ABSTRACT
OBJECTIVE: To study the chemical constituents of Yao medicine, Zhongliuteng, the stems of Pileostegia tomentella. METHODS: The chemical constituents were isolated and purified by silica gel chromatography repeatedly, and their structures were identified by spectral analysis and chemical METHODS. RESULTS: Thirteen compounds were isolated from the stems of P. tomentella and the structures were identified as 1-O-(β-D-glucosyl)-2-[2-methoxy-4-(ω-hydroxypropyl) phenoxy]propan-3-ol(1), (+)-lyoniresinol-3a-O-β-D-glucopyranoside (2), syringin (3), coniferin (4), dihydroconiferin (5), but-3-enyl-β-D-glucoside (6), 4-(2, 3-dihydroxypropyl)-2, 6-dimethoxy phenyl β-D-glucopyranoside (7), nikoenoside (8), protocatechuic acid ethyl ester (9), 8-methoxy coumarin-7-O-β-D-glucopyranoside (10), 6-O-R-L-rhamnopyranosyl-β-D-glucopyranoside methyl salicylate (11), nicotinamide (12), and 3, 5-di-O-caffeoyl quinicacid methyl ester (13). CONCLUSION: All compounds were obtained from the genus for the first time.
ABSTRACT
Objective: To study the chemical constituents of Yao medicine Zhongliuteng, the canes of Pileostegia tomentella. Methods: The chemical constituents were isolated and purified by silica gel chromatography repeatedly from the canes of P. tomentella and their structures were identified by spectral analysis and chemical methods. Results: Sixteen compounds were isolated from the canes of P. tomentella and their structures were identified as loganic acid (1), 4-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside (4S)-4-hydroxyl-β-ionone (2), resorcinol (3), daphnin (4), skimmin (5), umbelliferone (6), vogeloside (7), diethyl phthalate (8), secologanin (9), secologanin dimethyl acetal (10), sweroside (11), foliasalacioside B (12), benzyl-O-β-D-apiofuranosyl-(1″→6')-β-D-glucopyranoside (13), maltose (14), glucose (15), and daucosterol (16). Conclusion: All compounds are obtained from the plant for the first time, and all compounds are also obtained from the plants of Pileostegia Hook. f. et Thoms. for the first time except compounds 5, 6 and 16.