ABSTRACT
Objective@#To explore the characteristics of event-related potential(ERP) in the development of alert attention of children aged 6-11 years old.@*Methods@#A total of 144 children aged 6-11 years old were enrolled in a continuous performance test (CPT, Go/Nogo stimulus task). The latency and amplitude of frontal region cue/uncue-P3 and CNV were analyzed and compared in all age groups.@*Results@#(1)Behavioral comparison among different age groups: correct number(35(31, 38), 37(34, 38.25), 37(34.75, 39), 38(35, 39.25), 39(37.25, 40), 39(39, 40)), correct reaction time((566.88±86.63)ms, (530.10±83.40)ms, (509.17±88.99)ms, (488.31±76.23)ms, (463.45±75.78)ms, (417.24±75.78)ms), the differences were statistically significant(P<0.01). (2)Fz lead ERP characteristics: ①Comparison of cue-CNV and uncue-CNV: 6-year-old group((-8.54±4.56)μV vs (-10.13±6.36)μV), 7-year-old group((-9.20±5.34)μV vs (-11.53±4.29)μV), 8-year-old group((-8.37±4.78)μV vs (-11.35±6.38)μV)in amplitude and 9-year-old group((689.25±268.22)ms vs (826.13±174.62)ms)in latency were significantly different(P<0.05). ②Comparison of cue-P3 and uncue-P3: 6-year-old group((4.29±4.11)μV vs (7.45±3.83)μV), 7-year-old group((4.47±4.71)μV vs (5.82±4.40)μV), 8-year-old group((3.76±3.39)μV vs (6.24±4.91)μV), 9-year-old group((4.27±3.57)μV vs (5.93±3.08)μV), 11-year-old group((4.24±4.66)μV vs (6.13±4.42)μV)in amplitude were significantly different(P<0.05). ③Longitudinal comparison among age groups: the latency of cue-CNV in 9-year-old group and 11-year-old group were shorter, and the difference was significant(P<0.05). The amplitudes of cue-CNV and cue-P3 in 10-year-old group were shorter than those in other age groups(P<0.05).@*Conclusion@#With the increase of age, the reaction time of school-age children shortened and the correct rate improved.The age of 9-10 may be the high-speed period of the development for brain network on vigilant attention and psychological prediction which may be related to the maturation and development of frontal cortex.
ABSTRACT
Objective To explore the characteristics of event-related potential(ERP) in the development of alert attention of children aged 6-11 years old.Methods A total of 144 children aged 6-11 years old were enrolled in a continuous performance test (CPT,Go/Nogo stimulus task).The latency and amplitude of frontal region cue/uncue-P3 and CNV were analyzed and compared in all age groups.Results (1)Behavioral comparison among different age groups:correct number(35 (31,38),37 (34,38.25),37 (34.75,39),38(35,39.25),39(37.25,40),39(39,40)),correct reaction time ((566.88± 86.63) ms,(530.10±83.40) ms,(509.17±88.99)ms,(488.31±76.23)ms,(463.45±75.78)ms,(417.24±75..78)ms),the differences were statistically significant (P＜ 0.01).(2) Fz lead ERP characteristics:①Comparison of cueCNV and uncue-CNV:6-year-old group((-8.54±4.56) μV vs (-10.13±6.36) μV),7-year-old group ((-9.20±5.34) μV vs (-11.53±4.29) μV),8-year-old group((-8.37±4.78) μV vs (-11.35±6.38) μV) in amplitude and 9-year-old group((689.25±268.22) ms vs (826.13± 174.62) ms) in latency were significantly different (P＜0.05).(②)Comparison of cue-P3 and uncue-P3:6-year-old group((4.29±4.11) μV vs (7.45±3.83) μV),7-year-old group((4.47±4.71) μV vs (5.82±4.40) μV),8-year-old group((3.76± 3.39) μV vs (6.24 ± 4.91) μV),9-year-old group ((4.27 ± 3.57) μV vs (5.93 ± 3.08) μV),11-year-old group ((4.24±4.66) μV vs (6.13 ±4.42) μV) in amplitude were significantly different (P＜ 0.05).③Longitudinal comparison among age groups:the latency of cue-CNV in 9-year-old group and 11-year-old group were shorter,and the difference was significant(P＜0.05).The amplitudes of cue-CNV and cue-P3 in 10-year-old group were shorter than those in other age groups(P＜0.05).Conclusion With the increase of age,the reaction time of school-age children shortened and the correct rate improved.The age of 9-10 may be the highspeed period of the development for brain network on vigilant attention and psychological prediction which may be related to the maturation and development of frontal cortex.