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1.
Rev. med. Chile ; 150(7): 966-969, jul. 2022. ilus
Article in Spanish | LILACS | ID: biblio-1424150

ABSTRACT

Lipase hypersecretion syndrome (LHS) is a rare paraneoplastic syndrome, associated with acinar cell carcinoma of the pancreas (ACCP) in 10% to 15% of patients. Clinically, LHS manifests itself with the appearance of subcutaneous fibrocystic nodules, associated with trophic changes in the overlying skin, such as ulcers or fistulas that are difficult to manage, mainly affecting the lower extremities. Additionally, lipolysis near the joints and in the intraosseous adipose tissue can cause bilateral arthralgias, especially of the knees and ankles. We report a 57-year-old man, with a history of insulin resistance and allergic rhinitis, who presented in June 2019 with multiple subcutaneous nodules in the lower extremities, predominantly in both ankles, associated with arthralgia in that region. Additionally, a CT scan of the abdomen revealed a significant abdominal mass, measuring approximately 17 cm and in contact with the body and tail of the pancreas, pathologically compatible with an ACCP. Treatment with capecitabine was started with a favorable progression. The patient currently presents a small left lateral retro malleolar fistula, which, given the analyzes, studies and reviewed literature is concluded to be a lesion in the context of LHS.


Subject(s)
Humans , Male , Middle Aged , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/pathology , Pancreatic Neoplasms/diagnostic imaging , Skin Neoplasms , Carcinoma, Acinar Cell/complications , Carcinoma, Acinar Cell/pathology , Pancreas/pathology , Acinar Cells/pathology , Abdomen/pathology , Lipase
2.
Medwave ; 22(2): e005919, mar.2022. ilus
Article in English, Spanish | LILACS | ID: biblio-1366389

ABSTRACT

La transformación nodular angiomatoide esclerosante es una patología vascular benigna del bazo, desarrollada a partir de la pulpa roja, de etiología desconocida. Se postula que puede estar relacionada con la enfermedad por inmunoglobulina 4 y la infección por el virus de Epstein-Barr. La mayoría de los casos son asintomáticos, constituyendo hallazgos incidentales en estudios por imágenes. Presentamos el caso de un paciente masculino de 41 años con antecedentes de tiroidectomía por carcinoma papilar que consulta por fiebre. Recibió tratamiento sintomático y se realizó tomografía computarizada de abdomen por síntomas abdominales inespecíficos. La tomografía evidenció una imagen de aspecto sólido, con tenue realce periférico con el contraste que mide 62 por 52 por 51 milímetros en el polo inferior del bazo. Se realizó esplenectomía que midió 14 por 11 por 4 centímetros y pesó 284 gramos. Se identificó una formación nodular sólida, bien delimitada, con área central de aspecto fibroso, con tractos blanquecinos que delimitan áreas violáceas. La microscopía presentó nódulos coalescentes redondeados de aspecto angiomatoide, con proliferación vascular revestida por células endoteliales sin atipia, entremezclados con células ahusadas, infiltrado de linfocitos y macrófagos. El estroma entre los nódulos mostró proliferación miofibroblástica con linfocitos, plasmocitos y siderófagos. Inmunohistoquímica tuvo marcación positiva en los vasos para CD34 y CD31, sectores positivos para CD8 y negativos para CD34. Una célula positiva para inmunoglobulina 4 (IgG4) por campo de gran aumento. El estudio para Epstein-Barr por reacción en cadena de la polimerasa fue negativo. Para el diagnóstico los estudios de imagen son inespecíficos, por lo que la confirmación diagnóstica la da el estudio histopatológico. La esplenectomía es curativa sin casos reportados hasta la actualidad de transformación maligna o recidiva. No se conocen factores de riesgo y no se han comprobado factores desencadenantes, excepto la asociación de casos con IgG4 y virus de Ebstein-Barr. Por ser una entidad patológica recientemente descrita es necesario recopilar series grandes y revisar nuestros archivos, reevaluando algunos de sus diagnósticos diferenciales para lograr una mejor comprensión de la misma.


Sclerosing angiomatoid nodular transformation is a benign vascular pathology of the spleen, developed from the red pulp, of unknown etiology; it is postulated that it may be related to IgG4 disease and Epstein-Barr virus infection. Most cases are asymptomatic, constituting incidental findings in imaging studies. We present a 41-year-old male patient with a history of thyroidectomy for papillary carcinoma who consulted for fever, received symptomatic treatment and performed a computed tomography of the abdomen for nonspecific abdominal symptoms, the same evidence in the lower pole of the spleen a solid-looking image with faint Peripheral enhancement with contrast, measures 62x 52x51 mm. A splenectomy measuring 14x 11x4 cm and weighing 284 grams was performed, identifying a solid, well-defined nodular formation, with a central fibrous-looking area, with whitish tracts that delimited purplish areas. Microscopy: rounded angiomatoid-like coalescing nodules, with vascular proliferation lined by endothelial cells without atypia, interspersed with spindle cells, infiltrated by lymphocytes and macrophages. The stroma between the nodules shows myofibroblastic proliferation with lymphocytes, plasma cells, and siderophages. Immunohistochemistry: positive labeling in vessels for CD34 and CD31, positive sectors for CD8 and negative for CD34. One IgG4 positive cell per high power field. The study for Epstein-Barr by Polymesara Chain Reaction was negative. For the diagnosis, the imaging studies are nonspecific, so the diagnostic confirmation is given by the histopathological study. Splenectomy is curative with no reported cases of malignant transformation or recurrence to date. There are no known risk factors and no triggering factors have been proven, except the association of cases with IgG4 and Ebstein-Barr virus. As it is a recently described pathological entity, it is necessary to collect large series and review our files, reevaluating some of its differential diagnoses to achieve a better understanding of it


Subject(s)
Humans , Male , Adult , Histiocytoma, Benign Fibrous/diagnosis , Histiocytoma, Benign Fibrous/pathology , Epstein-Barr Virus Infections/pathology , Spleen/pathology , Herpesvirus 4, Human , Endothelial Cells/pathology , Abdomen/pathology
3.
Rev. argent. radiol ; 86(3): 190-198, 2022. graf
Article in Spanish | LILACS, BINACIS | ID: biblio-1407208

ABSTRACT

Resumen La patología arterial no ateromatosa constituye un grupo de patologías poco frecuentes, pero de gran importancia debido a su morbilidad y mortalidad asociadas. La presentación clínica de estas entidades es inespecífica, por lo que el estudio inicial con imágenes es fundamental. Debido a esto, es muy importante reconocer los signos radiológicos característicos de cada una en las diversas modalidades imagenológicas para poder sospechar y orientar el diagnóstico.


Abstract Non-atheromatous arterial pathology constitutes a group of infrequent pathologies but of great importance due to their associated morbidity and mortality. In general, the clinical presentation of these pathologies is quite nonspecific, so the clinician decides to perform imaging studies thinking of more common entities. It is for this reason that it is very important to recognize characteristic radiological signs in the various imaging modalities to be able to suspect and orient a pathology of this kind.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aneurysm, Infected/diagnostic imaging , Abdomen/pathology , Aneurysm/diagnostic imaging , Retroperitoneal Fibrosis/diagnostic imaging , Vasculitis , Abdominal Pain/diagnostic imaging , Takayasu Arteritis/diagnostic imaging , Fibromuscular Dysplasia/diagnostic imaging , Fistula/diagnostic imaging
4.
Int. j. morphol ; 38(1): 35-37, Feb. 2020. graf
Article in English | LILACS | ID: biblio-1056393

ABSTRACT

Ectopic liver tissue is a rare developmental abnormality. It is often asymptomatic and is commonly found incidentally, during surgery or autopsy. It has been reported in various abdominal and extra-abdominal sites, most often in the gall bladder. We are reporting an incidentally found mass in the left subdiafragmatic region, diagnosed as ectopic liver in abdominal CT and intraoperatively. We aim to assess the importance of imaging examinations in the differential diagnosis of intraabdominal masses ranging from benign to malignant entities and to point out that despite the low incidence of ectopic liver, it is necessary to be aware of this diagnostic possibility.


El tejido hepático ectópico es una rara anormalidad del desarrollo. A menudo es asintomático y generalmente se encuentra de manera incidental, durante la cirugía o la autopsia. Se ha informado en varios sitios abdominales y extraabdominales, con mayor frecuencia en la vesícula biliar. Reportamos el caso de una masa encontrada en la región subdiafragmática izquierda, diagnosticada como hígado ectópico en la TC abdominal e intraoperatoriamente. Nuestro objetivo fue evaluar la importancia de los exámenes por imágenes en el diagnóstico diferencial de masas intraabdominales que incluyen masas benignas como también malignas, y señalar que a pesar de la baja incidencia de hígado ectópico, es necesario tener en cuenta esta posibilidad en el diagnóstico.


Subject(s)
Humans , Aged , Choristoma/diagnostic imaging , Abdomen/pathology , Liver/pathology , Tomography, X-Ray Computed , Abdomen/diagnostic imaging
6.
Chinese Journal of Medical Instrumentation ; (6): 185-188, 2020.
Article in Chinese | WPRIM | ID: wpr-942724

ABSTRACT

As a new type of magnetic resonance imaging method, amide proton transfer (APT) imaging can detect the chemical exchange characteristics of free proprotein, peptide amide proton and water proton by water signal changes, reflecting the changes of protein and pH in tissues. In recent years, clinical research on brain tumors, multiple sclerosis, hepatic encephalopathy and cervical cancer have been carried out. It is a radiation-free and non-invasive new magnetic resonance molecular imaging technology. This study briefly reviews the principle of APT technology and its clinical application, and prospects its application prospects in children's abdominal tumors.


Subject(s)
Child , Humans , Abdomen/pathology , Amides , Magnetic Resonance Imaging , Neoplasms/diagnostic imaging , Protons
8.
Gastroenterol. latinoam ; 30(supl.1): S39-S43, 2019. tab
Article in Spanish | LILACS | ID: biblio-1116437

ABSTRACT

Fluctuating abdominal pain and bloating suggest gastrointestinal origin with multiple causes. In adults, patients fulfilling the Rome criteria for irritable bowel syndrome (IBS) have a low probability of neoplasms or intestinal inflammatory diseases. In these patients it is cost effective to request fecal calprotectin and celiac disease serology. Due to the high probability of nocebo effect, the diagnosis of sensitivity to non celiac and food allergies should require a blind rechallenge. It is recommended to evaluate other non ominous diagnostic options in a second stage if there is not good control of symptoms. In adults that do not fulfil the criteria of IBS or in adults older than 50 it is often necessary to request more studies, including endoscopic examinations. In children, abdominal pain and bloating occur frequently in the context of excessive consumption of sugar (including fructose, lactose and sorbitol). In infants it can occur in the context of congenital malformations, infant colics and food allergies. An active search for symptoms and signs of alarm is recommended. In their absence the performance of an endoscopic study is low. The use of celiac disease serology is also recommended, but the use of fecal calprotectin has the limitation that normal values are not present below age 4, so its use is not recommended under that age.


El dolor abdominal y la distensión abdominal fluctuantes sugieren origen gastrointestinal, con múltiples causas. En adultos, los pacientes que cumplen criterios de Roma para Síndrome de Intestino Irritable (SII) tienen una baja probabilidad de neoplasias o enfermedades inflamatorias intestinales (EII). En estos pacientes, es costoefectivo solicitar calprotectina fecal y serología de enfermedad celiaca. Por la alta probabilidad de efecto nocebo, el diagnóstico de sensibilidad al gluten no celiaca (SGNC) y alergias alimentarias debería requerir un rechallenge ciego. Es recomendable evaluar otras opciones diagnósticas no ominosas en una segunda etapa, si no hay buen control sintomático. En adultos que no cumplen criterios de SII o en adultos mayores de 50 años, suele requerirse más cantidad de estudios, incluyendo endoscópicos. En niños, el dolor abdominal y distensión ocurren frecuentemente en el contexto de consumo excesivo de azúcares (incluyendo fructosa, lactosa y sorbitol). En lactantes puede ocurrir también en el contexto de malformaciones congénitas, cólicos del lactante y alergia alimentaria. Se recomienda la búsqueda activa de signos y síntomas de alarma. En su ausencia el rendimiento del estudio endoscópico es bajo. También se recomienda el uso de serología de enfermedad celíaca, pero el uso de calprotectina fecal tiene la limitación de ausencia de valores de normalidad hasta los 4 años, por lo que su uso no se recomienda bajo esa edad.


Subject(s)
Humans , Child , Adult , Abdominal Pain/diagnosis , Abdominal Pain/etiology , Dilatation, Pathologic/diagnosis , Dilatation, Pathologic/etiology , Abdomen/pathology , Celiac Disease/complications , Irritable Bowel Syndrome/complications , Carbohydrate Metabolism , Food Hypersensitivity , Malabsorption Syndromes/complications
9.
Egyptian Journal of Hospital Medicine [The]. 2018; 71 (3): 2845-2850
in English | IMEMR | ID: emr-192538

ABSTRACT

Background: The International Neuroblastoma Risk Group Staging System [INRGSS] is a recent pretreatment staging system for neuroblastoma [NB], based on imaging by CT before surgery


Purpose: this study aimed to stage NB cases using CT scan, in relation to available clinicopathologic data


Patients and Methods: Twenty pathologically proven NB cases were included. All were reviewed for patients' characteristics, includingage; sex, clinical picture, LN status and metastatic spread. All cases underwent CT scan for diagnosis. Stagingwas done using IDRFs, LN status and metastatic spread according to the INRGSS and INSS when available


Results: an abdominal mass was found in 85% of cases and the suprarenal gland was the most common site of primary tumor [50% of cases]. Concerning tumor grade, 85 % of cases were poorly differentiated. LNs were positive in 70%, and metastatic spread was found in 35% of patients respectively. Staging according to the INRGSS showed that L2 was the most common stage [45% of cases], followed by M stage [35%]. L1 and MS stages were found in 15% and 5% of cases respectively. Only 7 cases had postsurgical CT scans, and were staged according to the INSS


Conclusion: it was concluded that the use of the INRGSS using CT scan, is a recent valuable pretreatment staging system, allowing accurate classification of neuroblastoma


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Multidetector Computed Tomography , Neoplasm Staging , Retrospective Studies , Abdomen/pathology
10.
Rev. bras. cir. plást ; 31(2): 252-256, 2016. ilus
Article in English, Portuguese | LILACS | ID: biblio-1570

ABSTRACT

As opções reconstrutivas para defeitos da parede anterior do tórax podem ser desafiadoras especialmente quando o defeito é extenso e sujeito a radioterapia pré-operatória. Apresenta-se caso de paciente com carcinoma ductal invasivo de mama não tratado que realizou radioterapia e quimioterapia incompleta no pré-operatória. O exame patológico revelou carcinoma ductal invasivo de 11,5 cm, grau III, com invasão linfovascular e linfonodos axilares positivos (20/20). Após a mastectomia, defeitos estendidos seguido de longa excisão de pele mediram 25 x 20 cm, sendo esses cobertos imediatamente com retalhos em abdominoplastia reversa tensionada. Trata-se do primeiro caso relatado de excisão larga de mastectomia reconstruída exclusivamente com retalhos avançados em abdominoplastia reversa e alta tensão progressiva de pontos de adesão demostrando que nos pacientes selecionados, a pele abdominal pode ser avançada superiormente com segurança e facilidade para atingir a área superior do tórax e cobrir a área com defeito significante.


Reconstructive options for anterior chest wall defects can be challenging especially when the defect is large and has been subject for preoperative radiotherapy. We report a case of a patient with a neglected large invasive ductal carcinoma of the breast who had received incomplete preoperative radiotherapy and chemotherapy. The pathology examination revealed an 11.5 cm invasive ductal carcinoma, grade III, with lymphovascular invasion and positive axillary lymph nodes (20/20). The post mastectomy large defect following wide skin excision measured 25 x 20 cm and it was immediately covered with a tensioned reverse abdominoplasty flap. To our knowledge, this is the first case reported of a wide skin excision mastectomy reconstructed solely with a reverse abdominoplasty advancement flap and progressive high-tension with quilting sutures demonstrating that, in the selected patients, abdominal skin can be safely and easily advanced superiorly to reach the upper chest area and cover an area of significant defect.


Subject(s)
Humans , Female , Middle Aged , History, 21st Century , Surgical Flaps , Abdominal Muscles , Plastic Surgery Procedures , Thoracic Wall , Carcinoma, Ductal , Diffusion of Innovation , Abdomen , Mastectomy , Surgical Flaps/surgery , Abdominal Muscles/surgery , Abdominal Muscles/pathology , Plastic Surgery Procedures/methods , Thoracic Wall/surgery , Thoracic Wall/pathology , Carcinoma, Ductal/surgery , Carcinoma, Ductal/pathology , Abdomen/surgery , Abdomen/pathology , Abdominal Neoplasms , Mastectomy/methods , Abdominal Neoplasms/surgery , Abdominal Neoplasms/complications
11.
Rev. bras. cir. plást ; 31(2): 166-171, 2016. ilus
Article in English, Portuguese | LILACS | ID: biblio-1554

ABSTRACT

INTRODUÇÃO: Um estudo retrospectivo foi realizado em 500 abdominoplastias tipo incisão transversal pubiana baixa, combinada com lipoaspiração de 2007 a 2014. Em todas, a dissecção do retalho cutâneo abdominal foi restrita, em que foram aplicados pontos de adesão em toda a extensão das regiões dissecadas. Foi ainda avaliado o uso ou não de drenos de sucção a vácuo. Em 33% dos casos não foram utilizados estes drenos e não foram também detectados sinais de seroma, comprovando a eficácia dos pontos de adesão. MÉTODOS: Em todas as abdominoplastias a via de acesso foi da região pubiana transversal baixa estendida até o nível das espinhas ilíacas anterossuperiores bilateralmente, associada à lipoaspiração nas regiões dos flancos. Após a dissecção, plicatura dos músculos retos e ressecção dos excessos cutâneos, foram aplicados pontos de adesão em toda a extensão das regiões dissecadas. RESULTADOS: A conduta com o uso sistemático dos pontos de adesão demonstrou ser eficaz, sem a necessidade do uso de drenos de qualquer natureza dada a inexistência de seroma em todos os casos operados. CONCLUSÃO: Nas abdominoplastias tipo pubiana transversal baixa, a dissecção limitada do retalho cutâneo estendida até o apêndice xifoide, associada a pontos de adesão e lipoaspiração concomitante, tem dispensado o uso de drenos a vácuo, sem a existência de seroma, além de determinar resultados gratificantes.


INTRODUCTION: A retrospective study was carried out on 500 abdominoplasties with lower pubic transverse incision combined with liposuction, performed from 2007 to 2014. In all cases, the dissection of the abdominal skin flap was restricted, with adhesion sutures applied throughout the dissected regions. The use of vacuum suction drains was also evaluated. In 33% of cases, these drains were not used, but no signs of seroma were detected, proving the efficacy of adhesion sutures. METHODS: In all abdominoplasties, the access route was the lower transverse pubic region extended up to the level of the anterior superior iliac spines bilaterally, combined with liposuction in the adjacent regions. After the dissection, plication of the rectus muscles, and resection of excess skin, adhesion sutures were applied throughout the dissected regions. RESULTS: The systematic use of adhesion sutures was efficient, without the need to use drains, given the absence of seroma in all cases. CONCLUSION: In lower pubic transverse abdominoplasty, limited dissection of the cutaneous flap extended up to the xiphoid, combined with adhesion sutures and liposuction, avoided the use of vacuum drains; no seroma developed, and the results were good.


Subject(s)
Humans , Adult , Aged , History, 21st Century , Suction , Surgical Flaps , Lipectomy , Tissue Adhesions , Cross-Sectional Studies , Retrospective Studies , Seroma , Abdomen , Subcutaneous Fat, Abdominal , Abdominoplasty , Suction/methods , Surgical Flaps/surgery , Lipectomy/methods , Tissue Adhesions/surgery , Tissue Adhesions/pathology , Cross-Sectional Studies/methods , Seroma/surgery , Dissection , Dissection/methods , Subcutaneous Fat, Abdominal/surgery , Abdominoplasty/methods , Abdomen/surgery , Abdomen/pathology
13.
Rev. bras. cir. plást ; 30(2): 196-205, 2015. ilus, tab
Article in English, Portuguese | LILACS | ID: biblio-1004

ABSTRACT

Introdução: A correção da diástase dos músculos retos do abdome é realizada principalmente pela sua plicatura, procedimento que consome muito tempo cirúrgico. O objetivo deste estudo é avaliar a eficácia e o tempo necessário para a correção da diástase dos retos do abdome comparando a plicatura com sutura contínua em plano único à plicatura em dois planos. Método: Foram incluídas 20 mulheres com história de pelo menos uma gestação. Foram randomizadas em dois grupos, um submetido à plicatura dos retos do abdome em dois planos (controle) e outro à sutura em plano único contínuo (estudo) com mononylon 2-0. Mediu-se o tempo necessário para a realização de cada uma das técnicas. Para análise estatística, foram usados os testes não paramétricos de Mann-Whitney, Friedman e Wilcoxon, considerando estatisticamente significante p < 0,05. Todas as pacientes foram submetidas à ultrassonografia previamente à cirurgia, 3 semanas e 6 meses de pós-operatório. Resultados: A plicatura do grupo estudo mostrou-se tão eficaz quanto à do grupo controle, mantendo seu resultado em longo prazo, apresentando diferença estatisticamente significante (p = 0,018) na comparação das medidas pré e pós-operatórias. No grupo estudo, porém, a plicatura consumiu menor tempo cirúrgico para ser realizada, também com diferença estatisticamente significante (p = 0,002). Conclusão: Com este estudo, pode ser concluído que tanto a sutura em dois planos como a em plano único contínuo são eficazes na correção da diástase dos retos do abdome e mantêm o resultado por longo tempo. Concluiu-se também que a técnica de sutura contínua demanda menor tempo para ser realizada.


Introduction: The correction of diastasis of the rectus abdominis muscles is primarily performed using the plication technique, which involves a surgical procedure. To evaluate the efficacy and the surgical time necessary to correct diastasis of the rectus abdominis muscles using plication and sutures in one continuous or two planes. Method: Twenty women with at least one pregnancy were included in the study. The study participants were randomized into two groups: the control group was subjected to plication in two planes, and the experimental group was subjected to plication using suture in one continuous plane with mono-nylon 2-0. The time required to perform each of these techniques was measured. For statistical analysis, the nonparametric Mann-Whitney test, Friedman test, and Wilcoxon test were used, and p-values of < 0.05 were considered statistically significant. All patients underwent ultrasonography before surgery, and at 3 weeks and 6 months postoperatively. Results: The plication technique was similarly effective in the two groups, achieving a long-term surgical outcome; however, the differences in the ultrasound measurements in the pre- and postoperative periods were statistically significant (p = 0.018). In addition, plication was performed in a significantly shorter time in the experimental group (p = 0.002). Conclusion: Sutures in one continuous plane and in two planes were effective in correcting diastasis of the rectus abdominis muscles, with the maintenance of a long-term surgical outcome. In addition, the continuous suture technique can be performed in a shorter time.


Subject(s)
Humans , Female , Adult , Middle Aged , History, 21st Century , Sutures , Efficacy , Suture Techniques , Abdominal Muscles , Rectus Abdominis , Evaluation Study , Abdominal Wall , Abdomen , Abdominoplasty , Amylases , Efficacy/methods , Suture Techniques/adverse effects , Suture Techniques/standards , Abdominal Muscles/surgery , Abdominal Muscles/pathology , Rectus Abdominis/surgery , Rectus Abdominis/pathology , Abdominal Wall/surgery , Abdominal Wall/pathology , Abdominoplasty/adverse effects , Abdominoplasty/methods , Abdomen/surgery , Abdomen/pathology , Amylases/therapeutic use
14.
Saudi Medical Journal. 2014; 35 (8): 914-914
in English | IMEMR | ID: emr-148886
15.
Scientific and Research Journal of Army University of Medical Sciences-JAUMS. 2014; 11 (4): 307-310
in Persian | IMEMR | ID: emr-138224

ABSTRACT

The aim of this study was to investigate the role of local pentoxifylline in reducing peritoneal adhesions after laparotomy performed on rats. In this randomized double-blind study, 30 male white rats weighing approximately 280-300 g were divided into two equal groups. In the control group, after induction of anesthesia and under sterile conditions, with a midline incision of 3 cm the muscles and the peritoneum opened. Animal cecum was determined by the surgeon and with one gauge, abrasions were made on antimesentric edge of cecum. Then the cecum was placed back in the abdomen and the abdomen was closed in 2 layers using nylon string "2-0" and running sutures. In case group all the above steps were repeated. The abdomen was washed with local pentoxifylline. After 2 weeks, rats were re- laparotomy. Blasting locations were studied in a previous surgery and adhesion were recorded from 0 to 3. And finally the data were analyzed by SPSS v.11 software using of statistical tests. In all of control group, adhesion was founded. In case group adhesions were founded in seven cases. Adhesion rate difference between the two groups was significant [P=0.013]. According to obtained findings from this and other similar studies, the surgeons can reduced adhesions after abdominal surgery by using local pentoxifylline


Subject(s)
Animals, Laboratory , Pentoxifylline/administration & dosage , Pentoxifylline , Rats , Double-Blind Method , Abdomen/pathology , Laparotomy
16.
Journal of Reproduction and Infertility. 2014; 15 (4): 229-232
in English | IMEMR | ID: emr-149829

ABSTRACT

The Demons-Meigs syndrome should usually be evoked in case of presence of a typical triad: abdominopelvic mass, ascites and hydrothorax. Its diagnosis appears crucial to prevent the realization of unnecessary surgical procedures. A 32-year-old woman presented in April 2012 to the emergency department of our maternity unit [General Hospital, Thiers, France] with an abdominal distension mimicking the symptoms of a pregnancy at term. Physical examination revealed a voluminous painful abdominopelvic mass, extended from the pelvis to the upper abdomen with a large right pleural effusion. Ultrasound and computed tomography showed it was a tumor measuring more than 300 mm in diameter with a right hydrothorax. Serum CA-125 level was 289 U/ml. Cytologic analysis of the pleural effusion didn't show any malignant cells. In this study, Demons-Meigs syndrome was recognized. A laparoscopico-laparotomic management permitted an aspiration of 23 liters of a brownish liquid and an unilateral adnexectomy after pleural paracentesis was performed. Frozen section demonstrated benign mucinous cystadenoma. The final histologic findings objectified intracystic intestinal type ovarian mucinous borderline tumor. After multidisciplinary consultation, the patient was re-operated one month later. The exploration didn't reveal any suspected lesions and appendectomy and omentectomy were performed. The postoperative course was uneventful. Serum CA-125 level was normal at the time of the reoperation and 24 months after the initial surgery. The preoperative recognition of a Demons-Meigs syndrome or a Demons' pseudosyndrome is essential to avoid useless surgical procedures


Subject(s)
Humans , Female , Pregnancy , Hydrothorax , Abdomen/pathology , Cystadenoma, Mucinous , Ovarian Neoplasms
17.
Rev. méd. Minas Gerais ; 23(3)jul.-set. 2013.
Article in Portuguese, English | LILACS | ID: lil-702917

ABSTRACT

A tuberculose (TB) é dos mais graves problemas de saúde humano e associa-se a pobreza, incipiência do sistema de saúde, deficiência de gestão que dificulta a diminuição de doenças de determinismo social, epidemia do vírus da imunodeficiência humana e imunodeficiência adquirida e multirresistência do M. tuberculosis. O acometimento extrapulmonar ocorre em 15% dos casos de TB e pode evoluir com amesma sintomatologia geral do acometimento pulmonar, com variações na dependência de sua localização e gravidade. Este relato apresenta paciente com hematúria e polaciúria incapacitante para a vida social, associada inicialmente à neoplasia, e determinada pela TB geniturinária, com diagnóstico após histopatologia de espécime clínico obtido da bexiga, em que o tempo longo para o diagnóstico foi determinante para grave sequela. Objetiva alertar para a TB como doença permanente no Brasil ea necessidade de ser considerada sempre como diagnóstico diferencial de doenças pulmonares ou extrapulmonares.


Tuberculosis (TB) is among the most serious human health concerns and is associated with poverty, limited availability of health care services and bad management, all of which negatively affect the possibility of reducing socially-determined diseases, such as HIV/AIDS epidemics and multidrug resistant M. tuberculosis. Extrapulmonary involvement occurs in 15% of TB cases and can develop with the same overall symptomatology of exclusively pulmonary involvement, with smaller variations depending on location and severity. This report presents a patient with hematuria and pollakiuria with incapacitating effects on social life, initially thought of as a malignancy and later identified as genitourinary TB. Diagnosis was based on histopathology of clinical specimens from the bladder. Time elapsed between onset and diagnosis led to considerable sequelae. This report aims at raising awareness of TB as a permanent concern in Brazil and of the need to always considered it as a differential diagnosis of pulmonary or extrapulmonary disease.


Subject(s)
Humans , Male , Adult , Mycobacterium tuberculosis/pathogenicity , Mycobacterium tuberculosis/ultrastructure , Tuberculosis, Male Genital/diagnosis , Tuberculosis, Male Genital/drug therapy , Abdomen/pathology , Biopsy , Diagnosis, Differential , Ethambutol , Isoniazid/therapeutic use , Pyrazinamide/therapeutic use , Rifampin/therapeutic use , Kidney , Tomography
18.
Indian J Cancer ; 2013 Jan-Mar; 50(1): 41-45
Article in English | IMSEAR | ID: sea-147318

ABSTRACT

Background: Extra gastrointestinal stromal tumors (EGIST) are uncommon compared to their gastrointestinal counterparts. EGISTs involve omentum, mesentery, retroperitoneum, pancreas, and pelvis. Materials and Methods: Ten EGISTs were analyzed in this study from January 1995 to November 2011. They were analyzed with respect to clinical features, imageological, histopathological, and immunohistochemical findings. The immunohistochemical stains used were Smooth muscle actin (SMA), Desmin, S-100 protein, CD34 and CD-117. Results: There was slight female preponderance with wide age range. Four of the tumors were in retroperitoneum, three in mesentery, and two in omentum and one in pelvis. Histopathologically majority were spindle cell tumors. Immunohistochemically CD117 was consistently positive followed by CD34. Smooth muscle actin was positive in eight cases, S-100 protein and desmin were positive in two cases each. Conclusion: EGISTs are rare and should be considered in the differential diagnosis of the mesenchymal tumors and immunohistochemistry helps to confirm the diagnosis. Further study with better follow-up is desired to characterize these uncommon tumors.


Subject(s)
Abdomen/pathology , Actins/metabolism , Adult , Aged , Antigens, CD34/metabolism , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Male , Middle Aged , Neoplasms, Connective Tissue/diagnosis , Neoplasms, Connective Tissue/metabolism , Neoplasms, Connective Tissue/pathology , Peritoneal Neoplasms/diagnosis , Peritoneal Neoplasms/metabolism , Peritoneal Neoplasms/pathology , Proto-Oncogene Proteins c-kit/metabolism , Radiography, Abdominal , Sarcoma/diagnosis , Sarcoma/metabolism , Sarcoma/pathology , Tertiary Care Centers , Young Adult
19.
Esculapio. 2013; 9 (1): 47-53
in English | IMEMR | ID: emr-143133

ABSTRACT

Port site infections after laparoscopic surgery are a known complication and take away a lot of benefits attributed to the minimal access approach. Detecting the flora responsible is essential and atypical mycobacteria must also be considered. This case series is a compilation of the accounts of ten different patients with chronic granulomatous inflammation of the anterior abdominal wall presenting with port site discharging sinuses and lumps after laparoscopic surgery. Atypical mycobacterial infections must be considered in patients with persistent wound infections after laparoscopic surgery and warrants a revision of the high level disinfection [HLD] process.


Subject(s)
Humans , Female , Laparoscopy/adverse effects , Abdomen/pathology , Granuloma/diagnosis , Surgical Wound Infection/diagnosis , Disinfection , Postoperative Complications , Mycobacterium tuberculosis
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