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The article presents an original method for the automatic assessment of the quality of event-related potentials (ERPs), based on the calculation of the coefficient ε, which describes the compliance of recorded ERPs with some statistically significant parameters. This method was used to analyze the neuropsychological EEG monitoring of patients suffering from migraines. The frequency of migraine attacks was correlated with the spatial distribution of the coefficients ε, calculated for EEG channels. More than 15 migraine attacks per month was accompanied by an increase in calculated values in the occipital region. Patients with infrequent migraines exhibited maximum quality in the frontal areas. The automatic analysis of spatial maps of the coefficient ε demonstrated a statistically significant difference between the two analyzed groups with different means of migraine attack numbers per month.
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Humans , Chronic Pain , Evoked Potentials , Migraine Disorders/psychology , Occipital Lobe , ElectroencephalographyABSTRACT
Objective:To explore the difference of perceptual processing in ERP between cartoon faces and real faces.Methods:Thirty college students were selected and adopted the face recognition paradigm.The independent variables were face type (real, cartoon) and emotional type (positive, neutral, negative). The dependent variables were response time and the amplitude and latency of ERP data.SPSS 22.0 software was used for repeated measurement analysis of variance.Results:The reaction time of cartoon expression ((455.58±55.18)ms) was shorter than that of real face ((471.49±63.02)ms) of college students.There was no significant difference in N170 amplitude and latency among different faces and expressions(all P>0.05). The vertex positive potential VPP latency of positive real faces ((159.89±13.93)ms) was shorter than that of positive cartoon faces ((165.68±14.35)ms) ( PVPP<0.05). It was easily affected by perceptual load, but negative emotion was not affected by it.In the late processing stage of late positive potential(LPP), the amplitude of positive emotional real face ((10.4±1.22)μV) was higher than that of cartoon ((4.26±0.53)μV), and that of negative emotional cartoon face ((3.84±0.36)μV) was higher than that of real face ((1.9±0.24)μV) ( PLPP<0.05). Conclusion:There are no differences in early stage N170, and the late processing stage, the real faces have an overall advantageous effect on positive emotion, and the local characteristics of negative emotional cartridge wells are more superior.
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Abstract Introduction Tinnitus is sound perception in the absence of a sound source. Changes in parameters of latency and amplitude on the auditory event related potentials or long latency potentials waves have been cited in tinnitus patients when compared to a control group. Objective To perform an assessment of scientific evidence that verifies the possibility of alterations in latency or amplitude of the waves of event related potentials in individuals with tinnitus. Methods By using SciELO, Lilacs, ISI Web and PubMed, scientific databases, a review was performed. Articles published in English, Portuguese, French and Spanish that correlated tinnitus with changes in event related potentials were included in this review. Results Twelve articles were located, however only eight fulfilled the criteria for inclusion. Conclusion The sample of selected studies demonstrate that the long latency auditory evoked potentials related to events between the control and tinnitus patients showed some changes in latency and or amplitude in tinnitus patients. There are changes in event-related potentials when comparing patients with tinnitus and the control group. These changes take place considering the severity of tinnitus, tinnitus site of lesion, and capacity for changes after interventions. The event related potentials can help to determine the neurotransmitter involved in tinnitus generation and evaluate tinnitus treatments.
Resumo Introdução O zumbido é a percepção de um som na ausência de uma fonte sonora. Mudanças nos parâmetros de latência e amplitude nas ondas dos potenciais evocados auditivos relacionados a eventos ou potenciais de longa latência foram citadas em pacientes com zumbido quando comparados a um grupo controle. Objetivo Realizar uma avaliação de evidências científicas que verifiquem a possibilidade de alterações na latência ou amplitude das ondas de potenciais evocados auditivos relacionados a eventos em indivíduos com zumbido. Método Foi feita uma revisão a partir dos bancos de dados científicos SciELO, Lilacs, ISI Web e PubMed. Artigos publicados em inglês, português, francês e espanhol que correlacionavam zumbido com alterações nos potenciais evocados auditivos relacionados a eventos foram incluídos. Resultados Foram localizados 12 artigos, porém apenas oito preencheram os critérios de inclusão. Conclusão A amostra de estudos selecionados demonstra que os potenciais evocados auditivos de longa latência relacionados a eventos entre os pacientes-controle e com zumbido apresentaram algumas alterações na latência e/ou amplitude nos pacientes com zumbido. Há mudanças nos potenciais relacionados a eventos ao comparar pacientes com zumbido e o grupo controle. Essas alterações consideram a gravidade do zumbido, o local da lesão do zumbido e a capacidade de alterações após as intervenções. Os potenciais evocados auditivos relacionados a eventos podem ajudar a determinar o neurotransmissor envolvido na geração do zumbido e avaliar os tratamentos para o zumbido.
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Humans , Tinnitus/physiopathology , Evoked Potentials/physiology , Evoked Potentials, Auditory/physiology , Attention , Tinnitus/psychology , Event-Related Potentials, P300/physiology , Evidence-Based MedicineABSTRACT
Objective • To explore the differences of event-related potential components (N400 and P600) in response to language processing between schizophrenia (SZ) patients with formal thought disorder (FTD), SZ patients without FTD, genetic high-risk subjects and healthy controls (HC). Methods • Thirty SZ patients with FTD (SZ-FTD group) and 29 SZ patients without FTD (SZ-nFTD group), who were hospitalized in Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 22 subjects at genetic high risk who were first degree relatives of SZ patients, and 31 healthy controls (HC) were recruited. Four different types of sentences (syntactically and semantically correct, syntactically correct but semantically incorrect, syntactically incorrect but semantically correct, and syntactically and semantically incorrect) were presented to the four groups respectively with electroencephalogram recording. Repeated measurement analysis of variance was used to compare the response accuracy of the four groups and to analyze the differences in the amplitude and latency of N400 and P600 components in response to each kind of sentence among the four groups. Results • SZFTD group showed a lower accuracy rate compared with the HC group (P=0.000). Compared with the HC group, N400 amplitude in SZ-FTD group was lower in statistically significance (P=0.003), while SZ-FTD group did not show a prominent N400 component. P600 component was well evoked in four groups, and there was an interaction between semantics, syntax and group (P=0.022). By further analysis, neither SZ-FTD nor SZ-nFTD group showed significant differences in P600 amplitudes evoked by syntactically correct and syntactically incorrect sentences. There was no significant difference in P600 amplitudes evoked by semantically correct and incorrect sentences in SZ-FTD group, whereas P600 amplitudes evoked by semantically correct sentences were greater than those evoked by semantically incorrect ones in the other three groups. Conclusion • Neural activity is impaired during semantic processing in SZ. In particular, SZ-FTD patients have impairments in both semantic and syntactic processing.
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Antecedentes: los programas fast-track en cirugía hepática muestran ventajas con respecto al manejo perioperatorio tradicional al favorecer principalmente una disminución de la estancia hospitalaria y, por ende, de los costos hospitalarios. Material y métodos: en un estudio observacional y descriptivo se analizan resecciones hepáticas abiertas dentro de un programa de recuperación rápida, haciendo especial hincapié en la adherencia a este, la recuperación total de los enfermos, la morbilidad y la estancia hospitalaria. Resultados: se realizaron 32 hepatectomías en 30 pacientes, 27 de los cuales fueron oncológicos. La adherencia al programa utilizado fue del 78,1% y la recuperación total al momento del alta del 75%. La morbilidad fue del 12,5% y las complicaciones fueron de baja complejidad, aunque 2 pacientes necesitaron reingresar. La estancia hospitalaria tuvo una media de 3,4 días y, sumando los reingresos, de 3,6 días. Conclusión: la aplicación de un ERP en cirugía hepática no solo es factible sino trae aparejada como principal beneficio una disminución en la estancia hospitalaria y, por ende, de los costos. Pero no estamos convencidos de que un ERP mejore la morbilidad de los pacientes.
Background: Background: Fast-track programs in liver surgery offer advantages over traditional perioperative management, particularly in terms of reducing length of hospital stay and hospital costs. Material and methods: We conducted an observational and descriptive analysis of patients undergoing open liver resections as part of an enhanced recovery program. Adherence to the program, full recovery of the patients, complications and length of hospital stay were assessed. Results: A total of 32 liver resections were performed in 30 patients, 27 with cancer. The adherence to the program was 78.1% and full recovery on discharge was 75%. The incidence of complications was 12.5%; most of them were not severe but two patients required rehospitalization. Mean length of hospital stay was 3.4 days and 3.6 days when readmissions were considered. Conclusion: The implementation of an ERP after liver resections is feasible and offers advantages in terms of reducing length of hospital stay and hospital costs. We do not think that ERP improves morbidity in these patients.
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Objective To compare the amplitude and latency of event-related potential P300 be-tween impulsive and predictive violent criminals. Methods Twenty impulsive violent criminals and twenty predictive violent criminals were recruited from one prison in Wenzhou city. Twenty matched healthy controls from community were recruited. Criminals in both groups were excluded from violent crimes caused by mental disorders by judicial psychiatrists using DSM-IV axis I disorder clinical stereotyped interviews. Nicolet Bravo Brain Evoked Potentiometer (produced by Nicolet Company,USA) was used to detect the P300 components of the above three groups of subjects. Eysenck Impulsiveness Scale was used to assess the impulsiveness. Results The P300 amplitude of impulsive violent criminals was smaller than that of predictive violent crimi-nals( (4. 52±1. 14)μV vs (13. 88±2. 06)μV,t=17. 779,P<0. 01),but there was no significant difference of the P300 amplitude between predictive violent criminals and community enrolled controls ((13. 88±2. 06) μV vs (14. 01±1. 86)μV,t=0. 209,P=0. 835). The impulsivity scale score of impulsive violent criminals was highly negatively correlated with the amplitude of P300 (r=-0. 812,P=0. 002). There were no signifi-cant differences in the latency of P300 among impulsive violent criminals,predictive violent criminals and community enrolled controls group. And there was no significant correlation between the latency of P300 and the score of impulsivity scale (P>0. 05). Conclusion The P300 amplitude can aid in the differential diag-nosis of violent criminals with and without impulsive behavior.
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Aim To investigate the effect of Radices Paeoniae Alba extract on estrogen receptor (3 ( ERp ) and serotonin transporter(SERT) in the hippocampus of rat model of premenstrual syndrome( PMS) liver-qi inverse syndrome. Methods The rats were randomly divided into the normal group, the model group, the Radices Paeoniae Alba extract group, the fluoxetine group and the ER(3 agonist group by the vaginal smear microscopy and the open field score. The model group rats were prepared by electrical stimulation to prepare PMS liver-qi inverse syndrome. After five days of administration, the hippocampal tissues of each group were separated. ERp and SERT mRNA and protein expression in each group were determined by RT-PCR and immunofluorescence histochemical method. Results During the estrous reception period, there was no significant difference in the behavior score of the open- field test and the expression of ERp and SERT mRNA and protein in the hippocampus of each group. Estrous non-reception period; compared with normal rats, the total distance of open field test in model rats increased significantly. The expression of ER(3 mRNA in hippocampus significantly decreased and SERT mRNA significantly increased. In model group, the pyramidal cells in hippocampal CA1 and CA3 brain areas of rats were irregularly arranged, and the number of ERp positive cells and protein expression decreased. The number of SERT positive cells and protein expression were significantly up-regulated. After the Radices Paeoniae Alba extract was given, the above indexes were significantly improved, and no significant difference was found between them and fluoxetine group and ER agitator group. Conclusions Radices Paeoniae Alba extract may adjust the PMS card of diseases with inverse nega-tive emotions possibly by improving the hippocampus ER|3 and SERT mRNA and protein expression.
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Resumo O objetivo deste estudo é investigar o efeito da demanda cognitiva prolongada na modulação do Potencial Relacionado a Evento (ERP) em um paradigma de controle inibitório. Os dados foram coletados em 19 voluntários destros, com a média de idade de 21,21 (±1,77) anos, que realizaram o paradigma do Go/NoGo durante 50 minutos, com gravação sincronizada do eletroencefalograma para obtenção dos ERPs. O efeito do tempo de realização da tarefa provocou alterações significativas nas variáveis subjetivas, de desempenho cognitivo e nas amplitudes máximas dos componentes N2 e P3. Nossos resultados sugerem que quando nosso cérebro está submetido a demandas cognitivas extensas, ocorrem adaptações para a manutenção do desempenho comportamental através da estratégia de realocação de recursos energéticos.
Abstract The aim of this study is to investigate the effect of prolonged cognitive demand in Event Related Potential (ERP) modulation in inhibitory control paradigm. Data were collected in 19 right-handed volunteers with mean age of 21.21 (±1,77) years who performed the Go/NoGo paradigm for 50 minutes, with synchronized electroencephalogram recording to obtain the ERPs. The time on task effect induced significant changes in subjective variable, cognitive performance and maximum amplitudes of the N2 and P3 component. Our results suggest that when our brain is subjected to extensive cognitive demands, there are adaptations to maintain the behavioral performance through strategy reallocation of energy resources.
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Resumen Introducción: La tecnología avanza a pasos agigantados a través del tiempo, este ha sido uno de los factores más importantes para las empresas, porque les ha permitido mejorar sus procesos, decisiones en pro de obtener mayores utilidades y beneficios. Muchas empresas han decidido implantar un sistema ERP con la finalidad de mejorar la gestión de información a través de la automatización de procesos operativos y es que les ha dado resultados positivos a través del tiempo. Es así que la empresa Acero Comercial Ecuatoriana S.A y Ferro Torre S.A deciden aplicar este sistema puesto que presentaban problemas en la eficiencia de la gestión financiera en el 2016. Objetivo: El objetivo de la investigación fue comprobar la eficiencia en la gestión financiera mediante la aplicación de ERP. Materiales y métodos: La investigación se apoya en un enfoque cuantitativo, partiendo de los estados financieros de las empresas Acero Comercial Ecuatoriano S.A y Ferro Torre S.A de los años 2016 y 2017. Resultados: Se comprueba la hipótesis: existe eficiencia en la gestión financiera de la empresa Acero Comercial Ecuatoriano S.A y Ferro Torre S.A mediante la aplicación de ERP. Luego de tomar las principales cuentas del Estado de Resultados de la empresa Acero Comercial Ecuatoriana S.A y Ferro Torre de los años 2016 y 2017. Se tomó en consideración la información financiera de la implantación del ERP en el 2017 realizando una comparativa con el año anterior. A través de los 3 flujos (capital, materia e información) se pudo evidenciar el mejoramiento de la eficiencia de la gestión financiera. Conclusión: Luego de la comparativa porcentual se pudo comprobar que el sistema ERP mejora la eficiencia de la gestión financiera de Acero Comercial Ecuatoriana S.A y Ferro Torre S.A porque se obtuvieron datos positivos en relación a reducción de ajustes de inventario, gastos de personal, devolución en ventas y mantenimiento y la mejora correspondiente en atención al cliente, ventas y capacitaciones.
Abstract Introduction: Technology advances by leaps and bounds through the time, this has been one of the most important factors for companies, because it has allowed them to improve their processes, decisions in favor of obtaining greater profits and benefits. Many companies have decided to implement an ERP system in order to improve information management through the automation of operational processes and that has given positive results over time. Thus, the company Acero Comercial Ecuatoriana S.A and Ferro Torre S.A decided to apply this system since they presented problems in the efficiency of financial management in 2016. Objective: Theobjective of the research was to verify the efficiency in financial management through the application of ERP. Materials and methods: The research is based on a quantitative approach, based on the financial statements of the companies Acero Comercial Ecuatoriano S.A and Ferro Torre S.A of the years 2016 and 2017. Results: The hypothesis is verified: there is efficiency in the financial management of the company Acero Comercial Ecuatoriano S.A and Ferro Torre S.A through the application of ERP. After taking the main accounts of the Income Statement of the company Acero Comercial Ecuatoriana SA and Ferro Torre of the years 2016 and 2017. The financial information of the implementation of the ERP in 2017 was taken into consideration, making a comparison with the previous year. Through the 3 flows (capital, material and information) it was possible to demonstrate the improvement of the efficiency of financial management. Conclusion : After the percentage comparison it was possible to verify that the ERP system improves the efficiency of the financial management of Acero Comercial Ecuatoriana SA and Ferro Torre SA because positive data were obtained in relation to reduction of inventory adjustments, personnel expenses, return on sales and maintenance and the corresponding improvement in customer service, sales and training.
Resumo Introdução: A tecnologia avança aos trancos e barrancos ao longo do tempo, este tem sido um dos fatores mais importantes para as empresas, porque lhes permitiu melhorar seus processos, decisões em favor de obter maiores lucros e benefícios. Muitas empresas decidiram implementar um sistema ERP para melhorar o gerenciamento de informações através da automação de processos operacionais e que tem dado resultados positivos ao longo do tempo. Assim, a empresa Acero Comercial Ecuatoriana S.A e a Ferro Torre S.A decidiram aplicar este sistema, uma vez que apresentavam problemas na eficiência da gestão financeira em 2016. Objetivo: O objetivo da pesquisa foi verificar a eficiência na gestão financeira por meio da aplicação do ERP. Materiais e métodos: A pesquisa é baseada em uma abordagem quantitativa, baseada nas demonstrações financeiras das empresas Acero Comercial Ecuatoriano S.A e Ferro Torre S.A dos anos de 2016 e 2017. Resultados: A hipótese é verificada: há eficiência na gestão financeira da empresa Acero Comercial Ecuatoriano S.A e da Ferro Torre S.A, através da aplicação do ERP. Depois de tomar as principais contas da Demonstração dos Resultados da empresa Comercial Ecuatoriana S.A aço e torre de Ferro 2016 e 2017. Ele levou em consideração as informações financeiras da implementação de ERP em 2017 fez uma comparação com o ano anterior. Através dos 3 fluxos (capital, material e informação) foi possível demonstrar a melhoria da eficiência da gestão financeira. Conclusão: Após a comparação percentual verificou-se que o sistema de ERP melhora a eficiência da gestão financeira do Commercial Aço Ecuatoriana SA e Ferro Torre SA, pois os dados positivos foram obtidos em relação à redução de ajustes de estoque, custos com pessoal, retorno sobre vendas e manutenção e a correspondente melhoria no atendimento ao cliente, vendas e treinamento.
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Objective To investigate the semantic priming of boy with attention deficit hyperactivity disorder( ADHD) and explore whether the semantic priming deficits was associated with behavioral problems by event-related potential(ERP). Methods Thirty boy with and without ADHD aged from 7 to 13 years were asked to finish the semantic Semantic judgment task. The study took advantage of t-test ( independent-samples) to compare the amplitude and latency of the N400 in both groups,as well as behavioral data.Behav-ioral problems were assessed by the Achenbach child behavior checklist( CBCL) ,and Pearson correlation a-nalysis were used to explore the relationship between behavioral problems and semantic priming. Result-s Under the condition of semantic correlation,the hyperactive factor of CBCL in ADHA group was positively correlated with ERP N400 amplitude ( r=0.44,P<0.05) and negatively correlated with reaction accuracy ( r=-0.48,P<0.05).Under the semantic irrelevant condition,the latency of ERP N400 in ADHA group was pos-itively correlated with hyperactivity factor (r=0.53,P<0.05)and aggression factor of CBCL(r=0.62,P<0.05).The N400 amplitude of the ADHD group was significant higher than that in the control group under se-mantic related conditions((-11.36±4.77)μV vs (-7.66±5.24)μV,P=0.006),and the latency of the N400 in ADHD was more delay((369.6±44.09)ms vs (341.27±24.54)ms,P=0.004),and the reaction times (RT) was much longer((936.18±135.03)ms vs (857.78±103.45)ms,P=0.014).The latency of the N400 in ADHD was more delay than that in the control group under semantic irrelevant conditions ( ( 383. 93 ±29.66)ms vs (362.33±29.66)ms,P=0.012),and accuracies of ADHD group was lower than that of control group(0.43±0.39 vs 0.81±0.23,P<0.01).Conclusion The present result indicates that children with ADHD exhibit a deficit in the semantic priming mechanism,and the deficit is positively correlated with hy-peractivity and impulsiveness.
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Objective Rats were fed with high-fat diet and were successfully induced the models with non-alcoholic fatty liver disease,and to investigate the effects of liraglutide on the expression of ERp46.Methods Thirty male Sprague-Dawley rats were assigned to normal chow group(NC,n=10)and high-fat diet group(n=20),after 12 weeks,the high-fat diet group rats were divided into high-fat diet group(HF,n=10)and liraglutide group(100L,n=10) and treated with normal saline and liraglutide(100 μg/kg)for 4 weeks respectively. Liver tissues were measured by hematoxylin-eosin(HE),Oil Red O staining,hepatic triglyceride(TG),and hyperinsulinemic-euglycemic clamp test(HECT). Hepatocyte apoptosis rate were evaluated by TdT-mediated dUTP nick-end labeling(TUNEL),and the expressions of ERp46 mRNA and protein were measured.Results Compared with the NC group,the liver tissues in the HF group have steatosis,insulin resistance,and the percentage of apoptosis was significantly increased. ERp46 mRNA and protein expressions were decreased(P<0.05). Compared with the HF group,liraglutide treatment was sufficient to reduce steatosis,insulin resistance,apoptosis,and increase the ERp46 mRNA and protein(P<0.05). Furthermore,the expression of ERp46 protein in the liver was negatively correlated with hepatocyte apoptosis rate,and positive correlated with glucose infusion rate(GIR, P<0. 05). Conclusion Liraglutide may up-regulate the expression of ERp46 to improve IR and hepatocyte apoptosis in NAFLD rats.
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Objective To investigate the expression and clinical significance of endoplasmic reticulum protein 29(ERp29) in colorectal cancer. Methods Paraffin-embedded sections from 62 cases of colorectal cancer tissues were obtained and used for immunohistochemical staining of ERp29. The clinical and pathological data of various levels of ERp29 in patients with colorectal cancer were analyzed to determine if there was a significant difference. Results The expression of ERp29 in 62 cases of colorectal cancer tissues, 24(38. 7％ ) cases were positive and 38(61. 3％ )cases were negative. The expression of ERp29 in 62 cases of adjacent tissues, 58 (93. 5％ ) cases were positive and 4(6. 5％ ) cases were negative. There was a significant difference in TNM classification and lymph node metastasis between ERp29 positive group and ERp29 negative group (P ＜ 0. 05 ). Conclusion Colorectal cancer tissues have significantly lower levels of ERp29 than adjacent tissues. ERp29 may be helpful to evaluate the metastatic proclivity and prognosis of colorectal cancer.
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Objective To explore the secondary inventory appropriate to improve the stomatological hospital in cost control for medical consumables,standardizing patient charging,dynamic materials management,zero inventory and enhancing hospital economic benefit.Methods An enterprise resource planning (ERP) secondary inventory information system was developed to solve the problems in medical materials management of the stomatological hospital,and then went through practical trials in three departments to determine its efficacy and deficiencies.Results The information system facilitated cost control,standardized patient charging,and the trials in three departments showed the rate for material consumption was decreased greatly.The deficiencies still existed in the traceability,mobile App,manual input and etc.Conclusion The ERP secondary inventory information system reduces the running cost of the department,increases the hospital abilities in cost control and management,and thus is worthy promoting practically.
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Objective To investigate the effect of butylphthalide on the memory,movement and ERP (event-related potentials) in patients with cerebral infarction cognitive impairment.Methods A total of 134 patients with cerebral infarction cognitive impairment were randomly divided into treatment group (67 patients) and control group (67 patients).All patients were given conventional cerebral infarction treatment as well as cognitive improvement intervention.Oral administration of butylphthalide was added onto the patients in the treatment group.Curative effects were observed after 30 days′ continued treatment.The cognitive function scores,memory scores,movement scores,ERP test and adverse reaction were compared between the two groups before and after treatment.Results After 30 days′ treatment,two groups of the montreal cognitive assessment scale (MoCA) scores were 27.2±4.9 and 25.1±4.1 respectively;the total scores of memory were 5.5±0.5 and 4.9±0.5 respectively;the scores of motor assessment scale (Fugl-meyer) were 85.6±6.2 and 74.2±6.1 respectively and P3 amplitudes were (9.5±0.9)μV and (8.1±0.9)μV respectively.All the indexes mentioned above in treatment group were significantly increased compared with those of before treatment(P<0.05).The results of N1,N2,P2 and P3 in the latency detection were significantly decreased compared with those of before treatment(P<0.05).And the results of P2 and P3 in the latency detection of the treatment group were shorter than those of the control group(P<0.05).After treatment,no adverse reaction was observed in both groups.Conclusion Based on conventional cerebral infraction treatment,oral administration of butyraldehyde effectively improve the therapeutic effect.
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This study was aimed to explore the immediate effect mechanism of the middle 2/5 of the vertex-temporal anterior oblique line in the treatment of stroke by scalp acupuncture using event-related brain potential (ERP).A total of 30 stroke cases who met the inclusion criteria and 25 healthy subjects were selected.Patients in both groups were treated by scalp acupuncture,with stimulation on the middle 2/5 of the vertex-temporal anterior oblique line on the right side.ERP was detected before acupuncture and 10 min after acupuncture in both groups.The muscle strength and neurological deficit score of the stroke group were also detected.At the end of the experiment,the movement-related cortical potentials (MRCPs) of both the left and right hand were extracted from the ERP.The results showed that after 10 min scalp acupuncture stimulation,the neurological deficit score of the stroke group was lower than that of the pretreatment (P ＜ 0.05);the muscle strength rating was higher than before (P ＜ 0.05).Before and after acupuncture,the amplitude of MRCPs on the diseased side of the stroke group was significantly decreased compared to before (P ＜ 0.05).It was concluded that the immediate effect of scalp acupuncture treatment of hemiplegia patients with stroke was definite.Its mechanism may be that acupuncture stimulates the motor cortex through the vertex-temporal anterior oblique line,reduces the energy loss of brain motion planning,activates the damaged brain movement related area cortex neurons,improves the processing efficiency of movement in the brain,so as to promote the improvement of hemiplegic limb motor function immediately.And we also observed that the healthy side brain has a compensatory effect,which suggested that in our clinical scalp acupuncture,bilateral stimulation may be more effective.
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La implementación de un sistema de información es una actividad que requiere análisis y planificación acordes con el impacto que esta actividad pueda implicar para la organización; en este sentido, el objetivo principal de este artículo es dar a conocer el impacto organizacional que se genera durante el proceso de implementación de un sistema de información -ERP tomando como caso de estudio la empresa Comestibles SAS que adelantó este proceso durante el período 2013 - 2014. La investigación se desarrolló bajo un enfoque cuantitativo y cualitativo, con la participación de 61 personas involucradas en el proceso de implementación del sistema de información. Entre los principales resultados en las dimensiones organizacionales se puede mencionar que el mayor impacto positivo se refleja en la dimensión política de la organización; sin embargo, en las dimensiones económica, social y tecnológica se evidenciaron dificultades en el proceso que generaron impactos negativos; estos resultados pueden ser útiles para empresas con características similares al caso de estudio, que decidan asumir el reto de implementar este tipo de sistemas ERP con todos los cambios y riesgos que esto conlleva en el orden organizacional.
The implementation of an information system is an activity that requires analysis and planning according to the impact that this activity may involve for the organization; In this sense, the main objective of this article is to present organizational impact generated during the process of implementing an information system -ERP taking as a case study company Comestibles SAS forward this process during the period 2013 - 2014. the research was conducted under a quantitative and qualitative approach, with the participation of 61 people involved in the process of implementation of the information system. Among the main results in organizational dimensions it may mention that the greatest positive impact is reflected at the level of the political dimension of the organization; however in the economic, social and technological dimensions difficulties evidenced in the process that generated negative impacts; these results may be useful for companies with similar to the case study that decide to take on the challenge of implementing this type of ERP systems with all changes and risks involved at the organizational level features.
A implementação de um sistema de informação é uma atividade que requer análise e planejamento em linha com o impacto que esta atividade pode envolver para a organização; neste sentido, o principal objetivo deste artigo é apresentar impacto organizacional gerado durante o processo de implementação de um sistema de informação -ERP tomando como uma empresa de estudo de caso Comestibles SAS por diante este processo durante o período de 2013 - 2014. a pesquisa foi realizada sob uma abordagem quantitativa e qualitativa, com a participação de 61 pessoas envolvidas no processo de implementação do sistema de informação. Entre os principais resultados em dimensões organizacionais pode mencionar que o maior impacto positivo se reflete na dimensão política da organização; no entanto, nas dificuldades dimensões econômicas, sociais e tecnológicas que era evidente no processo que gerou impactos negativos; Estes resultados podem ser úteis para as empresas com similar ao estudo de caso, eles decidem assumir o desafio de implementar este tipo de sistemas ERP com todas as mudanças e riscos envolvidos nas características de ordem organizacional.
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The complex multidimensional visual patterns of facial expression is particularly well sui ted for studying perception and the processes underlying perceptual integration of component parts into a meaningful whole.With the high resolution in milliseconds,event-related potential (ERP) may be an excellent technique to track the time course of cognitive processing for facial emotions.Facial affective stimuli elicit particular ERP components involved in early processing of facial expressions,including:early sensory processing of visual stimuli:the P100;early structural encoding of facial features:the N170;second-order sustained activities necessary for consequent deeper processing:the posterior P2 and decoding of facial features to identify emotional content:the N250.We reviewed above mentioned ERP components respectively,in order to add the knowledge about ERP components as indicators of neural dynamics of facial emotion processing,and to provide a point of reference for further exploration on facial emotion processing that may be useful for understanding human cognition development and pathology.
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OBJECTIVES: The goal of this study is to measure the auditory Event Related Potentials in Filipino patients with schizophrenia, their siblings and comparing them with normal controls. Specifically the P300 amplitude and latency measurements of schizophrenic patients would also be correlated to sociodemographic variables such as age, duration of illness and positive and negative symptoms of schizophrenia.METHODOLOGY: Patients with schizophrenia after consenting to participate in the study were screened using the Positive and Negative Symptom Scale. The auditory event related potentials (ERP) of the parietal electrode of these patients and their siblings as well as a control group of healthy individuals from the community were measured and compared.RESULTS: Comparison of P300 parameters among 20 patients with schizophrenia, 20 siblings and 20 controls using ANOVA showed that the P300 amplitude of schizophrenic patients was markedly reduced compared with the other 2 groups. P300 latency values were markedly prolonged in both schizophrenia and their siblings when compared to the control group. Analysis of the data revealed that P300 latency had a positive correlation with the duration of positive and negative symptoms. There was also an inverse correlation with positive symptomatology.CONCLUSION: There was a decreased P300 amplitude and prolonged P300 latency in Filipino Schizophrenic patients. P300 parameters in schizophrenic patients were correlated to age, duration of symptoms and positive and negative symptoms.
Subject(s)
Humans , Male , Female , Schizophrenia , Patients , PhilippinesABSTRACT
OBJECTIVES: Memory impairment is a very important mental health issue for elderly and adults. Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Early detection of the prodromal stage of patients with AD is an important topic of interest for both mental health clinicians and policy makers. METHODS: Electroencephalograpgy (EEG) has been used as a possible biological marker for patients with MCI, and AD. In this review, we will summarize the clinical implications of EEG and ERP as a biological marker for AD and MCI. RESULTS: EEG power density, functional coupling, spectral coherence, synchronization, and connectivity were analyzed and proved their clinical efficacy in patients with the prodromal stage of AD. Serial studies on late event-related potentials (ERPs) were also conducted in MCI patients as well as healthy elders. Even though these EEG and ERP studies have some limitations for their design and method, their clinical implications are increasing rapidly. CONCLUSION: EEG and ERP can be used as biological markers of AD and MCI. Also they can be used as useful tools for early detection of AD and MCI patients. They are useful and sensitive research tools for AD and MCI patients. However, some problems remain to be solved until they can be practical measures in clinical setting.
Subject(s)
Adult , Aged , Humans , Administrative Personnel , Alzheimer Disease , Biomarkers , Electroencephalography , Evoked Potentials , Memory , Mental Health , Methods , Cognitive Dysfunction , Prodromal SymptomsABSTRACT
Using the enterprise resource planning(ERP)management mode,the paper analyzed the present medical insurance payment audit accounts at public hospitals,and probed into the establishment of an information management platform for medical insurance payment audit accounts in the ERP environment.The purpose is to perfect the management of medical insurance payment audit accounts,increase the efficiency of hospital's working capital,strengthen the quality and efficiency of hospital management.