Acupoint application for exogenous fever: a multi-central retrospective cohort study / 中国针灸

OBJECTIVE@#To explore the effectiveness on exogenous fever and the characteristics of effective population, as well as the specialties of prescription of acupoint application.@*METHODS@#Using the internet electronic diagnosis and treatment platform (Spring Broadcast Wanxiangyun Clinic Database, and the main TCM suitable technology promoted by this platform is acupoint application therapy), from August 24, 2020 to November 5, 2020, the patients complained with fever and diagnosed as common cold, with a record of initial visit and at least one return visit, were included as the subjects. According to whether acupoint application therapy was received or not, the subjects were divided into an exposure group (with acupoint application therapy, 26 664 cases) and a non-exposure group (without acupoint application therapy, 515 cases). Using the propensity score, the mixed factors, e.g. age and sex, were matched between the two groups. The disappearance rate of fever (within 2 days) and the time for the first fever disappearance were taken as the effect indexes. The association rules extraction was adopted to analyze the characteristics of effective population and acupoint application prescription in treatment of exogenous fever.@*RESULTS@#After propensity score matching, there were 1 229 cases in the application group and 423 cases in the non-application group. The disappearance rate of fever in the application group was 1.82 times as high as that in the non-application group (P<0.05). The time for the first fever disappearance in the application group was shorter than the non-application group (P<0.01). A total of 5 370 cases were effective with acupoint application therapy, of which, the median age was 2 years old and the proportion of children patients under 6 years old was relatively high. In the effective crowd, the most commonly-used acupoints were Shenque (CV 8), Dazhui (GV 14), Yongquan (KI 1) and Tiantu (CV 22), etc. Shenque (CV 8) and Dazhui (GV 14) were highly associated and the support was 62.57%. The most common herbal materials in the acupoint application therapy included Radix et Rhizoma Rhei, Natrii Sulfas, Radix Scutellariae, Herba Ephedrae and Radix Bupleuri, etc. Radix et Rhizoma Rhei and Natrii Sulfas were most commonly used at Shenque (CV 8) and the supports were 57.49% and 57.21% respectively. Herba Ephedrae was most commonly applied to Shenque (CV 8) and Dazhui (GV 14) and the supports were 48.21% and 43.91% respectively. Radix Bupleuri was the most common herb at Dazhui (GV 14) with the support of 46.61%. Besides, the most commonly combined western drugs included cefixime and keteling in the acupoint application therapy and the supports were 13.07% and 12.72% respectively.@*CONCLUSION@#Acupoint application is effective on exogenous fever. The common therapy refers to Radix et Rhizoma Rhei and Natrii Sulfas plaster at Shenque (CV 8), while Herba Ephedrae and Radix Bupleuri at Dazhui (GV 14).

Exploration of Chaige Jieji Decoction formula syndromes based on severe cases of critical care and its application for acute exogenous fever and nosocomial infection / 中国中药杂志

Chaige Jieji Decoction recorded in Six Books of Exogenous Febrile Disease could be used to treat exterior syndrome due to wind-cold and heat caused by stagnation. The indications of Chaige Jieji Decoction include acute exogenous febrile diseases,such as influenza,upper respiratory tract infection,nosocomial infection; symptoms and signs,such as headache,eye pain,orbital pain,dizziness; fever,cold and hot exchanges; dry mouth,thirst,cold drinks,bitter mouth,dry throat; dry nose,stuffy nose,runny nose; poor appetite,silent appetite; strong neck,stiff back; insomnia,difficulty in sleeping; cough and sputum; abdominal pain,limb twitching;slightly torrent pulse. Disease involving all three Yang channels is very common in acute exogenous febrile diseases; the pathogenesis of exogenous diseases is quite different between cases in South China and North China. Most of the exogenous diseases in North China involves all three Yang channels. Disease involving all three Yang channels is the core of the pathogenesis of Chaige Jieji Decoction syndrome,in which headache is the key indications. Chaige Jieji Decoction can not only treat exogenous diseases,but also treat nosocomial infections in critically ill patients during hospitalization. Although Chaige Jieji Decoction,Xiaochaihu-Maxing Shigan Decoction,and Xiaochaihu-Daqinglong Decoction could be used to treat disease involving all three Yang channels,there are differences in indicators among them.

Proved Case Records by Using the Modification of Guizhi Decoction plus Dahuang in the Treatise of Cold-Induced Disorders to Treat Paedi- atric Diseases / 浙江中医药大学学报

[Objective]Discussing the experiences on using the Modification of Guizhi Decoction plus Dahuang in the Treatise of Cold-Induced Disorders to treat paediatric diseases.[Methods]Selecting 4 paediatric cases that are all using Guizhi added Dahuang Tang to treat concurrent disease of Taiyang and Yangming Channels, concurrent disease of Taiyin and Yangming Channels, interior excess pattern of Taiyin which causing fever, eczema, constipation, abdominal pain,to discuss the train of thoughts in using the Modification of Guizhi Decoction plus Dahuang in the clinic.[Results] Using the Modification of Guizhi Decoction plus Dahuang in the Treatise of Cold-Induced Disorders with a flexible addition and subtraction can treat all kinds of paediatric diseases such as concurrent disease of Taiyang and Yangming Channels, concurrent disease of Taiyin and Yangming Channels, interior excess pattern of Taiyin.The 4 cases proved in this article all used the Modification of Guizhi Decoction plus Dahuang to treat paediatric exogenous high fever, eczema, constipation, abdominal pain, etc,on the basis of syndrome differentiation,using the Modification of Guizhi Decoction plus Dahuang ,or Xiaojianzhong Decoction plus Dahuang,with the addition and subtraction,to treat various of paediatric diseases caused by concurrent disease of Taiyang and Yangming Channels, concurrent disease of Taiyin and Yangming Channels, interior excess pattern of Taiyin ,and all obtained good effects. [Conclusion] Under the guidance of the six meridians syndrome differentiation,with the addition and subtraction of the Modification of Guizhi Decoction plus Dahuang,expand the scope of the application of classical prescription,and enhance the clinical effects.