ABSTRACT
Milia are benign keratinous cysts that present as small, firm, dome-shaped papules. Leprosy is a chronic granulomatous disease caused by M leprae. It is well known to damage skin adnexa, including eccrine glands, due to infiltration of inflammatory cells or by pressure from granuloma formation followed by their subsequent repair. We report a 12-year-old male with multiple milia over a healing plaque of BT Hansen’s disease to highlight the rare presentation where the healing process and not the acute inflammatory reaction was crucial in milia formation because of the occurrence of milia only over resolving lesions without lepra reactions
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Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules.
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Background: Physiological cutaneous changes and clinical presentation is very frequently in neonates. The skin of the new born is covered with greyish white greasy material vernix caseosa, a physiologic protective covering derived partially by secretion of sebaceous glands and in part as a decomposition product of the infant’s epidermis. It acts as a natural protectant to the infant in utero. It should be allowed to come off by itself. Aim: To study the various physiological changes in neonates. Materials and methods: We studied 200 neonates for the pattern of cutaneous changes. 200 neonates were examined within 24 hours of birth over the period of 2 years. We prospectively enrolled and analysed 200 patients with various dermatoses in infants from July 2010- December 2012 in the Department of Dermatology. The complete clinical history was taken and complete physical examination was performed. Types of clinical lesions and their distribution along with mucous membrane lesions were noted; any change in hair, nail, and teeth was noted. Results: Most common cutaneous change observed was Mongolian spots followed by physiological exfoliation and erythema neonatorum. Physiological cutaneous change was observed in 100% neonates. Conclusion: We confirm the variation in physiological cutaneous changes and their time of onset in neonates. This study showed physiological changes were present in all newborn. Number of lesion was more in preterm babies.
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Milia are minute follicular epidermal cysts, commonly found over the cheeks, nose, upper lip, forehead, and rarely over the areolae and genitalia.Prepucial milia (Prepucial Epstein pearl), are pearly white papules, 1-2mm in size found on the prepuce or shaft of the penis in a male new born. They are benign in nature and almost always disappear within a few weeks. Prepucial milia evoke a lot of concern and anxiety to the parents. Physician and child healthcare providers should be aware of this condition to avoid unnecessary intervention.
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Milia are benign primary or secondary keratinous cysts. Multiple eruptive milia (MEM) and milia en plaque (MEP) are rarely reported. A 21-year-old male presented with multiple skin-colored papules on the abdomen and both acral regions, and erythematous plaques featuring similar papules on the wrist and the dorsa of the feet. A biopsy confirmed MEP and he was diagnosed with both MEM and MEP. We thus report a rare case of simultaneous MEM and MEP.
Subject(s)
Humans , Male , Young Adult , Abdomen , Biopsy , Foot , Keratosis , Skin Diseases , WristABSTRACT
We present to you, case of a 10-year-old female with h/o redness, watering since 8 months. Her vision was 20/30 in right eye and 20/70 in left eye. Conjunctiva had plenty of purulent discharge and palpebral conjunctiva was studded with membranous lesions. She was found to have multiple hyperpigmented papulopustular lesions over face, palms and legs. She was started with topical moxifloxacin and lubricating drops. Patient was followed-up after 15 days. At that time her conjunctiva had formation of a woody pseudomembrane. Excision of the lesions and skin biopsy was done and sent for hislopathological examination. Findings of histopathological examination were suggestive of ligneous conjunctivitis and juvenile colloid milia. We have started this patient with long-term cyclosporine drops and tear supplements. In next visit, the membrane was resolved. Hence, we continued with the same treatment, but again the woody membrane recurred.
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El síndrome orofaciodigital tipo I (OFD 1; OMIM #311200) es un trastorno del desarrollo transmitido como un rasgo dominante ligado al cromosoma X con letalidad en varones. Se asocia con manifestaciones clínicas a nivel oral, facial y digital. Se caracteriza, además, por la presencia de quistes de milia, hipotricosis y poliquistosis renal. Se presentan dos casos con diagnóstico clínico de síndrome orofaciodigital tipo I con cierta variabilidad fenotípica entre ellos.
Oral-facial-digital syndrome type 1 (OFD1; OMIM #311200) is a developmental disorder transmitted as an X-linked dominant condition with embryonic male lethality. It is associated with malformation of the oral cavity, face, and digits. Furthermore, it is characterized by the presence of milia, hypotrichosis and polycystic kidney disease. We present two cases with clinical diagnosis oforal-facial-digital syndrome type I with some phenotypic variability between them.
Subject(s)
Humans , Female , Infant , Orofaciodigital Syndromes , Cysts , Ciliopathies , MiliariaABSTRACT
Objetivo: analisar a influência da rhBMP-2 em enxer os bucofaciais, apresentando pesquisas recentes, feitas em animais e em humanos, bem como as diferentes metodologias de aplicabilidade clínica e os resultados obtidos por seus autores. Revisão de literatura: para que seja possível a instalação de implantes ou a correção de defeitos ósseos há necessidade de que exista ecido ósseo de boa qualidade. Sem isso, as possibilidades de sucesso nos procedimentos de osteointegração e reabilitações bucofaciais, visando devolver ao paciente o volume ósseo perdido, são muito reduzidas. As proteínas morfogenéticas ósseas (BMPs) são substâncias osteoindutoras e têm sido utilizadas na regeneração óssea. A procura por materiais que apresentem características semelhantes às alcançadas com o enxerto autógeno, com o objetivo de reduzir a morbidade dos procedimentos de restauração das estruturas ósseas perdidas, fez com que as pesquisas avancem para o lado dos materiais sintéticos, como é o caso da rhBMP-2, principal proteína morfogenética indutora de tecido ósseo. Considerações finais: novos estudos são necessários para analisar a viabilidade e o sucesso da aplicação dessas proteínas. Para tanto, pode-se observar que essas proteínas têm uma excelente função na formação óssea.
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Dermoscopy is a noninvasive technique that is known to increase the accuracy of diagnosing benign versus malignant skin lesions. Milia en plaque is a rare benign epidermal tumor characterized by multiple milia-like lesions within the erythematous edematous base. It arises spontaneously on healthy skin in predisposed individuals without any apparent cause. An 80-year-old woman presented with a solitary coin-sized yellowish to brown plaque on the right cheek. The lesion has been enlarging for several years. Dermoscopic examination showed arborizing telangiectasia, and we suspected it to be basal cell carcinoma. Two biopsies were taken from the lesion, which revealed a keratin-filled cyst lined by a stratified epithelium of a few cell layers and sparse lymphocytic infiltration. Therefore, we diagnosed the lesion as milia en plaque, histopathologically. On the basis of our experience with a case of milia en plaque diagnosed as a basal cell carcinoma with dermoscopic findings, we believe that benign lesions should be considered even in the presence of malignant findings on dermoscopy.
Subject(s)
Aged, 80 and over , Female , Humans , Biopsy , Carcinoma, Basal Cell , Cheek , Dermoscopy , Epithelium , Skin , TelangiectasisABSTRACT
Follicular mycosis fungoides is a distinct variant of mycosis fungoides. Clinically, it occurs mostly in adults, affecting more males than females. It is manifested as pruritic follicular papules, acneiform lesions, or indurated plaques, typically in the head and neck. Histopathologically, it is characterized by infiltration of atypical T lymphocytes with cerebriform nuclei in the follicular epithelium (folliculotropism). We report a case of follicular mycosis fungoides manifested as a milia-like lesion combined with the patch stage of mycosis fungoides, which was treated with radiotherapy.
Subject(s)
Adult , Female , Humans , Male , Epithelium , Head , Mycosis Fungoides , Neck , Radiotherapy , T-LymphocytesABSTRACT
Introdução: Tem sido crescente na clínica fonoaudiológica, no âmbito público ou privado, a demanda por atendimento, a crianças com queixas como: não fala, fala pouco, fala errado, ouapresenta fala ininteligível. No Sistema Único de Saúde, a possibilidade de acolher essa demanda constitui-se uma questão relevante em conformidade com as políticas públicas de saúde, baseada nos conceitos de promoção, prevenção e acolhimento. Objetivo: Verificar a eficácia de um procedimento de acolhimento diferenciado, com fins preventivos, a pais de crianças com queixas de alterações de linguagem oral, que aguardam por atendimento fonoaudiológico no Sistema Único de Saúde. Metódo: Trata-se de pesquisa quanti-qualitativa. Participaram da pesquisa seis famílias em fila de espera numa UBS de São Paulo. Foram utilizados 5 instrumentos: 1-Entrevista Inicial com os pais; 2- Avaliação de Linguagem; 3-Questionário de Habilidades e Dificuldades Comunicativas dos Pais; 4-Protocolo de Observação das Atitudes Comunicativas dos Pais preenchido a partir da filmagem de uma atividade lúdica entre pais e respectivos filho(a) e 1 instrumento que norteou a construção do acolhimento diferenciado: 5- Protocolo de Ações Favoráveis e Desfavoráveis à Comunicação, a Brincadeiras e aos Hábitos Orais. Após 3 meses foram reaplicados os instrumentos 2, 3 e 4, para verificar se houveram mudanças. Resultados: Após o acolhimento diferenciado todas as famílias referiram compreender melhor a fala das crianças. Observou-se aumento geral das atitudes comunicativas favoráveis do tipo: reformulações no discurso; enunciados de continuidade; solicitação de esclarecimento e decréscimo nas atitudes desfavoráveis. Isto mostrou que houve uma repercussão positiva na dialogia, nas interações e, conseqüente, nas habilidades comunicativas das crianças. Conclusão: os resultados apontam que a proposta de acolhimento diferenciado foi efetiva como um dispositivo clínico fonoaudiológico em saúde pública.
troduction: It has been increasing in private or public Speech-Language and Hearing clinicsdemands for care to children with complaints like: do not talk; speaks little; speaks wrong orpresents unintelligible productions. The possibility to accept that demand in the National HealthSystem is a relevant issue in accordance with public health policies based on the concepts of promotion,prevention and care. Goal: Check the efficacy of differentiated care procedure, with preventive purposes, to parents of children with language alterations complaints waiting for speech therapy in the NationalHealth System. Method: Quantitative and qualitative research with participation of six families waitingfor speech therapy in a Health Unit in São Paulo - Brasil. Five instruments were used: 1- Initial Interviewwith parents; 2- Language Evaluation; 3- Communicative Abilities and Difficulties Questionnaire forParents; 4- Communicative Attitudes Observation Protocol for Parents filled in from the filming of aplay activity between parents and their children and an instrument that guided the construction of thedifferentiated care: 5- Favorable and Unfavorable Actions to Communication, Play and Oral Habits.After 3 months the 2, 3 and 4 instruments were re-applied, to check whether there were changes. Results:After the differentiated care all families reported a better understanding of their childrens speech. Ageneral increasing of favorable attitudes like: discourse reformulations, continuity enunciations, requestsfor clarification was observed, and also a decrease in unfavorable attitudes. That showed a positiveimpact on the dialogism, on the resulting interactions and communicative of the children. Conclusion:The results show that the proposed differentiated care was effective as a Speech-Language and Hearingclinical device in public health and may establish new care practices family-centered and centered inthe commitments of...
troducción: Ha sido creciente en la clínica fonoaudiológica, sea en la esfera publica o privada,la búsqueda por atención clínica a niños con quejas como: no habla, habla poco, habla conerrores, o presenta habla ininteligible. En el Sistema Único de Salud (SUS) brasileño, la posibilidadde acoger a esa demanda es una cuestión relevante de acuerdo con las políticas de salud basadas en losconceptos de promoción, prevención y acogimiento. Objetivo: Verificar la eficacia de un procedimientode acogimiento diferente, con fines de prevención, a padres de niños con queja de problemas de lenguajeoral, que esperan por atención clínica fonoaudiológica en el Sistema Único de Salud brasileño.Método: Investigación cuanti-cualitativa. Participaron seis familias que estaban en una fila de esperaen una Unidad Básica de Salud de San Pablo Brasil. Se utilizó 5 instrumentos para coger los datos:1- Entrevista Inicial con los Padres; 2- Evaluación de Lenguaje; 3- Cuestionario de Habilidades yDificultades Comunicativas de los Padres; 4- Protocolo de Observación de Actitudes Comunicativasde los Padres, llenado a partir de la filmación de una actividad lúdica desarrollada entre los padresy 1 instrumento que orientó la construcción del acogimiento diferenciado: 5- Protocolo de AccionesFavorables y Desfavorables a la Comunicación, al Juego y a los Hábitos Orales. Después de 3 mesesfueron aplicados de nuevo los instrumentos 2, 3 y 4, para averiguar si hubieron cambios. Resultados:Después del acogimiento diferenciado todas las familias refirieron comprender mejor el habla de losniños. Se observó aumento general de actitudes comunicativas favorables del tipo: reformulaciones deldiscurso; enunciados de continuidad; solicitaciones de esclarecimiento y disminución en las actitudesdesfavorables. Esto evidenció que hubo una repercusión positiva en la dialogia, en las interacciones yconsecuentemente en las habilidades comunicativas de los niño...
Subject(s)
Humans , Child , Language Development , Public Health , Speech DisordersABSTRACT
Milia are small, white to yellow, benign, superficial keratinous cysts. They are divided into primary or secondary cysts. Secondary milia are associated with disease, medication, and trauma. We report a case of a 45 year-old woman with grouped yellowish papules and brownish patches on her left ankle after bullous cellulitis. This case shows that bullous cellulitis may be one of the causes of secondary milia.
Subject(s)
Animals , Female , Humans , Ankle , Cellulitis , KeratinsABSTRACT
Milia are small, white, benign keratinous cysts that are frequently encountered. Multiple eruptive milia are rare, and are characterized by the development of milia that are more extensive in number and distribution than would be expected in primary milia. We report a case of a 19-year-old girl with tiny, white papules in her axillae and on her abdomen with a review of the relevant literature.
Subject(s)
Humans , Young Adult , Abdomen , Axilla , KeratinsABSTRACT
A 23-year-old man presented with two asymptomatic, yellowish papules surrounded with several whitish papules localized on the right cheek. Gross findings of the whitish lesions corresponded with milia. Histopathologic examinations of yellowish lesions revealed folded cyst walls consisting of several layers of epithelial cells, which were consistent with the diagnosis of steatocystoma. This case could be further proof steatocystoma and milia originate from the same pilosebaceous unit. It is important to differentiate steatocystoma from milia for less scarring after surgical treatment.
Subject(s)
Humans , Young Adult , Cheek , Cicatrix , Epithelial CellsABSTRACT
Milia en plaque is characterized by multiple milia-like lesions within an erythematous plaque. Milia en plaque is a rarely reported entity which usually appears in the auricular region. We report the case of a 72-year-old woman who presented with milia en plaque on the left arm after NSAIDs injection. This is a rare case because there are no records of Milia en Plaque occurring on an arm in Korea.
Subject(s)
Aged , Female , Humans , Anti-Inflammatory Agents, Non-Steroidal , Arm , Upper ExtremityABSTRACT
Milia-like idiopathic calcinosis cutis is a rare entity. It is characterized by micronodular, whitish papules resembling milia. Histopathological examination shows small nodular foci of calcium within the superficial dermis, which are surrounded by thick collagen and inflammatory cells. Although the pathogenesis and treatment remain unclear, spontaneous resolution of the lesions may occur. We report a case of milia-like idiopathic calcinosis cutis in a 7-year-old girl who improved after treatment with tretinoin cream.