Budleja asiatica Derived Phytochemicals against Eye Disease

The secondary metabolites in the plants are used for curing various diseases. The phytochemicals present in Budleja asiaticaplant extract are traditionally used to cure Eye disease. It is caused by Haemophilus influenza, whichis a facultatively anaerobic, gram-negative pathogenic bacteria. For analysis of ligand-protein interaction, the molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate Aspararte semialdehyde dehydrogenase enzyme which is important macromolecule for the regulation of amino acid biosynthesis resulting in interrupting the life cycle of the microorganism

Dietary Very Long Chain Saturated Fatty Acids and Metabolic Factors: Findings from the Korea National Health and Nutrition Examination Survey 2013

The present study was aim to evaluate the association between very long chain saturated fatty acids (VLSFAs) and metabolic syndrome (MetS) in Korean population. The study population were recruited from the Korea National Health and Nutrition Examination Survey VI (2013). Using the cross-sectional study design, socio-demographic factors, medical history, and clinical measurements were investigated according to quartiles of VLSFAs intake. The associations between each and sum of VLSFAs intake and MetS were assessed by logistic regression. The result indicated that higher intake of VLSFAs was significantly associated with favorable metabolic status, including lower levels of circulating triglyceride (TG) (p < 0.05). Additionally, subjects with higher intake of arachidic acid and total VLSFAs were negatively associated with MetS risk compared to subjects with lower intake of those fatty acids (p < 0.05). In conclusion, dietary VLSFAs intake was associated with metabolic risk factors and lower risk of MetS in Korean population.

Chemical constituents from root barks of Ginkgo biloba (I) / 中草药

Objective: To study the chemical constituents from the root barks of Ginkgo biloba. Methods: The constituents were isolated by column chromatography and their structures were elucidated by physicochemical properties and spectroscopic analyses. Results: Thirteen compounds were isolated including four fatty acids, palmitinic acid (1), stearic acid (2), behenic acid (3), and lignoceric acid (4); one fatty alcohol, 1-heptacosanol (5); two sterides, β-sitosterol (6) and daucosterol (7); two flavonoids, genkwanin (8) and apigenin (9); and four ginkgolides, bilobalide (10), ginkgolide A (11), ginkgolide B (12), and ginkgolide C (13). Conclusion: Among them, compounds 3-5 are isolated from this plant for the first time. The results are helpful for the comprehensive utilization of the resources of the root barks of G. biloba.