Avaliação da dilatação cervical em simuladores de dilatação / Evaluación de la dilatación cervical en simuladores de dilatación / Cervical dilation assessment in dilation simulators

Resumo Objetivo Comparar o número de acertos dos estudantes na avaliação da dilatação cervical em simuladores de dilatação com e sem o uso de uma validação visual direta. Métodos Estudo transversal com 40 alunos de graduação em Obstetrícia de uma Universidade Pública de São Paulo, que avaliaram as dilatações cervicais em simuladores de dilatação às cegas, em três etapas: na primeira, estimaram as dilatações nos simuladores, na segunda, compararam sequencialmente os achados nos simuladores com uma ferramenta de validação visual direta usando a mão dominante e depois a mão não dominante, e na terceira etapa, compararam simultaneamente as estimativas encontradas nos simuladores com a validação visual direta com a mão dominante e não dominante. O desfecho foi o acerto da dilatação cervical nos simuladores de dilatação ou não acerto, com valor de p ≤ 0,05 considerado estatisticamente significativo. Resultados Foram analisadas 240 avaliações e computados os acertos dos estudantes relacionados a avaliação da dilatação cervical dos simuladores. Houve aumento da taxa de acerto de 47,1% com o uso da validação visual direta (OR= 4,689; IC95%: 2,601-8,452; p<0,001). Conclusão O uso de uma validação visual direta aumenta a probabilidade de acertos dos alunos na avaliação da dilatação cervical em simuladores de dilatação.

Resumen Objetivo Comparar el número de aciertos de los estudiantes en la evaluación de la dilatación cervical en simuladores de dilatación con y sin uso de una validación visual directa. Métodos Estudio transversal con 40 alumnos de la carrera de Obstetricia de una universidad pública de São Paulo, quienes evaluaron las dilataciones cervicales en simuladores de dilatación a ciegas, en tres etapas: en la primera, estimaron las dilataciones en los simuladores; en la segunda, compararon secuencialmente los resultados en los simuladores con una herramienta de validación visual directa usando la mano dominante y después la mano no dominante; y en la tercera etapa, compararon simultáneamente las estimativas encontradas en los simuladores con la validación visual directa con la mano dominante y no dominante. El criterio de valoración fue el acierto de la dilatación cervical en los simuladores de dilatación o el no acierto, con un valor de p ≤ 0,05 considerado estadísticamente significativo. Resultados Se analizaron 240 evaluaciones y se computaron los aciertos de los estudiantes relacionados con la evaluación de la dilatación cervical de los simuladores. Hubo un aumento del índice de acierto del 47,1 % con el uso de la validación visual directa (OR= 4,689; IC 95 %: 2,601-8,452; p<0,001). Conclusión El uso de una validación visual directa aumenta la probabilidad de aciertos de los alumnos en la evaluación de la dilatación cervical en simuladores de dilatación.

Abstract Objective To compare the number of hits of students in cervical dilation assessment in dilation simulators with and without the use of direct visual validation. Methods This is a cross-sectional study with 40 undergraduate obstetrics students from a public university in São Paulo, who assessed cervical dilatations in blind dilatation simulators, in three stages: in the first, they estimated dilations in the simulators; in the second, they sequentially compared the findings in simulators with a direct visual validation tool using the dominant hand and then the non-dominant hand; and in the third step, they simultaneously compared the estimates found in simulators with direct visual validation with the dominant and non-dominant hands. The outcome was the success of cervical dilation in dilation simulators or not, with a p-value ≤ 0.05 considered statistically significant. Results We analyzed 240 assessments and computed the hits of students related to cervical dilatation assessment of simulators. There was an increase in the hit rate of 47.1% with the use of direct visual validation (OR= 4.689; 95%CI: 2.601-8.452; p<0.001). Conclusion The use of direct visual validation increases the probability of hits by students in cervical dilation assessment in dilation simulators.

Duration of second stage of labor and its association with pregnancy outcome / 中华围产医学杂志

Objective:To analyze the duration of the second stage of labor without epidural anesthesia and its association with pregnancy outcome.Methods:This retrospective study involved 12 789 women who delivered without epidural anesthesia in the First Affiliated Hospital of Kunming Medical University from January 1, 2014 to December 31, 2017. These subjects were divided into primipara group (9 517 cases) and multipara group (3 272 cases). Demographic characteristics, maternal and neonatal outcomes and the duration of the second stage of labor were compared between the two groups using two independent samples t-test, Mann-Whitney U test and Chi-square test (Fisher's exact test). Differences in the maternal and neonatal outcomes were also analyzed among different subgroups in primiparae [length of second stage: <1 h group ( n=6 265), ≥1-2 h group ( n=2 305), ≥2-3 h group ( n=831) and ≥3 h group ( n=116)] and multiparae [length of second stage <1 h group ( n=3 144), ≥1-2 h group ( n=102) and ≥2 h group ( n=26)]. The association between second stage length and pregnancy outcomes was analyzed with Cramer's V. After adjusted for maternal age, gestational weeks at delivery, body mass index before pregnancy, complications during pregnancy and neonatal birth weight, the relationship between the duration of the second stage and adverse outcomes was analyzed by binary logistic regression analysis. Results:The 95 th percentile of the second-stage labor duration was 143 min for primiparae and 52 min for multiparae. The rates of vaginal delivery, forceps delivery, cesarean section in the second stage, episiotomy, third- or fourth-degree perineal laceration, postpartum hemorrhage, grade Ⅱ postpartum hemorrhage, transfusion, umbilical arterial blood gas pH<7.15 and transferring to neonatal intensive care unit (NICU) were all correlated with the duration of second stage in primiparae (Cramer's V values: 0.22, 0.23, 0.03, 0.22, 0.05, 0.10, 0.03, 0.03, 0.03 and 0.07, respectively, all P<0.05), and so did those of vaginal delivery, forceps delivery, episiotomy, postpartum hemorrhage, grade Ⅱ postpartum hemorrhage, transfusion and transferring to NICU in multiparae (Cramer's V values: 0.18, 0.19, 0.28, 0.14, 0.09, 0.13 and 0.06, respectively, all P<0.05). Logistic analysis showed that in primiparae, the duration of second stage >1 h was an independent risk factor for episiotomy, third- or fourth-degree perineum laceration, forceps delivery, postpartum hemorrhage, admission to NICU and umbilical arterial blood gas pH<7.15 [adjusted OR (95% CI): 2.080 (1.907-2.268), 1.773 (1.080-2.911), 1.625 (1.420-1.859), 1.365 (1.231- 1.514), 1.305 (1.165-1.462) and 1.246 (1.081-1.436), respectively], while second stage length >2 h was the independent risk factor for episiotomy, forceps delivery, third- or fourth-degree perineum laceration, postpartum hemorrhage, grade Ⅱ postpartum hemorrhage, blood transfusion, admission to NICU and umbilical arterial blood gas pH<7.15 [adjusted OR (95% CI): 4.844 (4.132-5.678), 4.223 (3.571-4.993), 3.289 (1.806-5.989), 1.952 (1.675-2.274), 1.781 (1.057-3.001), 1.654 (1.025-2.668), 1.682 (1.421-1.991) and 1.298 (1.039-1.620), respectively]. In multiparae, the length of second stage >1 h was an independent risk factor for episiotomy, blood transfusion, forceps delivery, postpartum hemorrhage and admission to NICU [adjusted OR (95% CI): 8.796 (5.717-13.534), 7.469 (2.874-19.411), 6.135 (3.217-11.699), 2.697 (1.624-4.477) and 1.814 (1.063-3.097), respectively], while the duration of second stage >2 h was the independent risk factor for episiotomy, third- or fourth-degree perineum laceration, blood transfusion, grade Ⅱ postpartum hemorrhage, forceps delivery and postpartum hemorrhage [adjusted OR (95% CI): 38.868 (14.948-101.063), 28.046 (2.780-282.490), 20.076 (5.384-74.866), 16.327 (3.406-78.274), 14.337 (5.351-38.411) and 9.036 (3.880-21.011), respectively]. Conclusions:The duration of the second stage of labor without epidural anesthesia is between that reported by Friedman and by Zhang. A prolonged second stage of labor may increase the risk of adverse pregnancy outcomes.

Changes of cardiac output during labor in healthy term pregnant women of reproductive age / 中华围产医学杂志

Objective:To assess the changes of cardiac output (CO)-related indices in healthy term reproductive age pregnant women during labor.Methods:A prospective longitudinal study was conducted, involving 208 pregnant women at term who were at an reproductive age and admitted to the labor ward of Tianjin Central Hospital of Obstetrics and Gynecology from October 2020 to March 2021. The internal diameter of the aortic root, velocity-time integral of aortic valve flow, and heart rate were obtained through transthoracic echocardiography during uterine contractions period and the intervals between contractions in the latent phase, active phase, and the second stage of labor, as well as at one hour after delivery. Stroke volume (SV), CO, and cardiac index (CI) were then calculated. Comparisons among groups were performed using t-test, analysis of variance, or Wilcoxon test. CO-related indices during contractions periods and intervals between contractions were compared using paired t-test, those in each stage of labor using repeated measurement analysis of variance. Results:(1) CO-related indices in contractions periods vs intervals between contractions during labor: In the latent phase, maternal heart rate [79(72 -84) vs 76(70 -85) bpm, Z=－2.03, P<0.05], SV [(77.9±13.4) vs (71.1±12.8) ml, t=－13.98, P<0.05], CO [(6.1 ±1.2) vs (5.5 ±1.1) L/min, t=－14.19, P<0.05], and CI [(3.5 ±0.7) vs (3.1 ±0.6) L/(min·m 2), t=－14.29, P<0.05] during contractions were higher than those during the intervals. These parameters during contractions in the active phase and the second stage of labor were all higher than those during the intervals in the same stage (all P<0.05). (2) CO-related indices in each period of labor: Heart rate, CO, and CI during the intervals between contractions gradually increased along with labor progression and reached the peak at the second stage followed by a decrease at one hour after delivery, and a similar trend was also observed for these parameters during contractions in the whole labor (all P<0.05). No significant changes in the maternal SV during intervals between contractions were observed during the labor( P=0.366), while the figure during contractions showed a decreased trend along with the course of labor and declined to a nadir in the second stage (all P<0.05). Conclusions:Cardiac output related indices change significantly in healthy term reproductive age pregnant women during labor, especially in the second stage of labor. Therefore, correct monitoring and management of hemodynamic changes during labor are of great importance in the stability of cardiovascular function throughout labor.

Application effects of unprotected perineal delivery technique in low-risk nulliparous women during natural delivery / 中国基层医药

Objective:To investigate the application effects of unprotected perineal delivery technique in low-risk nulliparous women during natural delivery.Methods:Seventy low-risk nulliparous women who delivered in January to December 2017 in Huaibei People's Hospital were included in this study. They were randomly assigned to undergo delivery with either conventional technology (control group, n = 35) or unprotected perineal delivery technique (observation group, n = 35). Lateral episiotomy rate, incidence of perineal tears, labor process time and Visual Analogue Scale score as well as the degree of postpartum perineal pain were compared between two groups. Results:Lateral episiotomy rate in the observation group was significantly lower than that in the control group [8.57% (3/35) vs. (45.71% (16/35), χ2 = 10.402, P < 0.001). The incidence rates of complete perineum, grade I perineal injury and grade II perineal injury in the observation group were 34.29% (12/35), 57.14% (20/35) and 8.57% (3/35), respectively, and those in the control group were 11.43% (4/35), 28.57% (10/35) and 60.00% (21/35) respectively ( χ2 = 4.732, 4.725, 18.324, all P < 0.05). The Visual Analogue Scale score in the observation group was significantly lower than that in the control group [(3.08 ± 0.42) points vs. (5.13 ± 0.58) points, t = 16.936, P < 0.001]. There were no significant differences in the time of first-stage, second-stage and third-stage labors between the two groups (all P > 0.05). Conclusion:Application of unprotected perineal delivery technique for low-risk primipara delivery can reduce maternal injury during delivery, which is worthy of application.

Uso de uterotônicos no terceiro período do parto em uma maternidade da Zona da Mata Mineira / Uso de uterotónicos en el tercer período de parto en una maternidad en la Región de Mata Mineira / Use of uterotonics in the third stage of labor in a maternity in the mata mineira area

RESUMO OBJETIVO: avaliar o uso de uterotônico em parturientes primíparas durante o terceiro período de trabalho de parto, segundo via de nascimento e fatores assistenciais associados, em uma maternidade de um município Zona da Mata Mineira. MÉTODO: estudo transversal, descritivo e analítico, com 222 mulheres. A coleta de dados ocorreu por meio de entrevistas. A análise descritiva foi realizada mediante frequências relativas e absolutas. O teste qui-quadrado de Pearson foi utilizado para identificar as diferenças estatísticas relacionadas ao uso do uterotônico, tendo em vista as características sociodemográficas e a assistência obstétrica. Modelos de regressão de Poisson foram utilizados para estimar as razões de prevalência bruta e ajustada. RESULTADO: mais de 80% das puérperas receberam uterotônico independentemente da via de administração. Após ajustes por características sociodemográficas, identificou-se que: não estar em trabalho de parto na internação; ter tido parto normal; amamentar na sala de parto; ter acompanhante na sala de parto; ter contato pele a pele; e receber massagem para extração da placenta foram condições associados ao uso do uterotônico intramuscular. Evidenciou-se que: ter sido submetida à cesariana; não amamentar na sala de parto; não receber contato pele a pele; e não ser submetida à massagem para extração da placenta associaram-se ao uso intravenoso. CONCLUSÃO: concluiu-se que fatores da assistência obstétrica estão associados à aplicação de uterotônico em parturientes primíparas durante o terceiro período de trabalho de parto, independentemente da via de administração, e que seu uso é uma medida realizada para o manejo do terceiro período do trabalho de parto.

RESUMEN OBJETIVO: evaluar el uso de uterotónicos en parturientas primíparas durante el tercer período de trabajo de parto, según la vía del parto y los factores asistenciales asociados al mismo, en una maternidad de un municipio de la región de Mata Mineira. MÉTODO: estudio transversal, descriptivo y analítico con 222 mujeres. La recogida de datos se realizó mediante entrevistas. El análisis descriptivo se realizó mediante frecuencias relativas y absolutas. Se utilizó la prueba de chi-cuadrado de Pearson para identificar diferencias estadísticas relacionadas con el uso de uterotónicos, dadas las características sociodemográficas y la atención obstétrica. Se utilizaron modelos de regresión de Poisson para estimar las razones de prevalencia brutas y ajustadas. RESULTADO: más del 80% de las puérperas recibieron uterotónicos independientemente de la vía de administración. Despés de ajustar las características sociodemográficas, se identificó que: no estar en trabajo de parto durante la hospitalización; haber tenido un parto normal; amamantar en la sala de partos; la presencia de un acompañante en la sala de partos; el contacto piel a piel y los masajes para extraer la placenta fueron condiciones asociadas al uso de uterotónicos intramusculares. Se evidenció que: haber sido sometida a cesárea; no amamantar en la sala de partos; no tener contacto piel a piel y no someterse a masajes para extraer la placenta se asociaron al uso intravenoso. CONCLUSIÓN: se observó que durante la atención obstétrica hay factores asociados a la aplicación de uterotónicos en parturientas primíparas durante el tercer período del trabajo de parto, independientemente de la vía de administración, y que su aplicación es una maniobra para el control del tercer período del parto.

ABSTRACT OBJECTIVE: to evaluate the use of uterotonics in primiparous parturient during the third period of labor, according to the route of birth and associated care factors, in a maternity hospital in a municipality in the Zona da Mata Mineira. METHOD: cross-sectional, descriptive, and analytical study with 222 women. Data collection took place through interviews. The descriptive analysis was performed using relative and absolute frequencies. Pearson's chi-square test was used to identify statistical differences related to the use of uterotonics, in view of sociodemographic characteristics and obstetric care. Poisson regression models were used to estimate the crude and adjusted prevalence ratios. RESULT: more than 80% of the puerperal women received uterotonic regardless of the route of administration. After adjusting for sociodemographic characteristics, it was identified that: not being in labor during hospitalization; having had a normal birth; breastfeed in the delivery room; having a companion in the delivery room; having skin to skin contact; and receiving a massage to extract the placenta were conditions associated with the use of intramuscular uterotonics. It was evidenced that: having been submitted to cesarean section; not breastfeeding in the delivery room; not receiving skin-toskin contact; and not being subjected to massage to extract the placenta were associated with intravenous use. CONCLUSION: it was concluded that factors of obstetric care are associated with the application of uterotonic in primiparous parturient during the third period of labor, regardless of the route of administration, and that its use is a measure performed for the management of the third period of labor.

Differences in starting points of active phase and labor duration between preterm and full-term primiparae / 中华围产医学杂志

Objective@#To compare the starting points of the active phase of labor and labor duration between preterm and full-term primiparae and to provide evidence for appropriate labor management.@*Methods@#From January 2013 to December 2016, 925 preterm primiparae (preterm group, 28 to 36+6 weeks) and equal number of full-term primiparae (full-term group, 37 to 41+6 weeks) who delivered in Tianjin Central Hospital of Gynecology Obstetrics were recruited. The starting point of the active labor was defined as the cervical dilatation at the turning point on the cervical dilatation curve where changing from almost flat to the biggest slope. Differences in the starting points and labor duration between the two groups were compared. Statistical analysis was performed using two independent sample t-test, one way analysis of variance and rank-sum test.@*Results@#The duration of the first and second stages [(5.7±2.5) vs (6.8±5.2) h, t=-5.835; (29.9±16.8) vs (34.2±17.2) min, t=-12.637; both P<0.001] and the active phase [M (P95): 1.0 (3.2) vs 1.0 (4.5) h, Z=2.017, P=0.047] of the preterm primiparae were all significantly shorter than those of the full-term primiparae, and the average cervical dilatation rate was significantly accelerated during the active period [M (P5): 6.7 (1.8) vs 5.1 (1.6) cm/h, Z=-2.676, P<0.001]. In the preterm group, women whose starting points of the active phase were at 1 cm, 2 cm, 3 cm, 4 cm, 5 cm and ≥6 cm of cervical dilatation were 25 (2.7%), 275 (29.7%), 258 (27.9%), 203 (21.9%),109 (11.8%) and 55 (5.9%), respectively. While in the full-term group, women whose starting points of the active phase were at 2 cm, 3 cm, 4 cm, 5 cm, 6 cm and >6 cm of cervical dilatation were 74 (8.0%), 208 (22.5%), 287 (31.0%), 168 (18.2%), 127 (13.7%) and 61(6.6%), respectively. In the preterm group, the starting points of the active phase at cervical dilatation≤3 cm, ≤4 cm and ≤5 cm accounted for 60.3% (558/925), 82.3% (761/925) and 94.1% (870/925), respectively. In the full-term group, the percentages of the active phase starting at cervical dilatation≤4 cm, ≤5 cm and ≤6 cm were 61.5% (569/925), 79.7% (737/925) and 93.4% (864/925), respectively.@*Conclusions@#Preterm primiparae may experience shorter labor duration and an earlier start of the active phase than full-term primiparae. The routine labor progression model for full-term primiparae should not be applied to preterm primiparae.

Differences in starting points of active phase and labor duration between preterm and full-term primiparae / 中华围产医学杂志

Objective To compare the starting points of the active phase of labor and labor duration between preterm and full-term primiparae and to provide evidence for appropriate labor management. Methods From January 2013 to December 2016, 925 preterm primiparae (preterm group, 28 to 36+6 weeks) and equal number of full-term primiparae (full-term group, 37 to 41+6 weeks) who delivered in Tianjin Central Hospital of Gynecology Obstetrics were recruited. The starting point of the active labor was defined as the cervical dilatation at the turning point on the cervical dilatation curve where changing from almost flat to the biggest slope. Differences in the starting points and labor duration between the two groups were compared. Statistical analysis was performed using two independent sample t-test, one way analysis of variance and rank-sum test. Results The duration of the first and second stages [(5.7±2.5) vs (6.8±5.2) h, t=－5.835; (29.9±16.8) vs (34.2± 17.2) min, t=－12.637; both P<0.001] and the active phase [M (P95): 1.0 (3.2) vs 1.0 (4.5) h, Z=2.017, P=0.047] of the preterm primiparae were all significantly shorter than those of the full-term primiparae, and the average cervical dilatation rate was significantly accelerated during the active period [M (P5): 6.7 (1.8) vs 5.1 (1.6) cm/h, Z=－2.676, P<0.001]. In the preterm group, women whose starting points of the active phase were at 1 cm, 2 cm, 3 cm, 4 cm, 5 cm and ≥ 6 cm of cervical dilatation were 25 (2.7%), 275 (29.7%), 258 (27.9%), 203 (21.9%), 109 (11.8%) and 55 (5.9%), respectively. While in the full-term group, women whose starting points of the active phase were at 2 cm, 3 cm, 4 cm, 5 cm, 6 cm and >6 cm of cervical dilatation were 74 (8.0%), 208 (22.5%), 287 (31.0%), 168 (18.2%), 127 (13.7%) and 61(6.6%), respectively. In the preterm group, the starting points of the active phase at cervical dilatation≤3 cm, ≤4 cm and ≤5 cm accounted for 60.3% (558/925), 82.3% (761/925) and 94.1% (870/925), respectively. In the full-term group, the percentages of the active phase starting at cervical dilatation≤4 cm, ≤5 cm and ≤6 cm were 61.5% (569/925), 79.7% (737/925) and 93.4% (864/925), respectively. Conclusions Preterm primiparae may experience shorter labor duration and an earlier start of the active phase than full-term primiparae. The routine labor progression model for full-term primiparae should not be applied to preterm primiparae.

Epidural analgesia in latent phase of labor for preeclamptic women attempting vaginal delivery / 中华围产医学杂志

Objective To evaluate the efficacy of epidural analgesia in latent phase of labor for preeclamptic women undergoing vaginal delivery.Methods A prospective study was conducted on 80 nulliparae of singleton pregnancy with preeclampsia and cephalic presentation in Tianjin Central Hospital of Gynecology Obstetrics from August 2016 to July 2017.All subjects were randomly divided into two groups including labor analgesia in active phase group (labor analgesia was commenced at cervical dilation over ≥ 4 cm,n=40,group 1) and the whole labor analgesia in latent phase group (labor analgesia was comenced at the onset of labor,n=40,group 2).Visual analogue score (VAS) was used to evaluate pain intensity at different time points.Maternal venous blood samples were collected at the time of parturient and fetal delivery to determine the serum concentrations of cortisol (Cor) and adrenocorticotropic hormone (ACTH) by enzyme-linked immunosorbent assay (ELISA).Clinical data was statistically analyzed using t-test or Chisquare test.Results (1) Compared with group 1,the duration of the first stage of labor [(521.3±103.5) vs (570.3 ±116.2) min,t=0.366,P＜0.05],the VAS scores immediately after analgesic administration and at cervical dilation of 2 and 3 cm [4.1±1.1 vs 7.3±1.2,3.5±0.9 vs 7.6±1.7,3.7±0.7 vs 8.1±1.4;t=4.387,9.652,5.321;all P＜0.05],the mean arterial pressure at cervical dilation of 2 and 3 cm [(98.3±9.1) vs (125.3±10.6) mmHg (1 mmHg=0.133 kPa),(98.6±10.4) vs (127.5±9.6) mmHg;t=8.014,5.496;both P＜0.05] and the cesarean delivery rate [15.0％ (6/40) vs 27.5％ (11/40),x2=4.012,P＜0.05] were all lower in group 2.(2) The serum levels of Cor [(565±76) vs (231 ±64) nmol/L,(457±79) vs (233±55) nmol/L;t=6.028,5.126;both P＜0.05] and ACTH [(81 ± 14) vs (38±11) pg/ml,(71 ± 16) vs (39±10) pg/ml,t=5.984,6.028;both P＜0.05]in group 1 and group 2 were both increased significantly after delivery as compared with those at the time of parturient,and they also showed significant differences between the two groups after delivery (t=5.009,3.862;both P＜0.05).Conclusions Epidural analgesia in latent phase of labor can be implemented in preeclamptic women attempting vaginal delivery through alleviating labor pain as sooner and earlier as possible,reducing their stress responses and maintain hemodynamic stability.

Effects of analgesia pain relief during entire labor on maternal and neonatal outcomes under new partogram / 中华围产医学杂志

Objective To explore the effects of whole-stage labor analgesia on maternal and neonatal outcomes after the implementation of the new partogram.Methods A retrospective cohort study was performed in Peking University First Hospital.From June to December 2016,907 nulliparae with full-term singleton cephalic pregnancies that were expected to deliver vaginally and adhered to the new partogram were selected as the study group,and 982 cases that adhered to the old partogram (Friedman standard) from June to December 2012 were selected as the control group.Maternal basic characteristics and analgesic,obstetric and neonatal data were collected.Maternal and neonatal outcomes between the two groups were analyzed with independent sample t-test,rank sum test or Chi-square test (Fisher's exact test).Results (1) Maternal age and the proportion of gravidas of advanced maternal age in the study group were both higher than those in the control group [(30.2±3.0) vs (29.64-2.9) years,t=3.823;8.2％ (74/907) vs 4.2％ (41/982),x2=13.087;both P＜0.001].No statistically significant difference in the other basic characteristics was found between the two groups.(2) Women in the study group had significantly smaller cervical dilatation [M(P25-P75)] than that in the control group when analgesia was commenced [2(1-2) vs 2(1-3) cm,Z=-3.752].The intensity of pain quantified with numerical rating scale (NRS) before analgesia,and during the second stage of labor in the study group were less than that in the control group [8(8-9) vs 8(8-10) points,Z=-14.441;5(4-5) vs 6(5-7) points,Z=-16.495].The study group had longer median duration of analgesia than the control group [520(340-750) vs 300(200-453) min,Z=-17.801,P＜0.001].The overall dose of analgesics in injection pump in the study group was significantly higher compared with that used in the control group [68 (35-84) vs 30 (18-48) ml,Z=-18.004,P＜0.001].However,there was no significant difference in the incidence of analgesia-related complications (hypotension,accidental dura puncture,lower extremity numbness,pruritus and urinary retention) between the two groups.(3) The study group showed a higher percentage of spontaneous vaginal delivery,and a lower rate of converted cesarean section compared with the control group [71.8％ (651/907) vs 63.2％ (621/982),x2=15.623;13.6％ (123/907) vs 20.5％ (201/982),~=18.831;both P＜0.001].The study group had lower forceps-assisted vaginal delivery rate than the control group without statistically significant difference [14.8％ (133/907) vs 15.3％ (150/982),x2=0.093,P=0.797].The duration of the first,second and third stage of labor in the study group were all significantly longer than that of the control group [680 (470-900) vs 480 (360-660) min,Z=-12.490;56 (31-89) vs 37 (24-58) min,Z=-9.964;7 (5-10) vs 6 (5-8) min,Z=-6.673;all P＜0.001].Women in the study group had a lower rate of artificial rupture of membranes when comparing with the control group [55.2％ (501/907) vs 63.2％ (621/982),x2=12.516,P＜0.001].The incidence of fever,pathologically confirmed infection and postpartum hemorrhage were significantly higher in the study group than that in the control group [10.8％ (98/907) vs 6.4％ (63/982),x2=11.652;9.6％ (87/907) vs 3.7％ (36/982),x2=27.201;12.6％ (114/907) vs 5.7％ (56/982),x2=27.144;all P＜0.05].There was no significant difference in the rate of oxytocin use during labor or blood transfusion between the two groups.(4) Compared with the control group,the proportion of cesarean section due to arrested active stage of labor in the study group was significantly lower [5.7％ (7/123) vs 50.2％ (101/201),x2=68.173,P＜0.05],but the incidences of cesarean section due to intrauterine infection and relative cephalopelvic disproportion were higher in the study group [61.0％ (75/123) vs 30.8％ (62/201),x2=2.680;20.3％ (25/123) vs 8.0％ (16/201),x2=10.555;both P＜0.05].There was no significant difference in the proportion of fetal distress or other indications for cesarean section between the two groups.(5) There was no significant difference between the two groups in birth weight,macrosomia,fetal distress,neonatal asphyxia,or the proportion of neonatal intensive care unit admission.Conclusions After the implementation of the new partogram,analgesic pain relief covering the whole labor prolongs the average analgesic time and reduces the rate of cesarean section due to arrested active stage of labor.Although the risk of postpartum hemorrhage is slightly increased,analgesia itself does not pose additional risks on forceps-assisted delivery,maternal blood transfusion and neonatal asphyxia.

Using quantile regression to re-evaluate the epidural labor analgesia under new partogram: a prospective cohort study / 中华围产医学杂志

Objective To investigate the influence of epidural analgesia on labor duration under the new partogram recommendations using quantile regression.Methods In this study,we recruited 300 nulliparous women at full term who were hospitalized in Department of Obstetrics and Gynecology,Tongji Medical College,Huazhong University of Science and Technology from May to September,2018.The participants who were willing to receive epidural analgesia during labor were assigned to the epidural group (n=150),and those who were not to the control group (n=150).Labor duration and delivery outcomes were analyzed by Student's t test,Mann-Whitney U test,Chi-square test and Fisher's exact test.Quantile regression models were also used to investigate the effect of epidural analgesia on labor duration.Results The median durations of first-and second-stage labor in the epidural group were 600(400-840) and 66(45-98) min,respectively,which were significantly longer than those of the control group [420(320-610) and 52(33-87) min] (Z=-4.273,P＜0.001;Z=-3.210,P=0.001).Quantile regression analysis showed that,for the first stage of labor,epidural analgesia was associated with labor prolongation,and had significant effects on all the percentiles (all P＜0.05).The regression coefficients increased (95.630-285.000) correspondingly as the percentiles of the labor duration (from 10th to 90th percentiles) increased.For the second stage of labor,epidural analgesia showed a significant impact on prolongation only between the 25th and 75th percentiles (coefficients:10.000～18.143;all P＜0.05).Although the epidural group had a significant higher episiotomy rate [46.8％(65/139) vs 33.3％(48/144),x2=5.318,P=0.021],more times of urine catheterization during labor [1(0-1) vs 0(0-1),Z=-0.974,P=0.001]and higher rate of oxytocin administration during labor [48.7％(73/150) vs 30.0％(45/150),x2=10.952,P=0.001],when compared with the control group,there was no significant difference in cesarean section rate,assisted vaginal delivery rate and neonatal outcomes between the two groups (all P＞0.05).Conclusions Epidural analgesia may associated with the prolongation of the first and second stage of labor,especially with the first stage of labor,but has no adverse effects on maternal and neonatal outcomes.

Analysis of labor progression characteristics of 1089 nulliparas managed by the new partogram / 中华妇产科杂志

Objective To analyze labor progression characteristics among nulliparas and provide reference to labor progress management. Methods A retrospective study was conducted on 1089 women who went for vaginal delivery at the First Affiliated Hospital, Sun Yet-San University from January 1st, 2015 to May 31th, 2016. The duration of cervical dilation from 1.0 cm to the next and the process of initial cervical dilation (2.0 cm or 3.0 cm) to full cervical dilation of nulliparas were analyzed. Results The cervical dilation speed was accelerating with the progress of labor. The rate of cervical dilation changed fastest between 5.0-6.0 cm dilation, which was more than 3.0 cm/hour. With regard to labor curves, at admission of 2.0 cm cervical dilation, it rose dramatically from 5.0 cm dilation. At admission of 3.0 cm dilation, it presented approximately linear rising before 5.5 cm dilation, then became steeper. Conclusions The cervical dilation speed is fast. Both labor curves of initial cervical dilation (2.0 cm or 3.0 cm) to full cervical dilation show obvious acceleration stage with steep slope.

Application of ultrasound in delivery room / 中国实用妇科与产科杂志

One of the new requirements for modern standardized management in obsterics is the use of ultrasound in the delivery room.Ultrasound can help clinicians to identify the fetal condition,fetal presentation and placental location,and the circumstances of uterine and abdominal cavity quickly and accurately in managing obstetric emergencies.It can also guide the management of labour progress,the selection of suitable mode of delivery,the appropriate operation to assist delivery,and the interventional operations. In recent years,there have been many progresses in the application of ultrasound in the labor ward,such as new indicators for the evaluation of labor progressing with ultrasonic,ultrasound-guided anesthesia and tracheal intubation,and evaluation of cardiac volume load and cardiac function and so on.So it can provide further protection for maternal and infant safety.

Changes in the management of delivery room with new labor stage standard / 中国实用妇科与产科杂志

Under the premise of ensuring the health of mother and child,the new labor standard is to reduce human intervention during labor and closely observe the progress of labor stage in order to provide more opportunity for vaginal delivery,advocate humanistic care,promote vaginal delivery,reduce the rate of cesarean section,and provide maximum protection for maternal and newborns safety.

Limited intervention measures for childbirth / 中国实用妇科与产科杂志

In the clinical work of our country,more and more attention is paid to the people-centered concept. It is more focuses on avoiding excessive intervention and strengthening management of labor course. Interventions that should be limited during childbirth for low-risk spontaneous labour.The limited interventions are including the application of the new parturition process criteria,the use of early amniotomy with early oxytocin augmentation for prevention of delay in labour is not recommended,routine cardiotocography is not recommended,encouraging the adoption of a birth position of the individual woman's choicey,routine episiotomy is not recommend,et al.Itis necessary to manage women and their fetus depending on patients' s situation,and to ensure the safety of mother and child.As well as to reduce excessive intervention,thereby reducing caesarean section rate,ensure that the mother has a good delivery experience,and improve the outcomes of mother and child.

Ventajas y desventajas del parto vertical en contraste con el parto horizontal: una revisión de la literatura / Advantages and Disadvantages of Upright Position in Contrast to Supine Position: A Review of Literature / Vantagens e desvantagens do parto vertical em contraste com o parto horizontal: uma revisão da literatura

El parto vertical es una práctica ancestral que puede ofrecer ventajas para la madre y su recién nacido. Objetivo: integrar los hallazgos que informa la literatura sobre ventajas y desventajas del parto vertical en contraste con el parto horizontal. Método: revisión integrativa de la literatura publicada en el periodo 2005-2015. Se seleccionaron quince estudios, luego de un proceso de búsqueda y crítica de literatura. Los datos se extrajeron, analizaron y compararon con apoyo en la herramienta ATLAS.ti, versión 7.0. Resultados: esta revisión integró los hallazgos de los artículos seleccionados, de los cuales emergieron doce subtemas que se clasificaron en los dos temas planteados: ventajas y desventajas del parto vertical en contraste al parto horizontal. Se encontraron las siguientes ventajas: disminución en el tiempo en la segunda etapa, menos desgarros de tercer y cuarto grado, menor edema vulvar, menor necesidad de instrumentación, menor necesidad de episiotomía, menos casos de presión del fondo uterino, menos casos de placenta retenida, menor dolor, mejor percepción de la materna y mejores resultados fetales y neonatales. Como desventajas se encontraron: mayor sangrado y dificultad de mantener la posición. Conclusión: esta revisión encontró que el parto en posición vertical tiene más ventajas en contraste a la posición horizontal, lo que beneficia fisiopsicológicamente tanto a la madre como al neonato.

Upright position is an ancestral practice which can offer advantages to the mother and her newborn. Objective: To intégrate findings from literature on advantages and disadvantages of upright position in contrast to supine position. Methodology: Integrative review of literature published in the period 2005-2015. Fourteen studies were selected after a search process and review of literature. Data were extracted, analyzed, and compared through ATLAS.ti 7.0. Outcomes: This review integrated the findings from the selected articles. Twelve subtopics were grouped into the two topics proposed: Advantages and disadvantages of upright position in contrast to supine position. Among the advantages of this review are: Shorter duration of the second stage of labor, less third- and fourth-degree tears, less vulvar edema, less need for instrumentation, less need for episiotomies, less cases of uterine fundal pressure, less cases of retained placenta, less pain, better mother's perception, and better fetal and neonatal outcomes. As disadvantage, more bleeding and difficulty in maintaining the position. Conclusión: This review found that upright position birth has more advantages in contrast to supine position, thus benefitingphysio-psychologically both to the mother and her newborn.

O parto vertical é uma prática ancestral que pode oferecer vantagens para a mãe e seu recém-nascido. Objetivo: integrar os achados que a literatura informa sobre as vantagens e as desvantagens do parto vertical em contraste com o parto horizontal. Metodologia: revisão integrativa da literatura publicada no período 2005-2015. Foram selecionados 15 estudos, logo de um processo de busca e crítica da literatura. Os dados foram extraídos, analisados e comparados com apoio na ferramenta ATLAS.ti, versão 7.0. Resultados: esta revisão integrou os achados dos artigos selecionados dos quais surgiram 12 sub-temas que foram classificados nos dois temas estabelecidos: vantagens e desvantagens do parto vertical em contraste com o parto horizontal. Foram encontradas as seguintes vantagens: diminuição do tempo na segunda etapa, menos desgarres de terceiro e quarto grau, menor edema vulvar, menor necessidade de instrumentação, menor necessidade de episiotomia, menos casos de pressão do fundo uterino, menos casos de placenta retida, menor dor, melhor percepção da materna e melhores resultados fetais e neonatais. Como desvantagens foram encontradas: maior sangramento e dificuldade de manter a posição. Conclusão: esta revisão indicou que o parto em posição vertical possui mais vantagens comparado com a posição horizontal, beneficiando fisio-psicologicamnte tanto a mãe como o neonato.

Percepção de puérperas sobre a posição vertical no parto / Percepción de puerperas acerca de la posición vertical en el parto / Perception of puerperas on the vertical position in childbirth

Objetivo descrever a percepção de puérperas acerca da posição vertical adotada no trabalho de parto e parto. Método estudo descritivo de abordagem qualitativa desenvolvido em 2014, em uma maternidade de referência de Teresina, Piauí, Brasil. As participantes foram oito puérperas com histórico de parto normal na posição vertical. Os dados foram analisados por meio da técnica de análise de conteúdo. Resultados emergiram quatro categorias: tipo de conhecimento das mulheres sobre as posições verticais; percepção da presença da enfermeira obstetra no processo de parturição como incentivo às posições verticais; recordações da vivência de partos em outras posições; e percepções das puérperas sobre o parto na posição vertical. Conclusões as puérperas avaliaram positivamente a posição vertical de sua escolha e a relacionaram à maior autonomia da mulher no parto, menor intervenção profissional, descida mais rápida do feto, redução do tempo de trabalho de parto, diminuição da dor e maior conforto.

Objetivo describir percepciones de puérperas acerca de la posición vertical adoptada en el trabajo de parto y parto. Método estudio descriptivo, cualitativo, desarrollado en 2014, en maternidad de referencia de Teresina, Piauí, Brasil. Las participantes fueron ocho puérperas con historia de parto normal en posición vertical. Datos analizados por medio de la técnica de análisis de contenido. Resultados surgieron cuatro categorías: tipo de conocimiento de las mujeres sobre posiciones verticales; percepción de la presencia de enfermera obstetra en el proceso de parturición como incentivo a posiciones verticales; recuerdos de la vivencia de partos en otras posiciones; y percepciones de puérperas sobre parto en posición vertical. Conclusiones las puérperas evaluaron positivamente la posición vertical de su elección y la relacionaron a la mayor autonomía de la mujer en el parto, menor intervención profesional, descenso más rápido del feto, reducción del tiempo de trabajo de parto, disminución del dolor y mayor confort.

Objective to describe the perception of puerperae about the vertical position adopted in labor and delivery. Method this is a descriptive study using a qualitative approach developed in 2014 in a reference maternity hospital in Teresina, Piauí, Brazil. Participants were eight puerperal women with a normal vertical birth. Data were analyzed using the content analysis technique. Results four categories emerged: women's knowledge in terms of vertical positions; perception of the obstetric nurse's presence in the parturition process as an incentive to vertical positions; memories of the experience of childbirth in other positions; and perceptions of puerperal mothers on birth in the upright position. Conclusions the puerperae positively evaluated the vertical position of their choice and related it to the greater autonomy of women in childbirth, less professional intervention, faster descent of the fetus, reduction of labor time, decrease of pain and greater comfort.

Manual removal of the placenta in the prevention of postpartum hemorrhage:a Meta-analysis review of randomized controlled trials / 重庆医学

Objective To determine the specific effect of manual removal of the placenta in the third stage of labor in the prevention of postpartum hemorrhage.Methods We searched PubMed,EMBASE,EBSCOhost databases and Chinese Academic Journal et al(inception to October August 2015).Articles database of all published.Randomized controlled trials comparing manual removal of the placenta with hands-off management inthe third stage of labor were included.Two independent reviewers assessed the included studies and extracted data.RevMan4.2 software was used for Meta-analysis.Results Six randomized controlled trials involving a total of 2 435 participants were eligible.There were five cases of cesarean section,one case of natural childbirth,and four English literatures and two Chinese literatures.Significant difference was found between manual removal of the placenta and handsoff management groups with respect to the incidence of postpartum hemorrhage.Conclusion Routine manual removal of placenta at cesarean section significantly increases perioperative blood loss.However,the effect in vaginal delivery need further research.

Determination of a cutoff value for pelvic floor distensibility using the Epi-no balloon to predict perineal integrity in vaginal delivery: ROC curve analysis. Prospective observational single cohort study / Determinação de um valor de ponto de corte para a extensibilidade do assoalho pélvico pelo balão Epi-no para predizer integridade perineal no parto vaginal: análise pela curva ROC. Estudo prospectivo observacional de coorte única

CONTEXT AND OBJECTIVE: Several risk factors are involved in perineal lacerations during vaginal delivery. However, little is known about the influence of perineal distensibility as a protective factor. The aim here was to determine a cutoff value for pelvic floor distensibility measured using the Epi-no balloon, which could be used as a predictive factor for perineal integrity in vaginal delivery. DESIGN AND SETTING: Prospective observational single cohort study conducted in a maternity hospital. METHODS: A convenience sample of 227 consecutive at-term parturients was used. All women had a single fetus in the vertex presentation, with up to 9.0 cm of dilation. The maximum dilation of the Epi-no balloon was measured using a tape measure after it had been inflated inside the vagina up to the parturients' maximum tolerance. The receiver operating characteristic (ROC) curve was used to obtain the Epi-no circumference measurement with best sensitivity and specificity. RESULTS: Among the 161 patients who were included in the study, 50.9% underwent episiotomy, 21.8% presented lacerations and 27.3% retained an intact perineum. Age > 25.9 years; number of pregnancies > 3.4; number of deliveries > 2.2 and circumference measured by Epi-no > 21.4 cm were all directly correlated with an intact perineum. Circumference measurements using the Epi-no balloon that were greater than 20.8 cm showed sensitivity and specificity of 70.5% and 66.7% (area under curve = 0.713), respectively, as a predictive factor for an intact perineum in vaginal delivery. CONCLUSION: Circumferences greater than 20.8 cm achieved using the Epi-no balloon are a predictive factor for perineal integrity in parturients.

CONTEXTO E OBJETIVO: Diversos fatores de risco estão envolvidos nas lacerações do períneo durante o parto vaginal, contudo, pouco se sabe sobre a influência da extensibilidade perineal como um fator protetor. O objetivo foi avaliar o ponto de corte da extensibilidade do assoalho pélvico medido pelo balão Epi-no, o qual poderia ser usado como fator preditor de integridade perineal no parto vaginal. TIPO DE ESTUDO E LOCAL: Estudo prospectivo observacional de coorte única conduzido em maternidade. MÉTODOS: Uma amostra de conveniência de 277 parturientes consecutivas no termo foi utilizada. Todas as mulheres tinham feto único com apresentação cefálica fletida, com até 9,0 cm de dilatação. A máxima dilatação do balão Epi-no foi medida com fita métrica após a sua insuflação dentro da vagina até a tolerância máxima da parturiente. Uma curva característica de operação do receptor (ROC) foi utilizada para obter a medida da circunferência com a melhor sensibilidade e especificidade. RESULTADOS: Dentre as 161 pacientes que foram incluídas no estudo, 50,9% sofreram episiotomia, 21,8% lacerações e 27,3% tiveram o períneo intacto. Idade > 25,9 anos; número de gestações > 3,4; número de partos > 2,2; e medida do perímetro do Epi-no > 21,4 cm foram todos diretamente correlacionados com períneo intacto. Os valores do perímetro com o balão Epi-no que estavam acima de 20,8 cm mostraram sensibilidade e especificidade de 70,5% e 66,7% (área sob a curva = 0,713), respectivamente, como fator preditor de períneo intacto no parto vaginal. CONCLUSÃO: Circunferência medida pelo balão Epi-no maior que 20,8 cm é fator preditor de integridade perineal em parturientes.

The effects of a changed second stage of labor duration on the maternal and neonatal outcomes / 重庆医学

Objective To investigate the influence of the different second stage of labor duration on the maternal and neo‐natal outcomes .Methods Data were retrospectively analyzed from 201 nulliparous women delivering a singleton infant in cephalic presentation without labor analgesia hospitalized in our hospital between January 2012 and May 2015 ,whose second stage pro‐gressed beyond 2 hours .They were divided into observation group and control group according to different second stage of labor du‐ration ,and cases with a second stage of labor duration of three hours were in the observation group (163 cases) ,and those within two hours were in the control group (38 cases) .Results Whether the limit of the second stage of labor duration of 2 hours ,or 3 hours ,the risk of postpartum hemorrhage ,postpartum fever ,urinary retention and neonatal asphyxia ,admission to the neonatology department in two groups were not significantly different(P>0 .05) .However ,there was significance difference in the rate of soft birth canal laceration(72 cases in the observation group) ,poor wound healing (0 case in the observation group and 3 cases in the control group ,P<0 .05) .Conclusion a second stage of labor duration of 3 hours could reduce the rate of cesarean section ,and with no increase in severe adverse maternal and neonatal outcomes .

Clinical effects of epidural labor analgesia with second stage continuous background infusion / 临床麻醉学杂志

Objective To investigate the analgesic effect of epidural labor analgesia with contin-uous background infusion and its impact on obstetric outcome.Methods This was a retrospective co-hort study.In the two months of march 2014 and march 201 5,503 nulliparas women who had re-ceived epidural analgesia for labor were enrolled and assigned to two different study groups according to their analgesic protocol.Two hundred and fifty-eight nulliparas in group C received only patient-controlled analgesia while two hundred and forty-five nulliparas in group P received patient-controlled analgesia with continuous background infusion.The basic and perinatal data of all enrolled nulliparas women were collected and analyzed to compare the analgesic effect and the impact on obstetric risk of two different analgesic protocol.Results The NRS pain score during the second labor stage was lower in group P [3 (3-4)scores vs.5 (4-5)scores](P <0.001).The second stage prolonged [50 (29-82) min vs.38 (24-62)min](P =0.001)and intrapartum hemorrhage increased [200 (100-250)ml vs. 1 50 (100-200)ml](P =0.003)in group P.There were no significant differences between the two groups with regard to the delivery mode (P =0.656)and the morbidity of postpartum hemorrhage (9.8% vs.10.9%,P =0.697).Analgesic protocol with background infusion was not associated with postpartum hemorrhage,instrumental delivery risk and cesarean risk.Conclusion Epidural labor an-algesia with continuous background infusion provided more effective analgesia in nulliparas,without additional obstetric risk.