ABSTRACT
Objective: To investigate the chemical constituents from the Seeds of Nelumbo nucifera. Methods: The chemical constituents were isolated by repeated silica gel chromatography, Sephadex LH-20 gel columns chromatography, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscopic analyses. Results: Thirteen compounds were identified to be p-methoxyphenylacetic acid (1), quercetin-3-O-α-L- arabinoside (2), apigenin-6-C-arabinoside-8-C-glucoside (3), naringenin (4), stigmast-4-en-3-one (5), quercetin-3-methyl ether (6), vitexin (7), cosmoslin (8), quercetin (9), apigennin (10), luteolin (11), kaempferol (12), and astragalin (13). Conclusion: Compounds 1-3, 5 and 6 are obtained from the plants of Nelumbo Adans for the first time, and compound 8 is obtained from Nelumbo plumula for the first time.
ABSTRACT
Objective: To study the chemical constituents from the effective fraction in pericarps of Juglans mandshurica. Methods: The compounds were isolated and purified by various chromatographic methods, including silica gel, Sephadex LH-20, and preparative high performance liquid chromatography. Their structures were elucidated by NMR and MS analyses. Results: Fifteen compounds were obtained and identified as kaempferol (1), oleanolic acid (2), chrysophanol (3), pinostrobin (4), (2S)-onysilin (5), juglanin B (6), (S)-regiolone (7), chlorogenic acid (8), (4S)-4-hydroxy-1-tetralone (9), (4S, 5S, 7R, 8R, 14R)-8, 11-dihydroxy-2, 4-cyclo-eudesmane (10), 5-hydroxy-3, 7, 3', 4'-tetramethoxyflavone (11), (2S)-5, 7, 4'-trihydroxy-dihydroflavonol (12), p-hydroxybenzonic acid (13), p-methoxyphenylacetic acid (14), and 1, 4-dihydroxybenzene (15). Conclusion: Compounds 8-15 are first isolated from the pericarps of J. mandshurica and compounds 11, 12, 14, and 15 are obtained from the plants of Juglans L. for the first time.