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Objective To analyze TORCH infection situation in 6 027 cases of pregnant women,puerperae and neonates.Methods The TORCH IgM and IgG was detected by using ELISA for 6 027 cases of pregnant women,puerperae and neonates,and the positive rates of the antibodies to variant TORCH pathogens were analyzed.Results The positive rates of HSVⅠ-IgM,HSVⅡ-IgM,RV-IgM,TOXO-IgM and CMV-IgM were 0.02%,0.02%,0.12%,0.12% and 0.20% respectively.The positive rates of HSVⅠ-IgG,HSVⅡ-IgM,RV-IgM,TOXO-IgM,and CMV-IgM were 63.32%,13.31%,52.83%,12.68% and 58.57% respective-ly.Positive rate of CMV-IgM in neonates was higher than that in pregnant women,the difference was statistically significant(P <0.05).There were totally 28 cases of neonataes detected with acute CMV infection.Conclusion TORCH screening in pregnant women,puerperae and neonates helps the detection of infection disease in perinatal period.
ABSTRACT
Objective To investigate the serum concentration of cystatin C in puerperae and the relationship of cystatin C with e-rythrocyte count,leukocyte count,urine microalbumin and specific gravity.Methods The serum cystatin C,Cr,BUN and urine e-rythrocyte count,leukocyte count,urine microalbumin and specific gravity were detected in 232 puerperae and 200 healthy women. Multiple linear regression analysis was performed to analyze the relationship of cystatin C with urine erythrocyte count,leukocyte count,urine microalbumin and specific gravity.Results The concentration of cystatin C in the puerperal group was significantly higher than that in the normal control group(P <0.05).The concentrations of Cr,BUN in the puerperal group were significantly lower than that in the normal control group (P <0.05).The erythrocyte count and the leukocyte count,in the puerperal group were higher than those in the control group(P <0.05).The urine microalbumin was higher in the puerperal group than that in the con-trol group(P <0.05).There was no significant difference of specific gravity between them.In multiple linear regression analysis,a regression relationship was found between cystatin C(Y)and urine microalbumin(X1 )and specific gravity(X2 ).Regression relation-ship was not found between cystatin C and other indices.Conclusion Elevated serum cystatin C,together with urine microalbumin suggests early renal function change.They can be used to monitor renal function for the puerperae.
ABSTRACT
A prevalência da infecção pelo vírus linfotrópico humano de células T em puérperas do Estado de Mato Grosso, no Brasil, não é conhecida. Neste estudo transversal definiu-se a prevalência da infecção em puérperas atendidas em três maternidades públicas de Cuiabá (MT). De abril a setembro de 2006, 3.831 partos foram realizados e 2.965 puérperas foram submetidas aos testes sorológicos para o HTLV-1/2 (Enzyme Linked Immuno Sorbent Assay - ELISA e Western Blot). A idade média das mulheres participantes foi de 23,9 anos. A prevalência da infecção pelo HTLV-1/2 foi de 0,2 por cento, semelhante à observada na população geral de vários centros desenvolvidos do país. Esse achado de baixa prevalência sugere que ainda não é justificada a introdução de intervenção de saúde pública para a população de gestantes de nosso meio, visando à redução da transmissão vertical do HTLV-1/2.
The prevalence of human T-cell lymphotropic virus (HTLV-1/2) infection among puerperae in the State of Mato Grosso, Brazil, is unknown. Through this cross-sectional study, the prevalence of HTLV-1/2 infection among puerperae attended at three public maternity hospitals in Cuiabá, State of Mato Grosso, was defined. Between April and September 2006, 3,831 deliveries took place and 2,965 puerperae underwent serological tests for HTLV-1/2: enzyme-linked immunosorbent assay (ELISA) and western blot. The mean age of the women studied was 23.9 years. The prevalence of HTLV-1/2 was 0.2 percent, i.e. similar to the prevalence observed in the general population of many developed centers in Brazil. This finding of low prevalence suggests that there is still no justification for introducing public health interventions for the population of pregnant women in our setting, to reduce the vertical transmission of HTLV-1/2.
Subject(s)
Adolescent , Adult , Female , Humans , Pregnancy , Young Adult , HTLV-I Infections/epidemiology , HTLV-II Infections/epidemiology , Human T-lymphotropic virus 1 , Postpartum Period , Blotting, Western , Brazil/epidemiology , Cross-Sectional Studies , Enzyme-Linked Immunosorbent Assay , HTLV-I Antibodies/blood , HTLV-I Infections/diagnosis , HTLV-II Antibodies/blood , HTLV-II Infections/diagnosis , Human T-lymphotropic virus 1/immunology , /immunology , Prevalence , Socioeconomic Factors , Young AdultABSTRACT
In this study, IgA1 levels in the milk and serum of puerperae were compared and a correlation was established between the levels of this immunoglobulin and the occurrence of parasitism. Eighty-three paired milk and serum samples were obtained from puerperal and IgA1 levels were analyzed. In addition, the presence of intestinal parasites in stool samples from these puerperae was determined. Twelve puerperae tested positive for intestinal parasites and all their samples presented an IgA1 ELISA Index > 1. There was a correlation between serum and milk IgA1 levels and puerperae with any parasite in their stool (r = 0.6723; p = 0.0166). This finding may reinforce the importance of breast-feeding for the protection of neonates.