ABSTRACT
Classical prescription is long-lasting which is characterized by simple composition and obvious curative effect. It is popular over China and welcomed by many people. Japanese Kampo medicine and traditional Chinese medicine originated from the same resource but flowed into two branches. Some classical prescription experts are mostly influenced by Japanese Kampo medicine, emphasizing the correspondence between prescriptions and syndromes, physical identification and abdominal diagnosis, which have become the research direction of most classical prescription scholars. Traditional Chinese medicine and Japanese Kampo medicine differ in the dialectical system, application form, dose and dosage form of classical prescription. It is important to have a clear insight of the development status of classical prescription in Chinese medicine and that of Japanese Kampo medicine, understand the differences between them and make full use of advantages and avoid disadvantages. It can provide ideas for the correct development path of classical prescription and reference for the research of preparation of classical prescription in China.
ABSTRACT
This paper introduces the general information of Japanese Kampo preparations, including the catalogue, classification, approval, production and so on, and summarizes their quality characteristics on medicinal materials, formulation, productive process, and quality control. It is suggested that classical representative prescriptions should be selected in combination with clinical application, and the research of classical prescription preparations should follow the guidance of traditional Chinese medicine (TCM) theories and the characteristics of clinical application of TCM, attach important to the research after listed, and strengthen studies on the quality control. Moreover, the reassessment of post-marketed "classical representative famous prescription" preparations should be paid more attention to. The research of new Chinese materia medica (CMM) should strengthen quality control of medicinal materials/pieces source, and new CMM compound preparation research should base on the history of human use. Quality control study of new CMM should base on "quality by design" ideas and concepts, and strengthen process control research and quality standard research.
ABSTRACT
To investigate the difficulties of taking Japanese traditional (Kampo) medicines, questionnaires were filled out by patients under 19 years old or their families. Forty-six questionnaires were valid for analysis. The mean age of the patients was 9.7 &qlusmn; 5.3 years old (2 to 19 years old) and the percentage of male patients was high (65%). They took extract granules (n = 40) or decoction (n = 6) and most of the patients (n = 38, 83%) took medicines twice a day. Though 69% of patients under 5 years old needed direct assistance from their family to take medicines, none of over 6 years of age needed any help except to dissolve medicines in hot water, while notably 77% of the patients over 13 years old took their medicines un-aided. It was found that patients' families gave them the concrete explanations on the necessity of their medicines regardless of patients' age, so it is important for pharmacist to guide not only families but also patients themselves. Furthermore, pharmacists should understand the taste and the constituent crude drugs of Kampo medicines to improve patients' adherence in taking medicines.
ABSTRACT
To investigate the difficulties of taking Japanese traditional (Kampo) medicines, questionnaires were filled out by patients under 19 years old or their families.Forty-six questionnaires were valid for analysis. The mean age of the patients was 9.7 &qlusmn; 5.3 years old (2 to 19 years old) and the percentage of male patients was high (65%). They took extract granules (n = 40) or decoction (n = 6) and most of the patients (n = 38, 83%) took medicines twice a day. Though 69% of patients under 5 years old needed direct assistance from their family to take medicines, none of over 6 years of age needed any help except to dissolve medicines in hot water, while notably 77% of the patients over 13 years old took their medicines un-aided. It was found that patients' families gave them the concrete explanations on the necessity of their medicines regardless of patients' age, so it is important for pharmacist to guide not only families but also patients themselves. Furthermore, pharmacists should understand the taste and the constituent crude drugs of Kampo medicines to improve patients' adherence in taking medicines.
ABSTRACT
On the basis of summing up the relative works of Japanese journals,this article emphasized introducing the Japanese Kampo Medicine schools,the actuality of Japanese Kampo Medicine clinical researches and the outlook of the Kampo Medicine.This article aimed at making clinicians and researchers understand the form of Japanese Kampo Medichue and thinking method of Japanese Kampo Medicine school,hoping to provide reference for clinical treatment and research.
ABSTRACT
The historical circumstances about the application of the Japanese Kampo-medicine on the point of clinical view are the following that the original directions of the Chinese medical classics have been strictly adhered in China while the directions of those have been remarkably developed in Japan after the import. Now the Japanese Kampo-medecine are based upon these recent developments as well as the current pharmacological studies. Several clinical casereports are demonstrated who are treated with Daisaiko-to, Hachimijio-gan, and Hochuekki-to.<br>Finally the noteworthy opinions by Sensai Nagayo who laid the foundation of the medical system in modern Japan are quoted from his autobiography. Namely the really valuable new medicine should be established with the combination of both the western medicine and the Kampo-medicine.
ABSTRACT
Objective:To identify Huanglianjiedu Decoction preparation (Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae) made from different technics and Japanese Kampo with fingerprint chromatographic. Methods: The HPLC method was used, chromatography conditions were C 18V column, binary solvent-delivery gradient elution, diode-array detector, internal standard (paeoniflorin) were taken as the criteria for quality control. Results: The result showed that 15～16 characteristic peaks were common, but the new technic preparation and EtOH extract showed a specific characteristic peak. And significant deviation has been found from peak-height ratio of characteristic peaks to internal standard in various preparations, which were made from different technics or from different materials. Conclusion: The good reproducibility and stability are showed in experiment results. The HPLC fingerprint can be used for identifying this traditional Chinese medicine preparations which were made from different technics or from different materials.