Hallazgos endoscópicos en pacientes con hemoptisis y radiografía de tórax normal / Endoscopics findings in patients with hemoptysis and normal chest X-ray

La hemoptisis se define como la emisión de sangre proveniente de la región subglótica, habitualmente por el mecanismo de la tos. Se realizó un estudio observacional descriptivo, de corte transversal y retrospectivo a los pacientes con hemoptisis y radiografía de tórax posteroanterior normal a los cuales se les realizó broncoscopia en el período de tiempo de enero de 1999 a enero del 2009 en el Hospital Neumológico "Benéfico Jurídico", con el objetivo de identificar los hallazgos endoscópicos obtenidos a través de este proceder. Se revisaron los libros de registros de broncoscopias y de los resultados de informes de Microbiología y Anatomía patológica del centro. La población estuvo compuesta por 197 enfermos y la muestra quedó constituida por 67 pacientes. El análisis estadístico se realizó en el programa EPIDAT versión 3.0. Se utilizaron medidas de resúmenes para variables cuantitativas, media y desviación estándar (DE), en todas las variables se usó la frecuencia absoluta y los porcentajes con sus respetivos intervalos de confianza del 95 por ciento. Predominó el sexo masculino con un total de 45 pacientes (67,2 por ciento) y el grupo de edad entre los 40-49 años. En 70,1 por ciento de los casos se observó signos inflamatorios, en 16 enfermos se obtuvo crecimiento de gérmenes patógenos y en 17 (25,3 por ciento) se confirmó el diagnóstico de enfermedad neoplásica por biopsia y/o cepillado bronquial.

Hemoptysis is defined as the outcomming of blood from the subglotic region, habitually by the mechanism of cough. A cross- sectional, retrospective, transverse and descriptive study was carried out in patients with hemoptysis and normal PA thorax's x-ray. To whom were practiced bronchoscopy in the "Benéfico Jurídico" Neumologyc Hospital from January 1999, to January 2009, with the purpose of identifing the endoscopyc discoveries obtained through this procedure. The information was obtained from the bronchoscopy, microbiology and pathological Anatomy records of this center. The population was composed by 197 sick people and the sample was constituted by 67 patients. The statistical analysis was carried out in the program EPIDAT version 3.0. Mediates and standard (SD) were used for quantitative variables and absolute frequency and the percentages with their respective intervals of trust of 95 percent were used in all the variables. The masculine sex prevailed with a total of 45 patients (67.2 percent) and the age group was among 40-49 years old. In 70.1 percent of the cases it was observed inflammatory signs, and it was also obtained growth of pathogenics germs in 16 patients and in 17 (25.3 percent) it was confirmed the diagnosis of neoplasic disease by biopsy and/or bronchial brushing.

Evaluation of different types of chest symptoms for diagnosing pulmonary tuberculosis cases in community surveys.

BACKGROUND: Prevalence of tuberculosis (TB) is an important epidemiological index to measure the load of the disease in a community. A series of disease surveys were undertaken in rural community in Tiruvallur district in Tamilnadu, south India OBJECTIVE: To investigate the yield of pulmonary tuberculosis (TB) cases by different symptoms status and suggest predominant symptoms for detection of cases in the community based surveys. METHODS: Three disease surveys were conducted during 1999-2006, in a random sample of 82,000 adults aged > or = 15 years to estimate the prevalence and incidence of pulmonary TB. All subjects were screened for chest symptoms and chest radiography. Sputum examination was done among those who were either symptomatic or abnormal on X-ray or both. Cases observed through symptom inquiry were included for analysis. RESULTS: In survey-I, 65.6% had cough of > or = 14 days and yielded 79.1% of the total cases. In surveys II and III, symptomatic subjects with cough contributed 69.5% and 69.2% of the cases respectively. In survey I, 26.8% had symptoms without cough but with at least chest pain > or = 1 month contributed 8.4% of total cases. The corresponding proportions in subsequent surveys were 29.3, 11.5%; and 23.4, 11.2% respectively. The number of symptomatics without cough and chest pain but with fever > or = 1 month was negligible. CONCLUSION: The relative importance of cough as a predominant symptom was reiterated. The yield of pulmonary TB cases from symptomatics having fever of > or = 1 month was negligible. Fever may be excluded from the definition of symptomatics for screening the population in community surveys.

Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand).

SETTING: Patients of pulmonary tuberculosis (TB) attending the out and in patient department of pulmonary medicine, Himalayan Institute of Medical Sciences (HIMS), a post graduate institute and a large tertiary care center in Dehradun. OBJECTIVE: To compare the clinico-radiological pattern of pulmonary tuberculosis in the young adult (18-59 years) and elderly (> or = 60 years) patients. DESIGN: Prospective observational study of pulmonary and associated extra pulmonary tuberculosis cases, diagnosed between October 2005 to September 2006 in pulmonary medicine department of HIMS. RESULT: Mean age of young adult and elderly patients was 35.71 +/- 5.7 years and 68.57 +/- 3.03 years respectively. Elderly patients had a higher number of co-morbidities like diabetes mellitus, hypertension, and malignancy. Tuberculin positivity was less among elderly patients (36.0%) as compared to young adults (65.9%). Hemoptysis (29.5% vs. 6%), fever (95.4% vs. 76%) and night sweats (54.5% vs. 18.0%) were significantly higher in the young adult patients than the elderly. As for roentgenographic abnormalities, a higher involvement of lower zone (24.0% vs. 7.9%) and far advanced lesions (32.0% vs. 14.7%) were seen in the elderly patients as compared to young adults. The elderly showed a higher frequency of TB related mortality (8% vs. 1.1%) and associated extra pulmonary involvement (40% vs. 7%). CONCLUSION: Young adults are more likely to have hemoptysis, night sweats and positive PPD response while lower lung field involvement is more common in elderly.

Aspectos clínicos da tuberculose pulmonar em idosos atendidos em hospital universitário do Rio de Janeiro, RJ, Brasil / Clinical aspects of pulmonary tuberculosis in elderly patients from a university hospital in Rio de Janeiro, Brazil

OBJETIVOS: Avaliar as características clínicas e diagnósticas da tuberculose pulmonar (TP) em idosos. MÉTODOS: Foram comparados 117 pacientes com 60 anos de idade ou mais (idosos) e 464 pacientes entre 15 e 49 anos (não idosos), acompanhados no Instituto de Doenças do Tórax da Universidade Federal do Rio de Janeiro, de 1980 a 1996. RESULTADOS: Nos idosos, predominou história prévia de TP (OR = 2,09; IC95 por cento = 1,26-3,45; p = 0,002) enquanto o contato intradomiciliar de TP predominou nos não idosos (OR = 0,26; IC95 por cento = 0,10-0,66; p = 0,002). O tempo mediano para diagnóstico alcançou 90 dias nos idosos e 60 dias nos não idosos. No grupo idoso, prevaleceu a dispnéia (OR = 1,64; IC95 por cento = 1,06-2,53; p = 0,018) e o emagrecimento (OR = 1,66; IC95 por cento = 1,01-2,82; p = 0,047). Nos não idosos, prevaleceu a hemoptise (OR = 0,51; IC95 por cento = 0,32-0,81; p = 0,002), a dor torácica (OR = 0,62; IC95 por cento = 0,40-0,97; p = 0,027) e a febre (OR = 0,55; IC95 por cento = 0,35-0,86; p = 0,006). No padrão radiológico, predominaram as infiltrações e as cavitações; porém, o acometimento bilateral foi mais freqüente nos idosos (OR = 1,76; IC95 por cento = 1,12-2,78; p = 0.009). Não houve diferenças nas positividades do teste tuberculínico, baciloscopia e cultura de Mycobacterium tuberculosis. CONCLUSÕES: Há poucas diferenças clínicas e laboratoriais entre os grupos etários e o maior tempo de diagnóstico nos idosos deve-se à menor suspeição médica nestes pacientes.

OBJECTIVE: To evaluate clinical aspects and the diagnosis of pulmonary tuberculosis (PT) in the aged. METHODS: We compared 117 patients over 60 years of age (elderly group) and 464 patients aged 15 to 49 years old (nonelderly group) treated at the Thoracic Diseases Institute of the Federal University of Rio de Janeiro, from 1980 to 1996. RESULTS: Previous history of PT was predominant in the elderly group (OR = 2.09; 95 percent CI = 1.26-3.45; p = 0.002), whereas household contact with PT was predominant in the nonelderly group (OR = 0.26; 95 percent CI = 0.10-0.66; p = 0.002). Mean time for diagnosis was 90 days in the elderly group and 60 days in the nonelderly group. In the elderly group, dyspnea (OR = 1.64; 95 percent CI = 1.06-2.53; p = 0.018) and weight loss (OR = 1.66; 95 percent CI = 1.01-2.82; p = 0.047) were predominant. In the nonelderly group, hemoptysis (OR = 0.51; 95 percent CI = 0.32-0.81; p = 0.002), chest pain (OR = 0.62; 95 percent CI = 0.40-0.97; p = 0.027) and fever (OR = 0.55; 95 percent CI = 0.35-0.86; p = 0.006) were more common. The most common radiological abnormalities were infiltrates and cavitations. Bilateral involvement was more common in the elderly patients (OR = 1.76; 95 percent CI = 1.12-2.78; p = 0.009). There were no differences between the two groups regarding positivity for Mycobacterium tuberculosis identified through tuberculin skin testing, sputum smear microscopy and culture. CONCLUSIONS: There are few clinical and laboratory differences between the age groups. The delayed diagnosis in the elderly group can be explained by the low clinical suspicion in these patients.

Causas de hemoptisis en el Hospital Universitario de Neiva / Causes of hemoptysis in Neiva University Hospital

Se realizó un estudio de tipo serie de casos para presentar la experiencia acumulada del Hospital Universitario Hernando Moncaleano Perdomo (HUHMP) de la ciudad de Neiva durante enero de 1999 a julio del 2005, en pacientes con diagnóstico clínico de hemoptisis que fueron llevados a estudio fibrobroncoscópico. Objetivos: 1) Conocer cuáles son las principales causas de hemoptisis en pacientes que ingresan al HUHMP. 2) Aumentar los conocimientos de la epidemiología de la región. 3) Mejorar los protocolos de estudio y manejo en nuestra institución. Diseño: Serie de casos. Materiales y métodos: De 953 registros de fibrobroncoscopia se seleccionaron 42 casos de los que se logró recopilar la información completa para posteriormente realizar el análisis estadístico. Resultados: La causa más frecuente de hemoptisis fue la Tuberculosis (n = 15) en un 35.7/100, con evidencia endoscópica de sangrado en el 46/100. La frecuencia del cáncer broncogénico fue del 11.9/100. La fibrobroncoscopia y los estudios realizados con este procedimiento determinaron la causa del sangrado en el 78.5/100 de los casos. Conclusiones: Este estudio demuestra que la principal causa de hemoptisis en esta región es la tuberculosis. La fibrobroncoscopia es un examen inicial útil para establecer el diagnóstico en estos pacientes.

[Etiologic profile of hemoptysis in pneumology unit: [291 cases]]

To determine the profile of hemoptysis their main etiologies, we reviewed 291 cases hospitalized in 5 years [from 1980 to 1984] in a service of pneumology. Patients with hemoptysis represente 8,8% of all hospitalized patients. They have a mean age of 46 years and 47% of them have less than 50 years; 69,4% are men. The hemoptysis is a telltale sign of a thoracic pathology in 35,4%. It is trivial in 71,1% medium in 26,8%, important in 2,1%. In all the cases the chest radiograph is abnormal, the abnormalities evokating the etiologies in 70,8%. The prevailing etiologies are lung cancer [34,4%] and both active and sequelary tuberculosis [18,9%]. Among other causes bronchectasies hold an important place [15,1%] as well as broken hydatic cysts [9,3%]. The other causes are as follows: bacterial pneumopathies with or without abcess [7,2%], pulmonary aspergillosis [6,9%], chronic bronchitis with or without emphysema [3,5%]. Exceptional causes gather only 4 cases. In 3,1% no cause for the hemoptysis is demonstrated. This study emphasizes the leading role of lung cancer as an etiology of hemoptysis, even in country with a great tuberculosis prevalence. Nevertheless this outward reality is also due in part to the fact that most of patients with tuberculosis are hospitalized in specific yards