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Braz. J. Anesth. (Impr.) ; 73(6): 725-735, Nov.Dec. 2023. tab, graf
Article in English | LILACS | ID: biblio-1520381


Abstract Background: Ultra-low-dose Spinal Anesthesia (SA) is the practice of employing minimal doses of intrathecal agents so that only the roots that supply a specific area are anesthetized. The aim of this study was to compare the effectiveness and safety of ultra-low-dose spinal anesthesia with that of Perineal Blocks (PB). Methods: A two-arm, parallel, double-blind randomized controlled trial comparing two anesthetic techniques (SA and PB) for hemorrhoidectomy and anal fistula surgery was performed. The primary outcomes were postoperative pain, complementation and/or conversion of anesthesia, and hemodynamic changes. Results: Fifty-nine patients were included in the final analysis. The mean pain values were similar in the first 48 h in both groups (p > 0.05). The individuals allocated to the SA group did not need anesthetic complementation; however, those in the PB group required it considerably (SA group, 0% vs. PB group, 25%; p = 0.005). Hemodynamic changes were more pronounced after PB: during all surgical times, the PB group showed lower MAP values and higher HR values (p < 0.05). Postoperative urinary retention rates were similar between both groups (SA group 0% vs. PB group 3.1%, p = 0.354). Conclusion: SA and PB are similarly effective in pain control during the first 48 h after hemorrhoidec-tomy and anal fistula surgery. Although surgical time was shorter among patients in the PB group, the SA technique may be preferable as it avoids the need for additional anesthesia. Furthermore, the group that received perineal blocks was under sedation with a considerable dose of propofol.

Humans , Rectal Fistula/surgery , Anesthesia, Spinal/methods , Anesthetics , Pain, Postoperative/prevention & control , Anesthesia, Local
Braz. J. Anesth. (Impr.) ; 73(3): 258-266, May-June 2023. tab, graf
Article in English | LILACS | ID: biblio-1439614


Abstract Background: Service quality in anesthesiology has been frequently measured by morbidity and mortality. This measure increasingly considers patient satisfaction, which is the result of care from the client's perspective. Therefore, anesthesiologists must be able to build relationships with patients, provide understandable information and involve them in decisions about their anesthesia. This study aimed to evaluate the peri-anesthetic care provided by the anesthesia service in an ambulatory surgery unit using the Heidelberg Peri-anaesthetic Questionnaire. Methods: This cross-sectional study used the Heidelberg Peri-anaesthetic Questionnaire to evaluate 1211 patients undergoing ambulatory surgery. We selected questions that showed a greater degree of dissatisfaction and correlated them with patient characterization data (age, sex, education, and ASA physical status), anesthesia data (type, time, and prior experience), and surgical specialty. Results: Questions in which patients tended to show dissatisfaction involved fear of anesthesia and surgery, feeling cold, the urgent need to urinate, pain at the surgical site, and the team's level of concern and speed of response in relieving the patient's pain. Conclusion: The Heidelberg Peri-anaesthetic Questionnaire proved to be a useful tool in identifying points of dissatisfaction, mainly fear of anesthesia and surgery, feeling cold, the urgent need to urinate, pain at the surgical site, and the team's level of concern and speed of response in relieving the patient's pain in the population studied. These were correlated with patient, anesthesia, and surgical variables. This allows the establishment of priorities at the different points of care, with the ultimate goal of improving patient satisfaction regarding anesthesia care.

Humans , Anesthesia , Anesthesiology , Anesthetics , Pain , Cross-Sectional Studies , Surveys and Questionnaires , Patient Satisfaction
Braz. J. Anesth. (Impr.) ; 73(2): 227-229, March-Apr. 2023. graf
Article in English | LILACS | ID: biblio-1439582


Abstract A male patient was scheduled for urgent amputation of his right forearm. His right forearm was stuck inside the insertion slot of a meat grinder, resulting in severe pain to his injured arm. His upper body could not move to sit in a semi-upright position. An endotracheal tube was successfully placed after rapid sequence intubation using a video laryngoscope from behind the patient on the first attempt. This case report is the first documentation of successful anesthetic induction with subsequent endotracheal intubation using a video laryngoscope from behind an injured patient whose upper body was upright with limited positioning.

Humans , Male , Laryngoscopes , Anesthetics , Forearm/surgery , Sitting Position , Intubation, Intratracheal/methods , Laryngoscopy/methods
Braz. J. Anesth. (Impr.) ; 73(2): 217-219, March-Apr. 2023. tab
Article in English | LILACS | ID: biblio-1439596


Abstract Emery-Dreifuss Muscular Dystrophy is a very rare type of muscular dystrophy, associated with contractures, atrophy, and muscle weakness, besides cardiomyopathy with severe arrhythmias. Published studies focusing on this disorder are scarce. We describe the anesthetic management of a male patient with Emery-Dreifuss Muscular Dystrophy, to be submitted to umbilical and inguinal hernioplasty and hydrocele repair under epidural anesthesia. The anesthesia approach enabled us to circumvent the patient's susceptibility to malignant hyperthermia and his potentially difficult airway, in addition to maintaining hemodynamic stability. The day after surgery the patient resumed walking, and two days later he was discharged from the hospital.

Humans , Male , Muscular Dystrophy, Emery-Dreifuss/complications , Muscular Dystrophy, Emery-Dreifuss/pathology , Anesthesia, Epidural , Anesthetics , Malignant Hyperthermia
Braz. J. Anesth. (Impr.) ; 73(2): 138-144, March-Apr. 2023. tab, graf
Article in English | LILACS | ID: biblio-1439597


Abstract Introduction Malignant Hyperthermia (MH) is an inherited hypermetabolic syndrome triggered by exposure to halogenated anesthetics/succinylcholine. The lack of knowledge regarding this condition might be associated with the rare occurrence of MH reaction and symptoms. Methods This observational study evaluated 68 patients from 48 families with confirmed or suspected MH susceptibility due to medical history of MH reaction or idiopathic increase of creatine kinase or MH-related myopathies. Participants were assessed by a standardized questionnaire and submitted to physical/neurological examination to assess the characteristics of patients with MH, their knowledge about the disease, and the impact suspected MH had on their daily lives. Results Suspected MH impacted the daily life of 50% of patients, creating difficulties in performing surgical/clinical/dental treatment and problems related to their family life/working/practicing sports. The questionnaire on MH revealed a correct answer score of 62.1 ± 20.8 (mean ± standard deviation) on a scale 0 to 100. Abnormal physical/neurological examination findings were detected in 92.6% of susceptible patients. Conclusions Suspected MH had impacted the daily lives of most patients, with patients reporting problems even before MH investigation with IVCT. Patients showed a moderate level of knowledge about MH, suggesting the need to implement continuing education programs. MH susceptible patients require regular follow-up by a health team to detect abnormalities during physical and neurological examination.

Humans , Anesthetics , Malignant Hyperthermia/diagnosis , Succinylcholine , Syndrome , Disease Susceptibility
Alerta (San Salvador) ; 6(1): 61-69, ene. 30, 2023. ilus
Article in Spanish | BISSAL, LILACS | ID: biblio-1413696


La ecografía es una herramienta segura, portátil, económica y de fácil acceso. Los médicos anestesiólogos pueden beneficiarse con esta herramienta diagnóstica rápida y precisa en su práctica habitual. Existen múltiples áreas potenciales donde la ecografía desempeña un papel importante, para la orientación de intervenciones a ciegas e invasivas, el diagnóstico de condiciones críticas y la evaluación de posibles variaciones anatómicas que pueden conducir a la modificación del plan anestésico. Esta revisión narrativa describe las principales aplicaciones de la ecografía en anestesia, las técnicas ecoguiadas y las tendencias actuales del manejo anestésico perioperatorio del paciente quirúrgico. Se realizó una búsqueda en las bases de datos PubMed y Cochrane, se incluyeron artículos originales, estudios aleatorizados y de revisión, en español y en inglés, publicados entre 2017-2021. El uso de ecografía ha entrado en el campo de la medicina del dolor, anestesia regional y del intervencionismo analgésico durante la última década, e incluso es el estándar de la práctica, por tanto, la capacitación y un adecuado aprendizaje en la ecografía deben ser parte del plan de estudios de cualquier programa de anestesiología

Ultrasound is a safe, portable, inexpensive, and easily accessible tool. Anesthesiologists can benefit from this fast and accurate diagnostic tool in their routine practice. There are multiple potential areas where ultrasound plays an important role in the guidance of blind and invasive interventions, diagnosis of critical conditions, and assessment of possible anatomical variations that may lead to modification of the anesthetic plan. This narrative review describes the main applications of ultrasound in anesthesia, ultrasound-guided techniques, and current trends in the perioperative anesthetic management of the surgical patient. A search was conducted in PubMed and Cochrane databases. Original articles, randomized and review studies in Spanish and English published between 2017-2021 were included. The use of ultrasound has entered the field of pain medicine, regional anesthesia, and interventional analgesia during the last decade and is even the standard of practice. Therefore, training and adequate learning in ultrasound should be part of the curriculum of any anesthesiology program

Ultrasonography , Anesthesia , Pain , Patients , Anesthetics
Braz. J. Anesth. (Impr.) ; 73(4): 500-502, 2023. graf
Article in English | LILACS | ID: biblio-1447618


Abstract Acquired angioedema with C1 inhibitor deficiency (AAE-C1INH) is a very rare condition of bradykinin-mediated angioedema. One of its major complications is potentially life-threatening, laryngeal edema. We report a 53-year-old woman with AAE-C1INH proposed for an elective broncofibroscopy. The direct stimulation caused by broncofibroscopy poses a high risk of angioedema, thus presenting an anesthetic challenge. Due to the risk of death, it is essential to adopt preventive measures. Short-term prophylaxis was performed, and the acute treatment was readily available. A well-structured multidisciplinary periprocedural plan makes it possible to safely approach the airway, in a remote area of the hospital.

Humans , Female , Young Adult , Angioedemas, Hereditary/therapy , Anesthetics , Angioedema
Braz. J. Anesth. (Impr.) ; 73(4): 393-400, 2023. tab, graf
Article in English | LILACS | ID: biblio-1447619


Abstract Background Reliable devices that quantitatively monitor the level of neuromuscular blockade after neuromuscular blocking agents' administration are crucial. Electromyography and acceleromyography are two monitoring modalities commonly used in clinical practice. The primary outcome of this study is to compare the onset of neuromuscular blockade, defined as a Train-Of-Four Count (TOFC) equal to 0, as measured by an electromyography-based device (TetraGraph) and an acceleromyography-based device (TOFscan). The secondary outcome was to compare intubating conditions when one of these two devices reached a TOFC equal to 0. Methods One hundred adult patients scheduled for elective surgery requiring neuromuscular blockade were enrolled. Prior to induction of anesthesia, TetraGraph electrodes were placed over the forearm of patients' dominant/non-dominant hand based on randomization and TOFscan electrodes placed on the contralateral forearm. Intraoperative neuromuscular blocking agent dose was standardized to 0.5−1 of rocuronium. After baseline values were obtained, objective measurements were recorded every 20 seconds and intubation was performed using video laryngoscopy once either device displayed a TOFC = 0. The anesthesia provider was then surveyed about intubating conditions. Results Baseline TetraGraph train-of-four ratios were higher than those obtained with TOFscan (Median: 1.02 [0.88, 1.20] vs. 1.00 [0.64, 1.01], respectively, p < 0.001). The time to reach a TOFC = 0 was significantly longer when measured with TetraGraph compared to TOFscan (Median: 160 [40, 900] vs. 120 [60, 300] seconds, respectively, p < 0.001). There was no significant difference in intubating conditions when either device was used to determine the timing of endotracheal intubation. Conclusions The onset of neuromuscular blockade was longer when measured with TetraGraph than TOFscan, and a train-of-four count of zero in either device was a useful indicator for adequate intubating conditions. Clinical trial number and registry URL NCT05120999,

Humans , Adult , Neuromuscular Nondepolarizing Agents , Neuromuscular Blockade , Neuromuscular Blocking Agents , Prospective Studies , Neuromuscular Monitoring , Rocuronium , Androstanols , Anesthetics
Acta cir. bras ; 38: e384323, 2023. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1519873


Purpose: The primary objective of this study was to compare the WALANT (wide awake, local anesthesia, no tourniquet) technique with local anesthesia associated with sedation in relation to pain intensity for minor hand surgical procedures. The secondary objective was to evaluate the need for analgesic complementation. Methods: A prospective, randomized, comparative, and clinical study was carried out. The sample size in each group was determined after statistical evaluation of the results of a pilot project. The participants were allocated to one of two groups; those in group 1 were submitted to the WALANT technique, and those in group 2, to local anesthesia associated with sedation, for elective surgery. The surgical procedures were carpal tunnel syndrome, De Quervain's tenosynovitis, synovial cyst, finger cyst, and trigger finger. Pain intensity, need for complementation and evolution to complex regional pain syndrome were evaluated. Results: There was no difference between groups in pain intensity after WALANT and need for intraoperative complementation. There was no significant difference in the amount of opioid applied postoperatively between the groups. There was no difference between groups regarding comfort during surgery. There was no difference in adverse effects and complications between the groups. Hematoma was the most frequent adverse event. No severe adverse events were observed. Conclusions: The WALANT technique promoted an analgesic effect similar to that of local anesthesia associated with sedation, without increasing adverse effects.

Pain Measurement , Epinephrine , Hand/surgery , Anesthesia, Local , Anesthetics , Lidocaine
Braz. J. Anesth. (Impr.) ; 72(6): 826-828, Nov.-Dec. 2022.
Article in English | LILACS | ID: biblio-1420612


Abstract Mutations in SCN8A gene lead to changes in sodium channels in the brain, which are correlated with severe epileptic syndrome. Due to the rarity, there are few studies that support anesthesia in that population. The present study aims to report alternatives to inhalation anesthesia at epileptic encephalopathy. Case report: Male, 4 years old, with SCN8A encephalopathy with surgical indication of orchidopexy. Neuroaxis block was performed and dexmedetomidine was used as a pre-anesthetic and sedation. The anestheticsurgical act was uneventful. Conclusion: The association of neuraxial block and dexmedetomidine proved to be a viable alternative for surgery in patients with SCN8A encephalopathy.

Humans , Male , Child, Preschool , Dexmedetomidine , Epilepsy , Anesthetics , NAV1.6 Voltage-Gated Sodium Channel/genetics , Mutation
Braz. J. Anesth. (Impr.) ; 72(6): 813-815, Nov.-Dec. 2022.
Article in English | LILACS | ID: biblio-1420629


Abstract Lung transplantation is the last resort for end-stage lung disease treatment. Due to increased survival, lung recipients present an increased likelihood to be submitted to anesthesia and surgery. This case report describes a 23-year-old female patient with history of lung transplantation for cystic fibrosis, with multiple complications, and chronic kidney disease, and who underwent kidney transplantation under general anesthesia. Understanding the pathophysiology and changes related to immunosuppressive therapy is essential to anesthetic technique planning and safety, and for perioperative management. The success of both anesthesia and surgery requires a qualified multidisciplinary team due to the rarity of the clinical scenario and high incidence of associated morbidity and mortality.

Humans , Female , Adult , Young Adult , Kidney Transplantation , Lung Transplantation/methods , Cystic Fibrosis/surgery , Cystic Fibrosis/complications , Anesthetics , Anesthesia, General
Rev. cuba. anestesiol. reanim ; 21(3): e829, sept.-dic. 2022. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1408171


Introducción: La comodidad durante la colonoscopia es una condición importante si se quiere que el paciente acepte procedimientos repetidos. Por lo tanto, se necesita de una buena sedación que pudiera combinar la analgesia con amnesia. Objetivo: Describir la utilidad de la analgosedación balanceada con propofol/fentanilo en colonoscopia ambulatoria. Métodos: Se realizó un estudio observacional descriptivo longitudinal prospectivo en pacientes a los que se les realizó colonoscopia de forma ambulatoria en el Hospital General Universitario Dr. Gustavo Aldereguía Lima en el período entre enero de 2017 y diciembre de 2018. Resultados: El 34,2 por ciento de los pacientes tenía entre 50 y 59 años, el 62,9 por ciento eran mujeres. El 73,3 por ciento de los pacientes se clasificó como ASA II según el estado físico. Los valores medios de frecuencia cardiaca y tensión arterial media tuvieron una disminución ligera después de aplicada la anestesia y se mantuvieron constantes en el resto de los momentos evaluados. Los valores medios de saturación de oxígeno de la hemoglobina se mantuvieron relativamente constantes en todos los momentos y resultaron algo superiores a la llegada del paciente a recuperación. La calidad de la sedación fue adecuada en 86,2 por ciento de los pacientes. La calidad de la analgesia y la recuperación fue buena en 88,4 por ciento y 96,2 por ciento , respectivamente. Se presentaron complicaciones en el 16,5 por ciento de los pacientes. Conclusiones: La analgosedación con propofol y fentanilo resultó una alternativa anestésica de utilidad en los pacientes a los que se les realizó colonoscopia ambulatoria con gran estabilidad hemodinámica en la serie estudiada(AU)

Introduction: Comfort during colonoscopy is an important condition if the patient is expected to accept repeated procedures. Therefore, good sedation that could combine analgesia with amnesia is needed. Objective: To describe the usefulness of balanced analgosedation with propofol/fentanyl in outpatient colonoscopy. Methods: A prospective, longitudinal, descriptive and observational study was carried out with patients who received outpatient colonoscopy at Dr. Gustavo Aldereguía Lima General University Hospital in the period between January 2017 and December 2018. Results: 34.2 percent of the patients were between 50 and 59 years old, while 62.9 percent were women. 73.3 percent of patients were classified as ASA II, according to their physical status. The mean values for heart rate and mean arterial blood pressure had a slight decrease after anesthesia was applied and remained constant for the rest of the evaluated times. The mean values of hemoglobin-oxygen saturation remained relatively constant at all the evaluated times and were slightly higher on the patient's arrival to recovery. The quality of sedation was adequate in 86.2 percent of the patients. The quality of analgesia and recovery was good in 88.4 percent and 96.2 percent, respectively. Complications occurred in 16.5 percent of the patients. Conclusions: Analgosedation with propofol and fentanyl proved to be a useful anesthetic alternative in patients undergoing outpatient colonoscopy, with high hemodynamic stability in the studied series(AU)

Humans , Male , Female , Propofol/administration & dosage , Fentanyl , Anesthetics , Deep Sedation/standards
Braz. J. Anesth. (Impr.) ; 72(5): 629-636, Sept.-Oct. 2022. tab, graf
Article in English | LILACS | ID: biblio-1420601


Abstract Background and objectives We aimed to investigate the effects of two different anesthetic techniques in our patients who underwent transcatheter aortic valve implantation (TAVI). Methods In this study, 303 patients who underwent TAVI procedure with a diagnosis of severe aortic stenosis between January 1, 2012 and December 31, 2018 were retrospectively evaluated. The patients were divided according to the type of anesthesia given during each procedure as; general anesthesia (GA), local anesthesia (LA). Results LA was preferred in 245 (80.8%) of 303 patients who underwent TAVI, while GA was preferred in 58 patients (19.1%). Median ages ​​of our patients who received LA and GA were 83 and 84, respectively. The procedure and anesthesia durations of the patients in the GA group were longer than the LA group (p< 0.00001, p< 0.00001, respectively). Demographic and pre-operative clinical data were similar in comparison between two groups (p> 0.05) except for peripheral artery disease. Hypertension was the most common comorbidity in both groups. While the number of inotrope use was significantly higher in patients who received GA (p< 0.00001), no significant differences were found between LA and GA patients in terms of major complications and mortality (p> 0.05). Intensive care and hospital stays were significantly shorter in the LA group (p= 0.001, p= 0.023, respectively). Conclusion The anesthetic technique of TAVI procedure did not have a significant effect on outcomes including; complications, mortality and success of the procedure. LA provides shorter duration of procedure and hospital stay.

Humans , Aortic Valve Stenosis/surgery , Retrospective Studies , Risk Factors , Anesthetics , Postoperative Complications/etiology , Treatment Outcome , Transcatheter Aortic Valve Replacement/adverse effects , Transcatheter Aortic Valve Replacement/methods , Anesthesia, General , Anesthesia, Local
Int. j. morphol ; 40(3): 627-631, jun. 2022. ilus, tab
Article in English | LILACS | ID: biblio-1385652


SUMMARY: The goal of ultrasound-guided suprainguinal fascia iliaca block (USG-SFIB) is anesthetic spread to three nerves, which are lateral femoral cutaneous nerve (LFCN), femoral nerve (FN), and obturator nerve (ON). The 90 % minimum effective volume (MEV90) for USG-SFIB is each result of studied showed the successful block and effect in various volume for block. So, Thus, the study purposes to demonstrate the efficiency of the effective volume (MEV90,62.5 ml) for USG-SFIB and confirm the staining of dye in connective tissue of nerve (nerve layer) that focused on the obturator nerve by histological examination in cadavers. The histological result showed the dye staining on the nerve layer of the ON in epineurium (100 %) and un-staining perineurium & endoneurium. Therefore, the minimal effective volume (MEV) is effective for USG-SFIB. Moreover, dye stain at the epineurium of stained obturator nerve only.

RESUMEN: El objetivo del bloqueo de la fascia ilíaca suprainguinal guiado por ecografía (USG-SFIB) es la propagación anestésica a tres nervios, cutáneo femoral lateral, femoral y obturador. El volumen efectivo mínimo del 90 % (MEV90) para USG-SFIB en cada uno de los resultados mostró el bloqueo exitoso y el efecto en varios volúmenes por bloqueo. Por lo tanto, el estudio tuvo como objetivo demostrar la eficiencia del volumen efectivo (MEV90,62.5 ml) para USG-SFIB y confirmar la tinción de tinte en el tejido conectivo del nervio, el cual se centró en el nervio obturador a través del examen histológico en cadáveres. El resultado histológico mostró tinción de colorante en el epineuro (100 %) del nervio obturador, sin embargo no hubo tinción del perineuro y endoneuro. Por lo tanto, el volumen efectivo mínimo (MEV) es efectivo para USG-SFIB.

Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Fascia/drug effects , Anesthetics/administration & dosage , Nerve Block , Cadaver
Braz. J. Vet. Res. Anim. Sci. (Online) ; 59: e188652, fev. 2022. tab
Article in English | LILACS, VETINDEX | ID: biblio-1363174


Sedative and antinociceptive effects of two anesthetic protocols in black-tufted marmosets were compared in this study. Twenty-six marmosets underwent chemical immobilization for physical examination, blood sampling, tattooing, and microchipping. Animals were randomly treated with S-(+)-ketamine (10 mg/kg) and midazolam (1 mg/kg) (KM) or fentanyl (12.5 µg/kg) and droperidol (625 µg/kg) (FD) given by intramuscular injection. Heart and respiratory rates were recorded. Sedation, antinociception, muscle relaxation, posture, auditory, and visual responses were evaluated using a scoring system. Sedation in KM was achieved faster (p < 0.001) and lasted for a shorter period of time (p = 0.0009). KM was similar to FD in its cardiorespiratory effects, auditory and visual responses. Both protocols promoted adequate sedation to allow manipulation. Animals in KM assumed lateral recumbency while animals in FD maintained a quadrupedal posture during evaluation. FD produced less intense sedation and muscle relaxation but a higher degree of antinociception compared to KM and is suitable for procedures that require analgesia in black-tufted marmosets.(AU)

O presente estudo comparou os efeitos cardiorrespiratórios, sedativos e antinociceptivos de dois protocolos anestésicos em saguis-de-tufo-preto (Callithrix penicillata). Vinte e seis saguis foram submetidos à contenção química para exame físico, coleta de sangue, tatuagem de identificação e microchip. Os animais foram tratados aleatoriamente com a associação de S-(+)-cetamina (10 mg/kg) e midazolam (1 mg/kg) (KM) ou fentanil (12,5 µg/kg) e droperidol (625 µg/kg) (FD), administrados por injeção intramuscular. Foram avaliadas frequência cardíaca, frequência respiratória, sedação, antinocicepção, relaxamento muscular, postura e resposta ao estímulo auditivo e visual. A sedação em KM foi alcançada mais rapidamente (p <0,001) e teve um tempo hábil mais curto (p = 0,0009). KM foi semelhante a FD nos efeitos cardiorrespiratórios, respostas auditivas e visuais. Os dois protocolos promoveram sedação adequada para manipulação. Os animais do grupo KM permaneceram em decúbito lateral durante a avaliação, enquanto os animais em FD mantiveram postura quadrupedal. FD resultou em sedação e relaxamento muscular de menor intensidade, porém com maior escore de antinocicepção em comparação com KM, sendo adequada para procedimentos que requerem analgesia em saguis-de-tufo-preto.(AU)

Animals , Midazolam/administration & dosage , Callithrix , Fentanyl , Droperidol/administration & dosage , Ketamine/administration & dosage , Anesthetics/administration & dosage , Injections, Intramuscular
Semina cienc. biol. saude ; 43(1): 167-176, jan./jun. 2022. ilus, tab
Article in Portuguese | LILACS | ID: biblio-1354480


Animais presentes em zoológicos frequentemente necessitam de captura e anestesia para a realização de procedimentos clínicos e cirúrgicos. A anestesia total intravenosa apresenta vantagens como redução do estresse cirúrgico e menor depressão cardiovascular e respiratória. Entretanto, ainda são escassas as pesquisas dedicadas dentro deste contexto. Nesse sentido, o objetivo deste relato foi avaliar o protocolo anestésico empregado, visando um procedimento seguro e passível de reversão para a espécie silvestre selecionada. Acompanhou-se a anestesia de um leão (Panthera leo), macho, adulto, proveniente do Zoológico Municipal de Curitiba, submetido a procedimento endodôntico. A medicação pré-anestésica constituiu-se de dexmedetomidina (6 µg/kg), metadona (0,2 mg/kg), midazolam (0,1 mg/kg) e tiletamina-zolazepam (1,2 mg/kg). A indução foi realizada com propofol (1,5 mg/kg) e o animal foi intubado. Visando promover analgesia local, foi realizado bloqueio infraorbitário esquerdo com 5 mL de lidocaína a 2%. A manutenção foi realizada por meio do fornecimento de propofol (0,02-0,1 mg/kg/h), dexmedetomidina (0,5 µg/kg/h) e remifentanil (5 µg/kg/h). O paciente apresentou sedação profunda e foi mantido em plano anestésico cirúrgico; todos os parâmetros fisiológicos monitorados permaneceram estáveis durante todo o procedimento. Após 55 minutos de anestesia o paciente apresentava sustentação espontânea da cabeça, quando foi novamente transportado ao zoológico para soltura no recinto. A ambulação foi considerada normal pelos observadores no zoológico seis horas após a anestesia. Pôde-se concluir que o protocolo realizado se mostrou tanto eficaz quanto seguro para a referida espécie encaminhada ao procedimento em questão.

Zoo animals often require capture and anesthesia in order to undergo clinical and surgical procedures. Total intravenous anesthesia has advantages such as reduced surgical stress and less cardiovascular and respiratory depression. However, specific research on this matter is still scarce. Therefore, the present report aims to evaluate the anesthetic protocol employed, seeking a safe and reversible procedure for the selected wild species. A male adult lion (Panthera leo), from the Zoológico Municipal de Curitiba, was subjected to an endodontic anesthesia, under close monitoring. The pre-anesthetic medication consisted of dexmedetomidine (6 µg/kg), methadone (0.2 mg/kg), midazolam (0.1 mg/kg) and tiletamine-zolazepam (12 mg/kg). Induction was performed with propofol (1 mg/kg) and the animal was intubated. In order to promote local analgesia, a left infraorbital block was implemented with 5 mL of 2% lidocaine. Maintenance was undertaken by supplying propofol (0.02-0.1 mg/kg/min), dexmedetomidine (0.5 µg/kg/h) and remifentanil (5 µg/kg/h). The patient exhibited deep sedation and followed the surgical anesthetic plan; all the monitored physiological parameters remained stable throughout the procedure. After 55 minutes of anesthesia the patient showed spontaneous head support, when it was transported back to the zoo. The ambulation was considered normal by the zoo observers 6 hours after the anesthesia. It was concluded that the protocol was both effective and safe for the referred species undergone the procedure reported.

Animals , Preanesthetic Medication , Tiletamine , Zolazepam , Propofol , Dexmedetomidine , Analgesia , Anesthesia , Anesthesia, Intravenous , Anesthetics , Animals, Zoo
Belo Horizonte; s.n; 2022. 148 p.
Thesis in Portuguese | LILACS, InstitutionalDB, BDENF, ColecionaSUS | ID: biblio-1434340


Introdução: a ocorrência de complicações no paciente em Sala de Recuperação Pós-Anestésica está diretamente relacionada às condições clínicas pré-operatórias, à extensão e tipo de cirurgia, às intercorrências cirúrgicas e anestésicas, bem como à efetividade das medidas terapêuticas aplicadas. Objetivo: construir e validar escala de Avaliação de Enfermagem para o paciente na Sala de Recuperação Pós-Anestésica. Metodologia: trata-se de uma pesquisa metodológica, para construção e validação de uma escala denominada "Avaliação de Enfermagem para o paciente na Sala de Recuperação Pós-Anestésica - AEPRA", desenvolvida em dois campos, o primeiro, um Hospital da Rede Pública Federal de Belo Horizonte, e o segundo, um Hospital da rede Municipal de Sete Lagoas. A escolha dos itens que compuseram a escala foi baseada nos resultados evidenciados em síntese de literatura, a saber: temperatura axilar, frequência cardíaca, respiração, pressão arterial sistólica, saturação periférica de oxigênio, consciência, movimentação, dor, náusea e vômito e ferida operatória, onde cada um dos dez (10) itens tem o escore mínimo de um (1) e o máximo de quatro (4), assim o escore pode variar de 10 a 40 pontos. A validação aparente e de conteúdo foi realizada com dez (10) juízes, por meio dos Índices de Validade de Conteúdo. A análise de confiabilidade foi realizada por meio do Coeficiente de Correlação Intraclasse. Foram avaliados cada item que compôs a escala, bem como globalmente, por dois interobservadores, separadamente e concomitantemente. Para validade de critério concorrente e validação de critério preditiva, realizou-se o cálculo amostral, e a aplicação da escala em 86 pacientes, adultos, com classificação de American Society of Anesthesiologists I, II ou III, submetidos a diversos tipos de procedimentos anestésicos-cirúrgicos. Para validação de critério concorrente, considerou-se como padrão ouro a Escala de Aldrete e Kroulik, e a análise por meio da correlação de Spearman. Para validade de critério preditivo da complicação foi utilizado o método Generalized Equations Estimating. A verificação do melhor ponto de corte do escore total para a alta, foram avaliadas as curvas Receiver Operating Characteristic e a Area Under the Curve. Resultados: a validação aparente e de conteúdo obteve a média global de 89% e a análise de confiabilidade por meio do Coeficiente de Correlação Intraclasse obteve confiabilidade global de 0,91. Quanto a validade de critério, foi realizada a comparação entre a escala proposta e a padrão ouro, sendo que houve correlação significativa (Valor-p <0,001) e positiva, com "r" igual ou maior 0,5, para todos os parâmetros e entre o total de cada uma das escalas; exceto para o parâmetro ventilação/respiração (Valor-p = 0,397). Em relação à validade de critério preditiva, a análise multivariada revelou fortemente a relação dos parâmetros temperatura, pressão arterial sistólica, saturação periférica de oxigênio e mobilidade como ocorrência de complicações. Por meio das curvas Receiver Operating Characteristic e a Area Under the Curve, tem-se nos pontos de corte 39 (AUC = 0,667) e 38 (AUC = 0,594), evidenciando os melhores pontos de corte. Conclusão: A escala de Avaliação de Enfermagem para o paciente na Sala de Recuperação Pós-Anestésica, é um instrumento confiável e válido para avaliação do paciente na Sala de Recuperação Pós-Anestésica.

Introduction: the occurrence of complications in patients in the Post-Anesthetic Recovery Room is directly related to preoperative clinical conditions, the extent and type of surgery, surgical and anesthetic complications, as well as the effectiveness of therapeutic measures applied. Objective: build and validate the Nursing Assessment Scale for patient in Post-Anesthetic Recovery Room. Methodology: this is a methodological research, for the construction and validation of a scale called "Nursing Assessment for patient in Post-Anesthetic Recovery Room - NAPPARR", developed in two fields, first, a Hospital of the Federal Public Network. of Belo Horizonte, and second, a Hospital Municipal of Sete Lagoas. The choice of items that made up the scale was based on the results evidenced in a synthesis of literature, namely: axillary temperature, heart rate, breathing, systolic blood pressure, peripheral oxygen saturation, consciousness, movement, pain, nausea and vomiting and surgical wound, each of ten (10) items has a minimum score of one (1) and a maximum of four (4), so the score can vary from 10 to 40 points. The face and content validation was performed with ten (10) judges, using Content Validity Indexes. Reliability analysis was performed using the Intraclass Correlation Coefficient. Each item that composed the scale was evaluated, as well as globally, by two interobservers, separately and concomitantly. For concurrent criterion validity and predictive criterion validation, the sample size calculation was performed, and the scale was applied to 86 adult patients classified as American Society of Anesthesiologists I, II or III, who underwent different types of anesthetic procedures- surgical. For validation of concurrent criteria, the Aldrete and Kroulik Scale was considered as the gold standard, and the analysis by means of the Spearman correlation. For validity of predictive criteria for complications, the Generalized Equations Estimating method was used. To verify the best cut-off point of the total score for discharge, the Receiver Operating Characteristic and Area Under the Curve curves were evaluated. Results: the apparent validation and the content obtained an overall average of 89% and the reliability analysis using the Intraclass Correlation Coefficient obtained an overall reliability of 0.91. As criterion validity, a comparison was made between the proposed scale and the gold standard, and there was a significant (p-value <0.001) and positive correlation, with "r" equal to or bigger than 0.5, for all parameters and between the total of each of the scales; except for the ventilation/respiration parameter (p-value = 0.397). Regarding the predictive criterion validity, the multivariate analysis strongly revealed the relationship of the parameters temperature, systolic blood pressure, peripheral oxygen saturation and mobility as the occurrence of complications. Through the Receiver Operating Characteristic curves and the Area Under the Curve, the cut-off points 39 (AUC = 0.667) and 38 (AUC = 0.594) are found, showing the best cut-off points. Conclusion: The Nursing Assessment Scale for the patient in the Post-Anesthetic Recovery Room is a reliable and valid instrument for the evaluation of the patient in the Post-Anesthetic Recovery Room.

Humans , Male , Female , Postoperative Complications , Perioperative Nursing , Surveys and Questionnaires , Postanesthesia Nursing , Validation Study , Pain , Anesthetics