Reference values for nerve conduction studies in healthy newborns, infants and children in Philippine Children's Medical Center

@#<p style="text-align: justify;"><strong>BACKGROUND:</strong> Nerve conduction studies play a diagnostic role in the clinical evaluation of neuromuscular disorders in children. Reference ranges define the expected parameter values in disease-free children.</p><p style="text-align: justify;"><strong>OBJECTIVE:</strong> To propose reference values for sensory and motor nerve conduction and late responses in upper and lower limb peripheral nerves in Filipino children 5 years and below.</p><p style="text-align: justify;"><strong>METHODS</strong>: Sensory nerve conduction studies on median, ulnar, superficial peroneal, and sural nerves and motor nerve conduction and late response studies on median, ulnar, peroneal and posterior tribal nerves were done using standardized techniques among 100 healthy Filipino children.</p><p style="text-align: justify;"><strong>RESULTS:</strong> Subjects were stratified according to age groups. Reference values for the following parameters: (1) sensory conduction velocity and amplitude; (2) motor conduction velocity, amplitude and latency at distal sites;  (3) F-wave latency; and (4) H-reflex latency were summarized. These were expressed as mean ±standard deviation or median (range) for values that follow Gaussian and non-Gaussian distributions. The 5th and 95th percentile values were likewise reported. Age had direct correlation with various nerve conduction parameters. Height was directly correlated with F-wave parameters of median, ulnar and peroneal nerves but not posterior tribal nerve.</p><p style="text-align: justify;"><strong>CONCLUSIONS</strong>: Reference standards for nerve conduction studies of commonly tested nerves of Filipino children are presented. Values are comparable to reference ranges elsewhere except for the H-reflex latency which is higher in this study.</p>

No Response Rates of Sensory Nerve Conduction Studies and Late Responses in Lower Limbs of Heathy Adults

OBJECTIVE: The purpose of this study was to determine no response rates of sensory nerve conduction studies and late responses in the lower limbs of healthy adults. METHOD: The subjects were 50 healthy adults (mean age, 45.6 years) without the clinical signs and symptoms of peripheral neuropathy. All subjects underwent electrodiagnostic evaluation of the following sensory nerves in lower limbs: superficial peroneal, sural, proximal sural, lateral dorsal cutaneous branch of sural nerve (LDSN), and medial plantar. Examined late responses included: tibial F-wave, peroneal F-wave, and H-reflex recorded from the soleus muscle. RESULT: No response rates of sensory nerve conduction studies such as superficial peroneal, sural, proximal sural, LDSN, and medial plantar nerves were 2%, 0%, 0%, 24%, and 18%, respectively. No response rates of late responses such as tibial F-wave, peroneal F-wave, and H-reflex were 0%, 2%, and 8%, respectively. And no response rates were significantly correlated with age (p<0.05). CONCLUSION: No response rate of sensory and late responses of lower limbs are relevant to age increments, the results should be considered for an early diagnosis of peripheral neuropathy in the lower limbs of old population.

SKIN REACTION TO DERMATOPHAG IDES ALLERGEN / 重庆医科大学学报

It is well know that there are three types of bronchial reaction in asthma; immediate response (IR) , late response (LR) and delayed response (DR).It is also reported that similar responses are seen in the skin.In this study, we examined the three types of skin reaction to dermatophagoides allergen in 111 subjects.30 cases (27%) had a LR, 39 cases (35.1%) had a DR for skin test against dermatophagoid-es allergen.In comparison, only 15 of 140 cases (10.7%) of HD allergen showed a position LR for the HD skin test and 5 (3.6%) a DR for the HD skia test.There was correlation between late onset skin response and severity of nasal symptoms. Late onset skin tests tended to be positive for elder patients. Eosinophils and IgE levels tended to be lower in the LR positive cases. These findings seem to warrant an exemination of the correlation between skin and nasal responses