ABSTRACT
Chlamydia trachomatis is a common cause of sexually transmitted disease which can cause severe consequences. Effective prevention requires knowledge of prevalence of infection in order to target interventions in a cost-effective manner. To determine the prevalence of chlamydial infection in Mashhad, northeastern Islamic Republic of Iran, this study was performed among male patients with urethritis. Urethral discharge was collected from 150 patients. Cell culture was established for diagnosis of Chlamydia in genital specimens. Cell culture showed that 9.3% of patients in this study were infected with Chlamydia. This study provides strong evidence that prevalence of Chlamydia in our region is quite high, which necessitates screening and treatment for the infection
Subject(s)
Humans , Male , Genitalia, Male/pathology , Genitalia, Male/microbiology , Prevalence , Chlamydia trachomatis , Urethritis/microbiology , Chlamydia Infections/prevention & control , Early Diagnosis , Age Distribution , Chlamydia Infections/diagnosisABSTRACT
Se estudiaron 100 pacientes mediante un estudio prospectivo y transversal, de enero a diciembre de 1994 con el objetivo de conocer la prevalencia de infección por virus del papiloma humano en genitales masculinos. Los pacientes se estudiaron mediante historia clínica, revisión del área genital con colposcopio posterior a la aplicación de ácido acético al 5 por ciento, toma de biopsia de la región sospechosa, y estudio histipatológico. La edad de los pacientes fue de un rango de 16 a 71 años, con un promedio de 34.8 años. La edad de inicio de la vida sexual activa fue de un rango de 12 a 27 años, con un promedio de 17 años. Por lo menos el 41 por ciento de los pacientes habían tenido relaciones sexuales con prostitutas. El 26 por ciento contaba con antecedente de enfermedad de transmisión sexual. El 9 por ciento de los pacientes refería haber tenido solo una compañera sexual. El 82 por ciento fueron positivos a infección por virus del papiloma humano
Subject(s)
Adolescent , Adult , Middle Aged , Humans , Male , Biopsy , Colposcopy/statistics & numerical data , Condylomata Acuminata/diagnosis , Condylomata Acuminata/etiology , Genitalia, Male/microbiology , Papillomaviridae/isolation & purification , Sexually Transmitted Diseases/diagnosis , Sexually Transmitted Diseases/microbiologyABSTRACT
A biotin-streptavidin enzyme-linked immunosorbent assay (B-SA ELISA) was evaluated for detection of herpes simplex virus (HSV) in clinical specimens which were cervico-vaginal swabs from 205 asymptomatic women and swabs from the genital lesions of 163 suspected patients. All specimens were also subjected to a conventional virus isolation in cell culture. A blocking B-SA ELISA had 100% specificity and 98% sensitivity compared with viral isolation from patients, but had only 40% sensitivity using specimens from asymptomatics. The conventional B-SA ELISA might also be used; it gave results corresponding to B-SA ELISA blocking test except for a single specimen which was considered a false positive.