1.
Rev. Soc. Bras. Med. Trop
;
52: e20190156, 2019. graf
Article
in English
| LILACS
| ID: biblio-1041580
ABSTRACT
Abstract INTRODUCTION: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host. METHODS: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. RESULTS: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. CONCLUSIONS: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
Subject(s)
Humans , Animals , Male , Female , Rodentia/parasitology , Rocky Mountain Spotted Fever/prevention & control , Gonadotropin-Releasing Hormone/immunology , Contraception, Immunologic/veterinary , Vaccines, Contraceptive/administration & dosage , Ticks/microbiology , Brazil , Rocky Mountain Spotted Fever/transmission , Population Control/methods , Contraception, Immunologic/methods
2.
Article
in English
| IMSEAR
| ID: sea-110991
3.
Indian J Exp Biol
;
1992 Nov; 30(11): 947-50
Article
in English
| IMSEAR
| ID: sea-62528
4.
Indian J Exp Biol
;
1988 Nov; 26(11): 905-6
Article
in English
| IMSEAR
| ID: sea-56412
5.
Indian J Exp Biol
;
1988 Nov; 26(11): 819-23
Article
in English
| IMSEAR
| ID: sea-62260
Subject(s)
Animals , Antibodies, Monoclonal/immunology , Dogs , Estrus , Female , Gonadotropin-Releasing Hormone/immunology , Immunization, Passive , Ovulation , Rats
6.
Indian J Exp Biol
;
1988 Apr; 26(4): 252-4
Article
in English
| IMSEAR
| ID: sea-57132
7.
Indian J Exp Biol
;
1986 Jan; 24(1): 19-22
Article
in English
| IMSEAR
| ID: sea-62166
8.
Indian J Exp Biol
;
1986 Jan; 24(1): 15-8
Article
in English
| IMSEAR
| ID: sea-61614
9.
Indian J Exp Biol
;
1985 Dec; 23(12): 667-72
Article
in English
| IMSEAR
| ID: sea-59555
Subject(s)
Animals , Dogs , Estrogens/physiology , Estrus , Female , Gonadotropin-Releasing Hormone/immunology , Immunization , Ovary/physiology
10.
Indian J Exp Biol
;
1985 Dec; 23(12): 673-5
Article
in English
| IMSEAR
| ID: sea-62352