ABSTRACT
Background: The objective of this study was evaluation of symptomatic women with cervical erosion.Methods: Prospective clinical study done in the department of obstetrics and gynecology, VIMS, Ballari for one-year period from June 2016 to May 2017. All patients with symptoms of white discharge, post coital bleeding and menstrual irregularities were examined by per speculum examination and all those who had cervical erosion (112 Patients) were included in the study. Pap smear and colposcopy were done in all subjects. Colposcopic guided biopsy was done in women with abnormal findings on colposcopy. Histological prediction of colposcopic findings was done according to the Reid’s modified colposcopic index. The result of the biopsy was correlated with the predicted histology of the Reid’s modified colposcopic index and statistical analysis done to calculate diagnostic efficacy of colposcopy in the evaluation of symptomatic women with cervical erosion.Results: Out of the 112 patients, 5.35% (6/112) had abnormal Pap smear. All patients underwent colposcopy and colposcopic guided biopsy, 11.6% (13/112) had abnormal colposcopic findings. Histopathology confirmed CIN I in 6.25% (7/112) and CIN II in 1.78% (2/112) patients. The sensitivity, specificity, PPV, NPV and accuracy of PAP smear was found to be 22.22%, 96.11%, 33.33%, 93.39% and 90.17%. The above values for colposcopy were found to be 88.89%, 95.15%, 61.54%, 98.99% and 94.64%.Conclusions: Colposcopy should be done in all symptomatic patients with cervical erosion as it is a good diagnostic tool for premalignant conditions of the cervix and correlates well with histopathological findings.
ABSTRACT
Objective:To analysis awareness,attitudes and behavior conditions of cervical cancer screening in rural women with cervical erosion. Methods:From Mar 25, 2015 to Sep 25, 2015, 700 rural women with cervical erosion were checked-out in reproductive health survey. Self-designed questionnaire was used. Results:Awareness, attitudes, behaviors situation of cervical cancer screening existed some differences in 686 rural women with cervical erosion. Cognition was correlated positively with cultural level, occupation, household income. Awareness of younger or older person was poorer, their attitudes and understanding was positively correlated with the precancerous screening. Conclusions:Awareness of rural women with cervical erosion on cervical cancer screening can affect health attitudes and behavior. So, the strengthening of the awareness of cervical erosion and cervical cancer screening can essentially improve prevention efforts.
ABSTRACT
Cervical erosion is one of the commonest gynecological diseases which includes large section of women among her reproductive age group and needs medical attention and non surgical treatment In modern system its treatment done with diathermy and cryosurgery which has various side effect like cervical stenosis, accidental burns, etc. In Ayurveda science treatment of karnini yonivyapada by kaphahara chikitsa with Apamarga kshara which have property of lekhana, sodhana, ropana, stambhana, kaphghna and so many properties and Jatyadi taila which have property of vatashamak ,sheshmhara, mansapkarshana, shodhana and ropana . All these properties facilitate destruction of columnar epithelium and facilitate the re-epithelization of new healthy stratified squamous epithelium on ectocervix with this entire basis, this research work was done. karnini yonivyapada described in ayurvedic text books can be correlated with cervical erosion. Apamarga kshara ( Sushruta Samhita Sutrasthana-11/5) and Jatyadi taila ( Bhava Prakash Madhyama Khand.- 47/90-95) . Group I- this group 15 registered patients were administered with application of 'Apamarga kshara' on cervix and 'Jatyadi Taila' Pichu in the vagina for 7 sitting alternate day in a month Group II- In this group 15 registered patients of Cervical erosion were administered with 'Jatyadi Taila ' Pichu in the vagina daily for 14 days in a month. Treatment was done after bleeding phase of menstrual cycles over. Overall percentage relief was higher in group I 72.17% followed by group II i.e. 68.44% . Statistically the results were highly significant (p<0.001) in both groups. Combined use of kshara karma and Jatyadi taila pichu (Group I) is more effectively helps in managing the disease cervical erosion.
ABSTRACT
Objective To analyze humanized nursing measures for improving therapeutic effects in patients with cervical erosion.Methods We 80 patients with cervical erosion admitted in our hospital from March 2012 to September 2014.According to random number table,they were divided into two groups,the observation group and the control group,with 40 patients in each.patients in both groups were treated by LEEP knife circumcision surgery.The observation group was given humanized nursing,and the control group was traditional nursing.The effective rate of treatment,the incidence of postoperative complications and the scores of Self-Rating Anxiety Scale and Self-Rating Depression Scale was compared between two groups.Results The total effective rate of treatment in observation group was 92.5％,which was 75.5％ in control group.The difference was statistically significant (P＜ 0.05).The incidence of postoperative complications of observation group was 10.0％,which was 32.5％ in control group.The difference had statistically significant (P ＜0.05).significantly lower than that of control group (27.8％).All the differences were statistically significant (P＜0.05).Before given nursing,the scores of SAS and SDS between two groups were no significant difference (P ＞0.05) The scores in observation group were significantly lower than those of control group (P＜0.05) Conclusion The humanized nursing measures can improve the therapeutic effects of patences with cervical erosion,promote the recovery of patients' physical and mental health,and is worth of further clinical application.
ABSTRACT
Objective To explore the clinical efficacy of Baofukang suppository and policresulen in the treat-ment of cervical erosion,and to observe and analyze the safety,thus to provide the basis for clinical treatment.Methods 268 patients with cervical erosion were selected,they were randomly divided into the control group and the observation group,134 cases in each group.The control group was treated with Baofukang suppository on the basis of conventional treatment.The observation group received Baofukang suppository and policresulen treatment.To assess the treatment effect of the two groups,and the wound healing time,improvement of the symptoms or signs and the vaginal adverse reactions were observed.Results The total effective rate of the observation group was 88.81% (119 /134),which was higher than that of the control group 79.85% (107 /134),the difference was statistically significant (χ2 =9.87, P 0.05).Conclusion Baofukang suppository combined with policresulen has better clinical curative effect in the treatment of cervical ero-sion,which can shorten the wound healing time,reduce symptoms or signs of patients,and has high security.
ABSTRACT
Objective To investigate the current infection situation of Chlamydia trachomatis (CT) and Ureaplasma urealyticum (Uu) in patients with cervical erosion .Methods CT and Uu were detected in cervical secretions of 562 cases of cervical erosion pa‐tients (observation group) and 218 healthy controls (control group) .Drug susceptibility testing was performed for the patients with Uu infection .Results Positive rate of CT ,Uu and mixed infection was 20 .11% ,42 .35% and 9 .61% ,higher than those of control group (P0 .05) ,while the positive rate of CT ,Uu and mixed infection was significantly different between the two groups and mild cervical erosion (P<0 .05) .The highest susceptibility rate of Uu to antimicrobial agents was josamycin (91 .78% ) ,followed by pristinamycin (84 .25% ) .The highest resistant rate of Uu was to ciprofloxacin (85 .96% ) ,followed by ofloxacin(73 .29% ) .Conclu‐sion The infection of CT and Uu could be intimate correlated with cervical erosion and the extent of erosion .Varying degrees of drug resistance of Uu could be found ,and the sensitive and effective antibiotics should be chosen to treat cervical erosion infection of Uu .
ABSTRACT
Objective:To discuss the curative effect of lacidophilin vaginal capsules combined with loop electrosurgical excisional procedure ( LEEP) in the treatment of cervical erosion with chronic cervicitis. Methods:Totally 72 cases of patients with cervical ero-sion with chronic cervicitis were selected and divided into the observation group and the control group at random. The patients in the two groups were given routine LEEP with the application of antibiotics to prevent infection for 1 week. The patients in the observation group were additionally given lacidophilin vaginal capsules, placed in the vagina after the operation, one capsule per time at every night for 14 days. The vaginal fluid time and vaginal bleeding time in the two groups were observed. The clinical curative effect and adverse drug reactions ( ADRs) after 8 weeks of the operation were studied and evaluated again. Results: The vaginal bleeding amount and bleeding time in the observation group after the operation was less or shorter than that in the control group (P<0. 05). According to the further consultation after 8 weeks of the operation, the total clinical efficiency in the observation group was 94. 44%, which was ob-viously higher than that in the control group(75. 00%,P<0. 05). There was no obvious ADR appeared in the two groups during the treatment. Conclusion:Lacidophilin vaginal capsules combined with LEEP has reliable curative effect on cervical erosion with chronic cervicitis, which can obviously shorten the wound healing time and decrease the vaginal bleeding amount and time with high security.
ABSTRACT
Sophorae Flavescentis Radix, drying root of Sophora flavescens which is a leguminous plant of genus Robinia Linn., is rich in a variety of chemical compositions so as to have extensive biological activities. Sophorae Flavescentis Radix Gelatum (SFRG), a product of Guiyang Xintian Pharmaceutical Co., Ltd., is used to treat gynecological chronic inflammations such as cervical erosion, trichomonas vaginitis, and vaginal fungal infection. Recent reports at home and abroad suggest that in addition to the above indications, SFRG has been clinically used in adjuvant physical therapy of cervical erosion and bacterial vaginitis, senile vaginitis, mixed vaginitis vaginal inflammation, and andrology medication. This review is designed to summary these new applications of SFRG.
ABSTRACT
Objective To investigate the effect of curative and uterine cervical shaping of different loop electrosurgical excision procedure (LEEP) in treatment of chronic cervicitis.Methods Selected 369 patients with chronic cervicitis,and they were divided into shallow ring excision (SRE) group (123 patients),deep ring excision (DRE) group (123 patients) and LEEP conization (LEEPC) group(123 patients).In each group,they were divided into three subgroups according to the degree and type of erosion.The clinical efficacy of three groups were compared after treatment of 3 months.Results The recovery rate of mild uterine cervical erosion with symptom and midrange uterine cervical erosion,granular pattern uterine cervical erosion and simple uterine cervical erosion among three groups had no significant difference (P ＞ 0.05).In LEEPC group,the recovery rate of severe and mastoid uterine cervical erosion were significantly higher than those in SRE group and DRE group [80.49％ (33/41) vs.63.41％ (26/41) and 58.54％ (24/41),88.24％ (45/51) vs.71.43％ (40/56) and 74.55％ (41/55)] (P ＜ 0.05).The satisfactory rate of uterine cervical shaping among three groups had no significant difference (P ＞ 0.05).Conclusions The three kinds of LEEP have a higher satisfactory rate of uterine cervical shaping.However,different surgical procedure on different level and different type have different efficacy.Clinicians need to choose the right surgery according to the patient's condition.
ABSTRACT
Objective To compare the effects of loop electrosurgical excision procedure(LEEP knife)and microwave on cervical erosion and study the nursing effects.Methods One hundred and fifty cases of cervical erosion patients from January to December 2013 in our hospital were selected and randomly divided into observation group and control group with 75 cases in each group.Patients in the observation group were treated with LEEP knife and the control group with microwave treatment.All patients were nursed conventionally.The operative time,blood loss and efficacy of two groups were analyzed.Result Patients in the observation group had less blood loss,shorter operation time and a better curative effect than the control group with statistical difference(all P<0.05).Conclusions Compared with microwave treatment,LEEP knife can effectively treat the cervical erosion.Preparation before operation,mental care and knowledge-related nursing are critical for the smooth manipulation of the operation.
ABSTRACT
Objective To investigate the clinical effects of focused ultrasound in the treatment of cervical erosion.Methods 417 patients with cervical erosion were treated with focused ultrasound(Haijixing treatment instrument),and followed up for 3 months to observe the efficacy and adverse reactions.Results In total 417 cases,321cases(76.98％) were cured,and there were effective in 95 cases(22.78％),ineffective in 1 case(0.24％),and the total effective rate was 99.76％.No serious adverse reactions were founded.Conclusion Focused ultrasound(Haijixing treatment instrument) in the treatment of cervical erosion has obvious effect and mild adverse reactions.
ABSTRACT
Objective To observe the clinical curative effect of cervical loop electrosurgical excision procedure in treatment of patients with cervical erosion by LEEP.Methods 268 patients whose cervical erosions were above Ⅱ°were treated by LEEP,and the length of operation time,bleeding volume in the operation, amount of vaginal discharge after the operation,the length of bleeding time and cervical repair were observed.Results Follow-up was 12 weeks.262 cases (97.76% ) were cured, 6 cases (2.24% ) were effective.The bleeding amount was less than 10ml.The average surgery time was(2.62 ±0.58) minutes.18 cases(6.71% ) had the colporrhagia.No infectious case was found.Conclusion The curative effect of LEEP for cervical erosion was significant,and operation was simple and safe.LEEP was a well treatment method of cervical erosion.
ABSTRACT
Objective To investigate the clinical curative effect of dragon's blood combined with optothermal exposure in the treatment of cervical erosion. Methods 477 cases with cervical erosion were divided into two groups randomly which are 277 cases of the intervention group and 200 cases of the control group. The control group was treated with simplicity light-heat therapies and the intervention group was treated with dragon's blood oral,4 tablets each time ,3 times daily combined with optothermal exposure. The clinical outcome of two therapies were observed and compared. Results Control group :261 cases were cured(94. 3%), 11 cases were improved(3.9%) and 5 cases in vain (1.8%) The curative and total effective rate of the intervention and control group were 94. 3% and 75.0% ,98.2%and 92. 9%, respectively. The effective rate, and the vaginal secretion time and volume after operation have statistical significance (P ＜ 0.05). Conclusion The dragons invigorate blood and exhaust silt, convergent hemostatic, acetanilide detumescence, boils. Combined appicration of light-heat illuminate good curative effect, adverse reaction rate ,less in the treatment of cervical erosion.
ABSTRACT
Objective To investigate the clinical feature and strategy on diagnosis and treatment of cervical ulcer in Behcet's disease. Methods From Jan 2000 to Apr 2008,the medical documents of 6 cases with cervical ulcer in Behcet's disease were reviewed retrospectively, who were treated in No.2 hospital affiliated to Wenzhou Medical School Results (1) General information : all 6 patients with cervical ulcer were diagnosed as Behcet's disease clinically, the mean age of all patients is 33.5 years. (2) Clinical feature: the initial symptoms was oral ulcer in 5 cases and erythematic nodosum in 1 case. The typical characteristics of cervical ulcer in Behcet's disease was vaginal purulent discharge. Five among 6 cases presented it. The cervical ulcer in Behcet's disease exhibited the following features : the isolated well-defined ulcers with different size and different deep distributed on the uterine cervix, and the top of ulcer was covered by yellow discharge which was not easy to erase. The duration between the onset symptom and cervical ulcer was calculated to be 2.1 to 7 years. (3) Risk factors for cervical ulcer: operation of drawing intrauterine devices (IUD) in 2 cases, artifical abortion in 2 cases, cervical biopsy in 1 cases, and no factors in the other one case was identified. (4)Treatment: The cervical ulcer in Behcet's disease can be treated by the topical application of recombinant bovine basic fibroblast growth factor (rb-bFGF). If ulcer disease existing in other site, systemic corticosteroids management was warranted. (5) Recurrence : 1 case with recurrent disease was observed after 8 months when completing treatment, the other 5 cases did not show recurrence during 3 months-8 years follow-up. Conclusions The cervical ulcer in Behcet's disease most commonly occurred after cervical operation. The diagnosis should be derived from comprehensive symptoms analysis. The topical application of rb-bFGF on ulcer site of cervix could get satisfied outcome. When necessary, systemic corticosteroids administration could be considered.
ABSTRACT
Objective To observe therapeutic effects of compounded zedoary turmeric oil suppository com-bined with microwave therapy on cervical erosion. Methods Women with cervical erosion were randomly divided in-to two groups: single microwave therapy group (control group) and compounded zedoary turmeric oil suppository com-bined with microwave therapy group (observation group). The chnical cure rate, obvious effective rate and ineffective rate were compared between two groups. Results In mild erosion, the clinical cure rate, obvious effective rate and ineffective rate were 87.8%, 12.2% ,0 respectively in the observation group. In tbe control group were 85.7%, 14.3%,0 respectively, and there was no significant difference between them (P >0.05); In moderate erosion, were 86.1%, 12.8%, 1.2% respectively in the observation group; were 60.9%, 31.9%, 7.2% respectively in the control group and there was significant difference between them (P < 0.01); In severe erosion, were 59.4%, 34.4%, 6.2% respectively in the observation group; were 29.17%, 41.7%, 29.2% respectively in the control group, and there was significant difference between them (P < 0.05). Conclusion Single microwave therapy to the mild erosion was suf-ficient; nevertheless, compounded zedoary turmeric oil suppository combined with microwave therapy to moderate and severe erosion was better than single microwave therapy.
ABSTRACT
CONTEXT AND PURPOSE: Uterine cervical ectopy (cervical erosion) is today considered to be a physiological condition, but there still seems to be a strong tendency towards treating it. The purpose of this study was to review the medical literature for evidence regarding benefits from treating cervical ectopy. METHODS: The following databases were reviewed: Medical Literature Analysis and Retrieval System Online (Medline), Excerpta Medica Database (Embase), Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs) and Cochrane Library databases. In addition, six medical textbooks were consulted. RESULTS: The review showed that: 1) there is probably an association between ectopy and higher risk of Chlamydia trachomatis, human papillomavirus and human immunodeficiency virus infection; 4) there is probably an association between ectopy and cervical intraepithelial neoplasia; 5) there is an association between ectopy and mucous discharge and nocturia; and 6) there is no evidence of an association between ectopy and cervical cancer, or of protection against cervical cancer associated with ectopy treatment. CONCLUSIONS: 1) No data were found in the medical literature to support routine treatment for ectopy; 2) Treatment could be recommended for symptom relief, but more symptoms are attributed to ectopy than could be demonstrated in a controlled study; 3) Further studies to test the hypothesis of protection against cervical cancer associated with treatment are necessary.
CONTEXTO E OBJETIVO: A ectopia do colo do útero é hoje considerada um fenômeno fisiológico, mas parece ainda haver uma forte tendência no sentido da intervenção (tratamento). Este estudo se propõe a realizar revisão da literatura buscando evidências de benefícios conseqüentes ao tratamento da ectopia. MÉTODOS: Pesquisa nas bases Medical Literature Analysis and Retrieval Sysem Online (Medline), Excerpta Medica Database (Embase), Literatura Latino-Americane e do Caribe em Ciências da Saúde (Lilacs), Biblioteca Cochrane e seis livros especializados. RESULTADOS: A revisão mostrou que: 1) existe provavelmente associação de ectopia com infecção cervical por Chlamydia trachomatis, pelo vírus HPV e maior risco de soroconversão para HIV; 2) existe provavelmente associação entre ectopia e neoplasia intra-epitelial cervical; 3) existe associação com mucorréia e nictúria; 4) não existem evidências sobre associação entre ectopia e câncer de colo do útero nem sobre proteção contra este câncer proporcionada pelo tratamento da ectopia. CONCLUSÕES: 1) Não foram encontrados na literatura dados que justifiquem o tratamento rotineiro da ectopia; 2) O tratamento pode ser utilizado para tratar sintomas associados à ectopia, porém mais sintomas são atribuídos à ectopia do que se pôde confirmar em um estudo controlado; 3) Seriam necessários novos estudos para testar a hipótese de proteção contra o câncer de colo proporcionada pelo tratamento.
Subject(s)
Humans , Female , Adolescent , Adult , Cautery , Neoplasms, Squamous Cell/prevention & control , Uterine Cervical Erosion/surgery , Uterine Cervical Neoplasms/prevention & control , Brazil , Uterine Cervical Dysplasia/etiology , Uterine Cervical Dysplasia/pathology , Uterine Cervical Dysplasia/prevention & control , Chlamydia Infections/complications , Chlamydia Infections/pathology , Electrocoagulation , HIV Infections/complications , HIV Infections/pathology , Information Storage and Retrieval/methods , Metaplasia/pathology , Neoplasms, Squamous Cell/etiology , Neoplasms, Squamous Cell/pathology , Uterine Cervical Erosion/microbiology , Uterine Cervical Erosion/pathology , Uterine Cervical Neoplasms/etiology , Uterine Cervical Neoplasms/pathology , Young AdultABSTRACT
Objective To explore the effect and mechanism of Liq Qibei against herpes simplex virus-Ⅱ(HSV-Ⅱ) for treatment of cervical erosion.Methods Using micro-inhibition cytopathic and in vitro cell culture technique,the various concentrations of Liq Qibei in inhibiting HSV-Ⅱ proliferation and the direct virucidal effect were studied.The virus titer and virus inhibition index were taken as parameters.Results ① Virus proliferation experiment:Compared with control group,the virus titer of 1.63,0.81,0.41 mg/mL Liq Qibei group had significant difference(P2.② Direct virucidal effect of Liq Qibei:comparing with control group,1.63 mg/mL Liq Qibei in 8 h,24 h and 0.81 mg/mL-24 h groups had marked difference(P0.05).Conclusion Liq Qibei antivirus effect on HSV-Ⅱ.
ABSTRACT
Objective To explore the efficacy and value of the one-off cure of the serious cervical erosion by Microwave combined with idophor.Methods Eighty patients with serious cervical erosion enrolled in our department from 8,2003 to 10,2005 were randomly allocated to group A as test group and group B as control group.Both groups were treated with microwave.But every one or three days, cervix and vagina of group A was scrubbed by idophor.After three months,every group was re - examined to observe the efficacy and side -effect of the one-off cure.Results The one-off cure rate in group A(95%)was significantly higher than in group B(77.5%). There was a significant difference between the two groups(P＜0.05).The average days of took off scab in group A(9.66)had a signifi- cantly deeper invasion than in group B(13.87)(P＜0.05).Conclusion On cure of the serious cervical erosion by microwave combined with idophor can shorten the took off scab period and improved the one - off cure rate.The convenient method can be used widely.
ABSTRACT
The study had been conducted in 85 patients aged from 22-49, who were diagnosed as cervical erosion to find out the effect of cryosurgery method. Results: this method was effective in treating cervical erosion; 80% of the patients recovered after the 1st time treatment and 20% in the 2 nd times. The percentage of the recovery related to diameter injuries. This method did not cause any serious complications but some light complications such as disordered menstruation (17.6%), menorrhagia (11.8%), backache or lower backache (5.9%), appendage inflammation (4.7%). After the treatment, 8.2% of these cases are able to get pregnant and give birth as common
ABSTRACT
The significance of cervical erosion with benign cellular change on Papanicolaou smear has not been evaluated. A retrospective review of 430 coloscopically directed punch biopsies performed over 15 months revealed 206 cases who had a benign cellular change on cytologic smear. Of these 206 smears, 48(23%) had clear cervix without erosion, 99(48%) had mild erosion on cervix, 41(20%) had moderate cervical erosion and 18(9%) had severe cervical erosion. The false negative rate that revealed more than mild dysplasia on histologic diagnosis was 2% in patients without cervical erosion, 3% in patients with mild cervical erosion, 5 % in patients with moderate cervical erosion, and 11% in patients with severe cervical er- osion. Koilocytotic change that suggested human papilloma virus infection was 17% in each group regardless cervical erosion. In conclusion, benign cellular change on Pap smears in patients with severe cervical erosion may be associated with significant cervical cancer pathology.