ABSTRACT
Background: Pregnancy may alter the course of pre-existing skin disorders and lesions occurring during pregnancy and may show alterations in their course and may have a negative effect on the pregnancy outcome. In pregnancy endocrinal changes may be associated with higher levels of estrogen, progesterone, placental hormones and activity of the fetal adrenal glands Objectives: To study clinical profile of skin changes and disorders associated with pregnancy Methods: Hospital based prospective study was carried out among 60 pregnant women with skin disorders. Detailed history was elicited regarding the skin changes and associated symptoms with regards to the onset, duration, progress and recurrence. Dermatological examination of lesions was carried out. Follow up of the patients was done to observe the course of the disease and outcome of the pregnancy. Results: Majority belonged 21-30 years (60%). Majority (55%) had onset of skin changes during third trimester. Most common physiological change seen was striae in 46.7%. Specific dermatoses of pregnancy were seen in 15%. Infections were most common seen in 45%. 6.7% of the women complained of eczema. 88.3% had skin disorders associated with pruritus. Among them most common was Dermatophyte infection in 25%. Pruritic urticarial papules and plaques of pregnancy and Prurigo gestations were most common specific dermatoses of pregnancy seen in four cases each (6.7%). Conclusion: Non-physiological skin disorders among pregnant women constituted major portion. Infections and infestations were major risk factors for skin disorders in pregnancy but their course was not altered by pregnancy. Majority of pregnant women responded well to treatment
ABSTRACT
Background: Ayurveda is a highly evolved and codified system of life and health science based on its own unique and original fundamental concepts and principles. One of them is the Paradi Gunas (properties). Paradi Gunas (properties) are ten in number and have a wide application aiming at the success of treatment in which, choice of medicine and dietary rules play vital role. For success in the treatment understanding the role and action of a medicine is important, and this can be achieved by the use of Paradi Gunas (properties). Objective: To apply the concept of Paradi Gunas (properties) on Aarogyavardhini Rasa, a ployherbo-mineral medicine during different stages of processing. Data Source: This literary review has used the data source from various online portals as well as books in Ayurveda. Conclusion: The use of Paradi Gunas was studied on the pre-processing, processing and the therapeutic stages of Aarogyavardhini Rasa and its applications were noted. This can be a primary step towards deeper understanding of its role in therapeutics.
ABSTRACT
Objective: In this study, we investigated the occurrence of skin damage following the initiation of low-dose lamotrigine.Methods: We retrospectively analyzed the incidence of skin disorders within 8 weeks of the start of lamotrigine administration, prescribing for 3 years from July 2014 to June 2016.In addition, we also confirmed the onset time of skin disorders in the low- and normal-dose groups.Results: The incidence of skin damage was 7.7 and 24.6 % in the low- and normal-dose lamotrigine start groups, respectively. The onset of skin disorders was relatively early in the normal-dose lamotrigine start group.On the other hand, no tendency was found in the low-dose lamotrigine start group because the number of cases was small.Conclusion: The initiation of low-dose lamotrigine and extension of introduction period might reduce the onset of early skin damage.
ABSTRACT
O presente artigo objetiva apresentar o desenvolvimento de um website para ser utilizado como ferramenta de ensino e orientação de pais e cuidadores de crianças com dermatite atópica (DA). O estudo foi conduzido em três etapas: a) Levantamento de informações sobre DA; b) Elaboração de roteiros para o website e; c) Desenvolvimento do website. O website foi elaborado com ilustrações, gifs, textos curtos sobre a DA e orientações sobre como instruir as crianças nas situações de tratamento de modo interativo e acessível. Espera-se auxiliar cuidadores na melhora do manejo comportamental de crianças com DA na adesão ao tratamento.
This article aims to present the development of a website to be used as a learning and guidance tool for parents and caregivers of children with atopic dermatitis (AD). The study was conducted in three phases: a) collection of data related to AD; b) preparation of scripts for the website and; c) development of the website. The website was developed with pictures, animated gifs, brief texts about AD and guidance on how to instruct children during treatment situations in an accessible and interactive way. We aim to help caregivers in the improvement of behavioral management of children with AD on adherence to medical treatment.
Este artículo objetivo presentar la construcción de un sitio web como herramienta de aprendizaje y orientación de padres y/o cuidadores de niños con dermatitis atópica (DA). El estudio fue organizado en tres etapas: a) levantamiento de informaciones acerca de la DA, b) elaboración del guión para el sitio web y c) construcción del sitio web. El sitio web fue desarrollado con ilustraciones, animaciones en formato gif, textos breves sobre la DA y orientaciones sobre cómo instruir a los niños en las situaciones de tratamiento, en un formato interactivo y accesible. Se espera auxiliar cuidadores en la mejora del manejo conductual de niños con DA en la adhesión al tratamiento.
ABSTRACT
La epidermolisis bullosa distrófica es un grupo de trastornos hereditarios de muy baja prevalencia que se caracterizan por una extrema fragilidad cutánea como consecuencia de una alteración de la cohesión de la unión epidermodérmica. Sin embargo, las manifestaciones clínicas van más allá de las lesiones cutáneas, habiéndose descrito afectación de la mayoría de aparatos y sistemas y siendo frecuente también cierto grado de desnutrición y anemia de origen multifactorial. Presentamos el caso de una paciente de 34 años, secundigesta, con epidermólisis bullosa distrófica recesiva severa, gestante gemelar bicorial y biamniótica, que seguimos durante todo el embarazo y su finalización. La baja prevalencia de la enfermedad hace que el manejo de la gestación suponga un reto para el ginecobstetra. A pesar de que los casos publicados hacen creer que la gestación no modifica el curso natural de la enfermedad, lo cierto es que se recomienda que el embarazo sea seguido por un equipo multidisciplinar. Existen publicados casos en los que se finaliza la gestación por vía vaginal, sin embargo, no existe evidencia suficiente para considerar ésta como la vía de elección.
Dystrophic epidermolysis bullosa is a group of hereditary disorders that has very low prevalence. It is characterized by an extreme cutaneous fragility as a consequence of a cohesion alteration of the epidermis and dermis junction. However, the clinical manifestations also affect other systems and organs, being able to cause malnutrition and anemia. We present the case of a 34-year-old woman affected by severe recessive dystrophic epidermolysis bullosa, with a bichorial and biamniotic twin pregnancy, whom we have followed throughout the pregnancy. The low prevalence of this disease makes the management of the pregnancy a challenge for the obstetrician. Although the published cases suggest that gestation does not modify the natural course of the disease, it is recommended that these pregnancies are monitored by a multidisciplinary team. Some published cases describe vaginal delivery. Nevertheless, it is not clear that this should be the first choice.
Subject(s)
Humans , Female , Pregnancy , Adult , Pregnancy Complications , Epidermolysis Bullosa Dystrophica/complications , Pregnancy, Twin , Pregnancy Outcome , Cesarean SectionABSTRACT
Background: The objective of the study was to find out the personal hygiene status among boys residing in social welfare hostels by class and age and type of hostel.Methods: Cross sectional study, analytical study, social welfare hostels in Tirupati town of Andhra Pradesh. Participants was 524 boys. Statistical analysis are percentages and Chi-square test.Results: The prevalence of scabies was found to be significantly higher in those children with poor personal hygiene (35.7%) compared to average level (18.8%) and good (14.4%) of personal hygiene. The prevalence of other specific morbid conditions was found to be similar in all the three levels of personal hygiene and the differences were not statistically significant.Conclusions: The prevalence of scabies was found to be significantly higher in those children with poor personal hygiene compared to average level and good of personal hygiene. In view of higher proportion of children with poor level of personal hygiene of children in scheduled tribe hostel, there is a need to sensitize and give health education on personal hygiene related diseases and take necessary preventive steps and supervision by hostel staff especially in scheduled tribe hostel. Hand washing with soap can protect about one out of every three young children.
ABSTRACT
The role of hostels in the educational advancement of backward classes is long recognized. In closed homes like hostels, the morbid conditions especially infectious diseases like skin diseases and respiratory diseases tend to rapidly spread among others and become difficult to control. There is increased nutritional demand in this age group because of pubertal changes. It has been found that several school children especially from socially backward sections of the community suffer from nutritional health problems as well as other physical health problems. We wanted to evaluate the morbidity pattern among boys residing in social welfare hostels.METHODSThis is a cross sectional, analytical study to determine the morbidity pattern among boys residing in social welfare hostels. This present study was conducted from August 2013 to July 2014 among boys residing in three welfare hostels, one each for scheduled castes, scheduled tribes and backward classes in Tirupati town.RESULTSThe common prevalent morbid conditions found were skin disorders (46.4%), nutritional disorders (43.1%), eye diseases (29.0%), respiratory diseases (15.3%) gastrointestinal diseases (13.6%), ENT diseases (9.5%,), musculoskeletal conditions (1.0%), and other diseases (5.7%).CONCLUSIONSHealth education and increasing the nutritional supplements improve the health of children with regard to personal hygiene and common diseases. Provision of necessary materials like soaps, oils etc., under supervision of hostel staff will go a long way in controlling these infections.
ABSTRACT
Background: Periodic auditing of prescriptions in terms of drug utilization study is an important tool to enhance the efficacy of the treatment, to decrease the risk of the adverse effects, to give cost-effective treatment and to provide useful feedback to the clinician. Prevalence of dermatological diseases is very high throughout the world, and in day to day practice, a quarter of the cases are related with dermatological manifestations. In studies conducted in the Out Pa-tient Department (OPD) of dermatology in North Palestine and Western Nepal, irrationalities in the prescriptions have been reported. Aim: To study the drug utilization pattern for skin diseases in dermatology OPD at tertiary care hospi-tal of Western Maharashtra. Methodology: The retrospective analysis of dermatology OPD records of 6 months (1stMarch 2018-31stAugust 2018) was carried out during the study period (1stSeptember 2018 to 30thNovember 2018). The proforma for collecting data was designed. Demographic details, diagnosis and treatment given for each patient were recorded. The data collected was condensed, and the master chart was prepared for data analysis. Result: During the study period, a total of 3869 patient’s case records were studied and analysed. A maximum number of patients (26.5%) found in the age group 31-40 years, followed by 23.5% of patients in the age group 21-30 years. Fungal in-fection was found in 39.6 % of patients followed by acne in 14.2% patients and eczema in 9.1% of patients. Drugs most commonly prescribed were antihistaminics (45.02%) followed by antifungal (39.6%) and steroids (27.8%). Levocetirizine (74.07%) and hydroxyzine (16.5%) were the most commonly prescribed antihistaminics. Itraconazole (58.17%) and Griseofulvin (24.67%) were the most commonly used oral antifungal drugs. Miconazole (73.73%) was the most commonly used topical antifungal drug, followed by ketoconazole (12.45%). Among steroids, prednisone (52%) and betamethasone (38.05%) were the most commonly used steroids by oral route while clobetasol (68.09%) and mometasone (19.5%) were the most commonly used steroids by topical route. Our study revealed that the per-centage of drugs prescribed from the WHO essential drug list was only 23.87%. Drugs which prescribed by the gener-ic names were less than <1%. Conclusion:Treatment protocols used in the management of skin disorders were near to the standard guidelines.
ABSTRACT
Introduction: Skin disorders are common in children but havenot been regarded as a public health problem even though theyput a large burden on health care systems worldwide. Aboutone-third of children in India are affected by skin disorders atany given time. Climatic factors, poor hygiene, poor accessto water, household overcrowding and close contact lead tothis high prevalence. However there is a relative paucity ofdata in comparison to this high prevalence. Study objectivewas to determine the prevalence and pattern of skin disordersamongst school going children aged 6 to 17 years in ruraland urban Jaipur and their nutritional, socio-economic andstandard of sanitation correlates.Material and Methods: Descriptive cross-sectional studycarried out in 410 children aged 6-17 years from ten randomlyselected schools, five rural and five urban, in Jaipur from 1stJanuary 2017 to 30th June 2018. Detailed history includinggrading of socioeconomic status and standard of sanitation aswell as physical examination were done with due regard toprivacy. Clinical diagnosis was made.Results: The prevalence of skin disorders was found to be48.3%, more in girls (59.6%) and more in rural areas (58.1%).Seborrhoea capitis (15.4%) was the most common followedby Acne vulgaris (13.2%), Pityriasis alba (4.4%), Tinea (alltypes) (3.9%), Pediculosis capitis (3.2%), and Furunculosis,Scabies and Pityriasis versicolor (<2% each). Prevalence hada significant correlation with level of sanitation whereas notwith literacy of parents, socioeconomic status (Kuppuswamyscore) and type of school. Only one fourth of symptomaticchildren took treatment.Conclusion: High prevalence of skin disorders exists inschool-going children of Western India, especially noninfectious dermatosis. Rural residence and level of sanitationare significant attributes.
ABSTRACT
Orento is generally used for upper gastrointestinal symptoms. We have used orento for various diseases based on “upper heat and middle cold”. As a result of the evaluation of 30 responders to orento, the most frequent sign of “upper heat” was “yellow tongue coating” (29/30 responders), while the most frequent sign of “middle cold” was “preference for warm foods and beverages” (27/30 responders). Compared with the non-responder group, the responder group showed significantly higher frequencies of “gastrointestinal cold”, which is the sum of “preference for warm foods and beverages” and “aggravation of gastrointestinal symptoms by cold foods and beverages” (29/30 responders, p = 0.047), and “upper/lower gastrointestinal symptoms” (29/30 responders, p = 0.014). These results suggest that “yellow tongue coating” is the most important sign for “upper heat” while “gastrointestinal cold” is the most important sign for “middle cold”. As Kampo patterns for orento, gastrointestinal symptoms often occur, but there is a possibility of upper or lower gastrointestinal symptoms, skin disorders, and sleep disorders.
ABSTRACT
Ozone was discovered in the mid-nineteenth century and is proven to have many therapeutic effects,including its common application as a disinfectant to kill microorganisms in various conditions.Ozone therapies have been utilized for various purposes ever since it was discovered.Extensive studies over a century have verified its therapeutic effects,consistency,and safety with minimal and preventable side effects in medical care.Emerging evidence revealed that ozone also plays important roles in the management and prevention of various skin disorders including infectious skin diseases,skin related allergic diseases,erythema scaly diseases,wound healing and ulcer recovery.Herein,the author now summarizes the recent clinical applications of ozone therapy in dermatology and provide commentary on what we have learned in our practice.Our focuses are the efficacy and safety of ozone therapies as well as the application prospects of ozone on various skin disorders.In addition,the author discusses the potential mechanisms involved in ozone therapy and the efforts we should make for.
ABSTRACT
Diabetes mellitus (DM) is a metabolic disease characterized by relative or absolute insulin deficiency. The hyperglycemic state of DM leads to changes in practically every cell type and organ of the human body. As skin changes can manifest before onset of DM, they might have diagnostic relevance. Some skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations, and diabetic foot, which can be associated with significantly increased morbidity and mortality of DM patients. Disease control, early-stage treatment (e.g., skin hydration, orthotic devices), and awareness of skin disorders can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients can help to improve the quality of life of them. The purpose of this study is to review the literature to evaluate the main clinical characteristics and complications of skin disorders in diabetic patients.
Subject(s)
Humans , Diabetes Mellitus , Diabetic Foot , Human Body , Insulin , Metabolic Diseases , Mortality , Quality of Life , Skin , UlcerABSTRACT
AbstractBier spots are asymptomatic, small, irregular, hypopigmented macules characterized by a normal histological appearance, which are usually found on the arms and legs of young adults. We describe the simultaneous presence of Bier spots in two siblings. This finding is unusual since, to the best of our knowledge, concurrent familial cases have never been reported in the literature.
Subject(s)
Adult , Female , Humans , Arm/pathology , Hypopigmentation/pathology , Siblings , Skin/pathologyABSTRACT
Antecedentes. El objetivo de este estudio fue determinar la prevalencia de dermatosis pediátricas en Diyarbakir, provincia ubicada en la región sudeste de Turquía. Materiales y métodos. Este fue un estudio transversal realizado en abril de 2008 en alumnos que asistían a ocho escuelas primarias públicas de Diyarbakir seleccionadas al azar. Se examinó a los alumnos y se les administró un cuestionario para determinar el nivel socioeconómico y las características sociodemográficas. Resultados. Los dermatólogos evaluaron, en total, a 1932 alumnos. De ellos, 953 (49,32%) eran niñas, con una media de edad de 11,06 ± 2,13 años (rango: 6-17 años). La prevalencia puntual global de trastornos de la piel fue del 59,1%. En esta muestra, 776 niños (40,2%) tenían solamente una enfermedad de la piel, mientras que 299 (15,5%) tenían dos, y 67 (3,5%), al menos tres. La prevalencia puntual de los trastornos de la piel fue del 33,1% en los alumnos de primer grado y del 78,9% en los alumnos de octavo grado (p < 0,05). Las enfermedades de la piel más frecuentes fueron en primer lugar el eccema (32,8%), seguido de los trastornos de la pigmentación (17,2%), las infecciones cutáneas (13,4%), los trastornos del cuero cabelludo (10,1%) y el acné vulgar (9,6%). Las infecciones cutáneas, los trastornos de la pigmentación, los trastornos del cabello y del cuero cabelludo y el acné vulgar fueron mucho más frecuentes en las niñas que en los varones (p < 0,05). Además, las infecciones cutáneas fueron mucho más habituales en los alumnos pupilos que en los medio pupilos (p < 0,05). Conclusión. Los trastornos de la piel afectaron al 59,1% de los niños estudiados, y se observaron con mayor frecuencia en las niñas y en los pupilos. Es necesario prestar mayor atención a estos grupos a la hora de formular medidas preventivas.
Background. The purpose of this study was to determine the prevalence of childhood dermatoses in Diyarbakir, which is located in the southeastern region of Turkey. Material and Method. This cross-sectional study was carried out in April 2008 among students of eight randomly selected public primary schools in Diyarbakir. Students were examined and questionnaire was applied to determine socioeconomic levels and socio-demographic features. Results. A total of 1932 students were examined by dermatologists. Nine hundred and fifty three (49.32%) girls, mean age was 11.06±2.13 (range 6-17). The overall point prevalence of skin disorders was 59.1%. Among this sample 776 children (40.2%) had only one skin disease whereas 299 (15.5%) had two and 67 (3.5%) had at least three. The point prevalence of skin disorders was 33.1% among students in grade 1 and 78.9% among students in grade 8 (p<0.05). The most common skin disease was eczema (32.8%), followed by pigmentation disorders (17.2%), skin infections (13.4%), scalp disorders (10.1%) and acne vulgaris (9.6%). Infectious skin problems, pigmentation disorders, hair and scalp disorders and acne vulgaris were more common among girls compared to boys (p<0.05). In addition, infectious skin problems were more common among boarders (p<0.05) compared to day students. Conclusion. Skin disorders affected 59.1% of the studied children. Skin disorders were more common among girls and boarders in this study, this group of children should be given specific attention in formulating preventive measures.
Subject(s)
Adolescent , Child , Female , Humans , Male , Skin Diseases/epidemiology , Cross-Sectional Studies , Prevalence , Schools , Turkey/epidemiologyABSTRACT
Dermatopathology involves study of the microscopic morphology of skin sections. It mirrors pathophysiologic changes occurring at the microscopic level in the skin and its appendages. Sometimes, we come across certain morphologic features that bear a close resemblance to our physical world. These close resemblances are referred to as "appearances" in parlance to dermatopathology. Sometimes, these "appearances" are unique to a certain skin disorder and thus help us to clinch to a definitive diagnosis (e.g., "tadpole" appearance in syringoma). However, frequently, these appearances are encountered in many other skin conditions and can be therefore be misleading. In this paper, we attempt to enlist such "appearances" commonly found in the dermatopathologic literature and also enumerate their differential diagnoses.
ABSTRACT
La asociación de psoriasis y vitiligo es un evento bien documentado, con una incidencia del 3%, según diferentes series de casos, aunque no hallamos trabajos de superposición de ambas enfermedades siguiendo las líneas de Blaschko, en la literatura revisada por nosotros. Presentamos el caso de una mujer de 47 años de edad con lesiones de vitiligo en rostro y en abdomen, desde la infancia, que se distribuyeron sobre las líneas de Blaschko; después de 30 años aparecieron placas eritematoescamosas sobre las manchas acrómicas del abdomen, que clínica e histopatológicamente correspondieron a psoriasis y mejoraron parcialmente con fototerapia UVB de banda estrecha. La psoriasis y el vitiligo son entidades multifactoriales, poligénicas, que pueden exhibir patrones de mosaicismo cutáneo. Se han planteado algunas teorías para explicar este fenómeno, pero todavía no son conocidos todos los factores que influyen en este tipo de presentación.
The association of psoriasis and vitiligo is a well documented event, with an incidence of 3% according to different case series, but reports of an overlap of both diseases following Blaschko lines were not found in the reviewed literature. We present the case of a 47 years old woman with vitiligo lesions in the face and abdomen, starting since childhood, distributed over the Blaschko lines; thirty years later erythematous and squamous plaques appeared over the achromic macules of the abdominal region which were clinically and histopathologically compatible with psoriasis and improved partially with narrow band UVB phototherapy. Psoriasis and vitíligo are multifactorial and polygenic skin disorders that can show patterns of cutaneous mosaicism. Some theories have tried to explain this phenomenon, but the factors that influence this presentation are still unclear.
ABSTRACT
BACKGROUND: Skin disorders are common in human immunodeficiency virus (HIV)-infected patients in Korea. However, introduction of highly active antiretroviral therapy (HAART) has changed the skin manifestations of HIV infection. OBJECTIVE: We evaluated the frequency of skin disorders and their immune status using CD4+ T lymphocyte counts in HIV infected patients. METHODS: A retrospective study of 134 HIV-infected patients who visited in our clinic was carried out from September 2008 to July 2011. All subjects underwent complete physical examination to detect their skin disorders as well as necessary diagnostic procedures by consultation with the dermatologist. RESULTS: Tinea infection (including tinea corporis, tinea pedis and onychomycosis) was the most common skin disorder identified. Patients with a CD4+ T lymphocyte count of less than 200 cells/mm3 showed a significantly higher prevalence of syphilis, oral candidiasis and drug eruption compared with patients with a CD4+ T lymphocyte count of over 200 cells/mm3. CONCLUSION: Numerous skin disorders were demonstrated in HIV-infected patients. Among them, tinea infection was the most common skin manifestation in 134 HIV-infected patients. Moreover, Syphilis, oral candidiasis and drug eruption were associated with low CD4+ T lymphocyte counts. Further evaluation is necessary to confirm the trend towards changes in skin manifestations in HIV infected patients.
Subject(s)
Humans , Antiretroviral Therapy, Highly Active , Candidiasis, Oral , Drug Eruptions , HIV , HIV Infections , Korea , Lymphocyte Count , Lymphocytes , Physical Examination , Prevalence , Retrospective Studies , Skin Manifestations , Skin , Syphilis , Tinea , Tinea PedisABSTRACT
La terapia antioxidante con Vimang en la atención primaria de salud constituye una posible alternativa para el tratamiento eficaz, adyuvante o no, de enfermedades relacionadas con el estrés oxidativo o componentes de dolor e inflamación. Se muestra los resultados de estudios clínicos con Vimang en la atención al adulto mayor, el tratamiento de la displasia de mamas, leve o moderada, y el tratamiento de dermatopatías, a partir de experiencias etnomédicas publicadas con anterioridad. En la atención al adulto mayor (n = 31, tabletas Vimang, 300 mg) mejoró, en ocho de nueve indicadores evaluados de la calidad de vida (Cuestionario de Salud SF-36), la autopercepción del estado de salud de los ancianos; el indicador más significativo fue el dolor corporal. En la terapia de la displasia de mamas (n = 100, tabletas Vimang, 300 mg) se demostró una eficacia mayor al 85 por ciento, con resultados similares o superiores a la vitamina E. En el tratamiento de enfermedades de la piel (n = 590, crema Vimang, 1,2 por ciento), se observó mejoría en 86,8 y 96,7 por ciento de los pacientes tratados por inflamación y dolor, respectivamente, y más del 90 por ciento fueron curados de forma total o parcial. Los resultados más relevantes se obtuvieron en la recuperación del color de la piel en melasma del embarazo y pitiriasis versicolor, (52 pacientes), procesos infecciosos (53 pacientes), micosis (169 pacientes). No se observaron reacciones adversas ni signos de toxicidad durante el tratamiento.
Antioxidant therapy with Vimang in primary health care is a possible alternative for the effective treatment, either adjuvant or not, of diseases related to oxidative stress, pain and inflammation. The results of clinical studies with Vimang on the elderly, breast dysplasia (mild or moderate) and skin diseases were shown taking into account previously reported ethnomedical experience. On elderly subjects (n=31 , 300mg Vimang tablets), the self perception of their health status improved in 8 of 9 evaluated parameters of life quality, being body pain the most significant (health questionnaire SF-36). In the treatment of breast dysplasia (n=100, 300mg Vimang tablets), the efficacy was over 85 percent, with similar or higher results than vitamin E. In treating skin diseases (n=590, 1.2 percent Vimang cream), 86.8 percent and 96.7 percent of patients treated because of inflammation and pain improved their condition whereas over 90 percent of patients completely or partially recovered. The most relevant results were seen in the recovery of skin pigmentation in pregnancy melasme and pitiriasis versicolor (52 patients), infectious processes (53 patients), and mycosis (169 patients). Neither adverse reactions nor toxic signs were observed in the treatment.
ABSTRACT
Several physiological skin changes such as vernix caseosa, cutis marmorata, physiologic desquamation, and sebaceous hyperplasia have been described in the neonatal period. There are also clinical characteristics of skin peculiar to neonate and infancy. Skin disorders observed during neonatal and infancy period can be divided into transient skin lesions, birth marks, and other diseases. Transient skin lesions include milia, sebaceous gland hyperplasia, erythema neonatorum, transient neonatal pustular melanosis, and acne neonatorum. Nevocellular nevus, mongolian spot, vascular malformation, hemangioma, epidermal nevus, and sebaceous nevus belong to birth marks. There are several common skin diseases such as miliaria, diaper dermatitis, atopic dermatitis, seborrheic dermatitis, and cutaneous candidiasis.