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Egyptian Journal of Pharmaceutical Sciences. 1994; 35 (1-6): 257-266
in English | IMEMR | ID: emr-32400

ABSTRACT

Starting from methyl N2[4-methylphthalazin-1-yl]dithiocarbazinate, a number of new phthalazine derivatives containing 1, 3, 4-thiadiazine and 1, 3, 4-thiadiazin-5-one rings were prepared. The structure of the new products was confirmed by spectral analysis besides synthesis via other routes. A preliminary antihypertensive evaluation revealed that most compounds possess moderate antihypertensive activity


Subject(s)
Thiadiazines/pharmacology , Antihypertensive Agents
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