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1.
Arq. bras. cardiol ; 118(3): 548-555, mar. 2022. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1364352

ABSTRACT

Resumo Fundamento É importante saber qual medicamento usar como tratamento de primeira linha para fechar o duto. Objetivos O objetivo deste estudo é comparar a eficácia e os efeitos colaterais das formas intravenosas (IV) de ibuprofeno e paracetamol e contribuir para a literatura investigando o primeiro medicamento selecionado no tratamento clínico da persistência do canal arterial (PCA). Métodos Nosso estudo foi realizado entre janeiro de 2017 e dezembro de 2019. Foram incluídos no estudo bebês prematuros com peso ao nascer (PN) ≤1500 g e idade gestacional (IG) ≤32 semanas. No período do estudo, todos os bebês com persistência do canal arterial hemodinamicamente significativa (hsPCA) receberam ibuprofeno intravenoso (IV) como resgate como tratamento clínico primário ou tratamento com paracetamol IV se houvesse contraindicações para o ibuprofeno. Os pacientes foram divididos em dois grupos: pacientes que receberam ibuprofeno IV e pacientes que receberam paracetamol IV. Resultados Desses pacientes, 101 receberam paracetamol IV e 169 receberam ibuprofeno IV. A taxa de sucesso do fechamento da PCA com o primeiro curso do tratamento foi de 74,3% no grupo de paracetamol IV e 72,8% no grupo de ibuprofeno IV (p=0,212). Conclusões Nossos resultados mostram que o paracetamol IV é tão eficaz quanto o ibuprofeno IV no tratamento de primeira linha de hsPCA, podendo se tornar o tratamento preferencial para o controle de hsPCA.


Abstract Background It is important which medicine to use as a first-line treatment to close the duct. Objectives The aim of this study is to compare the effectiveness and side effects of intravenous (IV) forms of ibuprofen and paracetamol and to contribute to the literature investigating the first drug selected in the medical treatment of patent ductus arteriosus (PDA). Methods Our study was conducted between January 2017 and December 2019. Premature infants with birth weight (BW) ≤1500 g and gestational age (GA) ≤32 weeks were included in the study. In the study period, all infants with hemodynamically significant patent ductus arteriosus (hsPDA) were given rescue intravenous (IV) ibuprofen as a primary medical treatment or IV paracetamol treatment if there were contraindications for ibuprofen. The patients were divided into two groups: patients receiving IV ibuprofen and patients receiving IV paracetamol. Results Of these patients, 101 were given IV paracetamol and 169 were given IV ibuprofen. The success rate of PDA closure with first-course treatment was 74.3% in the IV paracetamol group and 72.8% in the IV ibuprofen group (p=0.212). Conclusions Our results show that IV paracetamol is as effective as IV ibuprofen in the first-line treatment of hsPDA, and can become the preferred treatment for the management of hsPDA.


Subject(s)
Humans , Infant, Newborn , Infant , Ductus Arteriosus, Patent/drug therapy , Infant, Low Birth Weight , Infant, Premature , Ibuprofen/adverse effects , Ibuprofen/therapeutic use , Acetaminophen/adverse effects , Acetaminophen/therapeutic use
2.
Cad. Saúde Pública (Online) ; 38(2): e00316920, 2022. tab, graf
Article in Portuguese | LILACS | ID: biblio-1360286

ABSTRACT

Resumo: O objetivo deste artigo foi avaliar os fatores socioeconômicos, familiares e individuais associados ao desenvolvimento infantil no primeiro ano de vida, entre famílias em vulnerabilidade social. Trata-se de uma análise transversal, com dados da linha de base de um ensaio randomizado. O estudo incluiu 3.242 crianças < 12 meses de idade, residentes em 30 municípios de cinco regiões do Brasil. A escolha de estados e municípios foi intencional, tendo como base a implementação do Programa Criança Feliz. A amostra foi selecionada a partir de crianças elegíveis para o Programa Criança Feliz, cujo objetivo é promover a estimulação e o desenvolvimento infantil. O Ages and Stages Questionnaire (ASQ) foi utilizado para avaliação do desenvolvimento infantil. Um modelo de análise multinível em três níveis (estado, município e indivíduos), usando teste de Wald para heterogeneidade e tendência linear, estimou a média do ASQ-3 e intervalo de 95% de confiança (IC95%). Análises foram ajustadas para potenciais confundidores. Foram analisadas informações de 3.061 (94,4%) crianças com dados disponíveis para ASQ-3. Escores de desenvolvimento infantil (total e em todos os domínios) foram cerca de 12% menores em crianças nascidas pré-termo e com restrição do crescimento intrauterino (pequenas para idade gestacional). Observou-se menores escores em filhos de mães com baixa escolaridade, com sintomas de depressão, com duas ou mais crianças menores de sete anos residindo no domicílio e que não relataram autopercepção de apoio/ajuda durante a gestação. Conclui-se que características potencialmente modificáveis (escolaridade, depressão materna e prematuridade/restrição do crescimento intrauterino) apresentaram maior impacto na redução do escore de desenvolvimento em todos os domínios avaliados.


Abstract: The study aimed to assess socioeconomic, family, and individual factors associated with infant development (i.e., in the first year of life) among families with social vulnerability. This was a cross-sectional analysis of baseline data from a randomized trial. The study included 3,242 children < 12 months of age living in 30 municipalities from five regions of Brazil. The choice of states and municipalities was intentional, based on the implementation of the Brazilian Happy Child Program. The sample was selected among eligible children for the Brazilian Happy Child Program, and the objective was the promotion of infant development. The Ages and Stages Questionnaire (ASQ) was used to assess infant development. A three-level analytical model (state, municipality, and individuals), using the Wald test for heterogeneity and linear trend, estimated the mean ASQ-3 and 95% confidence interval (95%CI). The analyses were adjusted for potential confounders. Information was analyzed for 3,061 (94.4%) children with available data for ASQ-3. Infant development scores (total and in all the domains) were some 12% lower in preterm children and those with intrauterine growth restriction (small for gestational age). Lower scores were seen in children of mothers with low schooling, depressive symptoms, two or more children under seven years of age living in the household, and who did not report self-perceived support or help during the pregnancy. In conclusion, potentially modifiable characteristics (schooling, maternal depression, and prematurity/intrauterine growth restriction) showed greater impact on reducing the infant development score in all the target domains.


Resumen: El objetivo fue evaluar los factores socioeconómicos, familiares e individuales, asociados al desarrollo infantil en el primer año de vida, entre familias con vulnerabilidad social. Se trata de un análisis transversal, con datos de la base de referencia de un ensayo aleatorio. El estudio incluyó a 3.242 niños < 12 meses de edad, residentes en 30 municipios de cinco regiones de Brasil. La elección de estados y municipios fue intencional, considerando como base la implementación del Programa Niño Feliz. La muestra se seleccionó a partir de niños elegibles para el Programa Niño Feliz, cuyo objetivo es promover la estimulación y el desarrollo infantil. Se utilizó el Ages and Stages Questionnaire (ASQ) para la evaluación del desarrollo infantil. Un modelo de análisis multinivel en tres niveles (estado, municipio e individuos), usando el test de Wald para la heterogeneidad y tendencia lineal, estimó la media del ASQ-3 y el intervalo de 95% de confianza (IC95%). Los análisis se ajustaron para potenciales factores de confusión. Se analizó información de 3.061 (94,4%) niños con datos disponibles para ASQ-3. Las puntuaciones de desarrollo infantil (total y en todos los dominios) fueron cerca de un 12% menores en niños nacidos pretérmino y con restricción del crecimiento intrauterino (pequeños para la edad gestacional). Se observaron menores puntuaciones en hijos de madres con baja escolaridad, con síntomas de depresión, con dos o más niños menores de siete años residiendo en el domicilio y que no informaron autopercepción de apoyo/ayuda durante la gestación. Se concluye que las características potencialmente modificables (escolaridad, depresión materna y prematuridad/restricción del crecimiento intrauterino) presentaron un mayor impacto en la reducción de la puntuación de desarrollo en todos los dominios evaluados.


Subject(s)
Humans , Female , Infant, Newborn , Infant , Child Development , Socioeconomic Factors , Brazil , Infant, Low Birth Weight , Program Evaluation , Randomized Controlled Trials as Topic , Cross-Sectional Studies , Mothers
3.
Cad. Saúde Pública (Online) ; 38(1): e00003121, 2022. tab, graf
Article in Portuguese | LILACS | ID: biblio-1355984

ABSTRACT

Resumo: A mortalidade perinatal engloba a mortalidade fetal e a neonatal precoce (0 a 6 dias). Este estudo descreveu os óbitos perinatais ocorridos no Brasil em 2018, segundo a classificação de Wigglesworth modificada. As fontes de dados foram os Sistemas de Informações sobre Mortalidade e sobre Nascidos Vivos. Foram calculadas as taxas de mortalidade fetal e perinatal por mil nascimentos totais (nascidos vivos mais natimortos) e a taxa de mortalidade neonatal precoce por mil nascidos vivos, e comparadas usando seus respectivos intervalos de 95% de confiança (IC95%). Os óbitos perinatais foram classificados nos grupos de causas anteparto, anomalias congênitas, prematuridade, asfixia e causas específicas. Foi calculado, para cada grupo de causas, o número de óbitos por faixa de peso, além das taxas de mortalidade e os respectivos IC95%, e feita a distribuição espacial das taxas de mortalidade por Unidade da Federação (UF). Foram registrados 35.857 óbitos infantis, sendo 18.866 (52,6%) neonatais precoces; os natimortos somaram 27.009. Os óbitos perinatais totalizaram 45.875, perfazendo uma taxa de mortalidade de 15,5‰ nascimentos. A maior taxa de mortalidade (7,6‰; 7,5‰-7,7‰) foi observada no grupo anteparto, seguido da prematuridade (3,6‰; 3,6‰-3,7‰). No grupo anteparto, 14 das 27 UFs (sendo oito na Região Nordeste e quatro na Região Norte) apresentaram as taxas de mortalidade perinatal acima da nacional. A taxa de mortalidade perinatal no Brasil mostrou-se elevada, e a maioria dos óbitos poderia ser prevenida com investimento em cuidados pré-natais e ao nascimento.


Abstract: Perinatal mortality includes fetal mortality and early neonatal mortality (0 to 6 days of life). The study described perinatal deaths in Brazil in 2018 according to the modified Wigglesworth classification. The data sources were the Brazilian Mortality Information System and the Brazilian Information System on Live Births. Fetal mortality and perinatal mortality rates were calculated per 1,000 total births (live births plus stillbirths) and the early neonatal mortality rate per 1,000 live births, compared using their respective 95% confidence intervals (95%CI). Perinatal deaths were classified in groups of antepartum causes, congenital anomalies, prematurity, asphyxia, and specific causes. For each group of causes, the study calculated the number of deaths by weight group, in addition to mortality rates and respective 95%CI, besides the spatial distribution of mortality rates by state of Brazil. A total of 35,857 infant deaths were recorded, of which 18,866 (52.6%) were early neonatal deaths, while stillbirths totaled 27,009. Perinatal deaths totaled 45,875, for a mortality rate of 15.5‰ births. The highest mortality rate (7.6‰; 7.5‰-7.7‰) was observed in the antepartum group, followed by prematurity (3.6‰; 3.6‰-3.7‰). In the antepartum group, 14 of the 27 states (eight of which in the Northeast and four in the North) presented perinatal mortality rates above the national rate. Perinatal mortality in Brazil was high, and most deaths could have been prevented with investment in prenatal and childbirth care.


Resumen: La mortalidad perinatal engloba la mortalidad fetal y neonatal precoz (0 a 6 días). Este estudio describió los óbitos perinatales ocurridos en Brasil en 2018, según la clasificación de Wigglesworth modificada. Las fuentes de datos fueron los Sistemas de Información sobre Mortalidad y sobre Nacidos Vivos. Se calcularon las tasas de mortalidad fetal y perinatal por 1.000 nacimientos totales (nacidos vivos más mortinatos) y la tasa de mortalidad neonatal precoz por 1.000 nacidos vivos, y se compararon usando sus respectivos intervalos de 95% de confianza (IC95%). Los óbitos perinatales se clasificaron en los grupos de causas: anteparto, anomalías congénitas, prematuridad, asfixia y causas específicas. Se calculó, para cada grupo de causas, el número de óbitos por franja de peso, además de las tasas de mortalidad y los respectivos IC95%, y se realizó la distribución espacial de las tasas de mortalidad por Unidad de la Federación (UF). Se registraron 35.857 óbitos infantiles, siendo 18.866 (52,6%) neonatales precoces; los mortinatos sumaron 27.009. Los óbitos perinatales totalizaron 45.875, ascendiendo a una tasa de mortalidad de un 15,5‰ nacimientos. La mayor tasa de mortalidad (7,6‰; 7,5‰-7,7‰) se observó en el grupo anteparto, seguido de la prematuridad (3,6‰; 3,6‰-3,7‰). En el grupo anteparto, 14 de las 27 UFs (estando ocho en la región Nordeste y cuatro en la región Norte) presentaron tasas de mortalidad perinatal por encima de la nacional. La tasa de mortalidad perinatal en Brasil se mostró elevada y la mayoría de los óbitos podría ser prevenido con inversión en cuidados prenatales y en el nacimiento.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Infant , Perinatal Death , Brazil/epidemiology , Infant, Low Birth Weight , Infant Mortality , Perinatal Mortality
4.
Rev. Ciênc. Méd. Biol. (Impr.) ; 20(3): 400-405, dez 20, 2021. fig
Article in Portuguese | LILACS | ID: biblio-1354253

ABSTRACT

Introdução: alterações no padrão de crescimento de recém-nascidos prematuros podem ter implicações para sua saúde futura. A literatura dispõe de diversas ferramentas e pontos de corte para avaliação da sua adequação, logo, diferentes diagnósticos podem ser obtidos a depender do parâmetro adotado. Objetivo: determinar a diferença no diagnóstico de Retardo de Crescimento Extrauterino em prematuros, durante internamento hospitalar, conforme as curvas de Fenton e Intergrowth. Metodologia: trata-se de estudo transversal, com dados secundários, coletados durante o internamento em unidade de terapia intensiva e de cuidados intermediários convencionais neonatais de uma maternidade pública, em 2019, Coletaram-se medidas de peso e perímetro cefálico ao nascer e no momento da alta/transferência e calcularam-se seus respectivos indicadores antropométricos de acordo com as duas curvas. Utilizaramse duas classificações para o Retardo: diagnóstico de Pequeno para Idade Gestacional na alta/transferência; queda no escore Z dos indicadores maior ou igual a 1 entre o nascimento e a alta/transferência. Resultados: Não houve diferença em relação ao número de crianças classificadas como Pequeno para Idade Gestacional ao nascer, entre as curvas. Porém, no momento da alta/transferência houve maior prevalência de Pequeno para a Idade Gestacional/Retardo de Crescimento Extrauterino, de acordo com Fenton (73,6% versus 64,9%). A análise longitudinal dos indicadores de crescimento para caracterização do referido retardo por meio da curva de Fenton também detectou maior número de diagnósticos. Conclusão: conclui-se que o diagnóstico do retardo apresentou diferenças entre os referenciais. Os parâmetros de Fenton determinaram maior ocorrência dele no momento do desfecho, independente da realização da avaliação transversal ou longitudinal dos indicadores.


Introduction: changes in growth pattern of preterm infants may have implications for their future health. Literature has several tools and cutoff points to assess its adequacy, therefore, different diagnosis may be obtained depending on the adopted parameter. Objective: determine the difference in diagnosis of extrauterine growth restriction (EUGR) in preterm infants during hospitalization based on Fenton 2013) and Intergrowth-21 (2014) curves. Methods: this is a cross-sectional study with secondary data which were collected during hospitalization in an intensive care unit and neonatal conventional intermediate care in a public maternity hospital, in 2019. Results: weight and head circumference measurements were collected at birth and at discharge/transfer and their respective anthropometric indicators were calculated according to Fenton and Intergrowth-21 curves. The following EUGR criteria were used: diagnosis of small for gestational age (SGA) at discharge/transfer; decrease in Z score for indicators higher or equal to 1 between birth and discharge/transfer. There was no difference in the number of children classified as SGA at birth between the curves. However, at the time of discharge/ transfer there was a higher prevalence of SGA/EUGR according to Fenton (73.6% versus 64.9%). Longitudinal analysis of growth indicators for EUGR using Fenton curve also detected a higher number of patients with EUGR. Conclusion: the conclusion is that EUGR diagnosis showed differences between Fenton and Intergrowth methods. Fenton's parameters determined a higher occurrence of EUGR at the time of outcome, regardless of whether indicators were cross-sectionally or longitudinally evaluated.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant, Low Birth Weight , Infant, Premature , Child Development , Growth , Infant, Premature, Diseases , Cross-Sectional Studies , Gestational Age
5.
Univ. salud ; 23(3): 179-188, sep.-dic. 2021. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1341764

ABSTRACT

Resumen Introducción: El Bajo Peso al Nacer (BPN) tiene múltiples causas y continúa siendo un problema que afecta diferentes regiones de Colombia. Objetivo: Determinar los factores asociados con BPN en el Hospital Universitario Departamental de Nariño. Materiales y métodos: Estudio de casos y controles que incluyó madres y recién nacidos, cuyo parto fue atendido entre noviembre de 2014 y junio de 2015. Resultados: El riesgo de BPN fue mayor en mujeres con edad entre 10-19 años (OR=7,79, IC95%=2,61-23,23), con antecedente de infección vaginal durante el embarazo (OR=4, IC95%=1,26-12,66), nivel educativo primaria incompleta (OR=10,93, IC95%=1,51-79,13) o primaria completa (OR=2,94, IC95%=1,06-8,13), afiliadas al régimen de salud subsidiado (OR=4,96, IC95%=1,71-14,41). El riesgo de tener un recién nacido con BPN se redujo un 10% (OR=0,90, IC95%=0,84-0,96) por cada incremento en una unidad de Índice de Masa Corporal y un 76% (OR=0,23, IC95%=0,16-0,34) por cada incremento en una semana de gestación. Conclusiones: La mayoría de factores de riesgo identificados pueden ser prevenidos o intervenidos precozmente desde un enfoque de salud pública.


Abstract Introduction: Low Birth Weight (LBW) has multiple causes and continues to be a problem that affects different regions of Colombia. Objective: To determine factors associated with LBW in the Departmental University Hospital of Nariño (Colombia). Materials and methods: A case-control study that included newborns and mothers whose delivery took place between November 2014 and June 2015. Results: Risk of LBW was higher in: women aged between 10-19 years (OR=7.79, 95%CI=2.61-23.23); with history of vaginal infection during pregnancy (OR=4, 95%CI=1.26-12.66); and those affiliated with the subsidized health regimen (OR=4.96, 95%CI=1.71-14.41). The risk of having a newborn with LBW was reduced by 10% (OR=0.90, 95%CI=0.84-0.96) for each one unit increase in Body Mass index, and by 76% (OR=0.23, 95%CI=0.16-0.34) for each increase in one week of gestation. Conclusions: Most of the identified risk factors can be prevented or intervened with through an early public health approach.


Subject(s)
Infant, Low Birth Weight , Risk Factors , Prenatal Care , Pregnancy , Logistic Models
6.
Rev. bras. ginecol. obstet ; 43(11): 811-819, Nov. 2021. tab
Article in English | LILACS | ID: biblio-1357071

ABSTRACT

Abstract Objective To investigate the characteristics of women who had preterm birth (PTB) and related outcomes according to ethnicity. Methods A secondary analysis of a multicenter cross-sectional study conducted in Brazil. Women who had PTB were classified by self-report as white and non-white. Clinical, pregnancy, and maternal data were collected through postpartum interviews and reviews of medical charts. The sociodemographic, obstetric and clinical characteristics of the women, as well as the mode of delivery and the neonatal outcomes among different ethnic groups were compared through a bivariate analysis. Results Of the 4,150 women who had PTB, 2,317 (55.8%) were non-white, who were more likely: to be younger than 19 years of age (prevalence ratio [PR]: 1.05; 95% confidence interval [95%CI]: 1.01-1.09); to be without a partner; to live on low income; to have lower levels of schooling; to have ≥ 2 children; to perform strenuous work; to be fromthe Northeastern region of Brazil rather than the from Southern region; to have a history of ≥ 3 deliveries; to have an interpregnancy interval<12 months; to have pregnancy complications such as abortion, PTB, preterm premature rupture of membranes (pPROM), and low birth weight; to initiate antenatal care (ANC) visits in the second or third trimesters; to have have an inadequate number of ANC visits; to be under continuous overexertion; to smoke in the first and second or third trimesters; and to have anemia and gestational hypertension. The maternal and neonatal outcomes did not differ between the groups, except for the higher rate of low birth weight (73.7% versus 69.0%) in infants born to non-white women, and the higher rate of seizures (4.05% versus 6.29%) in infants born to white women. Conclusion Unfavorable conditions weremore common in non-whites than inwhites. Proper policies are required to decrease inequalities, especially in the context of prematurity, when women and their neonates have specific needs.


Resumo Objetivo Investigar as características das mulheres com parto pré-termo e os respectivos resultados de acordo com a etnia. Métodos Uma análise secundária de umestudo de corte transversalmulticêntrico no Brasil. Mulheres com parto pré-termo foram classificadas por autodefinição como brancas ou não brancas. Dados maternos, clínicos, e da gestação foram coletados por entrevista pós-parto e revisão de prontuários. As características sociodemográficas, obstétricas e clínicas das mulheres, o tipo de parto, e os resultados neonatais dos grupos étnicos foram comparados por análise bivariada. Resultados Das 4.150 mulheres que tiveram parto pré-termo, 2.317 (55,8%) eram não brancas, que com mais frequência: eram menores de 19 anos de idade (razão de prevalência [RP]: 1,05; intervalo de confiança de 95% [IC95%]: 1,01-1,09); não tinham parceiro; eramde baixa renda; tinham baixa escolaridade; tinham ≥ 2 filhos; realizavam trabalho extenuante; provinhammais do Nordeste do que do Sul; tinham histórico de ≥ 3 partos; tinham intervalo interpartal<12 meses; e tiveram complicações gestacionais como aborto, parto pré-termo, rotura prematura de membranas pré-termo (RPM-PT) e baixo peso ao nascimento; iniciaram as consultas de pré-natal no segundo ou terceiro trimestres; comparecerama um número inadequado de consultas; viviam sob contínua exaustão; fumaram no primeiro e segundo ou terceiro trimestres; e tiveram anemia e hipertensão gestacional. Os resultados maternos e neonatais não diferiram entre os grupos, exceto pelamaior taxa de baixo peso ao nascimento (73,7% versus 69,0%) entre as crianças das mulheres não brancas, e e a maior taxa de convulsões (4,05% versus 6,29%) entre as das brancas. Conclusão Condições desfavoráveis foram mais comuns entre não brancas do que entre brancas. Políticas apropriadas são necessárias para diminuir as diferenças, especialmente no contexto da prematuridade, quando mulheres e seus neonatos têm necessidades específicas.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Infant , Child , Premature Birth/epidemiology , Brazil/epidemiology , Infant, Low Birth Weight , Ethnic Groups , Cross-Sectional Studies
7.
Ciênc. Saúde Colet ; 26(supl.3): 5383-5392, Oct. 2021. tab, graf
Article in Portuguese | LILACS | ID: biblio-1345733

ABSTRACT

Resumo Evidências recentes apontam para a influência de processos inflamatórios periodontais na ocorrência de baixo peso ao nascer. Embora muitos estudos empregaram métodos robustos de investigação, ainda não existe consenso sobre o tópico. Analisar sistematicamente a relação entre a periodontite materna e o baixo peso ao nascer. A busca por estudos foi realizada até abril de 2019. Os delineamentos de estudos incluídos foram coorte e caso-controle que estimaram a associação entre a periodontite e o baixo peso ao nascer, sem limite quanto ao idioma ou data da publicação. Análise de heterogeneidade dos estudos, análises de subgrupo e metanálises com modelo de efeitos randômicos foram realizadas. Foram estimadas as medidas de associação sumária por meio da Odds Ratio bruta e ajustada, com respectivos intervalos de confiança a 95%. A inspeção visual de gráficos foi empregada para avaliar viés de publicação. Um total de 21 artigos foram identificados e todos foram selecionados para a metanálise. O modelo final aponta que a periodontite em gestantes se associou ao baixo peso ao nascer (ORbruta=2,13; IC95%=1,60-2,83; I2=80,0% e ORajustada=2,64; IC95%=2,04-3,42; I2=17,4%). Gestantes com periodontite podem ter mais que o dobro de probabilidade de terem filhos com baixo peso ao nascer.


Abstract Recent evidence points to the influence of periodontal inflammatory processes on the occurrence of low birth weight. Although many studies employed robust investigation methods, there is still no general agreement on the relationship between maternal periodontitis and low birth weight. The search for studies was conducted until April 2019. The studies included cohort and case-control studies that estimated the association between periodontitis and low birth weight, with no restriction on language or date of publication. Analysis of the heterogeneity of studies, subgroup analyses and meta-analyses with a random effects model were performed. Summary association measurements were estimated using the crude and adjusted Odds Ratio, with respective 95% confidence intervals. Visual inspection of graphs was used to assess publication bias. A total of 21 articles were identified, all of which were selected for the meta-analysis. The final model indicates that periodontitis in pregnant women was associated with low birth weight (ORgross=2.13; CI95%=1.60-2.83; I2=80.0% and ORadjusted=2.64; CI95%=2.04-3.42; I2=17.4%). Pregnant women with periodontitis may be more than twice as likely to have low birth weight babies.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Periodontitis/epidemiology , Infant, Low Birth Weight , Case-Control Studies , Cohort Studies , Pregnant Women
8.
Rev. Ciênc. Méd. Biol. (Impr.) ; 20(2): 221-228, set 29, 2021. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1354388

ABSTRACT

Objetivo: comparar três critérios de definição da periodontite na associação da doença periodontal com o baixo peso ao nascer (BPN) em uma população de puérperas jovens de Salvador, BA. Metodologia: aplicaram-se três diferentes critérios de definição da periodontite a uma amostra de 202 mães de bebês com peso ≥ 2.500g (controles) e de 97 mães de bebês com BPN (casos) pertencentes a uma base de dados de um estudo caso-controle prévio. Para a análise da associação entre periodontite e BPN, construíram-se modelos para os três critérios. A regressão logística não-condicional foi realizada para estimar a Odds Ratio (OR) baseada em Intervalos de Confiança a 95%. Resultados: a idade média das mães foi de 26,29 anos. A maioria declarou-se negra/ parda (92.64%), não fumante (94,65%) e possuir renda de até um salário-mínimo (61,20%). A ocorrência da periodontite variou de 22,41% a 94,31%, segundo o critério usado. Estimando-se a OR ajustada, a periodontite definida pelo critério 1 [ORajust. = 0,94, IC (95%)= 0,56­1,56], critério 2 [ORajust=1,18, IC(95%)= 0,65-2,13] e critério 3 [ORajust= 0,87, IC(95%)=0,37-3,22] não esteve associada com o BPN. Conclusão: flexibilizar o critério de definição interferiu na magnitude das medidas de ocorrência, mas não influenciou a análise de associação entre a periodontite e o BPN.


Objective: to compare three criteria for periodontitis definition and its association with Low Birth Weight (LBW) in a population of young mothers, in the city of Salvador ­ BA. Methods: Three different definitions for periodontitis were applied to sample of 202 mothers of newborns (NB) weighing ≥2.500g (controls) and 97 mothers of NB with LBW (cases) belonging to database from a previous case-control study. For the analysis of the association between periodontitis and LBW, were created models for three criteria. An unconditional logistic regression was used to estimate the odds ratio (OR) with 95% confidence interval. Results: the average age of mothers was 26,29 years. Most respondents identified themselves as black or brown (92.64%), 94,65% nonsmokers (94,65%) and have income up to 1 minimum wage (61.20%). The occurrence of periodontitis varied between 22,41% to 94,31% according to the criteria. When estimating adjusted OR, the periodontitis defined by criterion 1 [ORajus=0,94, IC(95%)=0,56­1,56], criterion 2 [ORajus=1,18, IC(95%)= 0,65-2,13] and criterion 3 [ORajus=0,87, IC(95%)=0,37-3,22] did not demonstrate association with LBW. Conclusion: to flex periodontitis' criteria modified the magnitude of measures of occurrence but did not influence the association analysis between periodontitis and the BPN.


Subject(s)
Humans , Male , Female , Infant, Newborn , Adult , Periodontitis , Infant, Low Birth Weight , Young Adult , Poverty , Case-Control Studies , Retrospective Studies , Observational Study , Non-Smokers , Gender Identity
9.
Rev. cuba. oftalmol ; 34(3): e1044, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1352022

ABSTRACT

Objetivo: Evaluar la asociación entre los factores de riesgo en pacientes miopes en edad pediátrica. Métodos: Se realizó un estudio con diseño de casos y control para evaluar los factores de riesgo asociados a la miopía en los pacientes atendidos en la consulta del Servicio de Oftalmología Pediátrica del Instituto Cubano de Oftalmología "Ramón Pando Ferrer". La muestra estuvo conformada por 263 pacientes (123 casos y 140 controles) que cumplieron los criterios de inclusión y de exclusión. Las variables del estudio fueron la edad, el sexo, el color de la piel, la zona de procedencia, el bajo peso al nacer, la prematuridad, las madres fumadoras, el antecedente de familiares con defectos refractivos, las horas de exposición a las pantallas, las horas de exposición a la luz solar y la longitud axial. Resultados: Se encontró correlación entre el antecedente de familiares con defecto refractivo y la presencia de miopía (p = 0,009), y a su vez un riesgo de 1,9 de padecerla; más de 2 horas - pantallas se relaciona con pacientes miopes (p = 0,003) y duplica el riesgo. Más de 2 horas de luz solar fue más frecuente en los controles (p = 0,004) y es un factor de protección; las longitudes axiales fueron mayores en miopes (p = 0,000) y se correlacionó la exposición horas - pantallas con una mayor longitud axial. Conclusiones: Los antecedentes familiares de defectos refractivos aumentan 1,9 veces el riesgo de padecer miopía; la exposición a las pantallas por más de 2 horas al día lo duplica y la exposición a la luz solar por el mismo tiempo lo reduce a la mitad. La longitud axial es mayor en miopes y en los expuestos a las pantallas(AU)


Objective: Evaluate the association between risk factors in pediatric myopic patients. Methods: A case-control study was conducted to evaluate the risk factors associated to myopia in patients attending the Pediatric Ophthalmology Service at Ramón Pando Ferrer Cuban Institute of Ophthalmology. The sample was 263 patients (123 cases and 140 controls) who met the inclusion criteria. The study variables were age, sex, skin color, place of residence, low birth weight, prematurity, smoking mothers, a family history of refractive defects, screen time, sun exposure hours and axial length. Results: A correlation was found between a family history of refractive defects and the presence of myopia (p = 0.009), as well as a 1.9 risk of developing the disorder. More than two screen hours were associated to myopic patients (p = 0.003), doubling the risk. More than two sun exposure hours were more frequent among controls (p = 0.004) and constitute a protection factor. Axial lengths were greater among myopics (p = 0.000). Exposure and screen time were correlated with greater axial length. Conclusions: A family history of refractive defects increases the risk for myopia 1.9 times, exposure to screens for more than two hours per day doubles it, and the same number of sun exposure hours reduces it to half. Axial length is greater among myopics and screen exposed people(AU)


Subject(s)
Humans , Child , Adolescent , Infant, Low Birth Weight , Risk Factors , Myopia/etiology , Case-Control Studies , Screen Time
10.
Más Vita ; 3(3): 8-21, sept. 2021. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1343291

ABSTRACT

Analizar la evolución del síndrome de distrés respiratorio agudo (SDRA) en neonatos pretérminos del área de cuidados intensivos del Hospital General Delfina Torres de Concha. Materiales y Métodos: La investigación es un estudio cuantitativo, de corte transversal y alcance descriptivo. La muestra probabilística quedó conformada por 49 madres de neonatos prematuros. Las técnicas utilizadas son el estudio documental y la encuesta. Los criterios de inclusión incluyeron ambos sexos, que nacieron entre las 26 y las 35 semanas de gestación, durante los meses de julio, agosto y septiembre de 2020. Las variables fueron los factores sociodemográficos de las madres, los factores de riesgo maternos, el género, vía del parto, peso al nacer, complicaciones de los neonatos y la mortalidad infantil. Resultados: Los resultados muestran que la etnia prevalente fue la mestiza (65,3%), el estado civil más representado fue el de unión libre (51,0%) y el nivel de escolaridad es muy bajo, así como el per cápita económico familiar. Los factores de riesgo maternos fueron la hipertensión (21,5%), la edad y la preeclamsia (18,5%, respectivamente). En los recién nacidos prevaleció el sexo masculino (46,9%) sobre el femenino (53.06%), al igual que las cesáreas (55,1%). Las complicaciones más importantes fueron la hemorragia intraventricular (23,8%), la hipertensión pulmonar persistente (20,6%) y la displasia broncopulmonar (15,9%). La tasa de mortalidad infantil se situó en el 32,7%. Conclusiones: Existe una correlación entre las complicaciones severas de los recién nacidos y la mortalidad neonatal. Por la trascendencia familiar y social del fallecimiento de neonatos y la frecuencia de trastornos respiratorios en la morbimortalidad de los recién nacidos en dicho Hospital, se hace necesario realizar estudios que estimulen la prevención y diagnóstico oportuno, especialmente en contextos como el nuestro


To analyze the evolution of acute respiratory distress syndrome (ARDS) in preterm neonates in the intensive care area of the Hospital General Delfina Torres de Concha. Materials and Methods: The research is a quantitative, cross-sectional, descriptive study. The probabilistic sample consisted of 49 mothers of preterm infants. The techniques used were documentary study and survey. The inclusion criteria included both sexes, born between 26 and 35 weeks of gestation, during the months of July, August and September 2020. The variables were sociodemographic factors of the mothers, maternal risk factors, gender, and route of delivery, birth weight, neonatal complications and infant mortality. The results: The results show that the most prevalent ethnic group was mestizo (65.3%), the most represented marital status was a union (51.0%) and the level of schooling was very low, as well as the family economic per capita. Maternal risk factors were hypertension (21.5%), age and preeclamsia (18.5%, respectively). Among the newborns, the male sex (46.9%) prevailed over the female (53.06%), as did cesarean sections (55.1%). The most important complications were intraventricular hemorrhage (23.8%), persistent pulmonary hypertension (20.6%) and bronchopulmonary dysplasia (15.9%). The infant mortality rate was 32.7%. Conclusions: There is a correlation between severe newborn complications and neonatal mortality. Due to the family and social importance of neonatal deaths and the frequency of respiratory disorders in the morbidity and mortality of newborns in this Hospital, it is necessary to carry out studies to stimulate prevention and timely diagnosis, especially in contexts such as ours


Subject(s)
Humans , Male , Female , Infant, Newborn , Pregnancy Complications , Respiratory Distress Syndrome, Newborn/mortality , Infant, Low Birth Weight , Infant, Premature , Social Class , Intensive Care Units, Neonatal , Cesarean Section , Surveys and Questionnaires , Educational Status , Age Groups
11.
Medisan ; 25(4)2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1340209

ABSTRACT

Introducción: El peso al nacer es, sin dudas, la variable más importante para determinar las posibilidades que tiene de un recién nacido de experimentar un crecimiento y desarrollo satisfactorios, de manera que la tasa de recién nacidos con bajo peso se considera hoy día un indicador general de salud. Objetivo: Describir los factores de riesgo asociados al bajo peso al nacer en el Policlínico Universitario de Previsora, de la ciudad de Camagüey durante 2019. Métodos: Se realizó un estudio descriptivo, de corte transversal de las 19 madres que tuvieron recién nacidos con peso inferior a 2 500 gramos y se encontraban en el área de salud señalada en el periodo estudiado. Se analizaron variables relacionadas con los factores sociodemográficos, medioambientales y con la gestación. Para el procesamiento de los datos se utilizaron frecuencias relativas y absolutas. Resultados: Las enfermedades más frecuentes relacionadas con estos nacimientos fueron la hipertensión arterial y la anemia (26,3 %, respectivamente); asimismo, 57,8 % de las madres eran multíparas y 3 de ellas presentaron un periodo intergenésico corto. Conclusiones: El bajo peso al nacer se debe a la asociación de varios factores biológicos, socioeconómicos, ambientales y psicológicos, por lo que resulta difícil definir una causa única en su aparición.


Introduction: The birth weight is, undoubtedly, the most important variable to determine the possibilities that a new born has experiencing a satisfactory growth and development, so that the rate of new born with low weight is considered nowadays a general indicator of health. Objective: To describe the risk factors associated with the low birth weight in the University Polyclinic of Previsora, from Camagüey city during 2019. Methods: A descriptive and cross-sectional study of the 19 mothers that had new borns with weight under 2 500 grams was carried out. They were in that health area during the studied period. Some variables related to the sociodemographic, environmental factors and with pregnancy were analyzed. Relative and absolute frequencies were used to process the data. Results: The most frequent diseases related to these births were hypertension and anemia (26.3 %, respectively); also, 57.8 % of the mothers were multiparus and 3 of them presented one short intergenesic period. Conclusions: Low birth weight is the consequence of several biological, socioeconomic, environmental and psychological factors, reason why it is difficult to define a unique cause in its emergence.


Subject(s)
Infant, Low Birth Weight , Maternal and Child Health , Risk Factors , Primary Health Care , Infant Mortality , Perinatal Care
12.
Rev. Bras. Saúde Mater. Infant. (Online) ; 21(3): 805-815, July-Sept. 2021. tab, graf
Article in English | LILACS | ID: biblio-1347002

ABSTRACT

Abstract Objectives: to analyze factors associated with neonatal death among adolescent mothers. Methods: randomized hospital-based cross-sectional study in a tertiary institution,, data from the Sistema de Informação sobre Nascidos Vivos (Sinasc), (Live Birth Information System), Sistema de Informação sobre Mortalidade (SIM) (Mortality Information System), and medical records. The study population was comprised of 1,341 adolescents aged 10-19 who had assisted childbirth at the institution between 2012 to 2016. The independent variables were sociodemographic characteristics, care, prenatal, childbirth, birth, and newborn's hospitalization, as well as the baby's characteristics. Logistic regression analysis was carried out to assess the association between neonatal death and explanatory variables. Results: the factors associated with death were from the countryside or other States (OR=2.68; CI95% =1.24-5.81), Apgar scores lower than 7 in the 1st (OR= 9.52; CI95% = 4.15-21.81) and the 5th (OR=4.17; CI95%=1.53-11.34) minutes of life; and birth weight less than 999g (OR=13.37; CI95% =3, 64-49.04) and between 1,500 to 2,499g (OR=3.43; CI95%=1.37-8.58). Conclusions: apgar and low birth weight were associated with the neonatal death among adolescent mothers, as well as the fact they come from the countryside and other States. These findings show, in addition to classic risks, potential difficulties for adolescents in having access to healthcare services in their hometown. To reduce the risks, there is a need for restructuring the maternal and child healthcare network and ensure a social protection network for these girls.


Resumo Objetivos: analisar fatores associados ao óbito neonatal de mães adolescentes. Métodos: estudo transversal de base hospitalar em instituição terciária, randomizado, com dados do Sistema de Informação sobre Nascidos Vivos (Sinasc), Sistema de Informação sobre Mortalidade (SIM) e de prontuários. A população do estudo compreendeu 1.341 adolescentes de 10 a 19 anos assistidos durante o parto na instituição entre 2012 a 2016. As variáveis independentes foram características sociodemográficas, assistenciais, relacionadas ao pré-natal, parto, nascimento e internamento do recém-nascido, além das características do bebê. Realizou-se análise de regressão logística para avaliar a associação entre óbito neonatal e variáveis explanatórias. Resultados: os fatores associados ao óbito foram municípios do interior e outros estados (OR=2,68; IC95%=1,24-5,81), índices de apgar menor que sete no 1º(OR=9,52; IC95%=4,15-21,81) e no 5º(OR=4,17; IC95%=1,53-11,34) minutos de vida e peso ao nascer menor que 999g (OR=13,37; IC95%= 3,64-49,04) e entre 1500 a 2499g (OR=3,43; IC95%= 1,37-8,58). Conclusões: o apgar e o baixo peso ao nascer se associaram ao óbito neonatal de mães adolescentes além da procedência de municípios do interior e outros estados. Estes achados mostram além de riscos clássicos, potenciais dificuldade das adolescentes em dispor de assistência nos seus lugares de residência. Para reduzir os riscos há necessidade de reorganizar a rede assistencial materno-infantil e garantir uma rede de proteção social a estas meninas.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Child , Adolescent , Adult , Pregnancy in Adolescence , Risk Factors , Cause of Death , Perinatal Death/etiology , Apgar Score , Prenatal Care , Socioeconomic Factors , Tertiary Healthcare , Brazil , Infant, Low Birth Weight , Cross-Sectional Studies , Maternal-Child Health Services
13.
Rev. Bras. Saúde Mater. Infant. (Online) ; 21(2): 399-408, Apr.-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1340648

ABSTRACT

Abstract Objectives: describe mothers, pregnancies and newborns' characteristics according to the type of childbirth history and to analyze repeated cesarean section (RCS) and vaginal delivery after cesarean section (VBACS), in São Paulo State in 2012. Methods: data are from the Sistema de Informações sobre Nascidos Vivos (Live Birth Information Systems). To find the RCS's group, the current type of childbirth equal to cesarean section was selected and from these all the previous cesareans. To identify the VBACS's group all live birth with current vaginal delivery were selected and from these all previous cesareans. Mothers with a history of RCS and VBACS were analyzed according to the characteristics of the pregnancy, newborn and the childbirth hospital. Results: 273,329 mothers of live birth with at least one previous child were studied. 43% of these were born of RCS and 7.4% of VBACS. Mothers who underwent RCS are older and higher educated and their newborns presented a lower incidence of low birth weight. Early term was the most frequent rating for gestational age born of RCS. Live births were of VBACS and had greater proportions of late term. The RCS was more common in hospitals not affiliated with the Sistema Único de Saúde (SUS) (Public Health System) (44.1%). Conclusion: the high RCS's rates, especially in the private sector, highlight the necessity of improvements in childbirth care model in São Paulo.


Resumo Objetivos: descrever características das mães, da gestação e do recém-nascido, segundo histórico de tipo de parto, analisando repetição de cesárea (RC) e parto vaginal após cesárea (PVAC), no Estado de São Paulo, em 2012. Métodos: os dados são provenientes do Sistema de Informações sobre Nascidos Vivos. Para encontrar o conjunto RC, selecionou-se o tipo de parto atual igual a cesárea e destes buscou-se todos com cesárea anterior. Para identificar o grupo PVAC, selecionou-se os recém-nascido com parto atual vaginal e destes buscou-se todos com cesárea anterior. Foram analisadas mães com história de RC e PVAC, segundo características da gestação, do recémnascido e hospital do parto. Resultados: estudou-se 273.329 nascidos vivos de mães com pelo menos um filho anterior. Destes, 43% nasceram por RC e 7,4% por PVAC. As mães que realizaram RC são mais velhas e mais escolarizadas, seus recém-nascidos apresentaram menor proporção de baixo peso ao nascer. Termo precoce foi a mais frequente idade gestacional dos que nasceram por RC. Os recém-nascidos por PVAC apresentaram maiores proporções de termo tardio. RC foi mais frequente nos hospitais sem vínculo com o Sistema Único de Saúde (44,1%). Conclusão: as altas taxas de RC, principalmente no setor privado, evidenciam necessidade de melhoras no modelo de atenção ao parto em São Paulo.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Unified Health System , Cesarean Section/statistics & numerical data , Vaginal Birth after Cesarean/statistics & numerical data , Cesarean Section, Repeat/statistics & numerical data , Midwifery , Brazil/epidemiology , Infant, Low Birth Weight , Pregnant Women , Live Birth/epidemiology
14.
Arch. argent. pediatr ; 119(5): e480-e486, oct. 2021. ilus
Article in English, Spanish | LILACS, BINACIS | ID: biblio-1292126

ABSTRACT

El bajo peso al nacer (BP, < 2500 g), la restricción del crecimiento intrauterino (RCIU) y el parto prematuro (PP, < 37 semanas de gestación) son los factores clínicos más habituales para la programación alterada del número de nefronas y se asocian con un mayor riesgo de hipertensión, proteinuria y enfermedad renal futura en la vida. En la actualidad la evaluación indirecta del número total de nefronas mediante el uso de marcadores en el período posnatal representa el enfoque principal para evaluar el riesgo de evolución futura de los trastornos renales en los recién nacidos con BP, RCIU o PP.Se presentan los avances en la investigación en animales y sobre marcadores bioquímicos en humanos, y recomendaciones para la prevención del daño renal preconcepcional, incluidos los factores sociales y las enfermedades crónicas. La evidencia demuestra que la restricción de crecimiento y la prematuridad solas son capaces de modular la nefrogénesis y la función renal y, cuando son concurrentes, sus efectos tienden a ser acumulativos.


A low birth weight (LBW, < 2500 g), intrauterine growth restriction (IUGR), and preterm birth (PB, < 37 weeks of gestational age) are the most common clinical factors for an altered programming of nephron number and are associated with a greater risk for hypertension, proteinuria, and kidney disease later in life. At present, an indirect assessment of total nephron number based on postnatal markers is the most important approach to evaluate the risk for future kidney disorders in newborn infants with a LBW, IUGR or PB.Here we describe advances made in animal experiments and biochemical markers in humans, and the recommendations for the prevention of preconception kidney injury, including social factors and chronic diseases. According to the evidence, IUGR and prematurity alone can modulate nephrogenesis and kidney function, and, if occurring simultaneously, their effects tend to be cumulative.


Subject(s)
Humans , Animals , Female , Pregnancy , Infant, Newborn , Adult , Premature Birth , Kidney Diseases/etiology , Kidney Diseases/epidemiology , Infant, Low Birth Weight , Gestational Age , Kidney , Nephrons
15.
Ciênc. Saúde Colet ; 26(4): 1259-1264, abr. 2021. tab
Article in Portuguese | LILACS | ID: biblio-1285922

ABSTRACT

Resumo Diversos estudos indicam que a mortalidade para crianças do sexo masculino é maior do que a do feminino no Brasil. Estudos recentes também têm mostrado uma redução na sobremortalidade infantil masculina nos últimos anos. Entretanto, pouco se sabe sobre quais fatores estão associados a esse fenômeno. Como os bebês do sexo masculino são, em geral, mais frágeis, uma hipótese é de que melhorias no nível de renda e cuidados com a saúde pré e pós-natal tenham um impacto maior na redução da mortalidade infantil masculina. Dessa forma, o objetivo deste artigo foi analisar como esses fatores afetam a mortalidade no Brasil. Para a estimação do modelo, utilizaram-se dados estaduais do Brasil do período de 1996 a 2014. Os resultados indicam que a renda média, o baixo peso ao nascer, o número de consultas de pré-natal e a taxa de fecundidade são importantes fatores associados à mortalidade infantil no país. De modo geral, o impacto dessas variáveis é maior na mortalidade de crianças do sexo masculino, evidenciando que a maior fragilidade dessas crianças exige maior cuidado de pais e autoridades de saúde. Além disso, outros estudos podem analisar a importância do aleitamento materno sobre a mortalidade infantil e gênero no Brasil, de forma a verificar o impacto da amamentação na redução dos óbitos infantis.


Abstract Various studies reveal that male mortality is higher than female mortality among children in Brazil. Recent studies have also revealed a reduction in excess male infant mortality in the last few years. However, little is known about which factors are associated with this phenomenon. Since male infants are generally more susceptible, a potential hypothesis is that an improvement in income levels and pre- and post-natal healthcare have a greater impact on reducing male infant mortality. Thus, the scope of this article was to analyze how these factors affect infant mortality in Brazil. For the creation of the model, data for the period from 1996 to 2014 from Brazilian states were utilized. The results indicate that average income, low birth weight, the number of prenatal visits and the fertility rate, are important factors associated with infant mortality in the country. In general, the impact of these variables is greater in the mortality of male children, which would indicate that the higher susceptibility of male children requires greater care from the parents and the health authorities. Furthermore, future studies could analyze the importance of breastfeeding on infant mortality and gender in Brazil, in order to verify the impact of breastfeeding on the reduction of infant deaths.


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Infant , Child , Infant, Low Birth Weight , Infant Mortality , Prenatal Care , Brazil/epidemiology , Breast Feeding , Mortality
16.
Rev. bras. ginecol. obstet ; 43(4): 256-263, Apr. 2021. tab
Article in English | LILACS | ID: biblio-1280039

ABSTRACT

Abstract Objective To investigate the association between prenatal care (PNC) adequacy indexes and the low birth weigth (LBW) outcome. Methods A total of 368,093 live term singleton births in the state of Rio de Janeiro (Brazil) from 2015 to 2016 were investigated using data from the Brazilian Live Birth Information System (Sistema de Informações sobre Nascidos Vivos, SINASC, in Portuguese). Seven PNC adequacy indexes were evaluated: four developed by Brazilian authors (Ciari Jr. et al., Coutinho et al., Takeda, and an index developed and used by the Brazilian Ministry of Health - MS) and three by authors from other countries (Kessner et al., the Adequacy of Prenatal Care Utilization index - APNCU, and the Graduated Prenatal Care Utilization Index - GINDEX). Adjusted odds ratios were estimated for the PNC adequacy indexes by means of multivariate logistic regression models using maternal, gestational and newborn characteristics as covariates. Results When the PNC is classified as "inadequate", the adjusted odds ratios to the LBWoutcome increase between 42% and 132%, depending on which adequacy index is evaluated. Younger (15 to 17 years old) and older (35 to 45 years old) mothers, those not married, of black or brown ethnicity, with low schooling (who did not finish Elementary School), primiparous, with preterm births, as well as female newborns had increasing odds for LBW. The models presented areas under the receiver operating characteristic (ROC) curve between 80.4% and 81.0%, and sensitivity and specificity that varied, respectively, between 57.7% and 58.6% and 94.3% and 94.5%. Conclusion Considering all PNC adequacy indexes evaluated, the APNCU had the best discriminatory power and the best ability to predict the LBW outcome.


Resumo Objetivo Investigar a associação entre diferentes índices de adequação do cuidado pré-natal (PN) e o desfecho de nascimentos com baixo peso (BP). Métodos Foram investigados 368.093 nascimentos ocorridos no estado do Rio de Janeiro entre 2015 e 2016, utilizando-se as informações do Sistema de Informações sobre Nascidos Vivos (Sinasc). Sete índices de adequação do cuidado PN foram avaliados: quatro propostos por autores nacionais (Ciari Jr et al., Coutinho et al., Takeda, e um índice atualmente em uso pelo Ministério da Saúde - MS), e três, por autores internacionais (Kessner et al., Adequacy of Prenatal Care Utilization index - APNCU, e Graduated Prenatal Care Utilization Index - GINDEX). As razões de chance ajustadas para BP foram estimadas considerando os índices de adequação do cuidado PN por meio de modelos de regressão logística, utilizando características maternas, da gravidez e do recém-nascido como variáveis de controle. Resultados As chances ajustadas para ocorrência de BP ao nascer aumentam de 42% a 132%, a depender do índice empregado, quando o cuidado PN é considerado inadequado. Mães entre 15 e 17 anos e entre 35 e 45 anos, sem companheiro, de cor parda ou preta, com ensino fundamental incompleto, e primíparas, com gestações pré-termo, além de bebês do sexo feminino são fatores de risco para os nascimentos com BP. Conclusão Entre os índices avaliados, o APNCU foi o que apresentou melhor poder discriminatório e capacidade de prever o desfecho de BP ao nascer.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Adolescent , Adult , Young Adult , Prenatal Care/standards , Infant, Low Birth Weight , Parity , Brazil , Single Parent , Regression Analysis , Maternal Age , Marital Status , Educational Status , Race Factors , Middle Aged
17.
Int. j. med. surg. sci. (Print) ; 8(1): 1-10, mar. 2021.
Article in Spanish | LILACS | ID: biblio-1151625

ABSTRACT

El bajo peso al nacer constituye una preocupación mundial, los programas diseñados para prevenirlo dependen de la identificación de gestantes susceptibles. Existe escasa evidencia en la literatura acerca del cuidado por parte del profesional de enfermería dirigido a mujeres con factores de riesgo de tener niños con bajo peso al nacer desde la Atención Primaria de Salud. No obstante, hay teorías y modelos conceptuales que pueden ser aplicados para guiar las intervenciones. La teoría de los sistemas de enfermería es la que asumen los autores de esta investigación por considerarla de gran utilidad en la Salud Pública, debido a que, en el ámbito de la responsabilidad personal por la salud, centrar el autocuidado en la iniciativa propia de quienes lo requieren, entendiéndolo como "la práctica de actividades que los propios individuos, inician y desarrollan en su propio beneficio, en la mantención de su vida, salud y bienestar". El objetivo de este artículo fue determinar la importancia de la aplicación de la teoría de los sistemas de enfermería, para el abordaje de intervenciones de enfermería en la prevención del bajo peso al nacer desde la Atención Primaria de Salud.Las conclusionesdan luces sobrelas mujeres con diagnóstico de riesgo reproductivo preconcepcional y condiciones de riesgo para tener hijos con bajo peso al nacer, en particular, deben incorporar a su vida diaria autocuidados que les permitan prevenir complicaciones. Las teorías ayudan a adquirir conocimientos que contribuyen a perfeccionar prácticas cotidianas mediante la descripción, explicación, predicción y control de los fenómenos; además facilita a los profesionales autonomía de acción como guía en aspectos prácticos, educativos y de investigación.


Low birth weight is a global concern; programs designed to prevent it depend on the identification of susceptible pregnant women. There is little evidence in the literature about care by the Nursing professional directed to women with risk factors of having children with low birth weight from Primary Health Care. However, there are theories and conceptual models that can be applied to guide interventions. The Theory of Nursing Systems is the one assumed by the authors of this research because they consider it very useful in Public Health, because in the field of personal responsibility for health, it focuses self-care on the initiative of those who they require it, understanding it as "the practice of activities that individuals themselves initiate and develop for their own benefit, in maintaining their life, health and well-being." The goal of this study was to determine the importance of the application of the theory of nursing systems, for the approach of nursing interventions in the prevention of low birth weight from Primary Health Care.The conclusions shed light on the women with a diagnosis of preconception reproductive risk and risk conditions for having children with low birth weight, in particular, should incorporate self-care into their daily lives that allow them to prevent complications. Theories help to acquire knowledge that helps to improve daily practices through the description, explanation, prediction and control of phenomena; it also provides professionals with autonomy of action as a guide in practical, educational and research aspects.


Subject(s)
Humans , Infant, Newborn , Primary Health Care , Nursing Theory , Infant, Low Birth Weight , Self Care
18.
Rev. medica electron ; 43(1): 2748-2758, tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1156772

ABSTRACT

RESUMEN Introducción: la infección urinaria en el embarazo constituye uno de los principales problemas de salud, que influyen de forma directa en el desarrollo del embarazo y el parto. Objetivo: caracterizar las gestantes con infección urinaria, pertenecientes al área de salud del Policlínico Universitario "Ángel Machaco Ameijeiras" de Guanabacoa, La Habana, Cuba, de enero 2019 a enero 2020. Materiales y Métodos: se realizó un estudio descriptivo y de corte transversal en 129 gestantes del área de salud y periodo de tiempo antes definidos. La información se obtuvo de las historias clínicas individuales. Las principales variables a medir fueron: edad materna, germen causal, modificaciones cervicales, y complicaciones prenatales y post natales más frecuentes. Resultados: predominó la infección urinaria en 52 pacientes (40,31 %), el grupo de edades de 26-30 años fue el más representado, con 47 casos (36,43 %), las modificaciones cervicales estuvieron presentes en 35 pacientes (67,30 %) y el germen causal más frecuente fue el staphylococcus ssp en 22 pacientes (42,30 %) y valor P=0,01. La presencia de bajo peso/ crecimiento intrauterino retardado se representó en 18 pacientes (34,61%). Conclusiones: se caracterizó las gestantes incluidas en el estudio, predominó la existencia de infección urinaria y el bajo peso fue la complicación más representada (AU).


SUMMARY Introduction: the urinary infection in pregnancy is one of the main health problems, influencing in a straight way in pregnancy development and childbirth. Objective: to characterize pregnant women with urinary infection belonging to the health are of the University Polyclinic "Ángel Machaco Ameijeiras" of Guanabacoa, La Habana, Cuba, from January 2019 to January 2020. Materials and methods: a descriptive, cross-sectional study was carried out in 129 pregnant women of the aforementioned health area during the period herein declared. The information was gathered from the individual medical records. The main variables measured were: maternal age, causal germ, cervical modifications and more frequent prenatal and postnatal complications. Results: urinary infection predominated in 52 patients (40.31 %); the 26-30 age group was the most represented one, with 47 cases (36.43 %); cervical modifications were present in 35 patients (67.30 %); and the most frequent causal germ was the Staphylococcus ssp., in 22 patients (42.30 %), P value=0.01. Low weight/IUGR was present in 18 patients (34.61 %). Conclusions: pregnant women included in the study were characterized, predominating the existence of urinary infection. Low weight was the most represented complication (AU).


Subject(s)
Humans , Female , Pregnancy , Pregnancy Complications , Urinary Tract Infections/etiology , Vaginal Diseases , Infant, Low Birth Weight , Pregnant Women , Epidemiology, Descriptive , Cross-Sectional Studies , Escherichia coli
19.
Rev. medica electron ; 43(1): 2771-2783, tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1156774

ABSTRACT

RESUMEN Introducción: diversos son los factores mancomunados a un mayor riesgo de recién nacidos con bajo peso al nacer en gestantes. Objetivos: aplicar y validar un índice pronóstico para la estratificación de riesgo de recién nacidos con bajo peso al nacer. Material y métodos: se realizó un estudio observacional de corte longitudinal, prospectivo o de cohortes en gestantes atendidas en el área de salud del municipio de Guanabacoa, en el período comprendido desde el 1º de enero de 2016 hasta el 31 de diciembre del 2019, para aplicar un índice pronóstico de bajo peso al nacer, con elementos clínicos. Mediante la función de regresión logística apreciada se calcularon las probabilidades de bajo peso al nacer en la muestra de estimación, y esa distribución empírica fue fragmentada en terciles para escrutar zonas que permitieran clasificar a las gestantes como de bajo, mediano y alto riesgo de bajo peso. Resultados: el (85,7 %) de las gestantes poseían baja probabilidad de bajo peso al nacer. El 60,4 % de las gestantes estuvieron clasificadas como pacientes con una alta probabilidad de bajo peso al nacer, y la mayoría de los pacientes clasificados de riesgo medio con bajo peso al nacer; 11 pacientes no fueron clasificados adecuadamente por el Índice pronostico. Conclusiones: el índice construido mostró eficacia y robustez adecuadas, siendo útil para realizar pronóstico de bajo peso al nacer en gestantes del área de salud (AU).


SUMMARY Introduction: there are many factors associated to a bigger risk for newborns with low weight at birth. Objective: to apply and to validate a prognostic index for the risk stratification in newborns with low weight at birth. Materials and methods: a cohort or prospective, longitudinal, observational study was carried out in pregnant women attending the health area of Guanabacoa municipality in the period from January 1st 2016 until December 31st 2019 to apply a prognostic index of low weight at birth, with clinical elements. Through the appreciated logistic regression function the possibilities of low weight at birth were calculated in the estimation sample, and that empiric distribution was fragmented in tertils to scrutinize zones allowing classifying pregnant women as low, medium and high risk of low weight births. Results: 85.7% of the pregnant women showed low probability of low birth weight. 60.4% of them was classified as patient with a high probability of low birth weight, and most of the patients classified as of medium risk of low birth weight; 11 patients were not adequately classified by the prognostic index. Conclusions: the conformed index showed suitable efficacy and reliability, being useful to carry out prognosis of low weight at birth in pregnant women of the health area (AU).


Subject(s)
Humans , Prognosis , Severity of Illness Index , Infant, Low Birth Weight , Risk Factors , Risk Index , Longitudinal Studies , Observational Study
20.
Braz. j. med. biol. res ; 54(1): e10120, 2021. tab, graf
Article in English | LILACS | ID: biblio-1153505

ABSTRACT

This study aimed to estimate and compare racial inequality in low birth weight (LBW), preterm birth (PTB), and intrauterine growth restriction (IUGR) in two Brazilian birth cohorts. This was a cross-sectional study nested within two birth cohorts in Ribeirão Preto (RP) and São Luís (SL), whose mothers were interviewed from January to December 2010. In all, 7430 (RP) and 4995 (SL) mothers were interviewed. The maternal skin color was the exposure variable. Associations were adjusted for socioeconomic and biological covariates: maternal education, per capita family income, family economic classification, household head occupation, maternal age, parity, marital status, prenatal care, type of delivery, maternal pre-pregnancy BMI, hypertension, hypertension during pregnancy, and smoking during pregnancy collected from questionnaires applied at birth. Statistical analysis was done with the chi-squared test and logistic regression. In RP, newborns from mothers with black skin color had a higher risk of LBW and IUGR, even after adjusting for socioeconomic and biological variables (P<0.001). In SL, skin color was not a risk factor for LBW (P=0.859), PTB (P=0.220), and IUGR (P=0.062), before or after adjustment for socioeconomic and biological variables. The detection of racial inequality in these perinatal outcomes only in the RP cohort after adjustment for socioeconomic and biological factors may be reflecting the existence of racial discrimination in the RP society. In contrast, the greater miscegenation present in São Luís may be reflecting less racial discrimination of black and brown women in this city.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Socioeconomic Factors , Infant, Low Birth Weight , Continental Population Groups , Premature Birth/ethnology , Health Status Disparities , Brazil/epidemiology , Cesarean Section , Cross-Sectional Studies , Risk Factors
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