Study on a selection of domestic standard for distributing delta3 - cefaclor to quantify and quality the cefaclor by high performance liquid chromatography

System suitability tests are an integral part of liquid chromatographic technique. They are used to verify the resolution (R) and reproducibility of the analysis to be done. HPLC method for assaying the related substances test of Cefaclor in raw material as well as in pharmaceutical dosage forms introduced to some pharmacopoeia such as EP, USP need to use Delta- 3 cefaclor as the internal standard to verify the suitability of chromatographic system. In case of lacking it to use, Cephalexin can be used as the internal standard in place of Delta-3 cefaclor. cell

Study on the cells in the cerebro-spinal fluid by CYTOSPIN technique in 107 patients in the Ho Chi Minh center for Hematology and Blood Transfusion

Study on 107 cases from Jan 1999 to Aug 1999, their results are found as follows: - All in adults: 25 cases (23.36%). Male - female ratio: 1.08 - all in children (treated to Fralle 93): 70 cases (65.43%). Male- female ratio: 1.7. All in the number of WBC > 50 x 109/l: 2 cases (1.87%). AML type M4: 1 case (0.93%). -AML type M5: 2 cases (1.87%). CML transformed to ALL: 1 case (0.93%). Lymphoma: 4 cases (3.74%), 100% male.- Patient with meningeal syndrome: 2 cases (1.78%). From the above results, we have some conclusions as follows: * The types of high meningeal recurrence are: -Early meningeal recurrence: 85.71% - Simple meningeal recurrence: 85.71% - Patients incompletely cured to standard protocol: 64.29%. *The incidence of the central nervous damage caused by ALL in children (20%) is higher than adults (12%). * As to ALL in children, the incidence of meningeal recurrence increases depending on risk group: group C>group B> group A. *Children completely cured to the standard protocol (Fralle93) has a substantially decreased menigeal recurrence (29%, decreased for group B, and 34% decreased for group C).