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1.
Chinese Journal of Epidemiology ; (12): 169-174, 2022.
Article in Chinese | WPRIM | ID: wpr-935366

ABSTRACT

Objective: To explore the association of spicy food consumption and risk of lip, oral cavity, and pharynx cancers (LOCPs) in Chinese adults. Methods: Based on the baseline survey and long-term follow-up of the China Kadoorie Biobank (CKB) study, Cox proportional hazard regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (95%CI) for associations between spicy food consumption and LOCPs incidence. Results: Of the 510 145 participants included at baseline, 30.1% reported daily spicy food consumption. During a mean follow-up of 10.8 (2.0) years, we documented 767 LOCPs cases. Multivariate adjusted analyses showed that the risk of LOCPs incidence decreased with the frequency of spicy food intake (trend P=0.003), with HR of 0.69 (95%CI:0.54-0.88) for daily spicy food consumers, compared with never or occasional consumers. Participants who preferred moderate pungency degrees had the lowest risk of LOCPs, with a 33%[0.67(95%CI:0.52-0.87)] reduced risk compared to those who consumed spicy food less than once per week. The later the starting age, the lower the risk (trend P=0.004). Those who started eating spicy food after 18 years old had the lowest risk of LOCPs incidence, with adjusted HR (95%CI) of 0.70(0.54-0.92). Conclusions: Spicy food intake might be associated with a decreased risk of LOCPs incidence. Such association was independent of healthy lifestyles. Advocating moderate-pungency spicy food consumption and healthy lifestyles might help prevent LOCPs.


Subject(s)
Adolescent , Adult , Humans , China/epidemiology , Lip , Pharyngeal Neoplasms/epidemiology , Prospective Studies , Risk Factors , Spices
2.
Rev. panam. salud pública ; 32(3): 185-191, Sept. 2012.
Article in Portuguese | LILACS | ID: lil-654609

ABSTRACT

Objetivo. Avaliar a relação entre alimentos de origem animal e câncer de boca e orofaringe.Métodos. Estudo caso-controle, de base hospitalar, pareado por sexo e idade (± 5 anos) coma coleta de dados realizada entre julho de 2006 e junho de 2008. A amostra foi composta por296 pacientes com câncer de boca e orofaringe e 296 pacientes sem histórico de câncer atendidosem quatro hospitais da cidade de São Paulo (SP), Brasil. Foi aplicado um questionário semiestruturado,para a coleta de dados relativos à condição socioeconômica e aos hábitos deletérios(tabaco e bebidas alcoólicas). Para avaliação do consumo alimentar, utilizou-se um questionáriode frequência alimentar qualitativo. A análise se deu por meio de modelos de regressão logísticamultivariada, que consideraram a hierarquia existente entre as características estudadas.Resultados. Entre os alimentos de origem animal, o consumo frequente de carne bovina(OR = 2,73; IC95% = 1,27–5,87; P < 0,001), bacon (OR = 2,48; IC95% = 1,30–4,74;P < 0,001) e ovos (OR = 3,04; IC95% = 1,51–6,15; P < 0,001) estava relacionado ao aumentono risco de câncer de boca e orofaringe, tanto na análise univariada quanto na multivariada.Entre os laticínios, o leite apresentou efeito protetor contra a doença (OR = 0,41; IC95% =0,21–0,82; P < 0,001).Conclusões. O presente estudo sustenta a hipótese de que alimentos de origem animalpodem estar relacionados à etiologia do câncer de boca e orofaringe. Essa informação podeorientar políticas preventivas contra a doença, gerando benefícios para a saúde pública.


Objective. Evaluate the relationship between animal-derived foods and mouth andoropharyngeal cancer.Methods. Hospital-based case-control study matched by sex and age (± 5 years) withdata collected between July of 2006 and June of 2008. The sample contained 296 patientswith mouth and oropharyngeal cancer and 296 patients without a cancer history who weretreated in four hospitals in the City of São Paulo, State of São Paulo, Brazil. A semistructuredquestionnaire was administered to collect data regarding socioeconomic condition andharmful habits (tobacco and alcoholic beverage consumption). To assess eating habits,a qualitative questionnaire that asked about the frequency of food consumption wasused. The analysis was rendered by means of multivariate logistic regression models thatconsidered the existing hierarchy among the characteristics studied.Results. Among foods of animal origin, frequent consumption of beef (OR = 2.73;CI95% = 1.27–5.87; P < 0.001), bacon (OR = 2.48; CI95% = 1.30–4.74; P < 0.001) andeggs (OR = 3.04; CI95% = 1.51–6.15; P < 0.001) was linked to an increased risk ofmouth and oropharyngeal cancer, in both the univariate and multivariate analyses.Among dairy products, milk showed a protective effect against the disease (OR =0.41; CI95% = 0.21–0.82; P < 0.001).Conclusions. This study affirms the hypothesis that animal-derived foods can beetiologically linked to mouth and oropharyngeal cancer. This information can guidepolicies to prevent these diseases, generating public health benefits.


Subject(s)
Humans , Animals , Male , Female , Adult , Middle Aged , Aged , Cattle , Diet/adverse effects , Eggs/adverse effects , Meat/adverse effects , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Alcohol Drinking/adverse effects , Alcohol Drinking/epidemiology , Brazil/epidemiology , Case-Control Studies , Causality , Dairy Products/adverse effects , Feeding Behavior , Fruit , Meat Products/adverse effects , Mouth Neoplasms/etiology , Pharyngeal Neoplasms/etiology , Risk Factors , Sheep , Smoking/adverse effects , Smoking/epidemiology , Socioeconomic Factors , Swine , Vegetables
3.
EMHJ-Eastern Mediterranean Health Journal. 2012; 18 (9): 985-991
in English | IMEMR | ID: emr-158992

ABSTRACT

Hospital-based studies have revealed very high relative frequencies of oral and pharyngeal cancers in Yemen. This study estimated the relative frequencies of oral and pharyngeal cancers among Yemeni cancer patients registered in 2007 and 2008 and determined patients' demographic and tumour characteristics. Of the registered 7515 cases, 302 [4.0%] were oral cancer and 239 [3.2%] pharyngeal cancer. Oral cancer was significantly more frequent among females while pharyngeal cancer was significantly more frequent among males. Oral cancer patients were significantly older than pharyngeal cancer patients. The tongue was the most affected oral site [53.6%] while the nasopharynx comprised 89.5% of pharyngeal cancers. The most frequent morphological type was squamous cell carcinoma [93.2%]. High proportions of oral cancer [71.5%] and pharyngeal cancer [77.4%] patients were diagnosed at advanced stages. Compared with other countries in the region, oral cancer and nasopharyngeal cancer represent substantial national health burdens in Yemen


Subject(s)
Humans , Male , Female , Pharyngeal Neoplasms/epidemiology , Retrospective Studies , Tongue , Nasopharynx , Carcinoma, Squamous Cell
4.
RGO (Porto Alegre) ; 58(3): 351-355, jul.-set. 2010. tab
Article in Portuguese | LILACS, BBO | ID: biblio-874137

ABSTRACT

Objetivo: Avaliar o perfil epidemiológico de uma coorte de pacientes diagnosticados com câncer de boca e faringe de um Centro de Alta Complexidade em Oncologia nível II do município de Juiz de Fora, Minas Gerais, entre janeiro 2005 e dezembro 2007. Métodos: Estudo transversal, fundamentado na análise retrospectiva e descritiva de 101 prontuários médicos. Resultados: Dos 101 pacientes, 84,2% eram homens com baixo nível de escolaridade, bem como trabalhadores braçais (35,8%) e 15,8%, mulheres, donas-de-casa (5,5%). A razão de sexo foi 5,3:1; idade média de 56,5 anos, sendo que 49,5% dos casos apresentavam ao diagnóstico, idade inferior à média do grupo. Com relação aos hábitos de risco, 67,1% eram tabagistas e o etilismo foi descrito em 49,3% dos prontuários, sendo que o relato de consumo diário, sob forma de bebidas destiladas (47,3%), foi feito por 60% dos casos. O sítio anatômico mais prevalente foi a língua (32%), orofaringe (18,5%), assoalho de boca (12,4%). No estadiamento ao diagnóstico verificou-se maior número de tumores T4 (39,4%), N2 (38,3%), M0 (91,4%). Conclusão: O diagnóstico das lesões bucais malignas foi tardio, observando-se estadiamento T4 em 39,4% dos casos. Assim, para que oportunidades diagnósticas não sejam comprometidas é necessário o treinamento dos profissionais de saúde para abordagem dos fatores preventivos e do diagnóstico precoce e, finalmente a elaboração de rotinas programadas nos serviços de saúde para detecção de lesões suspeitas à inabilidade de alguns médicos e dentistas no reconhecimento do câncer. Contudo, para que oportunidades diagnósticas não sejam perdidas é necessário o treinamento dos profissionais de saúde para abordagem dos fatores preventivos e do diagnóstico precoce e, finalmente a elaboração de rotinas programadas nos serviços de saúde para detecção de lesões suspeitas.


Objective: The aim of this study was to evaluate the epidemiological profile of a cohort of patients diagnosed with oral or pharyngeal cancer in a High Complexity Oncology Center (level II) in Juiz de Fora, Minas Gerais, Brazil, from January 2005 to December 2007. Methods: This cross-sectional study was based on the retrospective and descriptive analysis of 101 medical records. Results: Of the 101 patients 84.2% were males with low education levels, of which 35.8% were blue-collar workers and 15.8% were females, of which 5.5% were homemakers. The gender ratio was 5.3:1 and the mean age of the sample was 56.5 years. The age of 49.5% of the individuals at diagnosis was below the mean age of the group. Regarding risk factors, 67.1% were smokers and 49.3% were alcoholics; 60% of the sample reported drinking distilled beverages (47.3%) daily. The most common sites were the tongue (32%), oropharynx (18.5%) and floor of mouth (12.4%). Staging at diagnosis revealed that 39.4% were T4, 38.3% were N2 and 91.4% were M0. Conclusion: The diagnosis of malignant oral lesions was late: 39.4% of the sample was in stage T4. Thus, for diagnostic opportunities not to be missed, it is necessary to train health professionals so that they can address the factors of prevention and early diagnosis. It is also necessary to develop routines in health services to detect suspicious lesions since some physicians and dentists are unable to recognize cancerous lesions.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Cross-Sectional Studies , Age Factors , Sex Factors , Socioeconomic Factors , Risk Factors
5.
Iranian Journal of Public Health. 2009; 38 (2): 90-97
in English | IMEMR | ID: emr-100253

ABSTRACT

Epidemiologic aspects of oral and pharyngeal cancers in Iran have not been studied adequately. We evaluated age-adjusted incidence rates by sex using pathological confirmed cases between 1991 and 2002 in Kerman Province, south eastern Iran. The information of cases was collected actively from all of the 18 histopathology departments around the province. The standardize risks were estimated using standard world population and the risk ratio for age and sex were estimated using negative binomial model. The total number of newly diagnosed malignant oral and pharyngeal cancers was 334, represented 3.1% of all newly diagnosed cancers. The age-adjusted incidence rate for oropharyngeal cancers was 2.21 cases per 100 000 populations per year. The results suggested that those age 40 and over were 18.1 times more likely to develop oral and pharyngeal cancer than the younger group. The risk of developing oral and pharyngeal cancers was 1.75 times more common in males than females. This study showed that the overall incidence of oral and pharyngeal cancers in Kerman Province was lower than that in most parts of the world. The lower incidence might be due to behavioral differences such as low consumption of alcohol, chewing tobacco, and spicy foods


Subject(s)
Humans , Male , Female , Pharyngeal Neoplasms/epidemiology , Lip Neoplasms , Tongue Neoplasms
6.
Rev. AMRIGS ; 52(3): 158-163, jul.-set. 2008. graf, tab
Article in Portuguese | LILACS | ID: biblio-849329

ABSTRACT

Introdução: O câncer é um sério problema de saúde pública e estima-se para o ano 2008 que o câncer bucal ocupará a sétima posição dentre os novos casos no Brasil. Objetivo: Descrever e analisar o quadro de morbidade por cânceres bucal e faríngeo na cidade de Recife PE, nos anos de 1995 a 2001. Metodologia: Tratou- se de um estudo longitudinal, onde casos novos de câncer registrados no Sistema de Registros de Câncer de Base Populacional ­ SisBasePop foram os residentes em Recife com diagnóstico confirmado, incluindo-se tumores de localização primária maligno e in situ, codificados segundo a CIDO2. As taxas de incidência foram padronizadas por sexo e idade segundo a população mundial proposta por Segi (1960) e modificada por Doll et al. (1966). As análises foram realizadas no Programa Microsoft Office Excel 2003. Resultados: Os cânceres bucal e faríngeo registrados foram responsáveis por 3,8% (n=671) de todos os casos novos de cânceres (n=17.470), sendo a 4a localização anatômica mais comum nos homens (n=441) e a 11a nas mulheres (n=225); dos casos de cânceres bucal e faríngeo registrados 66,3% ocorreram em homens. Nas mulheres chama à atenção um percentual elevado em crianças e adolescentes (12%). Conclusões: As taxas de incidência dos cânceres bucal e faríngeo foram maiores no sexo masculino, aumentaram com a idade do paciente e a topografia mais acometida pela doença na cavidade bucal foi a língua (AU)


Introduction: Cancer is a serious public health problem, and it is estimated that oral cancer will be in the seventh position among new cases in Brazil for the year 2008. Objective: To describe and to analyze oral and oropharyngeal cancers morbidity in the city of Recife (PE) in the 1995-2001 period. Methodology: This is a longitudinal study, where new cases of cancer included in the System of Population-based Registers of Cancer (SisBasePop) were the city residents with a confirmed diagnosis, including malignant tumors in primary localization and in situ, coded according to CIDO2. The incidence rates were standardized by sex and age against worldwide population as proposed by Segi (1960) and modified by Doll et al. (1966). Data analysis was performed through Microsoft Office Excel 2003. Results: Oral and oropharyngeal cancers accounted for 3.8% (n=671) of all the new registered cases of cancer (n=17.470), being the 4th most common anatomical localization in males (n=441) and the 11th in females (n=225); 66.3% of these cases occurred in males. Among females, the high percentage of cases in children and adolescents is noteworthy (12%). Conclusions: In this series, the incidence rates of oral and pharyngeal cancers were higher for males and increased with patient age, and the site most often affected by the disease in the oral cavity was the tongue (AU)


Subject(s)
Humans , Male , Female , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Brazil/epidemiology , Retrospective Studies , Cohort Studies
7.
Cad. saúde pública ; 23(3): 553-564, mar. 2007. tab
Article in Portuguese | LILACS | ID: lil-441984

ABSTRACT

Neste estudo, investigou-se os fatores dietéticos associados com o câncer oral, em um estudo tipo caso-controle de base hospitalar no Município de São Paulo, Brasil, entre 1998 e 2002. Participaram 835 indivíduos, sendo 366 casos incidentes de câncer de cavidade oral ou faringe e 469 controles. Os dados de consumo alimentar foram obtidos por um Questionário de Freqüência Alimentar (QFA). Os valores de odds ratio (OR) e intervalos com 95 por cento de confiança (IC95 por cento) foram estimados por regressão logística não condicional, ajustada por potenciais fatores de confusão. Verificaram-se associações inversas entre o câncer oral e o consumo mais elevado de feijão, OR = 0,37 (IC95 por cento: 0,22-0,64), vegetais crus, OR = 0,51 (IC95 por cento: 0,29-0,93) e para o tercil intermediário de arroz e massas, OR = 0,56 (IC95 por cento: 0,38-0,83). Associações diretas foram observadas para o mais elevado consumo de ovos, OR = 1,84 (IC95 por cento: 1,23-2,75), batata, OR = 2,22 (IC95 por cento: 1,53-3,25) e leite, OR= 1,80 (IC95 por cento: 1,09-2,98). Alimentos básicos da dieta do brasileiro, como arroz e feijão, emergiram como fatores de proteção para o câncer oral, independente de outros fatores de risco.


Dietary factors associated with oral cancer were investigated in a case-control hospital-based study in the city of São Paulo, Brazil, from 1998 to 2002. A total of 835 subjects, 366 with histologically confirmed incident cases of oral-cavity or pharyngeal cancer and 469 controls participated in the study. Dietary data were collected with a food frequency questionnaire (FFQ). Odds ratios (OR) and 95 percent confidence intervals (95 percentCI) were obtained from unconditional logistic regression, adjusted for potential confounders. Inverse associations with risk of oral cancer were found for the highest intake of beans, OR = 0.37 (95 percentCI: 0.22-0.64), raw vegetables, OR = 0.51 (95 percentCI: 0.29-0.93) and the intermediate tertile of rice and pasta intake, OR = 0.56 (95 percentCI: 0.38-0.83). Positive associations were observed for the highest intake of eggs, OR = 1.84 (95 percentCI: 1.23-2.75), potatoes, OR = 2.22 (95 percentCI: 1.53-3.25), and milk, OR= 1.80 (95 percentCI: 1.09-2.98). Some traditional Brazilian foods like rice and beans emerged as protective factors against oral cancer, independently of other risk factors.


Subject(s)
Humans , Male , Female , Case-Control Studies , Feeding Behavior , Nutrition Surveys , Mouth Neoplasms/epidemiology , Mouth Neoplasms/mortality , Pharyngeal Neoplasms/epidemiology , Pharyngeal Neoplasms/mortality , Incidence , Surveys and Questionnaires , Risk Factors , Data Interpretation, Statistical
8.
São Paulo; s.n; 2006. 62 + anexos p. mapas, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-444662

ABSTRACT

O câncer das vias aéreas e digestivas superiores compreendem um grupo de tumores que se distribuem por diversas regiões anatômicas. Para a maioria das localizações os principais fatores de risco são o tabaco e o álcool. Como os fatores de risco são conhecidos espera-se que as diversas campanhas de prevenção e detecção precoce estivessem propiciando à diminuição da incidência. Objetivos: Estimar em algumas localidades do mundo as tendências da incidência dos tumores de lábio, língua, boca, glândulas salivares, orofaringe, nasofaringe e hipofaringe de 1969 a 1999. Métodos: Analisou-se os coeficientes de incidência de 18 registros de câncer de base populacional que possuíam toda a série histórica publicada no "Cancer Incidence in Five Continents". Utilizando-se modelos de regressão polinomial. Resultados: Houve tendência de aumento, estatisticamente significativo, para o câncer de língua e boca em São Paulo em mulheres e em homens de diversos países europeus e localidades dos EUA. Em contrapartida houve queda em Porto Rico, Mumbai e Cingapura. O câncer de lábio decresceu na maioria das localidades em homens. Entretanto em países do norte da Europa e em Iowa houve aumento em mulheres. O câncer de orofaringe aumentou em homens na Europa e em Iowa e decresceu em Cali, Quebec, e localidades da Ásia.O câncer da hipofaringe apresentou tendência crescente em várias localidades da Europa em homens e queda na Suécia, Inglaterra, Cingapura e Porto Rico. Conclusão os tumores de língua, boca e orofaringe continuam apresentando tendências de crescimento para diversas localidades. Por isso há a necessidade de campanhas propiciando a prevenção e a detecção precoce.


Subject(s)
Male , Female , Humans , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Salivary Gland Neoplasms/epidemiology , Incidence
9.
Rev. méd. Chile ; 133(5): 555-563, mayo 2005. tab, graf
Article in Spanish | LILACS, MINSALCHILE | ID: lil-429057

ABSTRACT

Background: Most oral cancers are squamous cell carcinomas (90%) which are two to four times more common in men than in women. The reasons for these differences are associated with exposure to factors such as tobacco and alcohol. Age is also considered as a risk factor (about 90% of the cases are diagnosed after 45 years of age). Aim: To analyze the frequency of oral cavity cancer during the last years in Chile. Material and methods: Mortality rates were obtained from death records of the "Instituto Nacional de Estadísticas" and publications of the World Health Organization, from 1955 to 2002. Morbidity from 1969 to 2002 was obtained from hospital discharge records of the Chilean Ministry of Health. Results: Oral cancer corresponded to 1.6% of total cancer cases in Chile, with a male:female ratio of 2.3 to 1. Deaths due to oral cancer was 1% of all cancer deaths, with a male:female ratio of 2.8 to 1. The morbidity rate for both genders increased while the mortality rate was relatively constant. However, we observed an increase in the mortality rate among women from 1980 to 2002, associated with more than 100% increase in the frecuency of smoking, between 1970 and 1998. The most common anatomical location was the tongue. Conclusions: The incidences of oral cancer is increasing in Chilean women, but men are more commonly affected.


Subject(s)
Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Chile/epidemiology , Death Certificates , Incidence , Morbidity , Mouth Neoplasms/mortality , Neoplasms, Squamous Cell/epidemiology , Neoplasms, Squamous Cell/mortality , Pharyngeal Neoplasms/mortality , Risk Factors , Sex Distribution
10.
Article in English | IMSEAR | ID: sea-37743

ABSTRACT

The objective of the study was to provide an overview of the demographics of cancer of the oral cavity and pharynx in Karachi South (1995-2001), and identify potential risk factors. Cases recorded for Karachi South, at Karachi Cancer Registry during 1(st) January 1995 to 31(st) December 2002 were analysed. For maximum completion of data cancer cases, recorded from 1(st) January 1995 to 31(st) December 2001 were included for final analysis. The age standardized incidence rates per 100000 population (ASIRs) for cancer of the oral cavity (excluding salivary gland) in Karachi South were 17.1 and 16.5 in males and females whereas the ASIRs for cancer of the pharynx (excluding nasopharynx) were 7.1 and 2.4 in males and females, respectively. The oral pharyngeal ratios were 2.4 and 6.9 for males and females and gender ratios (M F) were 1.04 for the oral cavity and 3.0 for the pharynx. The mean ages were 51 years (95% CI 49.6; 52.2) and 56.1 years (95% CI 54.4; 57.8) respectively. Cancer of the oral cavity ranked 2(nd) in Karachi in both genders. Cancer of the pharynx ranked 7(th) in males and 14(th) in females. Approximately 97% of the oral cavity and pharyngeal cancers were histologically confirmed. The majority of the oral (47.1%) and pharyngeal (51.9%) cancer cases presented as grade II lesions, and were discovered at advanced stages. Of the cancers reported during 1995-2001, 60.4% of the oral and 78.1% of the pharyngeal lesions had spread to a distant site at the time of diagnosis. Squamous cell carcinoma comprised 96.5% and 91.8% of the totals. The incidences of these cancers are comparable to the highest risk regions of the world. As distinct from other geographical areas oral cancer is as common in females as in males, which may reflect the pattern of exposure to known risk factors such as betal quid, arecanut and tobacco and the absence of alcohol as a risk factor in both genders. Apergillus contamination of arecanut could also be a risk factor but no confirmation studies or quantification is available. Despite the common risk factors, incidence of pharyngeal cancer is three times higher in men as compared with women. The keys to reducing the incidence and mortality due to oral and pharyngeal cancers are prevention and control, emphasizing cessation of tobacco use and cancer screening. However a targeted cancer and tobacco control program does not presently exist in Pakistan.


Subject(s)
Carcinoma, Squamous Cell/epidemiology , Female , Humans , Incidence , Male , Middle Aged , Mouth Neoplasms/epidemiology , Pakistan/epidemiology , Pharyngeal Neoplasms/epidemiology , Risk Factors
11.
Rev. bras. cancerol ; 46(1): 79-86, mar. 2000. tab
Article in Portuguese | LILACS | ID: lil-279248

ABSTRACT

Trata-se de um estudo epidemiológico, de tendência temporal, sobre a mortalidade por câncer de boca e faringe na população residente de Natal, durante o período de 1981 a 1995. Os dados foram coletados a partir da declaração de óbito (D.O) dos residentes em Natal, de 1981 a 1995, através do Sistema de Informação de Mortalidade do Rio Grande do Norte, disponível em CD-ROM e dos dados da população de Natal, gerados a partir dos Censos Demográficos de 1980 e de 1991. Para a análise, os dados foram agrupados em triênios consecutivos, tomando-se como variáveis principais o sexo, a faixa etária e as localizações anatômicas. Os resultados mostraram que de 1981-83 para 1993-95, o risco de morrer em Natal declinou de 756,93 para 630,96 por 100.000 homens e de 528,01 para 417,00 por 100.000 mulheres; entretanto, quando avaliaadas taxas para o câncer de boca e faringe, estas assumiram um perfil ascendente, passando de 2,60 para 6,66 em homens e de 1,55 para 2,08, em mulheres...


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Mouth Neoplasms/epidemiology , Mouth Neoplasms/mortality , Pharyngeal Neoplasms/epidemiology , Pharyngeal Neoplasms/mortality , Aged, 80 and over , Brazil/epidemiology
12.
Rev. bras. cancerol ; 44(4): 317-25, out.-dez. 1998.
Article in Portuguese | LILACS | ID: lil-258257

ABSTRACT

O presente artigo realizou breve análise de perfil epidemiológico de tumores de boca e faringe no Brasil e no mundo, bem como uma revisão da literatura pertinente a seus fatores de risco. Sua incidência, geralmente, varia entre 2 porcento a 30 porcento do total dos novos casos de câncer no mundo, e é fortemente influenciada pela localização geográfica. No Brasil, é a sexta localização anatômica mais comum nos Registros de Base Populacional entre os homens, sendo que a localização envolvendo a língua corresponde a 40 porcento do total de casos. Os principais fatores de risco são o tabaco, o álcool e a interação entre ambos, que exibem forte efeito multiplicativo sobre o risco. A quantidade consumida e o tempo de exposição a estes dois fatorers exibem, comumente, gradiente crescente de risco para o câncer. Elementos da dieta são considerados fatores de proteção, especialmente o B-caroteno, enquanto estados de carência nutricional são comumente percebidos entre os casos. Condições de precária saúde bucal são achados comuns entre os casos de câncer de boca e faringe. As recentes linhas de pesquisa em patogênese e prevenção do câncer de boca e faringe têm estudado a contribuição viral e genética. o comprometimento de grupos etários mais jovens e de mulheres provavelmente deve-se à universalização dos fatores de risco, levando a esta modificação do perfil epidemiológico.


Subject(s)
Humans , Male , Female , Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Alcoholism/complications , Brazil/epidemiology , Incidence , Risk Factors , Smoking/adverse effects
13.
Rev. med. (Säo Paulo) ; 77(3): 143-8, maio-jul. 1998. ilus, tab
Article in Portuguese | LILACS | ID: lil-236679

ABSTRACT

As afeccoes malignas das tres regioes da faringe - nasofaringe, orofaringe e hipofaringe - sao bastante distintas entre si no que diz respeito ao quadro clinico e ao tratamento. Enquanto na nasofaringe os tumores sao menos diferenciados e tratados principalmente pela radioterapia, os tumores da orofaringe e da hipofaringe sao mais diferenciados e, como regra, respondem melhor a terapeutica cirurgica associada a radioterapia pos-operatoria. Na terapeutica dos tumores da faringe, os linfonodos cervicais devem ser tratados pelo esvaziamento cervical e / ou pela radioterapia


Subject(s)
Humans , Clinical Diagnosis , Diagnostic Imaging , Pharyngeal Neoplasms/surgery , Carcinoma , Risk Factors , Neoplasm Staging , Pharyngeal Neoplasms/diagnosis , Pharyngeal Neoplasms/epidemiology , Pharyngeal Neoplasms/drug therapy , Pharyngeal Neoplasms/radiotherapy , Pharyngeal Neoplasms/therapy
14.
Rio de Janeiro; s.n; 1997. 139 p. tab, graf.
Thesis in Portuguese | LILACS | ID: lil-189553

ABSTRACT

Realiza uma extensa revisäo da literatura pertinente a fatores de risco para tumores de boca e faringe, bem como uma análise da incidência e mortalidade por estas neoplasias no Brasil, com base nos registros de câncer de base populacional. Elabora um estudo utilizando uma coorte hospitalar que reuniu 704 casos de câncer de boca e faringe (CID-O140-149) registrados no Hospital do Câncer do Instituto Nacional do Câncer/RJ, no período de 1986-87. Obteve a descriçäo do perfil dos acometidos e a análise de sobrevida deste grupo com base em variáveis de importância prognóstica. Para isto, foi desenhada uma ficha para coleta de dados, cujas variáveis foram retiradas do prontuário médico destes pacientes. O estudo de sobrevida permite verificar uma sobrevida considerada moderada, superestimada por localizaçöes de bom prognóstico como lábio e glândula salivar. Entretanto, salienta que tumores de língua e faringe, alguns dos mais frequentes, apresentam prognóstico bastante desfavorável. Variáveis relativas ao paciente como sexo e outras relacionadas ao tumor, como estadiamento, tamanho tumoral, envolvimento linfonodal e metástases à distância säo as de valor prognóstico mais expressivo.


Subject(s)
Mouth Neoplasms/epidemiology , Pharyngeal Neoplasms/epidemiology , Cohort Studies , Risk Factors
15.
PJMR-Pakistan Journal of Medical Research. 1986; 25 (4): 173-81
in English | IMEMR | ID: emr-94957

ABSTRACT

The incidence rates of carcinoma of oral cavity and pharynx were calculated for males and merles from multicentric data on the frequency of various tumours collected by Pakistan Medical search Council during 1973-74 and 197, 80 for four cities, Karachi, Hyderabad, Lahore and Peshawar. The incidence rate of carcinoma of the oral cavity in both males and females has decreased 1977--80 as compared to 1973-74 while that of carcinoma pharynx has increased


Subject(s)
Humans , Pharyngeal Neoplasms/epidemiology , Epidemiology
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