Analysis on the change of distribution of the major non-fermenting bacilli and the sensitivity of antibiotics from 2014 to 2016 / 国际检验医学杂志

Objective To investigate the distribution and antibiotics resistance of the major non-fermenting bacteria in our hospital from 2011 to 2016 ,then provide a reference for clinic practice .Methods Retrospective-ly analyze clinical distribution and antimicrobial susceptibility of 2398 non-fermenting bacteria from 2014 to 2016 .Results Over the past 3 years ,2398 main non fermented bacteria were isolated ,mainly 1019 strains of Acinetobacter Bauman (42 .5％ ) ,followed by Pseudomonas aeruginosa 1016 (42 .4％ ) .The main non fermen-tative bacteria isolated from ICU were 727 strains (30 .3％ ) ,ranking the first in all departments ,and the Acin-etobacter Bauman was the top .The sensitivity rate of Acinetobacter Bauman to antibiotics was decreasing year by year ,as low as 25 .0％ -40 .0％ .Especially in ICU ,the sensitivity rates were less than 10 .0％ .The suscep-tibility rates of Pseudomonas aeruginosa to a variety of antibiotics ,such as ceftazidime ,cefepime ,imipenem , ciprofloxacin ,levofloxacin ,were all increased ,and the sensitivity was >70 .0％ .Conclusion Acinetobacter and Pseudomonas aeruginosa were the main pathogenic bacteria in the clinical distribution of non fermenting bacte-ria .The most sensitive rate of the former to antibiotics was decreasing year by year ,especially the ICU situa-tion was severe ,the sensitivity of the latter was increasing year by year ,which was beneficial to the clinical se-lection of antimicrobial agents .

Lower respiratory tract in patients with malignant tumor of fermentation bacteria infection of bacterial drug resistance analysis / 国际检验医学杂志

Objective To understand the drug resistance in cancer patients with secondary non-fermenting bacterial lower respir-atory tract infection in order to provide a basis for clinical rational use of antibacterial drugs.Methods The lower respiratory tract specimens were collected from the patients with malignant tumor and identified by the fully automated microbial identification sys-tem,the drug susceptibility test was performed by using K-B method and the drug susceptibility test results were judged according to CLSI 2012 standard.The data were analyzed by the WHONET 5.6 software.Results 172 strains of non-fermenting bacteria were isolated from the lower respiratory tract specimens in the patients with malignant tumors,in which Pseudomonas aeruginosa was maximum,accounted for 45.9%,followed by Acinetobacter baumannii and Stenotrophomonas maltophilia ,accounted for 36. 0% and 10.5 % respectively.The drug susceptibility test showed that five kinds of non-fermenter demonstrated the high resistance or multi-resistance to multiple antibacterial drugs.Conclusion Non-fermenting bacterial multi-drug resistant phenomenon is seri-ous,clinic should pay attention to non-fermenting bacterial infection and drug resistance monitoring,antibacterial drugs should be rationally used according to the drug susceptibility test results in order to reduce the generation of drug-resistant strains.

Surveillance of Antimicrobial Resistance and Classification in Non-fermenting Bacteria Isolated from Lower Respiratory Tract for 3 Consecutive Years / 中华医院感染学杂志

OBJECTIVE To investigate the distribution and resistance of non-fermenting bacteria isolated from our hospital and offer the basis for the treatment of bacterial infection.METHODS Totally 2177 strains of non-fermenting bacteria were isolated from clinical sputum samples between Jan 2006 and Dec 2008.All of the isolated bacteria were identified with API identified test(API Inc,France) and Kirby-Bauer(K-B) test used for the antibiotics susceptive test.RESULTS From them the most common bacteria were Pseudomonas auruginosa(34.9%),followed by Acinetobacter baumannii(28.4%) and Stenotrophomonas maltophilia(11.4%).These bacteria had various resistances to the tested antibiotics.CONCLUSIONS Non-fermenting bacteria have high isolate rate and multi-antibiotic resistance,so antibiotics should be correctly used under the guidance of antibiotic susceptibility test.

Isolation and Identification of 236 Strains Non-fermenting Bacteria and Their Antibiotic Resistance Analysis / 医学研究杂志

Objective To investigate the distribution and resistance of non-fermenting bacteria isolated from our hospital and offer a basis for the treatment of bacterial infection.Methods 236 strains of non-fermenting bacteria were isolated from clinical samples between May.2004 and Dec.2006were identified with API identified test (API Inc.France) and Kirby-Bauer (K-B) test used for the antibiotics susceptivity test. Results Totally 236 strains of non-fermenting bacteria were isolated from the 1303 pathogenic strains. The most common bacteria were Pseudomonas auruginosa(57.6%),followed by Acinetobacter baumannii(7.6%)and Pseudomonas putida(6.4%).64%of non-fermenting bacteria were isolated from the sputum. these bacteria had various resistance to all detected antibiotics. Conclusions non-fermenting bacteria had high isolated rate and multi-antibiotic resistance,so antibiotics should be correctly under the guidance of antibiotic susceptibility testing.

Isolation and Identification of Non-fermenting Bacteria and Their Antibiotic Resistance Analysis / 中华医院感染学杂志

OBJECTIVE To investigate the distribution and resistance of non-fermenting bacteria isolated from(patients) in 2005 and offer a basis for the treatment of bacterial infection.METHODS The isolated bacteria were(identified) with API identified test(API Inc,France) and Kirby-Bauer(K-B) test used for the antibiotics(susceptivity) test.The data were analyzed by using WHONET-5 software.RESULTS Totally 604 strains of non-fermenting bacteria were isolated from the 2908 pathogenic strains.The most common bacteria were Pseudomonas aeruginosa(52.32%),followed by Stenotrophomonas maltophilia(14.07%) and Acinetobacter baumannii((13.74%)).76.32% of non-fermenting bacteria were isolated from the sputum.These bacteria had various(resistances) to all detected antibiotics.CONCLUSIONS Non-fermenting bacteria have high isolation rate and(multi-drug) resistance,so antibiotics should be used correctly under the guidance of antibiotic susceptibility testing.