Clinical Diagnostic Application of Serum Cholinesterase

Serum cholinesterase and other commonly employed function tests were determined in 12 patients with nephrotic syndrome, 17 patients with infectious hepatitis and 7 patients with acute glomerulonephritis who were available for se5rial studies the evaluation of which was helpful in diagnosis, management and prognosis of various disease. The results were as follows. 1) Serum cholinesterase activity in patients with nephrotic syndrome was much higher than normal. Thereafter the activity progressively turned into the normal. Value associated with improvement of the values of other function tests and clinical courses in case which responded positively to treatment. 2) In patients with infectious hepatitis serum cholinesterase was lower than the normal value but the steadily rose from low to normal value according to improvement of clinical courses. In two patients with postnecrotic cirrhosis and toxic hepatitis the activity was much lower than normal but other function tests showed normal range. 3) Serum cholinesterase in patients with glomerulonephritis showed atypical charges during clinical courses.

A Study of Serum Ferritin Levels in Patients with Acute Infectious Hepatitis

Serum ferritin, iron, and total iron binding capacity were measured in 47 patients who were admitted to Hanyang University Hospital under the diagnosis of acute infectious hepatitis(excluding HBsAg positive patients) from September 1980 to March 1981. At the same time, serum transminase were estimated as indicator of liver function. Then we evaluated the relationship between serum ferritin, iron, and iron binding capacity and transaminase. The results were as followings: 1. Among 47 cases, 25 cases were male and 22 cases were female. Age distribution was from 1 year and 10 months to 14 years old. 2. Serum transaminase levels, GOT were from 51 unit to 1,010 unit and mean value was 644.8+/-315.7unit, and GPT were from 139 unit to 825 unit and mean value was 662.3+/-231.6 unit. 3. Serum iron levels were from 33microgram/dl to 264microgram/dl and mean value was 103.6+/-42.7microgram/dl, total iron binding capacities were from 267microgram/dl to 588microgram/dl, and mean value was 393.5+/-80.6microgram/dl. Serum ferritin levels were from 12ng/ml to 1,420ng/ml and mean value was 184.3+/-251.7ng/ml. 4. There was no correlation between serum iron and serum transaminase. 5. There was no correlation between total iron binding capacity and serum transaminase. 6. There was no correlation between serum ferritin and serum transaminase.