Research on the effect of contrast Shimadzu CL8000 Hitachi 7180 automatic biochemical analyzer cleaning / 中国医学装备

Objective:To me affiliated hospitals are currently using Shimadzu CL8000 Hitachi 7180 automatic biochemical analyzer comparison study on Shimadzu CL8000 Hitachi 7180 automatic biochemical analyzer cleaning effect for clinical obtain accurate test results provide a reliable basis. Methods:Patients with the same blood samples TG, TBA testing, using different instruments, different sequence of tests in order to determine Hitachi 7180 automatic biochemical analyzer and Shimadzu CL8000 automatic biochemical analyzer test results whether they carry the previous reagents, according to the detection results to determine two kinds of automatic biochemical analyzer after cleaning effect. Results:A group of TBA measurements were significantly higher than in group B, C group, D group(x2=4.091, P<0.05), comparing the results with statistical significance;B group, C group, D group compared TBA measurements no significant difference, the difference was not statistically significant. Conclusion:Shimadzu CL8000 automatic biochemical analyzer cleaning better than Hitachi 7180 automatic biochemical analyzer, its stable performance, excellent cleaning effect, clinicians can provide accurate diagnosis and treatment basis, improve patient outcomes, quality of life and protect their life safety, may be of clinical use.

Performance Evaluation of the Roche-Hitachi cobas 8000 c702 Chemistry Autoanalyzer

BACKGROUND: Optimal operational efficiency requires specific technical solutions such as open, flexible, and adaptable space, suitable equipment requirements, and laboratory instrumentation that combine excellent analytical performance with a capacity for testing large panels in a high throughput manner, under rapid turnaround times. Thus, the aim of this study was to assess the analytical performance of the novel Roche-Hitachi cobas 8000 c702 Chemistry Autoanalyzer. METHODS: Precision, linearity, carry over, detection limits, and comparison studies were performed with 31 routine clinical chemistry tests according to the CLSI guidelines. Commercial quality chemistry control material (Lyphochek, Bio-Rad, USA) and patient sera were used as the test specimens. Unicel DxC instrument (Beckman Coulter, USA) was used as a control analyzer to evaluate the correlation. RESULTS: The total coefficients of variations (CVs) of almost all the analytes were between 0.4 and 4.1%, except for CO2 and ammonia. Excellent linearities were observed in the performance ranges used (r>0.99, slope, 0.961-1.048). Correlations with analogous tests ran on the Unicel DxC instrument were good, correlation coefficients ranging between 0.921 and 1.000. The carryover ranged from -0.216 to 0.481%. CONCLUSIONS: The Roche-Hitachi cobas 8000 c702 Chemistry Autoanalyzer showed satisfactory precision, linearity, carry over, detection limits, and high throughput capacity. The instrument performance correlated well with the Unicel DxC analyzer. We conclude that the balance of elevated throughput and optimal analytical performance should make Roche-Hitachi cobas c702 Chemistry Autoanalyzer suitable for very large clinical laboratories.

Analytical Performance of Wako and Sekisui Clinical Chemistry Assays on Hitachi LABOSPECT 008

BACKGROUND: We evaluated the analytical performance of Wako assays for albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), complement C3 and C4, calcium, creatine kinase (CK), C-reactive protein (CRP), direct bilirubin (DBIL), iron, gamma-glutamyl transferase (GGT), HDL cholesterol (HDLC), inorganic phosphorus (IP), LDL cholesterol (LDLC), total bilirubin (TBIL), total protein (TP), and uric acid (UA), as well as the performance of Sekisui assays for albumin, BUN, calcium, CRP, HDLC, IP, LDLC, TP, and UA by using Hitachi LABOSPECT 008 (Hitachi High-Tech Co., Japan). METHODS: Liquid Assayed Multiqual Control (Bio-Rad Laboratories, USA) and pooled patients' sera were analyzed for 20 days. Wako linearity material (Wako Pure Chemical Industries, Ltd., Japan) and Sysmex Interference Check A Plus kit (Sysmex Co., Japan) were used to test linearity and interference, respectively. Concentrations of the target analytes were measured using Hitachi LABOSPECT 008 in 100 residual patient specimens and compared to those in Pureauto S series reagent (Sekisui Medical, Japan), which were measured using Hitachi 7600 (Hitachi High-Tech Co., Japan). RESULTS: Total coefficients of variation (CVs) for the tested analytes were 0.91-9.26% in Wako and 1.04-7.46% in Sekisui assays. Linearity was demonstrated up to the highest concentration within the analytical range in all the assays except for Wako albumin and Sekisui TP. Wako and Sekisui albumin, BUN, CRP, HDLC, and LDLC assays, and in Wako C3, C4, calcium, and UA assays showed no interference with the test concentrations used. All the tested assays, except for Wako AST, LDLC, and TP, and Sekisui calcium and TP, demonstrated comparability with comparative method for at least one medical decision level. CONCLUSIONS: Our study results showed that the analytical performances of Wako and Sekisui chemistry assays evaluated using Hitachi LABOSPECT 008 had appropriate analytical performance for clinical use.

Performance Evaluation of the Hitachi 7600-110 Chemistry Autoanalyzer / 대한임상병리학회지

BACKGROUND: Hitachi 7600-110 (Hitachi, Tokyo, Japan) is an automated chemistry analyzer introduced in 1999. It consists of one dispensing type plus one pipetting type module and one electrolyte analyzer. We evaluated the performance of the analyzer in order to access the utility of the Hitachi 7600-110 autoanalyzer for the efficiency of routine chemistry work. METHODS: Within-day and between-day precision, accuracy, linearity, and recovery rates for albumin, ALP, ALT, AST, BUN, Ca, cholesterol, creatinine, r-GT, glucose, phosphorus, total bilirubin, TG, total protein, uric acid, CK, direct bilirubin, Fe, HDL-cholesterol, LD, Mg, Cl, K, and Na (24 items) were evaluated. Commercialized quality control material, Lyphochek (Bio-Rad, CA, USA) and patient sera for test specimens were used. Vitros 750 (Johnson & Johnson, Rochester, USA) was used as a control analyzer to evaluate the correlation. RESULTS: The within-day coefficients of variations (CVs) of almost all items were less than 3.0% except for direct bilirubin (7.71%), Mg (6.65%), and Fe (5.83%). The between-day CVs of almost all items were less than 5% except the direct bilirubin (13.16%). All items showed good linearity in the performance range (r>0.99, slope, 0.97-1.0). The results of ALT, AST, BUN, creatinine, glucose, CK, LD, Cl, K, and Na between Hitachi 7600-110 and the Vitros 750 revealed good correlation (r> or = 0.975) except Na and Cl. Hitachi data of Na and Cl showed significantly lower results (P<0.05) than did the Vitros 750 data. The recovery rates for BUN, creatinine, glucose, and uric acid were in the range of 100.00 to 101.78%. CONCLUSIONS: Hitachi 7600-110 showed acceptable performance in the "within-day" and "between-day" precision, linearity, and accuracy. The Hitachi 7600-110 that combines dispensing and pipetting modules can improve the speed and the efficiency of the workflow and can minimize the reagent consumption and the cost of system management. Therefore, it can be used both in large laboratories in general hospitals with many examinations and in small laboratories with relatively small numbers of cases.

Evaluation of Hitachi 7600-110(R) for Quantitative Analysis of C-Reactive Protein / 대한임상병리학회지

BACKGROUND: The C-reactive protein(CRP) is one of the "acute phase" proteins and it is known to be the most sensitive indicator of the inflammatory and/or necrotic process. Traditional methods for measuring CRP are capillary precipitation assay and latex agglutination assay. However, these methods have low sensitivity and provide only qualitative results. Recently the development of specific and very sensitive assays for CRP using highly specific monoclonal antibodies for CRP have done, including radioimmunoassay, nephelometric assay(NA), and turbidimetric immunoassay(TIA). We evaluated the Hitachi 7600-110(R)(Hitachi Co., Japan) using TIA in the measurement of CRP and compared its results to those of the the LX-M(R)(Eiken Chemical Co., Japan) using NA in order to replace the Hitachi 7600-110(R) for quantitative analysis of CRP. METHODS: CRP were measured by the Hitachi 7600-110(R) using TIA and the LX-M(R) using NA in the sera from 106 patients. The relationship between results of Hitachi 7600-110(R) and LX-M(R). By performing 20 repetitive assays at three levels of CRP control serum and pooled sera, within-run, within-day, and between-day precision of the Hitachi 7600-110(R) were established. RESULTS: When the CRP value of 4.60 +/- 5.65 mg/dL by the Hitachi 7600-110(R) was compared with that of 3.71 +/- 4.32 mg/dL by the LX-M(R), coefficients of correlation of 0.994 was obtained. The regression equation was Y(Hitachi 7600-110(R)) = 1.298 X(LX-M(R)) - 0.211(r=0.994, n=106). CVs of CRP measured by Hitachi 7600-110(R) were 5.45% at 0.82 mg/dL, 1.32% at 2.39 mg/dL, and 2.37% at 4.62 mg/dL. The precision was excellent in each group. The linearity was acceptable, and sample to sample carry-over was 0.8%. CONCLUSIONS: The Hitachi 7600-110(R) using TIA, compared with the LX-M(R) using NA, showed good coefficient of correlation and excellent precision. Therefore the Hitachi 7600-110(R) can replace the LX-M for quantitative analysis of CRP.

Study on repacking of HITACHI SX-YB2 X-ray photography system / 医疗卫生装备

The new general photography system is composed of overhang of SX-YB2 departed from the mainframe of HITACHI Digital Fluoroscpic(model 110XF),topmanagement system of FSK302-1 and FSB302-1 and leveled adiogaphy system of F78-III.The filament heater circuit,rotating anode startup and running circui and X-ray produce circuit are mainly changed,and some circuits in power and filament heat are added.

Defect and resolvent of HITACHI 7080 biochemical analyzer / 医疗卫生装备

This paper presents the configuration defect of HITACHI 7080 biochemical analyzer and the trouble from it.The resolvent is also put forward.