Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 966
Filter
1.
Braz. j. biol ; 82: e233780, 2022. tab, graf
Article in English | LILACS | ID: biblio-1153469

ABSTRACT

Abstract Hematological and blood biochemical reference information is important to establish physiological status of freshwater stingray populations and improve care and management protocols in artificial environments. Here, we used a commercial freshwater stingray with high mortality rates in the market (Potamotrygon magdalenae), as an example to understand how artificial environments and handling protocols influence physiological status of captive freshwater stingrays. To this purpose, blood from five adult males and six adult females was collected to perform complete blood counts and blood chemistry analyses. All sampled animals showed good body condition with no differences between sexes. Differences between sexes were only found for the differential count of lymphocytes. Red blood results were consistent with previously studied potamotrygonids while white blood results showed higher values of leukocytes, thrombocytes, heterophils and lymphocytes in P. magdalenae compared to other Potamotrygonids. All types of leukocytes described for elasmobranchs were found except neutrophils and basophils. Blood metabolites showed an influence of ex situ diet in total protein, triglycerides and cholesterol. Glucose results were consistent while urea showed lower levels than those recorded for other freshwater stingrays. These results highlight the importance of physical, physiological and health analysis in freshwater stingrays as a part of welfare assessment to improve monitoring protocols and survival rates in public or private aquaria.


Resumo A informação de referência hematológica e bioquímica do sangue é importante para estabelecer o estado fisiológico das populações de arraias de água doce e melhorar os protocolos de cuidado e manejo em ambientes artificiais. Aqui, usamos uma espécie comercial de arraia de água doce com elevadas taxas de mortalidade no mercado (Potamotrygon magdalenae) como espécie exemplo para compreender de que modo os ambientes artificiais e os protocolos de manipulação influenciam o estado fisiológico das arraias de água doce em cativeiro. Para este fim, foi coletado sangue de cinco machos adultos e seis fêmeas adultas para realizar contagens completas de células sanguíneas e análises bioquímicas de sangue. Todos os animais amostrados mostraram boa condição corpórea, sem diferenças entre os sexos. Diferenças entre os sexos foram encontradas só na contagem diferencial de linfócitos. Os resultados de células sanguíneas vermelhas foram consistentes com potamotrigonídeos previamente estudados, enquanto o leucograma revelou valores mais elevados de leucócitos, trombócitos, heterófilos e linfócitos em P. magdalenae, em comparação com outros potamotrigonídeos. Todos os tipos de leucócitos descritos para elasmobrânquios foram encontrados, exceto para neutrófilos e basófilos. Todos os tipos de leucócitos descritos para elasmobrânquios foram encontrados, exceto para neutrófilos e basófilos. Os metabólitos do sangue mostraram influência da dieta ex situ nas proteínas totais, triglicerídeos e colesterol. Os resultados da glicose foram consistentes, enquanto a ureia mostrou níveis mais baixos do que os registrados para outras espécies de arraias de água doce. Os resultados da glicose foram consistentes, enquanto a ureia mostrou níveis mais baixos em P. magdalenae. Estes resultados enfatizam a importância da análise física, fisiológica e de saúde em arraias de água doce como parte da avaliação do bem-estar para melhorar os protocolos de monitoramento e as taxas de sobrevivência em aquários públicos ou privados.


Subject(s)
Animals , Male , Female , Skates, Fish , Elasmobranchii , Hematology , Fresh Water
3.
Rev. Bras. Cancerol. (Online) ; 68(1)jan./fev./mar. 2022.
Article in Portuguese | LILACS | ID: biblio-1370283

ABSTRACT

Introdução: Pacientes com câncer hematológico, candidatos a transplante de células-tronco hematopoiéticas (TCTH), requerem um autocuidado extenso, com tratamentos complexos e comportamentos de saúde adequados que são considerados fator-chave. Frente a essas complexidades, surge a importância do letramento em saúde. Objetivo: Descrever o nível de letramento e avaliar as inter-relações existentes entre letramento em saúde, estado nutricional, condições sociodemográficas e clínicas nos pacientes com câncer hematológicos e candidatos a TCTH em um hospital universitário terciário de Fortaleza-CE. Método: Estudo de caráter transversal realizado com 69 pacientes candidatos a TCHT, atendidos nesse hospital, que responderam à versão validada e traduzida do Newest Vital Sign (NVS-Br). Os dados clínicos e sociodemográficos foram coletados por meio da análise dos prontuários. O estado nutricional foi avaliado pelo índice de massa corporal (IMC), circunferência da cintura (CC) e CC associada à relação cintura-quadril (RCQ). Resultados: O letramento inadequado foi encontrado em 78,3% dos pacientes. Os fatores foram associados à idade (p=0,024), à baixa renda (p=0,005) e a menos anos de estudo (p=0,047). Conclusão: O estudo aponta para a necessidade de se melhorar o grau de letramento em saúde dos pacientes, a fim de obter melhores resultados no tratamento, principalmente naqueles que apresentam idade mais avançada, baixa renda e menor escolaridade


Introduction: Patients with hematologic cancer candidates for hematopoietic stem cell transplantation (HSCT) require extensive selfcare, with complex treatments and appropriate health behaviors that are considered a key factor. The importance of health literacy emerges because of these complexities. Objective: To describe the level of literacy and assess the interrelationships between health literacy, nutritional status, clinical and sociodemographic conditions in patients with hematologic cancer and candidates for HSCT in a tertiary university hospital in Fortaleza-CE. Method: Cross-sectional study conducted with 69 HSCT candidates, treated at a university hospital, who responded to the validated and translated version of the Newest Vital Sign (NVS-Br). Clinical and sociodemographic data were collected through the analysis of medical records. Nutritional status was assessed using body mass index (BMI), waist circumference (WC) and WC associated with hip circumference (WH). Results: Inadequate literacy was found in 78.3% of patients. Factors were associated with age (p=0.024), low income (p=0.005) and less years of education (p=0.047). Conclusion: The results indicated the necessity to improve the level of health literacy of patients for better treatment results, especially in older adults with low income and poor education level


Introducción: Los pacientes con cáncer hematológico candidatos a trasplante de células madre hematopoyéticas (TCMH) requieren un autocuidado extenso, con tratamientos complejos y conductas de salud adecuadas que se consideran un factor clave. Frente a estas complejidades, surge la importancia de la alfabetización en salud. Objetivo: Describir el nivel de alfabetización y evaluar las interrelaciones entre alfabetización en salud, estado nutricional, datos clínicos y condiciones sociodemográficas en pacientes con cáncer hematológico candidatos a TCMH en un hospital universitario terciario de Fortaleza-CE. Método: Estudio transversal realizado con 69 candidatos a TCMH, atendidos en este hospital, que respondieron a la versión validada y traducida del Newest Vital Sign (NVSBr). Los datos clínicos y datos sociodemográficos se recolectaron mediante el análisis de historias clínicas. El estado nutricional se evaluó mediante el indice de masa corporal (IMC), la circunferencia de la cintura (CC) y la CC asociada con la circunferencia de la cadera (CCR). Resultados: Se encontró alfabetización inadecuada en el 78,3% de los pacientes. Los factores se asociaron con la edad (p=0,024), bajos ingresos (p=0,005) y menos años de educación (p=0,047). Conclusión: Este estudio apunta a la necesidad de mejorar el nivel de alfabetización en salud de los pacientes con el fin de obtener mejores resultados de tratamiento, especialmente en aquellos que son mayores, tienen bajos ingresos y tienen menos educación


Subject(s)
Humans , Male , Female , Leukemia , Nutritional Status , Hematopoietic Stem Cell Transplantation , Health Literacy , Hematology
4.
Rev. bras. ciênc. vet ; 28(4): 211-217, out./dez. 2021. il.
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1363493

ABSTRACT

O objetivo do presente estudo foi validar intervalos de referências (IRs) para hematologia e bioquímica sanguínea de cães domiciliados da Amazônia Oriental e estabelecer novos IRs para os parâmetros não validados. Foram utilizadas amostras de 44 cães adultos clinicamente saudáveis de diferentes raças e sexos. Na validação, foi utilizada a metodologia proposta pelo Clinical and Laboratory Standards Institute (CLSI) e na determinação dos IRs dos parâmetros não validados foi utilizada a metodologia estatística proposta pela American Society for Clinical Veterinary Pathology (ASCPV). Os IRs foram determinados por meio do programa Excel com o suplemento Reference Value Advisor (versão 2.1). O software realiza os cálculos de acordo com as recomendações CLSI, conforme sugerido pelas diretrizes da ASCVP. Um total de 25 parâmetros (13 hematológicos e 12 bioquímicos) foram submetidos ao processo de validação. Desse total, seis (24%) parâmetros não foram validados (Hemoglobina, CHGM, eosinófilos, linfócitos, albumina e GGT) e para estes foram estabelecidos novos intervalos. Para a maioria dos parâmetros hematológicos e bioquímicos (76%), os IRs estabelecidos previamente na literatura ainda são válidos para utilização em cães criados na Amazônia Oriental. Para os parâmetros não validados, apenas para eosinófilos e linfócitos recomendamos que outros trabalhos, com um número maior de animais, sejam realizados para confirmar os nossos resultados ou estabelecer novos IRs. Os IRs estabelecidos para hemoglobina, CHGM, albumina e GGT podem ser utilizados em substituição aos intervalos antigos.


The aim of the present study was to validate reference intervals (RIs) for hematology and blood biochemistry of dogs domiciled in the Eastern Amazon and to establish new RIs for parameters not yet validated. Samples from 44 clinically healthy adult dogs of different breeds and sexes were used. The methodology proposed by the Clinical and Laboratory Standards Institute (CLSI) was used for validation, and the statistical methodology proposed by the American Society for Clinical Veterinary Pathology (ASCPV) was used to determine the RIs of the non-validated parameters. The IRs were determined using the Excel program with the Reference Value Advisor add-in (version 2.1). The software performs calculations according to CLSI recommendations as suggested by the ASCVP guidelines. A total of 25 parameters (13 hematological and 12 biochemical) were submitted to the validation process. Of this total, six (24%) parameters were not validated (Hemoglobin, CHGM, eosinophils, lymphocytes, albumin and GGT) and new intervals were established for these. For most hematological and biochemical parameters (76%), the RIs previously established in the literature are still valid for use in dogs raised in the Eastern Amazon. For non-validated parameters, just for eosinophils and lymphocytes, we recommend that other studies, with a larger number of animals, be carried out to confirm our results or establish new IRs. The established IRs for hemoglobin, CHGM, albumin and GGT can be used in place of the old ranges.


Subject(s)
Animals , Dogs , Reference Values , Dogs , Reference Parameters , Hematologic Tests/veterinary , Biochemistry , Amazonian Ecosystem , Hematology
6.
Hematol., Transfus. Cell Ther. (Impr.) ; 43(3): 324-331, July-Sept. 2021. tab, ilus
Article in English | LILACS | ID: biblio-1346253

ABSTRACT

Introduction and objective: Sickle cell anemia (SCA) is a genetic condition that alters the conformation of deoxygenated red blood cells, which results in their stiffening and the occurrence of vaso-occlusive crises, endothelium damage, organ dysfunction and systemic complications. Additionally, SCA limits the participation of individuals in physical and social activities. As we consider that physical exercise promotes the recovery of functional capacity and cardiorespiratory conditioning, we aim to verify the patterns of prescription, the effects and safety of exercise for individuals with SCA. Methodology: We systematically reviewed the published literature focusing on clinical trials that correlated physical exercise with SCA patients and cross-sectional studies that applied the stress test. The data research was based on the PRISMA recommendations and the following databases were used: Medline by PubMed, Cochrane, PEDro, Scielo. Results: Six studies which were based on the evaluation of 212 patients aged between 13 and 40 years, were selected from 122 identified studies. Those studies associated the individual effort tolerance improvement, its inflammatory profile adjustment and the absence of alteration in the autonomic nervous system activity to physical exercise or stress test. Conclusion: Low-to-moderate intensity physical exercise increased the SCA individual tolerance without causing vaso-occlusive crises, nor changes in the hemorheological and inflammatory profiles.


Subject(s)
Humans , Adolescent , Adult , Exercise , Anemia, Sickle Cell , Hematology , Inflammation
7.
Medicina (B.Aires) ; 81(4): 536-545, ago. 2021. graf
Article in English | LILACS | ID: biblio-1346504

ABSTRACT

Abstract Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in pa tients with a hematological disease in Argentina. A completely anonymous survey from the Argentine Society of Hematology was delivered to all the hematologists in Argentina; it started in April 2020. A cut-off to analyze the data was performed in December 2020 and, finally, 419 patients were reported and suitable for the analysis (average age: 58 years, 90% with malignant diseases). After the COVID-19 diagnosis, the 30-day OS for the whole population was 80.2%. From the entire group (419), 101 (24.1%) individuals required intensive care unit admission, where the 30-day OS was 46.6%. Among allogeneic stem cell transplant recipients, the 30-day OS was 70.3%. Factors associated with a low OS were two or more comorbidities, an active hematological disease and history of chemotherapy. In individuals with the three factors, the 30-day OS was 49.6% while the 30-day OS in those without those factors was 100%. Patients with hematological diseases have a higher mortality than the general population. This group represents a challenge and requires careful decision-making of the treatment in order not to compromise the chances of cure.


Resumen El presente estudio tuvo por objetivo primario conocer la mortalidad de pacientes con enfermedad hematológica que presentaron infección por COVID-19 en Argentina. Para ello se difundió una encuesta desde la Sociedad Argentina de Hematología (SAH) entre los hematológos para informar sobre los pacientes con enfermedades hematológicas y diagnóstico de infección por SARS- CoV-2, entre el 19/4/2020, y el 7/12/2020. Se incluyeron individuos de todas las edades con diagnóstico de enfermedad hematológica benigna o maligna e infección por SARS-CoV-2 confirmada por técnica de RT-PCR. Se analizaron 419 pacientes (mediana 58 años; 90% enfermedades malignas). La supervivencia al día 30 fue de 80.2%. La supervivencia fue menor en aquellos que requirieron internación (74.2%), cuidados intensivos (46.6%) y asistencia respiratoria mecánica (36.8%). Entre los trasplantados alogénicos la supervivencia fue 70.3%. Los factores vinculados a la supervivencia global fueron las comorbilidades, el estado de la enfermedad al momento de la infección y el antecedente de quimioterapia. Se pudo establecer un score en el que aquellos que tuvieron un puntaje de 4 alcanzaron una supervivencia del 49.6% al día 30, mientras que la de los pacientes con score 0 fue del 100% a 30 días. En comparación con la población general, los pacientes con enfermedades hematológicas presentan una mayor mortalidad vinculada al COVID-19, motivo por el cual es primordial definir pautas destinadas a disminuir la exposición de los mismos sin comprometer las posibilidades de beneficiarse del tratamiento de la enfermedad de base.


Subject(s)
Humans , Middle Aged , COVID-19 , Hematology , Argentina/epidemiology , COVID-19 Testing , SARS-CoV-2
8.
Rev. cuba. hematol. inmunol. hemoter ; 37(1): e1288, ene.-mar. 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1251715

ABSTRACT

El sistema inmune madura gradualmente durante la infancia y el nacimiento es un momento crucial para este proceso. El paso por el canal del parto es el primer estímulo que el sistema inmunitario percibe para comenzar así su maduración progresiva. El timo como órgano linfoide primario, es el primero en aparecer entre todos los órganos linfoides; en este órgano ocurre la ontogenia, diferenciación y maduración de los linfocitos T que migran a los órganos linfoides secundarios como linfocitos T inmunocompetentes. La producción de IgA por los linfocitos B es uno de los mecanismos esenciales de respuesta inmune de las mucosas a las que protege en su forma de IgA secretoria. En el Instituto de Hematología e Inmunología, se atendieron en consulta 62 pacientes pediátricos entre uno y cinco años de edad, con antecedentes de infecciones respiratorias agudas frecuentes, con dos o más episodios en un mes, a los que se les diagnosticó por ultrasonografía una disminución del área tímica (hipoplasia). De ellos, 50 por ciento presentó además disminución de la concentración de IgA en suero. Estos resultados sugieren múltiples interrogantes. Consecuentemente, este trabajo tiene como objetivo presentar la asociación hallada entre la disminución del tamaño del timo y la disminución de la concentración en suero de IgA, en un grupo de niños de uno a cinco años, con antecedentes de infecciones respiratorias frecuentes, consultados en el Instituto de Hematología e Inmunología durante un año(AU)


The immune system gradually matures during childhood, and birth is a crucial moment in this process. Transit through the birth canal is the first stimulus perceived by the immune system to start its progressive maturation. The thymus, a primary lymphoid organ as it is, is the first lymphoid organ to appear. It is the site of the ontogeny, differentiation and maturation of the T-lymphocytes migrating to secondary lymphoid organs as immunocompetent T-lymphocytes. IgA production by B-lymphocytes is one of the essential immune response actions performed by mucosas, which they protect in the form of secretory IgA. A study was conducted of 62 pediatric patients aged 1-5 years attending consultation at the Institute of Hematology and Immunology who had a history of frequent acute respiratory infection, with two or more episodes in one month. These patients were ultrasonographically diagnosed with thymus size reduction (hypoplasia). Among them, 50 percent also presented a decrease in serum IgA concentration. These results pose many questions concerning the association between thymus hypoplasia and IgA reduction. The purpose of the study was therefore to present the association found between thymus size reduction and serum IgA concentration decrease in a group of children aged 1-5 years with a history of frequent respiratory infection attending the Institute of Hematology and Immunology during one year(AU)


Subject(s)
Humans , Respiratory Tract Infections , Thymus Gland , Immunoglobulin A, Secretory , Hematology
9.
Neotrop. ichthyol ; 19(1): e200136, 2021. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-1287439

ABSTRACT

Pygocentrus nattereri is a carnivorous fish widely distributed in the Brazilian wetland and occupies different river strata. Based on the sexual maturity, the standard length (SL) has been used to categorize age and physiological attributes. However, hematological parameters and their relationship with age and growth features are unknow. Here, the aim was to evaluate the hematological profile and leukocyte data of juvenile and adult specimens, associating it with SL. Specimens of both sexes were weighted, and SL were measured for classify as juveniles (SL ≤16.0 cm) and adults (SL ≥16.1 cm). Blood was collected to perform the hemogram, for leukocyte quantification and ultrastructural descriptions. In general, hemogram values and leukocyte, lymphocyte, and monocyte counts were high in juveniles. Hemogram variables were negatively correlated with SL. Thrombocyte and neutrophil counts were higher in adults than in juveniles. SL was correlated with leukogram variables. Ultrastructural analysis showed that granular leukocyte count in P. nattereri was similar another fishes. PAS-positive granular leukocytes are slightly smaller than neutrophils and are characterized by dense elongated and semi-lunar shapes in the cytoplasm. Our results suggest that age-based SL may be useful for the analysis of the relationship between P. nattereri health status and wetland aquatic environments.(AU)


Pygocentrus nattereri é um peixe carnívoro amplamente distribuído no pantanal brasileiro e ocupa diferentes estratos de rios. Com base na maturidade sexual, o comprimento padrão (CP) tem sido usado para categorizar a idade e os atributos fisiológicos. No entanto, os parâmetros hematológicos e sua relação com a idade e características de crescimento são desconhecidos. O objetivo foi avaliar o perfil hematológico e leucocitário de espécimes juvenis e adultos, associando-o ao CP. Espécimes de ambos os sexos foram pesados e os CPs foram medidos para classificação em juvenis (CP ≤16,0 cm) e adultos (CP ≥16,1 cm). Foi coletado sangue para realização do hemograma, perfil e morfologia dos leucócitos. Em geral, os valores do hemograma e as contagens de leucócitos, linfócitos e monócitos foram maiores nos jovens. A contagem de trombócitos e neutrófilos foi maior em adultos do que em jovens. A análise ultraestrutural mostrou que a contagem de leucócitos granulares em P. nattereri foi semelhante a outros peixes. Os leucócitos granulares PAS-positivos são menores do que os neutrófilos, sendo caracterizados por formas alongadas e semilunares densas no citoplasma. Nossos resultados sugerem que CP é útil para a análise da relação entre o estado de saúde de P. nattereri em ambientes aquáticos alagados.(AU)


Subject(s)
Animals , Blood Platelets , Reference Parameters , Characiformes/blood , Fishes , Leukocyte Count , Hematology
10.
Braz. arch. biol. technol ; 64: e21200187, 2021. tab, graf
Article in English | LILACS | ID: biblio-1249205

ABSTRACT

Abstract Plant based protein sources are one of the best, cost effective and easily available protein sources being used in fish feed. But due to a lower number of micro-biota in fish gut plant meal based diets cannot be digested and absorbed well in fish body. Probiotics were supplemented at 0, 1, 2, 3, 4 and 5 gkg-1 levels in fish feed for formulating one control and five test diets. In this study, three replicates of each treatment were used and number of fingerlings was 15 in each replicate. The C. carpio (common carp) fingerlings were fed at 5% of live wet weight on their prescribed diet twice daily. The results revealed that supplementation of probiotics in corn gluten meal based diets significantly (p<0.05) improved growth performance, carcass composition and hematological parameters. Most optimum values of growth performance parameters were noted at 2 gkg-1 level of probiotics supplemented diet. C. carpio fingerlings fed corn gluten meal based diet supplemented with 2 gkg-1 level of probiotics indicated significant (p<0.05) improvements in crude protein (17g) crude fat (9g) and gross energy (3 kcalg-1) whereas higher red blood cells (RBCs), white blood cells (WBCs) and hemoglobin (Hb) was also recorded in fish blood when fed 2 gkg-1 probiotics level diet. From these results, it was concluded that 2 gkg-1 probiotics supplementation in corn gluten meal based diet is optimum for improving growth performance, body composition and hematology of C. carpio fingerlings.


Subject(s)
Body Composition/physiology , Carps , Probiotics/administration & dosage , Hematology , Zea mays
11.
Rev. méd. Minas Gerais ; 31: 31416, 2021.
Article in Portuguese | LILACS | ID: biblio-1354551

ABSTRACT

O presente relato de caso descreve a apresentação atípica de uma paciente com adenocarcinoma endometrioide invasivo que evoluiu com aplasia pura adquirida crônica da série vermelha secundária à quimioterapia. Paciente de 71 anos, sexo feminino, procurou atendimento médico por quadro de metrorragia com três meses de evolução. A curetagem uterina evidenciou adenocarcinoma endometrioide invasor moderadamente diferenciado. Iniciou-se uma abordagem com esquema quimioterápico composto por Carboplatina e Paclitaxel interrompido ao quinto ciclo para evitar progressão de aplasia medular constatada por biópsia de medula óssea. A possível hematotoxicidade do protocolo Paclitaxel e Carboplatina foi observada na conduta terapêutica da paciente, por sua progressão para uma apresentação atípica de aplasia pura adquirida crônica da série vermelha após administração desta associação de drogas.


The present case report describes the atypical presentation of a patient with invasive endometrioid adenocarcinoma that evolved with chronic acquired pure aplasia of the red series secondary to chemotherapy. A seventy-one-yearold patient, female, sought medical care for a three-month-old metrorrhagia evolution. The uterine curettage showed moderately differentiated invasive endometrioid adenocarcinoma. It was initiated an approach with chemotherapy regimen consisting of Carboplatin and Paclitaxel interrupted at the fifth cycle to prevent progression of spinal aplasia found by bone marrow biopsy. The possible hematoxicity of the patient, for its progression to an atypical presentation of chronic acquired aplasia of the red series after administration of this combination of drugs.


Subject(s)
Female , Aged , Red-Cell Aplasia, Pure , Carcinoma, Endometrioid , Bone Marrow , Drug Therapy , Hematology , Antineoplastic Agents
12.
Ciênc. cuid. saúde ; 20: e58988, 2021.
Article in Portuguese | LILACS, BDENF | ID: biblio-1356105

ABSTRACT

RESUMO Objetivo: Compreender o imaginário do Reiki integrado ao cuidado de Enfermagem no quotidiano de pessoas e de famílias em vivência do câncer. Metodologia: Pesquisa Convergente Assistencial fundamentada na Sociologia Compreensiva e do Quotidiano, realizada com 20 participantes em uma clínica de tratamento oncológico e hematológico no sul do Brasil, de julho a dezembro de 2018. Aprovação pelo Comitê de Ética e Pesquisa, n.º 2.765.976; realizaram-se de três a cinco sessões de Reiki, e após cada sessão, entrevista aberta individual com roteiro semiestruturado. Adotou-se o Processo de Cuidar em Enfermagem considerando o Quotidiano e o Imaginário em Saúde. A Análise dos dados seguiu a propostada Análise Temática. Resultados: O Imaginário sobre o Reiki, integrado ao cuidado de Enfermagem no quotidiano de pessoas e de famílias que vivenciam o câncer, delineia a experiência com o Reiki e os seus significados, apontando os benefícios de sentir-se bem, atenuação ou desaparecimento das dores; equilíbrios energético, emocional, espiritual e físico. Considerações Finais: O imaginário sobre o Reiki mostrou uma experiência que permitiu vivenciar a desmistificação da doença, a atitude positiva - enquanto potência para seu enfrentamento, possibilitou emergir a força vital de cada pessoa e família, promovendo a saúde no viver e conviver, a partir da razão sensível.


RESUMEN Objetivo: comprender el imaginario del Reiki integrado al cuidado de Enfermería en el cotidiano de personas y familias en vivencia del cáncer. Metodología: investigación Convergente Asistencial fundamentada en la Sociología Comprensiva y del Cotidiano, realizada con 20 participantes en una clínica de tratamiento oncológico y hematológico en el sur de Brasil, de julio a diciembre de 2018. Aprobación por el Comité de Ética e Investigación, n.º 2.765.976; se realizaron de tres a cinco sesiones de Reiki, y después de cada sesión, entrevista abierta individual con guion semiestructurado. Se adoptó el Proceso de Cuidar en Enfermería considerando el Cotidiano y el Imaginario en Salud. El análisis de los datos siguió la propuesta del Análisis Temático. Resultados: el Imaginario sobre el Reiki, integrado al cuidado de Enfermería en el cotidiano de personas y familias que viven el cáncer, delinea la experiencia con el Reiki y sus significados, señalando los beneficios de sentirse bien, atenuación o desaparición de los dolores; equilibrio energético, emocional, espiritual y físico. Consideraciones finales: el imaginario sobre el Reiki mostró una experiencia que permitió experimentar la desmitificación de la enfermedad, la actitud positiva - como potencia para su enfrentamiento -, posibilitó surgir la fuerza vital de cada persona y familia, promoviendo la salud en el vivir y convivir, a partir de la razón sensible.


ABSTRACT Objective: To understand the imagery of Reiki integrated into Nursing care in the daily lives of people and families living with cancer. Methodology: Convergent Care Research based on Comprehensive and Everyday Sociology, carried out with 20 participants in an oncological and hematological treatment clinic in southern Brazil, from July to December 2018. Approval by the Research Ethics Committee number 2.765.976; three to five Reiki sessions were held and after each session, there were individual open interviews with a semi-structured script. The Nursing Care Process was adopted, considering the Daily and the Imaginary in Health. Data analysis followed the proposal of Thematic Analysis. Results: the imagery about Reiki, integrated into nursing care in the daily lives of people and families who experience cancer, outlines the experience with Reiki and its meanings, pointing out the benefits of feeling good, having improved attenuation and disappearance of pains; energetic, emotional, spiritual and physical balances. Final Considerations: The imagery about Reiki showed an experience that allowed experiencing the demystification of the disease, a positive attitude, as a power to face it; it enabled to emerge the vital force of each person and family, promoting health in living, based on sensitive reason.


Subject(s)
Humans , Male , Female , Family , Nursing , Therapeutic Touch , Empathy , Neoplasms , Pain , Complementary Therapies , Activities of Daily Living , Disease , Drug Therapy , Emotions , Optimism , Hematology , Medical Oncology
13.
Ciênc. Saúde Colet ; 25(12): 4969-4978, Dec. 2020. tab
Article in English, Portuguese | ColecionaSUS, LILACS, ColecionaSUS, SES-SP | ID: biblio-1142700

ABSTRACT

Resumo O artigo tem por objetivo discutir as consequências das medidas de distanciamento social sobre a disponibilidade de sangue e a organização dos serviços hemoterápicos no início da pandemia de Covid-19 no Brasil. A partir do acesso às notícias publicadas no mês de abril de 2020 nos sites das Hemorredes estaduais do país e organizadas em matriz Excel, foram elaborados quadros-síntese e descrição de resultados. A situação crítica de abastecimento de sangue, em especial para alguns tipos sanguíneos, foi constatada em muitos estados, devido à circulação do novo coronavírus. A adoção de medidas de distanciamento social e a manutenção das demandas por transfusão para tratamentos, urgência e emergência, requereram a implantação e a implementação de estratégias e ações para reorganização dos serviços. Medidas de proteção foram incorporadas, fluxos alterados e rotinas estabelecidas. Este estudo evidencia o quanto a situação epidemiológica da Covid-19 e as medidas necessárias para o seu controle influenciaram sobre a situação dos estoques e disponibilidade de sangue, e, demandaram, mudanças na organização dos serviços hemoterápicos a fim de assegurar a proteção, mitigar os riscos de propagação do vírus e garantir o suprimento de sangue para o atendimento às necessidades do sistema de saúde.


Abstract The article aims to discuss the consequences of social distancing measures on the availability of blood and organization of blood therapy services at the beginning of the Covid-19 pandemic in Brazil. News published in April 2020 on the websites of the country's state Blood Service Networks were consulted and organized in an Excel spreadsheet, presented in summary charts, and descriptions of results were prepared. A critical situation of blood supply, especially of some blood types, has been observed in many states. This situation is influenced by the circulation of the new coronavirus. The adoption of social distancing measures associated with unchanged transfusion demands for outpatient, urgency and emergency care required the implementation of strategies and actions for the reorganization of the services. Protection measures were incorporated, flows were changed and new routines were established. This study shows the extent to which the epidemiological situation of Covid-19 and the necessary measures for its control influenced the stocks and availability of blood. Changes in the organization of blood therapy services were fundamental in order to ensure protection, mitigate the risks of spreading the virus, and ensure the blood supply to meet the needs of the health system.


Subject(s)
Personal Space , Blood Banks/organization & administration , Coronavirus Infections/epidemiology , Pandemics , Betacoronavirus , Hematology/organization & administration , Blood Banks/supply & distribution , Blood Donors/supply & distribution , Brazil/epidemiology , Internet
14.
Rev. MVZ Córdoba ; 25(3): 17-24, sep.-dic. 2020. tab
Article in Spanish | LILACS | ID: biblio-1347062

ABSTRACT

RESUMEN Objetivo. Determinar los parámetros hematológicos según el estado reproductivo en caballos peruanos de Paso en la provincia de Lambayeque. Materiales y métodos. Se realizó la investigación con 60 caballos adultos (>4 años), clínicamente sanos y sin tratamiento farmacológico previo; según su estado reproductivo se formaron cuatro grupos de 15 ejemplares cada uno: macho castrado, macho entero, yegua vacía y yegua gestante. Primero se realizó el examen clínico general para confirmar su buen estado de salud, luego se extrajo sangre de la vena yugular a todos los caballos. Las muestras se procesaron por análisis hematológicos y se determinaron las variables de la serie roja (hemoglobina, hematocrito, glóbulos rojos, volumen corpuscular medio [VCM], hemoglobina corpuscular media [HCM] y concentración de hemoglobina corpuscular media [CHCM]). Igualmente, la serie blanca (leucocitos, neutrófilos segmentados y abastonados, basófilos, monocitos, linfocitos, eosinófilos) y serie trombocítica fueron procesados y determinados. Se utilizaron métodos manuales, fórmulas matemáticas y método Drabkin en el laboratorio de patología clínica. Se aplicó la prueba estadística de Kruskal Wallis y se obtuvo la media, desviación estándar y rangos de las variables. Resultados. No se encontraron diferencias estadísticamente significativas en la serie blanca, roja y trombocítica de acuerdo con el sexo o estado reproductivo, a excepción del número de los basófilos que fue mayor en machos enteros. Conclusiones. Los parámetros hematológicos según el estado reproductivo del caballo peruano de paso se encuentran dentro de los rangos establecidos por la literatura especializada. Sin embargo, el número los linfocitos que fue mucho menor.


ABSTRACT Objective. To determine the haematological parameters according to the reproductive status of Peruvian Paso horses in the Province of Lambayeque. Materials and methods. The research was conducted on 60 clinically healthy adult horses (> 4 years), without previous drug treatment. Four groups of 15 horses were formed: gelding, entire male, empty mare and pregnant mare. First, a general clinical examination was performed to confirm their good health. Blood was drawn from the jugular vein of all the horses. The samples were processed by haematological analysis and the parameters of the red series (haemoglobin, haematocrit, red blood cells, mean corpuscular volume [MCV], mean corpuscular haemoglobin [MCH] and the mean corpuscular haemoglobin concentration [MCHC] were determined. Likewise, the white series (leukocytes, neutrophils segmented and stacked, basophils, monocytes, lymphocytes, eosinophils) and the thrombocytic series were processed and the unit range determined. Manual methods, mathematical formulas and the Drabkin method were used in the clinical pathology laboratory. The Kruskal Wallis Statistical test was applied and consequently the mean, standard deviation and ranges of variables were obtained. Results. No significant statistical differences were found in the white, red and thrombocytic series according to sex or reproductive status, except the number of basophils was higher in the entire males. Conclusions. The haematological parameters according to the reproductive status of the Peruvian Step horse are within the normal ranges (as per the literature pertaining to this area). However, the number of lymphocytes was much lower.


Subject(s)
Animals , Reproduction , Hematology , Horses
15.
Rev. cuba. hematol. inmunol. hemoter ; 36(4): e1175, oct.-dic. 2020. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289420

ABSTRACT

La trombosis se puede definir como un trastorno vascular que se presenta cuando se desarrolla un trombo que bloquea de forma total o parcial el interior de un vaso sanguíneo, ya sea una vena o una arteria. La trombofilia define a una alteración de la hemostasia que predispone al desarrollo de trombosis; sin embargo, la presencia de una trombofilia no implica necesariamente la aparición de un evento trombótico. La deficiencia de los inhibidores fisiológicos, como las proteínas C y S, constituyen factores de riesgo hereditarios y adquiridos que favorecen al desarrollo de trombosis. Se determinó la incidencia de deficiencia de estas proteínas de la coagulación en pacientes con historia obstétrica adversa, eventos de trombosis y otros eventos asociados. Se realizó un estudio longitudinal prospectivo en el período comprendido del 2011 al 2018, en un grupo de pacientes remitidos al Instituto de Hematología e Inmunología, a los que se les realizó la medición de los niveles plasmáticos de las proteínas C y S. En 133 pacientes (52,17 por ciento) se detectó deficiencia de proteína C (n=50), proteína S (n=66) o ambas (n=17). Las principales causas de realización de estos estudios fueron la historia obstétrica adversa y los eventos trombóticos y coincidieron con los eventos clínicos donde predominó alguna deficiencia. La deficiencia de proteína S tuvo mayor incidencia(AU)


Thrombosis is a vascular disorder appearing when a thrombus totally or partially blocks the inside of a blood vessel, be it a vein or an artery. Thrombophilia is a hemostatic alteration leading to thrombosis. However, the presence of thrombophilia does not necessarily imply the appearance of a thrombotic event. Deficiency in physiological inhibitors such as proteins C and S is a hereditary or acquired risk factor fostering thrombosis. Determination was made of the incidence of deficiency in these coagulation proteins in patients with an adverse obstetric history, thrombotic events and other associated disorders. A prospective longitudinal study was conducted in the period 2011-2018 of a group of patients referred to the Institute of Hematology and Immunology, who underwent measurement of their plasma levels of proteins C and S. A total 133 patients (52.17 percent) were found to be deficient in protein C (n=50), protein S (n=66) or both (n=17). The main reasons for the conduct of these studies were an adverse obstetric history and thrombotic events, which coincided with clinical disorders in which some sort of deficiency prevailed. Protein S deficiency was the most common(AU)


Subject(s)
Humans , Thrombosis , Protein S Deficiency , Protein C Deficiency , Hematology , Prospective Studies , Longitudinal Studies
16.
Anon.
Rev. cuba. hematol. inmunol. hemoter ; 36(4): e1380, oct.-dic. 2020.
Article in Spanish | LILACS, CUMED | ID: biblio-1289424

Subject(s)
Humans , Periodical , Hematology , Review
17.
Rev. bras. anal. clin ; 52(4): 376-382, 20201230. tab
Article in Portuguese | LILACS | ID: biblio-1248338

ABSTRACT

Objetivo: Avaliar o desempenho do equipamento Mindray® BC-5380 através da métrica sigma. Métodos: Os parâmetros incluídos neste estudo são leucócitos, eritrócitos, hemoglobina, hematócrito, volume corpuscular médio, hemoglobina corpuscular média, concentração de hemoglobina corpuscular média, amplitude de distribuição dos eritrócitos e plaquetas. Os cálculos foram realizados a partir de dados provenientes da rotina de controle de qualidade do laboratório, determinando-se a inexatidão, imprecisão, o erro total analítico e a métrica sigma dos parâmetros. Resultados: Valores aceitáveis de Sigma (>3) calculados com base nas especificações da qualidade CLIA foram encontrados para todos os parâmetros, exceto hematócrito. Calculando-se a métrica com base em especificações de variação biológica, hematócrito, volume corpuscular médio e hemoglobina corpuscular média apresentam desempenho inaceitável em pelo menos algum nível de controle, e a concentração de hemoglobina corpuscular média apresenta resultado inaceitável em todos os níveis. A contagem de leucócitos totais foi o único parâmetro com desempenho excelente em todos os níveis de controle, perante todas as especificações de qualidade aplicadas. Conclusão: A utilização da métrica sigma na avaliação do desempenho analítico permite identificar falhas não detectadas pelo controle de qualidade convencional, sendo um importante recurso para a melhoria contínua da qualidade.


Objective: To evaluate the performance of the Mindray® BC-5380 equipment using the sigma metric. Methods: The parameters included in this study are leukocytes, erythrocytes, hemoglobin, hematocrit, average corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width and platelets. The calculations were performed based on data from the laboratory's quality control routine, determining inaccuracy, imprecision, total analytical error and the sigma metric of the parameters. Results: Acceptable values of Sigma (> 3) calculated based on CLIA specifications were found for all parameters, except hematocrit Calculating the metric based on specifications of biological variation, hematocrit, mean corpuscular volume and mean corpuscular hemoglobin present unacceptable performance in at least one level of control, and the mean corpuscular hemoglobin concentration shows unacceptable results at all levels. The total leukocyte count was the only parameter with excellent performance at all levels of control, with the quality specifications applied. Conclusion: The use of the sigma metric in the evaluation of analytical performance allows to identify flaws not detected by conventional quality control, being an important resource for continuous quality improvement.


Subject(s)
Quality Control , Analytical Quality Control , Total Quality Management , Hematology
18.
Rev. bras. anal. clin ; 52(4): 310-317, 20201230. tab
Article in Portuguese | LILACS | ID: biblio-1223472

ABSTRACT

Introdução: O benzeno é um composto proveniente do petróleo, adicionado à gasolina em pequena quantidade para aumentar a octanagem desse combustível. Esse composto está presente nos veículos, por isso a população está exposta à emissão de vapores de gasolina. Contudo, deve-se ter uma atenção especial aos trabalhadores de postos de gasolina, pois esses são submetidos a níveis altos de benzeno, que pode causar desde sintomas por exposição aguda até o desenvolvimento de leucemia pela cronicidade da exposição. Objetivo: Estudar as alterações biológicas pela exposição ao benzeno em operadores de postos de serviços e bombas de abastecimento inflamáveis, analisar os riscos do hidrocarboneto benzeno ao organismo destes trabalhadores e propor a inserção de análise de um novo perfil hematológico, bioquímico e imunológico no exame médico ocupacional destes trabalhadores. Material e Método: Este trabalho consiste em uma revisão sistemática qualitativa da literatura, fundamentada nas recomendações do PRISMA statement, utilizando-se como frase de busca: ("Hidrocarbon*" OR "Benzen") AND ("hematology*") AND ("filling station"). Resultado: Os achados de seis artigos originais foram apresentados em tabela. Conclusões: Estudos complementares devem ser realizados com a finalidade de detectar marcadores que permitam o diagnóstico precoce dos danos hematológicos, bioquímicos e imunológicos provocados pela exposição ao benzeno.


Introduction: Benzene is a petroleum compound, that is added to gasoline in small quantities to increase the octane of this fuel. This compound is present in vehicles, so the population as a whole is exposed to the emission of gasoline vapors. However, special attention should be paid to gas station workers, because they are subjected to high levels of benzene, which can cause from acute exposure symptoms to the development of leukemia due to chronic exposure. Objective: To study the biological changes due to benzene exposure in service station and flammable supply pumps operators, to analyze the risks of benzene to the organism of these workers and to propose the insertion of a new hematological, biochemical and immunological profile in the medical examination occupational of workers. Material and Method: This work consists of a qualitative systematic literature review, based on the recommendations of the PRISMA statement, using as search phrase: ("Hydrocarbon *" OR "Benzen") AND ("hematology *") AND ("filling station"). Results: The findings of six original articles were presented in a table. Conclusions: Complementary studies should be performed to detect markers, that allow the early diagnosis of hematological, biochemical and immunological damage, caused by exposure to benzene.


Subject(s)
Benzene , Occupational Exposure , Filling Station , Hematology
19.
Bol. méd. postgrado ; 36(2): 21-25, dic.2020. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1117893

ABSTRACT

El síndrome de lisis tumoral (SLT) es una complicación potencialmente letal provocada por la liberación masiva de ácidos nucleicos, potasio y fosfato hacia la circulación sistémica lo cual se asocia a graves trastornos del metabolismo hidroelectrolítico. Se realizó una revisión retrospectiva de historias clínicas con el objetivo de describir las características clínicas de los pacientes con sospecha de SLT que ingresaron al Servicio de Medicina Interna del Hospital General Universitario Dr. Luis Gómez López durante el lapso 2017-2018. El 50% de los pacientes tenían una edad comprendida entre 51 y 70 años, siendo el 65% de sexo femenino. Los canceres más frecuentemente encontrados fueron el cáncer de mama (29%), cáncer gástrico (15%) y el linfoma no Hodgkin (12%). Todos los pacientes presentaron al menos tres de las manifestaciones clínicas asociadas al SLT entre las cuales se encuentran náuseas, vómitos, anorexia, debilidad, calambres, hiperreflexia, oliguria, anuria, hematuria, hipotensión, convulsiones y deshidratación. El 46% de los pacientes presentaron hiperpotasemia, mientras que 36% mostraron hipocalcemia y 18% hiperfosfatemia. El 76% de los pacientes cursaron con una creatinina > 1,4 mg/dl. El diagnóstico definitivo de SLT no fue posible realizarlo en ninguno de los pacientes incluidos en este estudio debido a la falta de estudios paraclínicos necesarios para satisfacer los criterios según los lineamientos internacionales(AU)


Tumor lysis syndrome (TLS) is a potentially lethal complication due to massive release of nucleic acids, potassium and phosphate into the systemic circulation which is associated with severe hydroelectrolitic metabolic disorders. A retrospective review of clinical charts was performed in order to describe clinical characteristics of patients with possible TLS that were admitted to the Servicio de Medicina Interna of the Hospital General Universitario Dr. Luis Gómez López during the period 2017-2018. The results show that 50% of patients were between 51 and 70 years old and 65% were female. Breast cancer (29%), stomach cancer (15%) and Non-Hodgkin lymphoma (12%) were more frequent in patients with possible TLS. All patients showed at least three of the clinical features commonly associated with TLS such as nausea, vomiting, anorexia, weakness, cramps, hyperreflexia, oliguria, anuria, hematuria, hypotension, convulsion and dehydration. 46% of patients had hyperkalemia, 36% hypocalcemia and 18% hyperphosphatemia. Creatinine levels > 1,4 mg/dl were seen in 76% of patients. Definitive diagnosis of TLS was not possible in any of the patients included in this study due to the lack of laboratory studies required according to international guidelines(AU)


Subject(s)
Humans , Phosphates , Potassium , Radiotherapy , Breast Neoplasms , Nucleic Acids , Tumor Lysis Syndrome/physiopathology , Drug Therapy , Drug Prescriptions , Critical Care , Hematology , Internal Medicine , Medical Oncology
20.
Hematol., Transfus. Cell Ther. (Impr.) ; 42(4): 293-299, Oct.-Dec. 2020. tab, graf
Article in English | LILACS | ID: biblio-1142962

ABSTRACT

ABSTRACT During the COVID-19 pandemic, special attention has been addressed in cancer care to mitigate the impact on the patient's prognosis. We addressed our preparation to face COVID-19 pandemic in a Hematological and Stem Cell Transplant Unit in Brazil during the first two months of COVID-19 pandemic and described COVID-19 cases in patients and health care workers (HCW). Modifications in daily routines included a separation of area and professionals, SARS-CoV-2 screening protocols, and others. A total of 47 patients and 54 HCW were tested for COVID-19, by PCR-SARS-CoV-2. We report 11 cases of COVID-19 in hematological patients (including 2 post stem cell transplant) and 28 cases in HCW. Hematological cases were most severe or moderate and presented with several poor risk factors. Among HCW, COVID-19 were mostly mild, and all recovered without hospitalization. A cluster was observed among HCW. Despite a decrease in the number of procedures, the Transplant Program performed 8 autologous and 4 allogeneic SCT during the period, and 49 onco-hematological patients were admitted to continuing their treatments. Although we observed a high frequency of COVID-19 among patients and HCW, showing that SARS-CoV-2 is disseminated in Brazil, hematological patients were safely treated during pandemic times.


Subject(s)
Humans , Infectious Disease Transmission, Professional-to-Patient , Medical Care , Stem Cell Transplantation , Pandemics , Patient Care Bundles , SARS-CoV-2 , COVID-19 , Neoplasms , Delivery of Health Care , Hematology
SELECTION OF CITATIONS
SEARCH DETAIL