1.
Article
in English
| IMSEAR
| ID: sea-42894
Subject(s)
Adult , Animals , Bile Acids and Salts/analysis , Female , Humans , Lipids/analysis , Liver Diseases, Parasitic/metabolism , Male , Middle Aged , Opisthorchiasis/metabolism , Opisthorchis
2.
Southeast Asian J Trop Med Public Health
;
1983 Sep; 14(3): 290-3
Article
in English
| IMSEAR
| ID: sea-34491
ABSTRACT
The dose of praziquantel required to achieve a 100% worm reduction in O. viverrini infected hamsters was found to be 300 mg/kg body weight. The drug was administered orally for 1 day by dividing a total dose into 3 equal doses at 4 h interval. The effect of praziquantel treatment on liver collagen was followed by measuring liver collagen content in at various intervals after administration of the drug. A decrease in collagen content in the infected livers occurred within a few weeks following the treatment suggesting a recovery from liver fibrosis.