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1.
Bol. latinoam. Caribe plantas med. aromát ; 14(3): 156-170, mayo 2015. ilus
Article in English | LILACS | ID: biblio-907481

ABSTRACT

Desmostachya bipinnata (L.) Stapf. (Fam. Poaceae) and Imperata cylindrica (L.) P. Beauv. (Fam. Poaceae) also traditionally known as Kusha and Dharbha respectively are two grasses that form vital ingredient in various Vedic sacrifices (Yagnas) and rituals. They are found along river beds and plains throughout India and are well known for their medicinal properties as supported by traditional Ayurvedic scriptures and are a vital component in traditional medicinal formulations such as Tripanchamool, Kusadya-ghrita and Kusablecha, etc. to treat many disorders such as dysentery, diuresis, jaundice, skin infections etc. The current review enlightens the bioactive molecules such as flavonoids, glycosides etc. isolated from these grasses so far. Emphasis is laid on the various therapeutic applications of extracts or biomolecules characterized from these medicinal grasses. Reports of antimicrobial, diuretic, anti-ulcerogenic and other activities from both of these plants suggest involvement of various bioactive principles. Also, the future perspectives concerned with medicinal properties of these sacred grasses is discussed.


Desmostachya bipinnata (L.) Stapf. (Fam. Poaceae) e Imperata cylindrica (L.) P. Beauv. (Fam. Poaceae) también conocida tradicionalmente como Kusha y Dharbha respectivamente, son dos plantas medicinales que forman un ingrediente vital en diversos sacrificios védicos (yagnas) y rituales. Se encuentran a lo largo de cauces y llanuras en toda la India y son bien conocidos por sus propiedades medicinales apoyadas por escrituras ayurvédicas tradicionales y son un componente vital en formulaciones medicinales tradicionales como Tripanchamool, Kusadya-ghrita y Kusablecha, etc. para tratar muchos trastornos tales como la disentería, la diuresis, la ictericia, infecciones de la piel, etc. La revisión actual resalta las moléculas bioactivas como los flavonoides, glucósidos etc., aislados de estas plantas hasta ahora. Se hace hincapié en las diversas aplicaciones terapéuticas de los extractos o biomoléculas caracterizadas de estas hierbas medicinales. Informes de actividades antimicrobianas, diuréticas anti-ulcerogénicas y otras de estas dos plantas sugieren la participación de varios principios bioactivos. Además, se discutieron las perspectivas de futuro que se ocupan de las propiedades medicinales de estas hierbas sagradas.


Subject(s)
Medicine, Traditional , Plants, Medicinal , Plant Extracts/chemistry , Poaceae/chemistry , India
2.
Rev. bras. farmacogn ; 24(1): 44-50, Jan-Feb/2014. tab, graf
Article in English | LILACS | ID: lil-710153

ABSTRACT

Desmostachya bipinnata (L.) Stapf, Poaceae, or Kusha in Sanskrit, is a sacred grass used extensively in Indian Vedic practices. It is well known for its medicinal value and is used in traditional Indian medicine to treat microbial infection in combination with other herbs. An effort has been made to isolate and characterize the bioactive compounds from the hydroalcoholic extract of D. bipinnata through bioassay guided fractionation, column chromatography. Their individual or combined antimicrobial properties were determined by the Resazurin Microtitre Assay, the checkerboard assay in combination with antibiotics, and by time kill curve analysis. β-Sitosterol-D-glucopyranoside was the bioactive compound identified to have the best antimicrobial activity (MIC 6-50 µg/ml) and it works synergistically with most antibiotics, especially with ciprofloxacin. Time kill curves showed that BS kills most of the pathogens within 5-10 h. To our knowledge at its best, this is the first time report of antibacterial synergy of β-sitosterol-D-glucopyranoside from D. bipinnata.

3.
Article in English | LILACS | ID: lil-613286

ABSTRACT

Desmostachya bipinnata root has been used in the Indian traditional system of medicine for treatment of diarrhoea and dysentery. The antidiarrhoeal effect of both alcoholic and aqueous extracts of the roots of Desmostachya bipinnata were studied in rats against castor oil induced diarrhoea and charcoal meal test at the doses of 200 and 400 mg/kg body weight. The alcoholic extract and to a lesser extent aqueous extract significantly reduced the weight of the faces and decreased the propulsion of charcoal meal through the gastrointestinal tract. The phytochemical screening of the extracts showed the presence of alkaloids, glycosides, flavonoids, tannins, phytosterol, terpenoids, polyphenolics, protein and carbohydrates. These results may support the fact that this plant is used traditionally to cure diarrhoea.


La raíz de Desmostachya bipinnata ha sido utilizada en el sistema tradicional de medicina Hindú para el tratamiento de diarrea y disentería. El efecto antidiarreico de los extractos alcohólicos y acuosos de los extractos de la raíz de Desmostachya bipinnata fueron estudiados en ratas, utilizando la diarrea inducida por aceite de castor y el ensayo de la prueba por carbón en dosis de 200 y 400 mg/kg de peso corporal. El extracto alcohólico y en menor grado, el extracto acuoso, redujeron significativamente la propulsión de carbón a través del tracto gastrointestinal. El análisis de los extractos mostrarón la presencia de alcaloides, glicósidos, flavonoides, taninos, fitoesterol, terpenoides, polifenoles, proteínas y carbohidratos. Estos resultados pueden apoyar el hecho de que esta planta sea usada tradicionalmente para curar la diarrea.


Subject(s)
Animals , Rats , Antidiarrheals/pharmacology , Diarrhea/drug therapy , Ethanol/pharmacology , Plant Extracts/pharmacology , Poaceae/chemistry , Plant Roots/chemistry , Castor Oil , Diarrhea/chemically induced , Gastrointestinal Motility , Rats, Wistar
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