ABSTRACT
We report a 68-year-old woman presenting with pain and swelling in her left elbow. An elbow magnetic resonance with gadolinium evidenced bone marrow infiltration and a bone infarct. Given these findings, a body CT scan was performed which showed multiple mesenteric adenopathies and a large retroperitoneal mass. A lymph node biopsy confirmed a B cell lymphoma. Monoarthritis with no systemic manifestations represents a highly uncommon form of presentation of lymphoma. Moreover it usually affects inferior limbs, particularly in the presence of bone infarction.
Subject(s)
Humans , Female , Aged , Arthritis/etiology , Lymphoma, B-Cell/complications , Elbow/diagnostic imaging , Humerus/blood supply , Infarction/etiology , Arthritis/diagnosis , Bone Marrow Diseases/etiology , Bone Marrow Diseases/diagnostic imaging , Magnetic Resonance Imaging , Lymphoma, B-Cell/diagnostic imaging , Tomography, Spiral Computed , Infarction/diagnostic imagingABSTRACT
Primary orbital lymphoma is an extremely rare entity; most of the reported cases being MALT lymphoma. Herein we report a case of extranodal primary diffuse large B cell lymphoma in a 17 years old boy who presented with proptosis. The patient responded well to chemotherapy; presently he is in remission with no residual disease.
Subject(s)
Adolescent , Bone Neoplasms/diagnostic imaging , Humans , Lymphoma, B-Cell/diagnostic imaging , Lymphoma, Large B-Cell, Diffuse/diagnostic imaging , Male , Orbit/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of unknown origin. An abdominal CT scan revealed splenomegaly with focal splenic infarction. Splenectomy and a liver wedge biopsy showed sinusoidal-pattern infiltration of medium to large tumor cells with positive reaction to a B-lymphocyte marker. Findings on bone marrow examination showed proliferation of histiocytes with avid hemophagocytosis.