ABSTRACT
The aim of this study was to analyze the effects of an association of cryotherapy and therapeutic ultrasound on the treatment of muscle injured by impact. Fifty-five Wistar rats were divided into five groups (n = 11), Acute Injury (AI), Injury (I), Cryotherapy (CR), Therapeutic Ultrasound (TU) and Association of Cryotherapy and Therapeutic Ultrasound (CRTU). The CR and CRTU groups received applications of Cryotherapy three times (immediately, 24 and 48 h after injury) of 20 minutes duration. The TU and CRTU groups received applications of Therapeutic Ultrasound for seven days, for five minutes, in pulsed mode, 0.5 w/cm intensity, frequency 1 MHz. Body mass and gastrocnemius mass were analyzed. In addition to histological slides stained with hematoxylin and eosin used for morphometric analysis, picrosirius dye was used for quantification of collagen by Fractal Dimension (FD). The results of the intra-group analysis showed lower body mass and gastrocnemius in the CRTU group in relation to the AI (p = 0.001), I (p = 0.001), CR (p = 0.001) and TU groups (p = 0.001), and lower values of FD to quantify collagen in the CRTU group in relation to the AI (p = 0.007) and CR groups (p = 0.014). In summary, the present study showed that the association of Cryotherapy with Therapeutic Ultrasound promoted better results in the aspects analyzed compared to application of the therapies in isolation.
El objetivo del estudio fue evaluar los efectos de la asociación de las técnicas de crioterapia y ultrasonido terapéutico en el tratamiento de la lesión muscular por impacto. Fueron utilizadas 55 ratas Wistar, expuestas a lesión y separadas en grupos (n = 11): Lesión aguda (LA), Lesión (L), Crioterapia (CR), Ultrasonido Terapéutico (UT) y Crioterapia + Ultrasonido Terapéutico (CRUT). Los grupos CR y CRUT recibieron la aplicación, durante 20 minutos, en tres momentos (inmediatamente, 24 y 48 horas, después de la lesión). Los grupos UT y CRUT, recibieron UT por siete días, con una duración de cinco minutos, en modo pulsado, con una intensidad de 0,5 W/cm2 y frecuencia de 1 MHz. Fueran medidos el peso corporal y el peso de los músculos gastrocnemios y se realizaron cortes histológicos del músculo gastrocnemio, los cuales fueron teñidos con hematoxilina-eosina (HE) para el análisis morfométrico y con picrosirius para el análisis del colágeno por dimensión fractal (DF). Los resultados de los análisis intragrupo demostraron una menor disminución de la masa coporal y muscular en el grupo CRUT. Además, fue observado un valor inferior en la morfometría en el grupo CRUT en comparación a los grupos LA (p = 0,001), L (p = 0,001), CR (p = 0,001) y UT (p = 0,001), y un menor valor de la DF con respecto al colágeno en el grupo CRUT en comparación a los grupos LA (p = 0,007) y CR (p = 0,014). En síntesis, el presente estudio demostró que el protocolo de asociación de las técnicas de CR y UT causaron mayores respuestas benéficas en los aspectos analizados en comparación a los protocolos con los tratamientos aplicados de forma aislada.
Subject(s)
Animals , Male , Rats , Cryotherapy/methods , Muscle, Skeletal/injuries , Musculoskeletal Diseases/physiopathology , Musculoskeletal Diseases/therapy , Ultrasonic Therapy/methods , Fractals , Musculoskeletal Diseases/pathology , Rats, Wistar , RegenerationABSTRACT
Sarcoidosis is a multisystem granulomatous disease of unknown cause. The osteoarticular involvement in sarcoidosis is rare and is often associated with cutaneous and long-standing chronic multisystem disease. More common in black women, osseous sarcoidosis is difficult to diagnose, with an incidence of 3 to 13%. The most characteristic radiological clinical picture evidences rounded, well-defined cysts, with no periosteal reaction and without peripheral sclerosis. The small bones of hands and feet are the most frequently involved sites. This report aims to demonstrate a rare case of osteoarticular sarcoidosis with characteristic clinical presentation, and highlight the importance of detecting osteoarticular involvement in this pathology.
Subject(s)
Aged, 80 and over , Female , Humans , Granulomatous Disease, Chronic/pathology , Musculoskeletal Diseases/pathology , Sarcoidosis/pathology , Skin Diseases/pathology , Granulomatous Disease, Chronic , Hand Bones/pathology , Hand Bones , Musculoskeletal Diseases , Sarcoidosis , Skin Diseases , Telangiectasis/pathologyABSTRACT
El Rabdomiosarcoma es el sarcoma de tejidos blandos de origen musculoesqueléticos más frecuente en niños menores de 15 años y uno de los más comunes en adolescentes y adultos jóvenes. (1) Las áreas del cuerpo más comunes donde puede alojarse este tumor son la cabeza, el cuello, la vejiga, la vagina, los brazos, las piernas y el tronco. Aunque también puede encontrarse en la próstata, el oído medio y el sistema de conductos biliares. (2) En los niños con rabdomiosarcoma embrionario, esta anomalía se encuentra en el cromosoma 11, mientras el alveolar en los cromosomas 2 y 13. (1) Se reconocen tres subtipos: embrionario, alveolar y pleomórfico. El embrionario se observa en niños y adolescentes menores de 15 años y se localiza principalmente en la cabeza y en el cuello, tracto urogenital, retroperitoneo y extremidades. Los síntomas pueden incluir una masa visible o palpable que puede ser doloroso o no, parestesia, dolor. (2) El diagnóstico se establece a través del examen físico, historia médica completa, así como estudios imagenológicos, biopsia y punción de medula ósea. (3) El tratamiento específico será dado por la localización del tumor primario y el estadio del tumor, en algunos pacientes se administra quimioterapia preoperatorio en un intento de reducir la extensión de la intervención y de preservar órganos vitales. El pronóstico se relaciona con la edad del paciente, sitio de origen, resecabilidad. (4)
Subject(s)
Humans , Male , Child , /physiology , Musculoskeletal Diseases/pathology , Liver/injuries , Head and Neck Neoplasms/surgery , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/drug therapy , Drug Therapy/methods , Radiography, Abdominal/methods , Respiratory Sounds/physiology , Appendectomy/methods , Biopsy/methods , Embryology , Pediatrics , Rhabdomyosarcoma, Embryonal/diagnosis , Rhabdomyosarcoma, Embryonal/pathology , Rhabdomyosarcoma, Embryonal/therapy , Sarcoma/pathologyABSTRACT
Marfan syndrome (MFS) is a potentially fatal connective disorder that is inherited as an autosomal dominant trait with a prevalence of around 2-3 in 10000 live births. It is characterized by defects in the cardiovascular, skeletal and ocular systems. Evidence from genetic indicates that mutations in FBN1, the gene that encodes fibrillin-1 are responsible for MFS. In addition to skeletal, ocular, and cardiovascular feathers, patients with MFS have also involvement of skin, integument, lungs, and muscle tissue, and the condition in sudden death is also very common due to severe abnormalities of cardiovascular system.
Subject(s)
Humans , Cardiovascular Diseases/pathology , Eye Diseases/pathology , Genotype , Marfan Syndrome/pathology , Microfilament Proteins/genetics , Musculoskeletal Diseases/pathology , Mutation , PhenotypeABSTRACT
The WHO-ILAR Community Oriented Program for Control of Rheumatic Diseases [COPCORD] primarily aims to estimate the burden of musculoskeletal symptoms/disorders. We estimated the incidence of musculoskeletal pain in the first community-based COPCORD study in Kuwait. The validated Arabic version of the WHOILAR COPCORD Core Questionnaire was used in a survey of 2500 randomly selected Kuwaiti households to assess the frequency of musculoskeletal pain, disability, and health-seeking behavior in adult Kuwaitis. Those subjects reporting no musculoskeletal pain were identified and followed-up for a period of one year by contacting them every 2 weeks. Once a respondent reported pain, an appointment to report to hospital was offered and the subject was examined by a rheumatologist using American College of Rheumatology [ACR] criteria. Of 5159 adults who were non-complainers in an earlier prevalence phase of the study, 3341 responded to phone calls [response rate of 65%]. The incidence of musculoskeletal pain was 6.6% [95%CI, 3.4%- 9.7%]. Age- and sex-adjusted incidence rates were 7.2% [95%CI, 3.4%- 10.5%] for females and 6.1% [95%CI, 3.1%-9.2%] for males. The incidence rate increased with increasing age, body mass index, and with being married. The common sites of pain were knee, low back and shoulder. The incidence of musculoskeletal pain among Kuwaiti adults is reported for the first time. Further studies adopting the same instrument in other communities are warranted to compare with our findings
Subject(s)
Humans , Male , Female , Musculoskeletal Diseases/pathology , Disability Evaluation , Pain/epidemiology , Patient Acceptance of Health Care , Public Health , Surveys and Questionnaires , World Health Organization , Cross-Cultural ComparisonABSTRACT
El Fibrosarcoma es un tumor maligno de partes blandas primario o secundario a lesiones benignas pre-existentes, pueden ser endostal o parostal, comprende aproximadamente el 6.2 por ciento de los tumores primarios del hueso, predomimante en hombres, entre la 3era y 6ta década de vida, tiene predilección por el fémur, húmero, tibia y pelvis. Se describe paciente masculino de 25 años de edad quien inicia enfermedad en noviembre 2002 con aumento de volumen progresivo y dolor en rodilla derecha, acompañandose de limitación funcional; consulta en mayo 2003 con clínica exacerbada iniciándose su estudio.
Subject(s)
Humans , Male , Adult , Pain/diagnosis , Fibrosarcoma/diagnosis , Fibrosarcoma/pathology , Knee Injuries/diagnosis , Arthritis, Infectious , Musculoskeletal Diseases/diagnosis , Musculoskeletal Diseases/pathologyABSTRACT
Varios estudos demonstram que as mulheres apresentam mais dor que os homens. Entretanto, os estudos sobre lombalgia e dor toracica nao sao conclusivos. Em casos de dores articulares e fibromialgia existe...