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Objective To study the therapeutic value of endoscopy for primary duodenal lesions. Methods Data of 79 consecutive patients with primary duodenal lesions, who underwent endoscopic treatment from January 2015 to January 2018 at Beijing Friendship Hospital, were retrospectively analyzed. Patients were divided into the complication group and the non-complication group, and further grouped according to lesion locations and endoscopic categories. Baseline data of patients, endoscopic treatment, wound closure method, pathological results, the occurrence and outcome of complications were studied. Results A total of 79 patients successfully went through endoscopic treatment, including 59 cases of endoscopic mucosal resection ( EMR) , 5 cases of endoscopic submucosal dissection ( ESD) , 6 cases of full-thickness resection with OTSC metal clips, and 9 cases of endoscopic piecemeal mucosal resection ( EPMR) . In all 79 cases, complications occurred in 8 patients ( 10. 1％) during the perioperative period, all at the duodenal descending segment and duodenal papilla. In all 47 cases whose lesions located at duodenal papilla and duodenal descending segment, the complication incidence was 17. 0％ ( 8/47) , significantly higher than that of non-descending and papilla part [ 0 ( 0/32 ) , P=0. 012 ] . Two ( 2. 5％) cases had complications requiring further intervention with endoscopy or surgery. Among 8 patients with complications, 1 patient ( 2. 1％) developed intraoperative perforation, 1 patient ( 2. 1％) developed delayed bleeding, 6 patients ( 12. 8％) developed mild acute pancreatitis, and these 8 patients recovered after treatment. These 47 patients were further divided into the duodenoscopy group and the gastroscopy group according to endoscopic categories, the complications incidence in the duodenoscopy group ( 28. 0％, 7/25) was also significantly higher than that in the gastroscopy group [ 4. 5％( 1/22) , P=0. 037] . Conclusion Endoscopic treatment is safe and effective for primary duodenal lesions. But for the operations in the duodenal descending segment and the duodenal papilla, as well as in the case of duodenoscopy, it is necessary to be more vigilant about the occurrence of complications.
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Objective To evaluate the clinical significance of juxtapaillary duodenal diverticula (JPDD) in patients of acute calculous cholangitis (AC) with different severity grade.Methods A retrospective analysis was carried out for 488 AC cases of different severity from January 2011 to December 2013 who underwent duodenoscopy in Dongyang People's Hospital.Results Of the 488 patients, the JPDD was found in 2.87％, 6.15％ and 4.10％ in patients with mild, moderate and severe AC, respectively.The prevalence of JPDD in severe AC were significantly higher in the moderate and mild AC (x2 =4.486, P =0.034;x2 =14.686, P ＜ 0.001);Procalcitonin (PCT) concentrations in severe AC of JPDD were significantly higher in moderate and mild AC of JPDD (t =10.420 9, P ＜ 0.001;t =4.870 4, P ＜ 0.001).The cannulation failure rate and the amylase were significantly higher in JPDD patients compares to patients without JPDD (x2 =36.95, P ＜ 0.001;t =8.29, P ＜ 0.001).Conclusions JPDD detection rate increases with aging and seems to be associated with acute cholangitis (AC) with different severity grade and PCT concentration.JPDD predicts a higher cannulation failure rate and the amylase level after duodenoscopy.
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La úlcera péptica es una lesión en la mucosa gastrointestinal (estómago o duodeno) que se extiende más allá de la muscularis mucosae y que permanece como consecuencia de la actividad de la secreción ácida del jugo gástrico. Objetivo: describir las características epidemiológicas y clínicas de las úlceras gástricas y duodenales en pacientes que acudieron al servicio de videoendoscopías del Centro Médico Alta Tecnología Hernando Dionisio Amaya Benavides de Tucupita en Venezuela, en el periodo 2010-2013. Material y métodos: se realizó un studio descriptivo de corte transversal. Se revisaron 1972 expedientes de pacientes mayores de 15 años, procedentes de instituciones médicas de Barrio Adentro, estatales y privadas, que acudieron al servicio de videoendoscopía del Centro Médico de Alta Tecnología Hernando Dionisio Amaya Benavides de Tucupita, en el periodo 2010-2013. Se estudiaron variables demográficas y clínicas. Resultados: la morbilidad por úlceras pépticas resultó de 9,83%, diagnosticado en 105 pacientes, con mayor frecuencia en el sexo masculino en edades comprendidas entre 45 y 54 años. La principal procedencia en el caso de las úlceras gástricas es de los consultorios médicos populares (CMP), presente en 36 pacientes; en el caso de las duodenales, los procedentes de servicios estatales. La porción más afectada por úlceras gástricas en estómago fue el antro, con 110 úlceras diagnosticadas (94%) y en el duodeno, cara anterior del bulbo, con 51 úlceras de las registradas en esta porción (50%). Conclusiones: la úlcera gástrica es más frecuente que la duodenal, la epigastralgia constituyó el síntoma principal que motivó el estudio en los pacientes ulcerosos. La labor de enfermería contribuye a la realización efectiva en el servicio de videoendoscopía.
Peptic ulcer is an injury to the gastrointestinal mucosa (stomach and duodenum) extending beyond the muscularis mucosae and which remains as a result of the activity of acid secretion in the gastric juice. Objetive: To describe the epidemiological and clinical characteristics of gastric and duodenal ulcers in patients who attended the service videoendoscopias Medical Center of High Technology Dionisio Hernando Amaya Benavides Tucupita in Venezuela, in the 2010 period features-2013. Material and methods: Came on descriptive cross-sectional study. 1972 records of patients older than 15 years, from Barrio Adentro medical institutions, state and private, who atttended the service of High Technology videoendoscopy Dionisio Hernando Amaya Benavides Tucupita in 2010-2013 Medical Center were reviewed. Demographic and clinical variables were studied. Results: Peptic ulcer morbidity was 9.83%, diagnosed in 105 patients, most often in men aged between 45 and 54 years. The main origin in the case of gastric ulcers is popular medical practices (CMP), present in 36 patients; in case of duodenal, those from government services. The most affected by gastric ulcers in stomach antrum portion was with 110 diahgnosticadas ulcers (94%) and in the duodenum, anterior bulb with 51 ulcers recorded in this portion (50%). Conclusions: Gastric ulcer is more frequent than duodenal, epigastric pain was the main symptom that motivated the study ulcer patients. The nursing work contributes to the effective realization of videoendoscopy service.
Subject(s)
Humans , Male , Middle Aged , Duodenal Ulcer/epidemiology , Stomach Ulcer/epidemiology , Peptic Ulcer/diagnosis , Epidemiology, Descriptive , Cross-Sectional StudiesABSTRACT
El carcinoma de duodeno constituye una patología infrecuente y por lo tanto no es tenida en cuenta en los diagnósticos diferenciales de los cuadros obstructivos altos. A continuación se presenta un caso correspondiente a este tipo de lesión manejado en el servicio de cirugía del Hospital Universitario de Santander...
The duodenal carcinoma constitutes an infrequent pathology and therefore it is not taken into account as a differential diagnosis of high obstructive symptoms. Subsequently its presented a case pertaining to this type of wound handled in the service of surgery of the Hospital Universitario de Santander...
Subject(s)
Adenocarcinoma , Duodenal Diseases , Duodenal NeoplasmsABSTRACT
Magaldrat, a chemical combination of aluminum and magnesium hydroxides was synthesized from aluminum compounds and magnesium sulfate. The factors, which influence the result, have been investigated. The quality of magaldrate has also been analyzed following the standards of USP XXIII. The product showed low acute and chronic toxicity in vivo.