ABSTRACT
Objetivos: O caso descrito a seguir busca incentivar a suspeição do médicofrente a um provável diagnóstico de Esclerose Concêntrica de Baló (ECB). Métodos: Relato de caso associado à revisão da literatura científi ca a partir artigos publicados sobre o tema. Resultados: Há grande difi culdade na determinação da etiopatologia daECB, já que há amplas áreas de desmielinização do sistema nervoso central (SNC) que podem ser observadas em várias doenças neurológicas. A RNM faz grande suspeição diagnóstica, mas a confi rmação só é realmente obtida através de biópsia cerebral...
Goals: The case described forward search to motivate the medical suspicionin front of a probable diagnose of Balos Concentric Sclerosis (BCS) establishing a routine diagnostic. Methods: Case report with cientifi c review of articles published about the subject. Results: It is really diffi cult to determine the BCSs etiology-fi siopathology because of thedifuse demyelinatings areas of the central nervous system (CNS) that are seen in a variety of CNSs diseases. Magnetic resonance (MR) is very important to the diagnosis of BCS, butthe diagnosiss key is the brain biopsy. The therapy consists of high dose of steroidals being controled by magnetic resonance imaging...
Subject(s)
Humans , Diffuse Cerebral Sclerosis of Schilder/diagnosis , Multiple Sclerosis/etiologyABSTRACT
We report a 50 years old woman admitted to the hospital due to progressive dysphagia and disarthria of there weeks duration. On admission a right hemiparesis was noted. CSF examination showed a protein of 9 mg/dl and no cells. A brain CAT scan showed rounded bilateral subcortical frontoparietal hypodense zones peripheral contrast material enhancement. Pseudobulbar palsies and hemiparesis worsened and the patient required nasoenteral feeding. She was discharged after four months, with severe dissabilities, with the diagnosis of Balo concentric, a progressive demyelinating disease
Subject(s)
Humans , Female , Middle Aged , Diffuse Cerebral Sclerosis of Schilder/diagnosis , Scleroderma, Systemic/diagnosis , Dysarthria/complications , Tomography, X-Ray Computed/methods , Deglutition Disorders/complicationsABSTRACT
La leucodistrofia cavitaria sudanofílica constituye un trastorno raro de la sustancia blanca cerebral, el cual se caracteriza clínicamente por sordera, retardo mental, trastornos de conducta y afectación de tractos largos descendentes. Desde el punto de vista neuropatológico, los rasgos resaltantes son extensa desmielinización central subcordial y profunda, conspicua astrocitosis y macro y microcavitación. Se describe el caso de un paciente masculino de 34 años de edad, con antecedentes personales y familiares, rasgos clínicos y hallazgos neuropatológicos consistentes con leucodistrofia cavitaria sudanofílica. Hasta donde alcanza nuestro conocimiento, en Venezuela no han sido publicados casos de esta inusual entidad nosológica