1.
Journal of Pharmaceutical Practice
;
(6): 78-79, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-790298
ABSTRACT
OBJECTIVE:To study the hemorheological paramenters in rat with hepatic fibrosis. METHODS:Hepatic fibrosis in rat was induced by CCl4 treatment. Whole blood viscosity, plasma viscosity, Hematocrit(Hct) and dynamic parameters of red blood cell(RBC) were investigated. RESULTS:As compared with the normal group, the hemorheological parameters such as whole blood viscosity, plasma viscosity, Hematocrit(Hct), RBC's aggregation and rigidity were increased obviously. CONCLUSION:High blood vicosity and low RBC's deformation ability can lead to blood circulation obstacle, thus will aggravate hepatic fibrosis.