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Background: To measure neck circumference and waist circumference, to compare it between normal and overweight/obese adolescents and to validate these with body mass index. Methods: A cross-sectional study was conducted in 500 school going children/adolescents. Body mass index, waist circumference and neck circumference were measured. Independent samples t-test and Pearson’s correlation were used as tests of significance to analyse quantitative data. Results: A positive correlation of neck circumference and waist circumference with body mass index was observed. The neck circumference and waist circumference in overweight/obese adolescents were significantly higher than adolescents with normal body mass index (P<0.001). Area under curve of waist circumference was more than area under curve of neck circumference. Cut off value of neck circumference for screening adolescent obesity in boys and girls were 30.73 cm, and 29.73 cm, respectively, and waist circumference cut off value were 70.73 cm for boys and 69.23 cm for girls at fairly good levels of sensitivity and specificity. Conclusion: Neck circumference and waist circumference may be used in clinical practice and epidemiological studies as an index of overweight/obesity among school-going adolescents.
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Background: Obesity is a major modifiable cardiovascular risk factor as studied by American Heart Association. Aim of present study was to determine the prevalence of generalised and central body obesity among Medical Students and association of obesity measured by body mass index (BMI) and waist circumference (WC) with health risk factors. Material and methods: The present study was conducted on 200 medical students including 102 males and 98 females in the age group of 18-23 years in the Department of Physiology, Govt. Medical College, Amritsar. For generalised obesity (BMI> 25 kg/m2 and abdominal or central obesity (WC 94>cm in males and 80 >cm in females) were used. Results: The prevalence of generalised obesity in males and females was 75.51% (males 50.0%, females 25.51%) and abdominal or central obesity 82% (males 14% and females 68%). Isolated generalised obesity (BMI increased and WC normal) in males and female was 62.96% and 37.04% and isolated abdominal obesity (WC increased and BMI normal) in males and females 17.28% and 82.72%. Combined obesity (BMI and WC both increased) in males and females 40.12% and 59.88%. Conclusion: Prevalence of combined obesity was found high among both sexes. While isolated generalised obesity was more common in males and isolated abdominal obesity more common in females. However, these prevalence rates vary markedly depending on cut points used. WC is a better marker of obesity related risk than BMI.
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Objective To investigate the effect of acarbose on waist circumference (WC) in patients with IGR. Methods A total of 46 subjects with IGT (2 hPG>7.8 mmol/L) were selected in this study. All the subjects were given diet and exercise treatment for half a month and then treated with acarbose for 3 months in combination with life style modification. Self-paired method was adopted to compare islet βcell function and WC before and after the treatment. Results After acarbose treatment for 3 months ,islet βcell function were markedly improved. Insulin secretion of Fins and 2 hIns decreased ,early insulin secretion index (ΔI30/ΔG30 ) significantly increased ,and BMI and WC were reduced significantly (P<0.05) . Multiple regression analysis showed that there was correlation between WC and TG ,insulin resistance index (HOMA-IR) and islet β-cell function index (HOMA-β) (P< 0.05). Conclusion Acarbose in combination with life style modification can improve islet β-cell function in patients with IGR and reduce WC and abdominal fat accumulation as well.
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INTRODUCTION: Adipose tissue exclusively secretes adiponectin, a 244–amino-acid protein that regulates themetabolism of lipids and glucose and circulates quite abundantly in plasma. Adiponectin were still stronglyassociated with an increased diabetes risk in men; but the association for women was no longer statisticallysignificant. Adiponectin decreases insulin resistance and body weight by increasing lipid oxidation in muscleand other organs such as the pancreas and liver.GOAL: To define of adiponectin level in aging man living in Ulaanbaatar city.MATERIALS AND METHODS: Randomly selected 84 men aged 35-90 years old were involved to this study. Veinblood were collected, the serum were separated and were frozen until assayed by immunosorbent assay.Morning baseline adiponectin were determined in the sera. We used ELISA kit from Mesdia company (Korea).RESULT AND DISCUSSION: Average age of all participants was 56.82±12.55 years and was divided in three agegroups: 35-60 (31.1%), 61-74 (10%), 74-90 (5.55%). Levels of adiponectin were inversely associated with BMI(r=-0.103), WC (r=-0.173), and TG (r=0.143) and directly associated with age and HDL-C (r=0.117, p<0.001).All people were divided by NCEP criteria in two groups: metabolic syndrome group and healthy control group.Average adiponectin level in metabolic syndrome group was 4.83±7.10 ug/ml, in healthy group it was 5.71±7.53ug/ml, which shows that adiponectin level is significantly lower in people with metabolic syndrome.CONCLUSION: Adiponectin level was lower in people with metabolic syndrome and it has inverse correlation withwaist circumference.
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INTRODUCTION: Main reasons of metabolic syndrome are obesity and overweighing, which are becoming a global worldwide problem. Obesity is both a prevalent condition worldwide and a well-known, modifiable risk factor for various diseases, including diabetes. In a recent review article, waist circumference (WC) and body mass index (BMI) were reported as established risk factors for diabetes. GOAL: To define the prevalence of metabolic syndrome among Mongolian aging man living in Ulaanbaatar city MATERIALS AND METHODS: Randomly selected 180 men aged 35-90 years old were involved to this study. All were informed and written consent was given by each individual. The metabolic syndrome was defined by NCEP definition: high blood pressure, high waist circumference, higher fasting sugar, triglyceride and HDL-cholesterol. Anthropometric parameters like waist circumference (WC), weight, height, blood pressure and blood chemical parameters like glucose, triglyceride (TG), HDL-cholesterol (HDL-Ch) were measured by automatic biochemical analyzer. RESULT AND DISCUSSION: Average age of all participants was 56.82±12.55 years and was divided in three age groups: 35-60 (n=112), 61-74 (n=47), 74-90 (n=17). The characteristics of participants are shown Mongolian men in 38.8 % (70) of all participants had a metabolic syndrome and in compare to T.Baysgalan’s study, implemented in 2007 was higher. In our opinion it depends on our study participant’s age, because in our study number of elderly were predominating than mentioned survey. Waist circumference in metabolic syndrome group is higher than in healthy control group (p<0.05). Triglyceride level does not change with aging, but in our study participants, the TG level was negatively correlated with aging in metabolic syndrome group (r = -0.307). HDL-cholesterol is abundantly circulating molecule in human plasma and shows anti-atherogenic effect. In our participants HDL-Ch decreases with aging (r=-0.174). CONCLUSION: Our pilot study present that metabolic syndrome prevalence reaches 38.8% of total aged, male participants, and it is leads to implement and provide an investigation in large range, including urban and rural areas of the country.