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【Objective】 To systematically evaluate the effect of applied muscle tension (AMT) exercises on reducing vasovagal reactions(VVRs) among blood donors by meta-analysis. 【Methods】 Nine related databases including MEDLINE, Web of Science and CINAHL were searched using "applied muscle tension" and "vasovagal reactions" as keywords to collect clinical studies on the effects of AMT exercise on VVRs during blood donation. Two researchers independently screened, evaluated the quality and extracted data from the retrieved literature according to the inclusion and exclusion criteria. RevMan 5.4 was used to conduct meta-analysis on the extracted data. 【Results】 A total of 7 articles were finally included, 5 in English and 2 in Chinese, covering 6 808 blood donors. The experimental group performed AMT during blood donation, while the control group did not. Compared with the control group, the difference in reducing the incidence of VVRs [ RR = 0.60, 95%CI (0.42, 0.87), P<0.01] was statistically significant in the AMT group. 【Conclusion】 AMT can effectively reduce the incidence of VVRs during blood donation. However, due to the limitation in the included studies, high-quality studies with perspectiveness, multicenter, large-sample size are further needed for validation in the future.
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【Objective】 To systematically evaluate the characteristics of adverse reactions to blood donation(ARBD) among whole blood donors in China, so as to provide scientific basis for the prevention and control of adverse reactions related to blood donation. 【Methods】 PubMed, EMbase, CNKI, VIP and WanFang Data were retrieved to collect research literature concerning ARBD among whole blood donors in mainland China with observation time≥6 months. The retrieval time was set from the time of database establishment to June 2020. The literature was supplemented by reference tracing and manual retrieval. Two reviewers independently screened the literature, extracted the data, and evaluated the methodological quality of the included studies according to the inclusion and exclusion criteria. Then Review Manager 5.3 software was used for Meta analysis. 【Results】 A total of 36 literature were included, involving 3 769 415 blood donors and 38 403 cases of ARBD. Meta-analysis results showed that the overall incidence of ARBD among whole blood donors was 1.36% [95%CI (1.19, 1.54)], and 1.52% [(95%CI (1.26, 1.78)] in the eastern, 1.26% [(95%CI (0.87, 1.70)] in the central, and 0.76% [(95%CI (0.74, 1.21)] in the western China when stratifying by geographic distribution, with statistically significant differences (P<0.01). The incidence of ARBD in male and female whole blood donors was 1.19% [(95%CI (0.99, 1.39)] and 1.26% [(95%CI (1.05, 1.48)), respectively, which was more commonly reported by women than by men (P<0.01). The incidence of ARBD was 2.17% [(95%CI (1.82, 2.52)], 0.98% [(95%CI (0.82, 1.14)] and 0.76% [(95%CI (0.61, 0.91)] in the age groups of 18~24, 25~40, and 41~55, respectively, and the incidence in donors aged 18~24 years was significantly higher than that in other two age ranges (P<0.01). The incidence of ARBD in first-time and repeat blood donors was 1.57% [(95%CI (1.35, 1.79)] and 0.63% [(95%CI (0.56, 0.70)), respectively(P<0.01). The incidence of ARBD with blood donation <400 mL and 400 mL was 1.10% [(95%CI (0.90, 1.30), P<0.001] and 0.87% [(95%CI (0.71, 1.03), P<0.001], respectively(P<0.01). 【Conclusion】 In order to improve the effectiveness of ARBD monitoring, it is necessary to unify the standards for ARBD, strengthen the knowledge training of ARBD, and accelerate the information construction to explore the national ARBD monitoring mode.
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【Objective】 To analyze the related factors and countermeasures of adverse reactions to whole blood donation(ARBD) for medical student donors, so as to further reduce the incidence of ARBD. 【Methods】 The demographic data of medical/non-medical student donors and those suffered from ARBD from 2016 to 2018 were retrospectively analyzed, and the relationship between ARBD and age, gender, frequency of blood donation, blood volume, blood type, pulse, ALT, blood pressure, hemoglobin, etc. was statistically analyzed. 【Results】 The incidence of ARBD in all medical student donors from 2016 to 2018 was 1.16%, lower than that of non-medical students (1.51%). The ARBD rate(2.30%) of senior medical students (> 20 years old) was significantly lower than that of non-medical students (3.93%) and higher than that of junior medical students (≤20 years old)(0.70%). The ARBD rate of novel medical student donors was 1.27%, lower than that of novel non-medical students (2.12%) (P<0.05). Male medical students(1.68%) were more likely to develop ARBD than females(0.78%), donations within 200 mL(55%) than 300mL(0.26%) and 400mL(0), Hb<120 g/L(13.04%) than Hb≥120 g / L( 1.10% ), and blood type A(1.70%) than type O (0.88%) (P<0.05). Logistic regression analysis showed that blood volume and blood type were related factors. ARBD was more likely to occur in Type A blood than type O, and was more likely to occur when blood volume was lower. ARBD occurred frequently during phlebotomy, due to mental stress(75%) and hunger(8.92%)(P<0.05), while 96.43% of ARBD could recover within 10 minutes. 【Conclusion】 Novel, male, older than 20 years, Hb<120 g / L, blood type A and donation unit ≤200 mL were main risks for ARBD in medical student donors. Popularizing the knowledge of voluntary blood donation and strengthening pre-donation communication are important measures to prevent ARBD.
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Objective To analyze the related factors of donor′s donation reaction in first time apheresis platelets to provide a basis for formulating the preventive measures of donation reactions in apheresis platelets.Methods The donation data in 743 cases of first time apheresis platelet in this blood station were retrospectively analyzed,and the factors possible influencing the donation reaction occurrence in donors of the first time apheresis platelet were performed the univariate Logistic regression analysis,then observation indicators with statistical significance were performed the multivariate Logistic regression analysis.Results The univariate Logistic regression analysis showed that gender,age,body mass,whole blood donation history were the influencing factors of donors′ donation reaction in the first time apheresis platelets.In multivariate Logistic regression analysis,the main factors were age (OR=0.301,P<0.05),body mass (OR=0.411,P<0.05)and whole blood donation history(OR=0.441,P<0.05).Conclusion Age,body mass and whole blood donation history are the main influencing factors of donors′ donation reactions in the first time apheresis platelets.
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Objective To summarize the experience of humane care on our voluntary blood donors.Methods From March 1,2017 to March 31,2017,281 blood donors were enrolled,called the intervened group,from the fixed blood donation street-spot to investigate their satisfaction and their willingness to donate blood again or not.Meanwhile,168 donors who were not intervened were also observed,called the control group.Results In the intervention group,182 were former blood donors,and 64.5％ of the respondents believed that the staff was more trustworthy than before.And 78.2％ of the respondents expressed that the communication ability with blood donors was better than before.The incidence of adverse effect of blood donation in the 281 donors was only 0.71％,and all of them were willing to donate again,which was better than the control group.Conclusion Humanistic care during voluntary blood donation is beneficial to improve the quality of service,the satisfaction of blood donation,and help retaining the blood donors.