Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Medicina (B.Aires) ; 55(5/1): 431-4, 1995. graf
Article in English | LILACS | ID: lil-161619

ABSTRACT

Since a brain soluble fraction (peak II) is known to be able to inhibit synaptosomal membrane Na+, K+-ATPase activity, here we attempted to compare its effect on cellular and subcellular brain components such as synaptosomal and astrocytic membranes, as well as mitochondrial preparations. Peak II highly inhibited total ATPase in synaptosomal membranes but failed to modify enzyme activity in astrocytic and mitochondrial preparations. Findings suggest cellular and subcellular specificity of peak II on brain ATPase activity.


Subject(s)
Male , Rats , Animals , Cerebral Cortex/enzymology , Subcellular Fractions/enzymology , In Vitro Techniques , Sodium-Potassium-Exchanging ATPase/metabolism , Synaptosomes/enzymology , Astrocytes/enzymology , Subcellular Fractions/pathology , Mitochondria/enzymology , Ouabain/metabolism
SELECTION OF CITATIONS
SEARCH DETAIL