ABSTRACT
OBJECTIVE:To investigate the influence of health education prescription on the reduction of intravenous dripping leakage in obstetrics and gynecology department of our hospital. METHODS:Totally 300 inpatients selected from obstetrics and gy-necology department of our hospital Jun.-Nov. 2015 were divided into observation group and control group according to random number table,with 150 cases in each group. Control group received health education of daily operation during intravenous dripping. In observation group,intravenous dripping treatment card came with a health education prescription of intravenous dripping,which facilitate the patients and families to consult;the nurses carried out health education for patients every day during dripping in accor-dance to the prescriptions;clinical pharmacists accompanied resident physicians to make patient round and conducted random health education inspection. Awareness rate of health education prescription content,satisfactory rate of treatment,dripping rate of Magne-sium sulfate injection and Cefazolin sodium for injection,the incidence of ADR were compared between 2 groups. The intravenous dripping leakage were observed in 2 groups. RESULTS:The awareness rate of health education prescription content and satisfactory rate of treatment were 94.0% and 96.0% in observation group,which was significantly higher than 70.35% and 85.75% of control group,with statistical significance (P<0.05). The dripping rate of Magnesium sulfate injection <40 drops/min accounted for 97.6% in observation group,which was significantly higher than 91.6% of control group;the incidence of ADR was 0.3% in ob-servation group,which was significantly lower than 1.3% of control group. The dripping rate of Cefazolin sodium for injection <60 drops/min accounted for 92.3%,which was significantly higher than 85.0% of control group;the incidence of ADR was 0.4%in observation group,which was significantly lower than 1.0% of control group,with statistical significance(P<0.05). The intra-venous dripping leakage rate was 5.5%in observation group,which was significantly lower than 9.5%of control group,with statis-tical significance(P<0.05). CONCLUSIONS:Health education prescription can significantly improve satisfactory degree of treat-ment and reduce ADR and leakage during intravenous dripping
ABSTRACT
OBJECTIVE:To investigate the optimal administration route of ambroxol in the treatment of pediatric respiratory disease. METHODS:Totally 120 children with respiratory disease in pediatric department of our hospital during Jun. 2014-Jun. 2016 were divided into intravenous dripping group and atomization inhalation group according to even and odd-numbered admission order,with 60 cases in each group. Intravenous drip group was given Ambroxol hydrochloride injection 7.5 mg dissolved in 5%glucose solution 50 mL,ivgtt,bid;aerosol inhalation group was given aerosol inhalation of Ambroxol hydrochloride injection 7.5 mg,for 15 min each time,bid. The two groups were treated with 7 d. Clinical efficacies,p(O2)and p(CO2)level,the times of sputum absorption,clinical indexes and the occurrence of ADR were compared between 2 groups. RESULTS:Total response rate of atomization inhalation group(96.67%)was significantly higher than intravenous dripping group(78.33%);p(O2)level was sig-nificantly higher than intravenous dripping group,while the times of sputum absorption,fever disappearance time,asthma disap-pearance time,oxygen therapy time,pulmonary rales disappearance time,cough disappearance time and average hospitalization time were significantly less or shorter intravenous dripping group,with statistical significance (P0.05). CONCLUSIONS:Ambroxol is effective in the treatment of pediatric respiratory disease,and clinical efficacy of atomization inhalation is better than intravenous drop.
ABSTRACT
Objective To investigate the clinical efficacy and safety of reteplase(rPA)adminis-tration in treating acute deep venous thrombosis(ADVT)of lower extremity.Methods A total of 1 87 pa-tients with ADVT were randomly divided into two groups,with 85 patients in rapid intravenous dripping group and 1 02 patients in 24-hour venouspumping group.Their effects on limb swelling,thrombolysis,and complicationswere compared for analysis.Results The differences in the curative effectsof reducingswell-ingand thrombolysis effect between the two groups werenot significant(P >0.05).Thethrombolysis time in the 24-hour venouspumping group was shorter than that of the rapid intravenous dripping group [(4.76 ± 1 .56)days vs(6.56 ±0.83)days,P <0.05],indicating 24-hour venouspumping was more effective than rapid intravenous dripping.Complication incidence in the 24-hour venouspumping group was less than that of the rapid intravenous dripping group(3.90% vs 1 7.6%,P <0.05).Conclusion rPA is a goodvenous thrombolytic agentwith rapid effect in treating ADVT.The 24-hour venouspumping was more effective and safe than the rapid intravenous dripping.