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BACKGROUND: A key challenge for manufacturers of pro-health food containing active probiotic microorganisms is to develop a product with attractive sensory features along with maintenance of declared number of microorganisms during storage and transfer by alimentary tract. RESULTS: The highest concentration of polyphenols was observed in snacks without an additive of probiotics as well as those with an additive of L. rhamnosus and B. animalis bacteria and concentration of these compounds increased by 9.5% during six months of storage. None of the products distinguished itself in the sensorial assessment although each was assessed positively. The number of microorganisms was stable and comparatively high during six months of storage at a room temperature and in cooling conditions (108 cfu/g). In the digestion model, an influence of aggressive digestion conditions was examined in the alimentary tract on the number of microorganisms, which allowed to arrange strains from the most resistant (S. boulardii) to the most sensitive (B. breve). It must be noted that currently on the market there is no available snack containing probiotic yeast as well as there is no literature data on works on such formulation of food. CONCLUSIONS: In the newly developed snack made of chocolate, in which sugar has been replaced with maltitol, a raw material was added in the form of raspberry, prebiotic in the form of inulin and a strain of probiotic bacteria, including the unprecedented so far S. boulardii, which stands a high chance to occupy a good place on the market of functional food.
Subject(s)
Probiotics , Functional Food , Chocolate/microbiology , Sugar Alcohols , Temperature , Whole Foods , Digestion , Food Storage , Prebiotics , Synbiotics , Polyphenols , Snacks , Rubus , Maltose/analogs & derivativesABSTRACT
Objective:To detect 11 kinds of illegally added chemicals in anti-fatigue health foods including sildenafil ,tadalafil, vardenafil , acetildenafil , homosildenafil , hydorxyhomosildenafil , norneosildenafil , aminotadalafil , pseudovardenafil , thioaildenafil and noracetildenafil.Methods:An HPLC-MS/MS method was used with LUNA C18(250 mm ×4.6 mm, 5μm)as the analysis column and triethylamine phosphate , acetonitrile and methanol as the mobile phase with gradient elution at the flow rate of 1ml.min-1 .An ESI+scan and an MS/MS mode were applied .The qualitative and quantitative analysis were carried out by HPLC-MS/MS.Results:Through the detection of 100 batches of samples , 85 batches were only found illegally added chemical substance sildenafil mainly at the concentration of 5-15 mg per granule .Conclusion:The method of HPLC-MS/MS can be used as a powerful screening tool for the rapid drug screening in basic level drug control laboratories to reduce chemical substances illegally added in anti -fatigue health foods .
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O conceito de segurança alimentar e nutricional, construído coletivamente no cenário brasileiro, apresenta-se como um elemento catalizador de importantes reflexões na área de Nutrição Social. Este texto tem como objetivo refletir sobre as formas e os indicadores de avaliação em segurança alimentar e nutricional no Brasil. Esta breve reflexão se debruça sobre os desafios dos especialistas e pesquisadores da área em questão para abarcar seus princípios interdisciplinares; além disso, espera motivar o interesse pela elaboração de novos indicadores de avaliação e de metodologias e instrumentos de coleta de informação mais abrangentes e sistêmicos. Julga-se importante promover a reflexão sobre as limitações das escalas de mensuração da (in)segurança alimentar e nutricional em apontar e abarcar as complementaridades entre a vivência dessa insegurança e os processos e agentes de produção do fenômeno. Ressalta-se como desejável a inclusão da leitura do processo saúde-doença e o cuidado das morbidades resultantes da insegurança alimentar e nutricional como questões a serem exploradas em futuros estudos dessa temática.
The concept of food security, collectively constructed in the Brazilian scenario, is considered an important element to promote reflections in the area of Social Nutrition. This article aims to reflect on the evaluation indicators for food and nutrition security in Brazil. This brief reflection focuses on the challenges of experts and researchers in food and nutritional security to embrace its interdisciplinary principles. One expects to motivate the interest in developing new indicators and evaluation methodologies and more comprehensive and systemic instruments to collect information about food insecurity. It is deemed important to promote reflection on the limitations of the scales of measurement of food and nutrition (in)security in pointing and covering the complementarities between the experience of such insecurity and the processes and agents that produce this phenomenon. Issues to be explored in future studies are the inclusion of understanding the health-disease process and the care of morbidity resulting from food and nutrition insecurity.
Subject(s)
Public Health , Whole FoodsABSTRACT
Objective: To establish an accurate method for the determination of nine chemical drugs (phentolamine mesylate, methyltestosterone, stanozolol, danazol, tadalafil, sildenafil citrate, aildenafil, vardenafil, and thioaildenafil) which were illegally added into the antifatigue health foods. Methods: The UPLC-MS/MS method was adopted. The samples were extracted with methanol by ultrasonic processing and separated on a Waters Acquity BEH-C18 (100 mm × 2.1 mm, 1.7 μm) column with 0.1% formic acid methanol (A) and 0.1% formic acid water (B) as the mobile phase by gradient elution (0-5 min, 50% A; 5-7 min, 50%-90% A; 7-9 min, 90%-100% A; 9-10 min, 100%-50% A) at a flow rate of 0.2 mL/min. The injection volume was 5 μL. The column temperature was 40 ℃. The positive-ion (ESI+) source and MRM mode were used to separate and quantitatively determine the chemicals. The obtained molecular ions, fragment ions, and retention time for MRM channels were used to identify the nine kinds of drugs by comparing with those of reference substances. The obtained peak areas were used to determine the accurate content of the nine chemicals in the antifatigue health foods. Results: A good resolution of the nine kinds of chemical drugs, including phentolamine mesylate, methyltestosterone, stanozolol, danazol, tadalafil, sildenafil citrate, aildenafil, vardenafil, and thioaildenafil, was obtained under this UPLC and MS/MS conditions. The limits of detection (LOD) and quantification (LOQ) were in the ranges of 0.1-0.3 ng/g and 0.3-0.9 ng/g. The standard addition recoveries were in the range of 88.4%-116.3%. There were 68 batches of antifatigue health foods, among which 41 batches were added with the chemicals with positive rate of 60.3%. The sildenafil citrate, tadalafil, aildenafil, and hioaildenafil were detected in samples. Conclusion: The method is simple, accurate, and has high sensitivity, which can be used for the qualitative and quantitative determination of illegally added chemical drugs in the antifatigue health foods.
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Introducción: las especies reactivas de oxígeno (ERO), afectan al organismo humano con patologías como las enfermedades cardiovasculares y las crónicas no transmisibles. La incidencia de éstas es menor si en la dieta diaria se incluye un alto consumo de frutos y hortalizas; por esta razón, es importante conocer sus propiedades fitoquímicas. Objetivo: determinar la capacidad antioxidante del jugo de gulupa (Passiflora edulis Sims) en poscosecha. Métodos: se cosecharon frutos en madurez fisiológica y se mantuvieron al ambiente (20 ºC y 70 % de HR) por 21 días, tiempo en el que se midió la actividad antioxidante con los métodos radical catiónico ABTS•+ y el poder antioxidante de reducción del Fe+3 (FRAP), el contenido de ácido ascórbico por HPLC y los carotenoides por espectrofotometría ultravioleta-visible (UV-Vis). Resultados: se apreció una tendencia ascendente en la actividad antioxidante a través del tiempo en poscosecha, con énfasis en el día 14, lo que conduce a manifestar que es la época recomendable para el consumo. El ácido ascórbico (vitamina C), se expresó de manera inestable, pero el aumento hacia el final del almacenamiento fue evidente, mientras que los carotenoides presentaron un incremento constante. Conclusiones: la actividad antioxidante del jugo de gulupa, puede estar dada por los contenidos de ácido ascórbico y carotenoides. Es importante la definición del tiempo de consumo después de la cosecha del fruto, para aprovechar al máximo su valor como alimento nutracéutico. Estos aspectos son útiles para fortalecer la posición de la gulupa en el mercado de exportación.
Introduction: reactive oxygen species (ROS) affect the human body with pathologies such as cardiovascular and chronic non-communicable diseases. The incidence of these diseases is lower when the daily diet includes a high intake of fruits and vegetables. This is the reason why it is important to be acquainted with their phytochemical properties. Objective: determine the antioxidant capacity of the juice of purple passion fruit (Passiflora edulis Sims) in the postharvest period. Methods: physiologically mature fruits were harvested and kept in the open (20 °C and 70 % RH) for 21 days. During that period, antioxidant activity was measured with ABTS•+ radical cation assay and Fe+3 ferric reducing ability of plasma (FRAP), whereas ascorbic acid content was determined by HPLC and carotenoids by ultraviolet-visible (UV-Vis) spectrophotometry. Results: antioxidant activity showed an upward trend during the postharvest period, reaching its peak on day 14. It is therefore advisable to consume the fruit around that day. Ascorbic acid (vitamin C) was expressed in an unstable manner, but increase was evident by the end of the storage period. Carotenoid content showed a steady increase. Conclusions: antioxidant activity of purple passion fruit juice may be due to the contents of ascorbic acid and carotenoids. It is important to define the most suitable time for consumption during the postharvest period, to obtain the maximum nutraceutical benefit. These notions are useful to strengthen the position of purple passion fruit in the export market.
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<b>Objective: </b>Recently, use of health foods and supplements, as well as the amount of information available about them, has been steadily increasing. Therefore, a noticeable increase in adverse drug reactions caused by health foods and supplements has also been seen. The purpose of this study was to clarify the current status and backgrounds of patients with health food- or supplement-related adverse health effects.<br><b>Methods: </b>We selected the cases of health food- or supplement-related adverse health effects from the Case Reports of Adverse Drug Reactions and Poisoning Information System (CARPIS) database, which contains over 57,000 case reports of adverse drug reactions. We investigated the background, suspected products and adverse events in each case and conducted univariate logistic regression analysis to determine significance.<br><b>Results: </b>We obtained a total of 327 cases consisting of 103 causative products. Women comprised 66% of study subjects and had a significant association with dietary supplements. Patients with a history of liver disease had a significant association with liver damage caused by “Ukon,” a drink made from turmeric root and sold as an anti-hangover remedy in Japan.<br><b>Conclusion: </b>The causative products had several unique features. This information should be utilized to prevent health food- and supplement-related adverse health effects in the future.
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OBJECTIVE: To establish the RP-HPLC specific chromatogram of Dendrobium officinale capsules for the quality control. METHODS: An Ultimate C18 column (4.6 mm × 250 mm, 5 μm) maintained at 30°C was used for all analysis. Chromatographic separation was carried out using gradient elution of methanol and 0.2% phosphoric acid aqueous solution at a flow rate of 1.0 mL · min. The detection wavelength was set at 280 nm. The similarity evaluation system for chromatographic fingerprint of TCM (National Pharmacopoeia Committee) was adopted to construct the specific chromatogram. RESULTS: The HPLC specific chromatogram of Dendrobium officinale capsules was constructed with four common specific peaks with naringenin peak as the reference. CONCLUSION: The method shows good precision and repeatability. It can be used for the quality control of Dendrobium officinale capsules and can be taken as a reference for the identification and quality control of other Dendrobium officinale-related health foods.
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OBJECTIVE: To review the development of Dendrobium officinale Kimura et Milated health foods. METHODS: Through the database of Slate Food and Drug Administration and State Intellectual Property Office website, all health foods mainly composed of D. officinale and related patents were listed and analyzed. RESULTS AND CONCLUSION: D. officinale related health foods can be further developed by continuous improvement their health of functions, formulation composition and dosage form. Combined with novel foods development, the function and form of Dendrobium officinale related health foods will be diversified and even enter the international market.
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This study examined the effect of self-perception of health and related factors of flood life and disease on health floods intakes among the middle aged(150 men and 159 women) in the Jeonbuk region. The health foods were classified into 4 groups including Chinese medicine(CM), toner foods(TF), nutritional supplements(NS), and other manufactured health foods supplements(MHFS). Differences of BMI and self-perception for body shape was that overweight was 30% in men and 24.5% in women on BMI, but conversely was 21.3% in men and 43.4% in women on self-perception for body shape. Men thought themselves more than normal weight, but women thought themselves less than normal weight for the criteria of normal weight. Consumption of CM was high in the overweight group on BMI and was a low in the overweight group on self-perception for bodyshape Men thought themselves better than women and those in their 40's thought better than those in their 50's on self perception of health status, and women were better than men on self-perception of food habits. The difference of health foods intakes according to the self-perception of health status and food habits was not significant. The points of food habits, food attitude and nutrition knowledge were 11.21 +/- 2.43, 68.18 +/- 15.56 and 15.53 +/- 1.59 in women and 10.49 +/- 2.71, 67.53 +/- 14.41, and 15.11 +/- 1.79 in men respectively. The points of all were higher for women than for men. Consumption of CM (p<0.01) and TF(p<0.01) were a low in groups that scored high points on nutrition knowledge. The points of climacteric symptoms were that men were 48.36 +/- 6.30 and woman were 46.43 +/- 6.70. Men thought themselves in good condition more than women(p<0.01), and those in their 40's thought themselves in good condition as opposed to those in their 50's in men(p<0.05). Consumption of TF and NS were high in the low points group on climacteric symptoms(p<0.01). Women were higher than men on morbidity, but men were more than women on cases of liver disease(p<0.01). Consumption of CM was high in the liver disease group(p<0.05), MHFS was high in the kidney disease group(p<0.05), TF and NS were hgih in the bone disease group(p<0.05) and NS was hgih in the endocrine disease group(p<0.05). People in their 40's were higher than those in their 50's in men on morbidity of cold(p<0.05), women were higher than men by about 2 times on constipation (p<0.01), those in their 40's were higher than those in their 50's in mein on gastritis(p<0.05). Consumption of NS was highest for those with diseases in respiratory organs and gastrointestinal tracts. This study suggests that nutritional education for the right recognition of self-perception of health status and food habits, and nutrition knowledge are needed to select for health floods. Consumption of health foods was different according to kinds of diseases. Thus, recognition of etiology, symptoms and dietetics of diseases is needed to select adequate health foods for diseases in middle age.
Subject(s)
Female , Humans , Male , Middle Aged , Asian People , Bone Diseases , Climacteric , Constipation , Dietetics , Education , Endocrine System Diseases , Floods , Feeding Behavior , Gastrointestinal Tract , Food, Organic , Kidney Diseases , Liver , Liver Diseases , Overweight , Self ConceptABSTRACT
This study examined health foods intakes and related variables among the middle aged(150 men and 159 women) in the Jeonbuk region. Health foods were classified into 4 groups including Chinese medicine(CM), toner foods(TF), vitamin or mineral supplements(VMS), and other manufactured health food supplements(MHFS). The number of people taking health foods were higher for those in their 50's than in their 40's. The consumption rate of TF in men was the highest among health foods, this result had significance. The reasons for taking health foods were recovery from fatigue, supplement of nutrients and making smooth body activity in general, but TF was used to increase of vigor. The consumption rate of health foods was a little different according to social-economic factors, namely, the consumption rate of CM was higher in people in rural than urban areas, those who graduated from middle school than university, blue color & self-employed as opposed to housewives and service workers, low level income than high level income, and Buddhism and no religion than Christian. The consumption rate had a correlation with the habits of smoking, alcohol drinking and exercise ; namely, the consumption rate of CM was higher than VMS and MHFS on smokers and alcohol drinkers. The more the frequency of exercise, the higher the consumption rate of TF, but the duration of the exercise was not correlated. This study suggests that middle aged people need nutritional education for the right recognition and selection of health foods and to consider the nature of each type of health foods.