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Indian J Physiol Pharmacol ; 1992 Apr; 36(2): 127-9
Article in English | IMSEAR | ID: sea-107660

ABSTRACT

Protective effect of Withaferin-'A' against CCl4 induced hepatotoxicity has been assessed and the compound at 10 mg/kg dose was found to possess significant protective effect. A comparison of this protective effect with that of hydrocortisone showed it to be as effective as hydrocortisone dose per dose.


Subject(s)
Alkaline Phosphatase/blood , Animals , Blood Proteins/analysis , Carbon Tetrachloride/toxicity , Drug Interactions , Ergosterol/administration & dosage , Female , Hydrocortisone/administration & dosage , Liver/drug effects , Liver Diseases/chemically induced , Male , Rats
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