ABSTRACT
Introduction: Hereditary gingival fibromatosis is a rare disorder with a genetic component that may appear during tooth replacement. This condition can cause functional and aesthetic problems such as malocclusions, diastemas, pain when chewing, dental caries, periodontal disease, delayed eruption, among others. Objective: To report the multidisciplinary treatment provided to a patient with hereditary gingival fibromatosis. Case Report: This report describes the treatment carried out in a thirteen-year-old male patient presenting generalized increase in gingival volume associated with functional and aesthetic compromise and delayed eruption of permanent teeth. After diagnosis, a multidisciplinary intervention was proposed, involving periodontal and pediatric dentistry procedures, which improved the quality of life of the patient both functionally and aesthetically. Conclusion: Hereditary gingival fibromatosis not only affects the dental eruption process, but also causes aesthetic and emotional alterations in the patient. The periodontal procedures significantly improved the appearance, function, and the psychological state of the patient.
Introducción: La fibromatosis gingival hereditaria es una altera-ción poco común, asociada a un componente genético que en ocasiones se hace evidente en el recambio dentario. Este padecimiento puede generar problemas funcionales y estéticos como maloclusiones, diastemas, dolor al masticar, caries, enfermedad periodontal, erupción tardía, entre otros. Objetivo: Reportar el caso clínico con manejo interdisciplinario en un paciente con fibromatosis gingival hereditaria. Reporte de Caso: Se expone el tratamiento realizado en un paciente de trece años, sexo masculino, con aumento de volumen gingival generalizado con compromiso funcional y estético, conjugado con retraso en la erupción de dientes permanentes. Tras diagnóstico se plantea la intervención multidisciplinaria, integrando áreas como periodoncia y odontopediatría; los procedimientos ejecutados permitieron mejorar la calidad de vida desde el punto de vista funcional y estético. Conclusión: La fibromatosis gingival hereditaria no solo desencadena alteración en proceso eruptivo dental, sino también alteraciones estéticas y emocionales en el paciente que la padece. Los procedimientos perio-dontales realizados permitieron de forma categórica la mejora de la estética, función y estado psicológico del paciente.
Subject(s)
Humans , Male , Adolescent , Fibromatosis, Gingival/surgery , Fibromatosis, Gingival/genetics , Gingiva/pathology , Quality of Life , Pediatric Dentistry , Fibromatosis, Gingival/psychologyABSTRACT
Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition.
Subject(s)
Humans , Female , Child , Fibromatosis, Gingival/pathology , Dentition, Permanent , GingivectomyABSTRACT
Resumen Introducción: la fibromatosis gingival hereditaria es un desorden genético raro que produce un sobre-crecimiento gingival y el desplazamiento dental asociado, la patogénesis y la base molecular de la enfermedad sigue siendo desconocida. Dado que es una enfermedad poco frecuente, es importante que el profesional en el área de la salud oral conozca las características clínicas, histológicas y genéticas de la enfermedad con el objetivo de realizar un correcto diagnóstico, plan de tratamiento y orientación sobre la condición de la patología. Presentación del caso: se reporta informe de una familia con tres generaciones afectadas con fibromatosis gingival hereditaria, en la que se describen las características clínicas, histopatológicas y tratamiento. Conclusión: la fibromatosis gingival hereditaria es un trastorno poco frecuente que genera diversos grados de aumento en el volumen gingival, los compromisos estéticos y funcionales a menudo requieren intervención quirúrgica, histológicamente es común la presencia de abundantes haces de colágeno y fibroblastos.
Abstract Introduction: Hereditary gingival fibromatosis is a rare genetic disorder that produces a gingival overgrowth and the associated dental displacement, the pathogenesis and the molecular basis of the disease remains unknown. Given that it is a rare disease, it is important that the professionals in the field of oral health know the clinical, histological and genetic characteristics of the disease in order to make a correct diagnosis, a treatment plan and the guidance on the condition of the pathology. Case presentation: Report of a family with three generations affected with hereditary gingival fibromatosis, in which the clinical, histopathological and treatment characteristics are described. Conclusions: Hereditary gingival fibromatosis is a rare disorder that generates varying degrees of increase in gingival volume, aesthetic and functional compromises often require surgical intervention, the presence of abundant bundles of collagen and fibroblasts is histologically common.
Resumo Introdução: a fibromatose gengival hereditária é uma desordem genética estranha que produz um so-brecrescimento gengival e o deslocamento dental associado, a patogênese e a base molecular da doença segue sendo desconhecida. Dado que é uma doença pouco frequente, é importante que o profissional na área da saúde oral conheça as características clínicas, histológicas e genéticas da doença com o objetivo de realizar um correto diagnóstico, plano de tratamento e orientação sobre a condição da patologia. Apresentação do caso: reporta-se o informe de uma família com três gerações afetados com fibromatose gengival hereditária, no que se descrevem as características clínicas, histopatológicas e tratamento. Conclusão: a fibromatose gengival hereditária é um transtorno pouco frequente que gera diversos graus de aumento no volume gengival, os compromissos estéticos e funcionais frequentemente requerem intervenção cirúrgica, histologicamente é comum a presença de abundantes feixes de colágeno e fibroblastos.
Subject(s)
Humans , Female , Adolescent , Fibromatosis, Gingival , Surgery, Oral , Therapeutics , Colombia , Rare Diseases , Genetic Diseases, InbornABSTRACT
A Fibromatose Gengival (FG) é descrita como uma condição bucal rara, clinicamente manifestada por um crescimento lento, progressivo, difuso e benigno dos tecidos gengivais. Essa condição pode se manifestar de forma isolada, em associação a outras doenças sistêmicas ou como componente de síndromes. A FG pode ter uma etiologia identificável ou ser idiopática. Em função da severidade de cada caso, pode acarretar transtornos funcionais e estéticos significativos, sobretudo, relacionado à dificuldade de higienização, fala e deglutição, devido à formação de grandes massas teciduais na gengiva. O presente trabalho propõe a revisão dos aspectos clínicos, diagnósticos e terapêuticos da Fibromatose Gengival e relata um caso severo desta doença que foi tratada cirurgicamente... (AU)
The Gingival Fibromatosis (GF) is described as a rare oral condition, clinically manifested by a slow, progressive, diffuse, and benign growth of gingival tissues. This condition can manifest itself in isolation, in combination with other systemic diseases or as a component of syndromes. GF may have an identifiable etiology or be idiopathic. Depending on the severity of each case, GF may result in significant functional and aesthetic disorders, mainly related to the difficulty of cleaning, speech and swallowing due to formation of large gingival tissue masses. This paper proposes a review of the clinical features, diagnosis and treatment of gingival fibromatosis and reports a severe case of this condition that was surgically treated... (AU)
Subject(s)
Humans , Male , Adult , Surgery, Oral , Fibromatosis, Gingival , Gingiva , Gingival Hyperplasia , DeglutitionABSTRACT
La fibromatosis gingival es una enfermedad rara que se caracteriza por aumento del tejido gingival por proliferación fibrosa, es de crecimiento lento, cubriendo en algunos casos la totalidad de los dientes comprometidos. Esta nosología comprende un grupo heterogéneo de patologías de causas no determinadas. El objetivo de este trabajo es presentar un caso clínico de una paciente de 13 años con FGI Unilateral, su diagnóstico, tratamiento y seguimiento durante cuatro años. Presenta al examen clínico intraoral, agrandamiento anormal de su encía tanto superior como inferior, afectando solamente los hemiarcos del sector izquierdo. A la palpación es indolora y de consistencia fibrosa. No se encontraron factores locales que justifiquen dicho aumento. El examen físico elimina la posibilidad de otras patologías asociadas, no refiriendo recibir medicaciones inmunosupresivas, antiepilépticos o antihipertensivas. No tiene antecedentes familiares. La paciente fue sometida a extirpación quirúrgica del tejido hiperplasiado y el material obtenido enviado a estudio histopatológico. Después del tratamiento quirúrgico y una buena higiene oral con exámenes de control efectuados durante cuatro años no se observó recurrencia. A pesar de ser una patología poco frecuente el odontólogo debe conocer la fisiopatología y comprender que el manejo de ésta enfermedad es a través de un equipo multidisciplinario. El diagnóstico precoz y el tratamiento oportuno logran la recuperación psicológica, estética y funcional de los pacientes.
Gingival fibromatosis is a rare disease characterized by progressive enlargement of the gingiva caused by an increase in submucosal connective tissue. The enlargement may potentially cover the exposed tooth surfaces. Idiopathic gingival fibromatosis (IGF) is a heterogeneous group of disorders with no definite cause. The aim of this study is to present a 13-year-old female patient with unusual clinical forms of Unilateral FGI with a complete analysis of the features of the clinical diagnosis, treatment and follow-up for four years. Intraoral examination revealed severe gingival overgrowth involving both the upper arch and the lower arch, affecting on the left side. The right side of the mouth was unaffected. There was no significant pain. The lesion was diffuse, firm and fibrotic. Her medical and family history was also non-contributory. The patient was not receiving any antiepileptic, antihypertensive, or immunosuppressive medications that could contribute to the gingival enlargement. Histopathological examination showed hyperparakeratinized stratified squamous epithelium, presence of a thickened acanthotic epithelium and focal hyperplasia. Underlying connective tissue stroma was collagenous with numerous lymphoplasmacytic infiltrate. Unusual findings include the presence of calcified particles. Bevel gingivectomy was taken to remove gingival overgrowth. This case is thus a rare and atypical presentation of gingival fibromatosis. The patient was advised to maintain good oral hygiene to minimize the effect of inflammation on fibroblasts. In our case, even after four years of follow-up, no recurrence of gingival overgrowth was observed. Unilateral IGF is a relatively rare condition with poorly understood etiopathogenesis and recurrence rates. The cases should be treated with a multidisciplinary management. Treatment appreciably improved the patient's psychological, aesthetics and masticatory competence.
Subject(s)
Humans , Female , Adolescent , Fibromatosis, Gingival/diagnosis , Gingivectomy , Gingivoplasty , Radiography, Panoramic , Tomography, X-Ray Computed , Fibromatosis, Gingival/surgery , MalocclusionABSTRACT
Nonsyndromic hereditary gingival fibromatosis ( HGF) was a rare hereditary condition characterized by a progressive increase in gingival tissue , simultaneously with hypertrichosis and mental retardation.The patients often had troubles with mastication , appearance and pronunciation.The measure include surgical therapy.One case of HGF was reported and its relevant literature reviewed.
ABSTRACT
Asociada a factores genéticos, que se caracterizada por aumento en el tamaño del tejido gingival, el cual genera dificultades emocionales, estéticas y funcionales. En el presente artículo se reporta un caso de una paciente femenina de 13 años con aumento generalizado en el volumen de la encía, que cubre casi todos los dientes, la historia familiar fue muy importante para el diagnóstico de fibromatosis gingival hereditaria, ya que la madre y un hermano presentaron la misma manifestación.
Hereditary gingival fibromatosis is a rare disorder, associated with genetic factors, characterized by various degrees of attached gingival overgrowth, which generates emotional, aesthetic and functional disorders. This article reports the case of a 13-year-old female who presented a generalized severe gingival overgrowth, involving the maxillary and mandibular arches and covering almost the whole dentition. The family history was very important for the diagnosis of hereditary gingival fibromatosis, as the mother and a brother had the same disorder.
Subject(s)
Female , Fibromatosis, Gingival/surgery , Fibromatosis, Gingival/diagnosis , Fibromatosis, Gingival/genetics , Gingivectomy , Treatment OutcomeABSTRACT
La fibromatosis gingival es una deformidad desarrollada de baja prevalencia. Las características clínicas de la FG incluyen tejidos gingivales hiperplásicos de consistencia firme y nodular, presentándose en forma generalizada o localizada. Las características histológicas de la FG incluyen principalmente tejido conectivo con un denso infiltrado rico en fibras de colágeno y un epitelio denso con papilas epiteliales largas. Se presenta un reporte de caso de un paciente masculino de 12 años referido para su tratamiento al servicio de Periodoncia e Implantes dentales de la Clínica Estomatológica Central de la Universidad Peruana Cayetano Heredia.
Gingival fibromatosis is a developed deformity with low prevalence. The clinical features of FG include hyperplastic gingival tissues usually firm and nodular, occurring in a generalized or localized form. The histologic features of FG mainly include connective tissue with a dense infiltrate rich in collagen fibers and dense epithelium with epithelial papillae long. This is a case report of a male patient of 12 years referred for treatment to a Periodontics and Implants Service of the Central Dental Clinic of the Cayetano Heredia Peruvian University.