se relaciona con procesos intrínsecos y extrínsecos tales como los cambios degenerativos en la piel, la aparición de líneas finas, la pérdida de volumen, el descenso de tejidos, la piel flácida y el exceso de depósito de grasa. Objetivo: Evaluar los resultados de la corrección de las ojeras y del surco nasoyugal con Nanofat. Métodos: Se realizó un estudio longitudinal prospectivo en el Servicio de Cirugía Plástica y Caumatología del Hospital Clínico Quirúrgico "Hermanos Ameijeiras" desde agosto de 2019 a mayo de 2021. La muestra la constituyeron 37 pacientes. Los datos se resumieron en frecuencias absolutas y relativas. Resultados: La edad promedio fue 47,2 ± 10,7 años. El 89,2 por ciento de los pacientes eran mujeres. La media del tejido emulsionado infiltrado por cada lado fue de 1,40 ± 0,4 ml, con un volumen mínimo de 1 ml y un máximo de 2 ml. En el 83,8 por ciento de los casos se constató una disminución del surco nasoyugal y en el 16,2 por ciento se evidenció una gran mejoría. En el 100 por ciento de los pacientes hubo avance de la hiperpigmentación y mejoría de la calidad de la piel. Dentro de las complicaciones solo un paciente (2,7 por ciento) presentó nódulos por calcificación en la zona receptora. El resto de los pacientes en estudio no presentó eventos adversos. El grado de satisfacción postratamiento con Nanofat fue de 100 por ciento. Conclusiones: Los resultados de la corrección de las ojeras y del surco nasoyugal con Nanofat son muy buenos(AU)

Introduction: Periorbital aging is considered a complex and multifactorial process that is related to intrinsic and extrinsic processes such as degenerative changes in the skin, appearance of fine lines, volume loss, tissue descent, sagging skin, and excess fat deposition. Objetive: To evaluate the results of correction of dark circles under the eyes and the nasojugal sulcus with Nanofat. Methods: A prospective longitudinal study was performed in the Plastic Surgery and Caumatology Service of the Clinical Surgical Hospital "Hermanos Ameijeiras" from August 2019 to May 2021. The sample consisted of 37 patients. The data were summarized in absolute and relative frequencies. Results: The mean age was 47.2±10.7 years. The 89.2 percent of the patients were women. The mean emulsified tissue infiltrated per side was 1.40±0.4 ml, with a minimum volume of 1 ml and a maximum of 2 ml. In 83.8 percent of the cases there was a decrease in the nasojugal sulcus and in 16.2 percent there was a great improvement. In 100 percent of the patients there was improvement of hyperpigmentation and great improvement of skin quality. Among the complications only one patient (2.7 percent) presented nodules due to calcification in the recipient area. The rest of the patients in the study did not present adverse events. The degree of post-treatment satisfaction with Nanofat was 100 percent. Conclusions: The results of correction of dark circles and nasojugal sulcus with Nanofat are very good(AU)

Treatments of Infra-Orbital Dark Circles by Various Etiologies

Dark circles refer to visible darkness of the infra-orbital areas. Dark circles are a cosmetic concern for many individuals, although not a medical concern. Moreover, clear definitions and possible causes of dark circles have not been elucidated. This study reviews the possible causes and treatment options for dark circles based on a review of the medical literature and the authors' clinical experience. Potential factors that contribute to dark circles include excessive pigmentation, shadowing due to tear troughs and infra-orbital fat herniation, shadowing due to infraorbital laxity and wrinkles, and thin, translucent skin overlying the orbicularis oculi muscle. Given the different possible causes for dark circles, therapeutic modalities must be individualized for each patient. Because various factors cause dark circles, it is useful to identify the underlying causes in order to select the appropriate treatment.

Assessment of Efficacy and Safety of Fixed Dose Combination of 3% Biophytex LS 8740 and 5% Proteasyl TP LS 8657 Cream in the Treatment of Under Eye Dark Circles (Infra-orbital Hyperchromia).

Background: Under Eye Dark Circles is attributed to multiple factors. The treatment should address the various pathologies involved to provide the best possible effects. Aims: To assess the efficacy and safety of Wunder eye cream (a combination of 3% Biophytex LS 8740 and 5% Proteasyl TP LS 8657) in patients with under eye dark circles. Study Design: Open label, prospective, single arm and multicentric post marketing surveillance clinical study. Materials and Methods: 142 patients (125 males and 17 females) were evaluated in the study. Wunder Eye cream was applied twice daily on the affected under eye dark circle area for eight weeks. Parameters evaluated were area of under eye pigmentation, improvement in luminance of under eye skin, reduction in under eye puffiness and reduction in under eye wrinkles using a digital camera photographs after four and eight weeks of treatment. Safety evaluation was also done on the same time. The values were compared using Chi-Square test. Results: Early response was seen in 40% of patients with four weeks of treatment where 50% improvement in all the parameters was seen. With eight weeks of therapy about 92.3% of patients showed 50 to 100% improvement in the area of under eye pigmentation; 50% to 75% improvement was seen in 87.3% of patients for under eye pigmentation, in 80.1% patients for luminance of under eye skin, in 68% patients for under eye puffiness and in 67.4% of patients for under eye wrinkles. Conclusion: Wunder eye cream is a combination of botanical and yeast extracts was found to be effective against under eye dark circles.