Lógica histórica da medicina e a homeopatia / The historical logic of medicine and homeopathy

Este artigo baseia-se na tese de que a teoria homeopática está originalmente orientada por um vitalismo de caráter hermenêutico, isto é, assume que a positividade dos fenômenos com que lida é sempre dependente de uma totalidade compreensiva (totalidade vital), singularizada em cada situação individual e somente acessível por meio das narrativas dos pacientes. O objetivo do estudo foi compreender as relações entre estas concepções vitalistas e o lugar dos procedimentos compreensivo- -interpretativos na propedêutica e terapêutica propostas pela teoria homeopática, as quais podem apontar alternativas para estabelecer as suas bases de validação. Trata-se de um estudo qualitativo, baseado na análise documental de textos canônicos da homeopatia, especialmente a obra de Hahnemann, e entrevistas em profundidade com homeopatas que combinam atividade clínica com pesquisa e docência na área (formadores de opinião). A metodologia foi instruída pela Hermenêutica Filosófica e pela Epistemologia Histórica, sendo o substrato discursivo (escrito e falado) trabalhado de modo não-formalista, buscando-se identificar e interpretar livremente eixos narrativos e núcleos de significado julgados relevantes. A discussão voltou-se fundamentalmente para a recuperação dos principais movimentos históricos de conformação do paradigma vitalista na homeopatia, o cotejamento desse desenvolvimento com a adoção de procedimentos semiológicos de caráter compreensivo-interpretativo e as implicações desse "vitalismo da palavra" para as concepções homeopáticas contemporâneas. O trabalho aponta para a positividade e produtividade do trabalho com a linguagem e as narrativas no âmbito de uma homeopatia entendida como uma "medicina do sujeito", e sugere aprofundamentos na direção hermenêutico- -filosófica como alternativa para o adensamento conceitual e para o aperfeiçoamento dos processos de validação do saber e da prática da homeopatia.

Homeopathic medicine is a socially validated practice, progressively incorporated into the institutional health care scheme, including the public health system. However, the issue of the fundamentals of this therapeutic, of its scientific validation, remains outstanding. In the sense of responding to this demand for validation, there is a need for research methodologies. that allow for accurate investigations, suitable for the concepts of health, illness and therapeutics that are intrinsic to the homeopathic rational. This paper is based on the notion that homeopathic theory is originally guided by a vitalism of hermeneutical character, that. is, it assumes that the positivity of phenomena with which it deals, is always dependent on the comprehensive totality (vital totality), specific to each individual situation and accessible only by means of the patients´ narratives. The study's purpose was to understand the relations between these vitalist concepts and the place of comprehensive-interpretative procedures in the propedeutics and therapeutics proposed by the homeopathic medicine that may point out to alternatives to establish its validation bases. This is qualitative research, based on the documentary analysis of homeopathy canonic texts, especially the work of Hahnemann, and originally n-depth interviews with homeopaths that combine clinic activity and education in the area (opinion makers). The methodology was instructed by Philosophic. Hermeneutics and by Historic Epistemology, and the layer subjacent to the discourse (written and spoken) effected in a non-formal manner, searching for the free identification. And interpretation of the narrative axes and core meanings that were deemed significant. The discussion was basically focused on the recovery of the major historical movements related. To the development of the vitalist paradigm in homeopathy, the comparison of this development with the adoption of semiologic procedures of comprehensive- -interpretative character and the implications of this "vitalism of the word" to the contemporary homeopathic concepts. The paper points out to the positivity and productivity of the work on language and narratives in the domain of a homeopathy understood as "medicine of the subject" and suggests deeper studies in the hermeneutical-philosophical direction as an alternative for the concept densification and for the improvement of validation processes of knowledge and practice of homeopathy.

Intra- and interobserver agreement of histopathological findings in pediatric patients with eosinophilic esophagitis

Abstract Objective: To assess intra- and interobserver agreement among non-expert pathologists in identifying features of the eosinophilic esophagitis histologic scoring system (EoEHSS) in pediatric patients. Patients and methods: The authors used 50 slides from patients (aged 1-15 years; 72% male) with EoE. EoEHSS evaluates eosinophilic inflammation and other features including epithelial basal zone hyperplasia, eosinophilic abscesses, eosinophil surface layering, dilated intercellular spaces, surface epithelial alteration, dyskeratotic epithelial cells, and lamina propria fibrosis. Grade and stage of abnormalities are scored using a 4-point scale (0 normal; 3 maximum change). Four pathologists determined EoEHSS findings on two occasions. Intra- and interobserver agreement was assessed using Kappa (κ) statistics and intra-class correlation coefficients. Results: Intra- and interobserver agreement for the identification of eosinophil counts ≥ 15/high power field (HPF) was excellent, however varied when assessing additional features of the EoEHSS. For the more experienced pathologist, agreement for most EoEHSS items and the composite scores was substantial to excellent. For the less experienced pathologists, intraobserver agreement ranged from absent to substantial for individual features and ranged from moderate to substantial for the composite scores. Conclusion: Most items of the EoEHSS had substantial to excellent reliability when assessed by a pathologist experienced in the diagnosis of EoE but presented lower repeatability among less experienced pathologists. These findings suggest that specific training of pathologists is required for the identification of EoEHSS characteristics beyond eosinophil count, as these features are considered useful in the evaluation of response to treatment and correlation with clinical manifestations and endoscopic findings.

Análisis comparativo de la visualización del canal mandibular mediante tomografía computarizada cone beam en humanos / Comparative analysis of the visualization of the mandibular canal by cone beam computed tomography in humans

RESUMEN: Una de las estructuras de mayor interés en la región maxilofacial es el canal mandibular, donde su preservación optimiza el éxito de los procedimientos clínicos. Por su disposición al interior de la mandíbula, la visualización in vivo requiere el uso de técnicas radiográficas, entre las que destaca el Cone Beam CT (CBCT). El objetivo de este trabajo es comparar la visualización del canal mandibular humano mediante imágenes en CBCT con distintos observadores y programas de radiación. Mediante imágenes generadas con CBCT en mandíbulas secas con distintos programas de adquisición, se obtuvieron cortes coronales en los sectores anterior, medio y posterior del canal mandibular, con un total 240 mediciones, las que incluyeron dos tamaños de voxel y dos dosis de radiación distintos. Cada una de las imágenes fue evaluada por un Cirujano Dentista, Máster en Anatomía y Especialista en radiología Máxilofacial. Se obtuvieron porcentajes de visualización según observador para cada programa de adquisición de imágenes. La prueba de Q de Cochran arrojó diferencias entre los observadores (p0,05). El grado de experticia del observador influye en la visualización y su precisión. A su vez, utilizar un programa de adquisición de imagen con distinto voxel y/o dosis no afecta a la visualización, siendo esta dependiente de la anatomía propia de la estructura. Podría utilizarse un protocolo con menor radiación para el usuario cumpliendo con la premisa ALARA (As Low As Reasonably Achievable).

SUMMARY: One of the structures of greatest interest in the maxillofacial region is the mandibular canal, where its preservation optimizes the success of clinical procedures. Due to its disposition inside the mandible, in vivo visualization requires the use of radiographic techniques, among which the Cone Beam CT (CBCT) stands out. The objective of this work is to compare the visualization of the human mandibular canal by means of CBCT images with different observers and radiation programs. Using images generated with CBCT in dry mandibles with different acquisition programs, coronal slices were obtained in the anterior, middle and posterior sectors of the mandibular canal, with a total of 240 measurements, which included two voxel sizes and two doses different radiation sources. Each of the images was evaluated by a Dentist, an Anatomy Master's degree and a specialist in Oral & Maxillofacial Radiology. Percentages of visualization according to observer were obtained for each image acquisition program. The Cochran Q test yielded differences between the observers (p 0.05). The degree of expertise of the observer influences the visualization and its precision. In turn, using an image acquisition program with a different voxel/radiation dose not affect the visualization, since it depends on the anatomy of the structure itself. A protocol with less radiation could be used in patients complying with the ALARA ("As Low As Reasonably Achievable") premise.

Concordância Interobservador no Diagnóstico Citológico de Atipia Escamosa de Significado Indeterminado Favorecendo Lesão de Alto Grau e de Lesão / Intraepitelial Escamosa de Alto Grau nas Lesões do Colo Uterino Interobserver Agreement in Cytological Diagnosis of Atypical Squamous Cell, Cannot Exclude a High-Grade Lesion and High-Grade Squamous Intraepithelial Lesion in Cervical Lesions / Concordancia Interobservador en el Diagnóstico Citológico de Atipia Escamosa de Significado Indeterminado Favoreciendo Lesión de Alto Grado y Lesión Intraepitelial Escamosa de Alto Grado en Lesiones del Cuello Uterino

Introdução: O exame de Papanicolau é uma importante ferramenta na triagem do carcinoma do colo uterino. O diagnóstico citológico de atipias celulares escamosas de significado indeterminado favorecendo lesão de alto grau (ASC-H) é a categoria de menor concordância interobservador. Objetivo: Avaliar o grau de concordância interobservador para os diagnósticos de ASC-H e de lesões intraepiteliais escamosas de alto grau (LIEAG) em um hospital terciário e avaliar a capacidade do diagnóstico de ASC-H para predizer lesões de maior grau. Método: Foram coletadas lâminas de pacientes atendidas entre 2007 e 2015 no Serviço de Anatomia Patológica do hospital, com diagnósticos originais de ASC-H ou LIEAG realizados pelo mesmo patologista, colposcopia e biópsia, quando indicadas, pelo mesmo ginecologista. Essas citologias foram posteriormente revisadas por outros dois patologistas separadamente e às cegas. Ambos tiveram acesso a dados sobre idade no momento do diagnóstico para reproduzir o diagnóstico da prática clínica. Resultados: Houve 65,1% de lâminas listadas com ASC-H e 34,9% com LIEAG. As duas revisões concordaram concomitantemente com o diagnóstico original em 54,7%. Os índices kappa para os dois diagnósticos e somente para ASC-H foram, respectivamente, 0,46 e 0,49 (concordâncias moderadas). Das lâminas originalmente interpretadas como ASC-H, 68,3% resultaram em lesões de maior grau na histologia. Conclusão: Os dados mostraram uma concordância moderada entre os patologistas para o diagnóstico de ASC-H. É importante destacar que o diagnóstico de ASC-H correspondeu à lesão de maior grau de malignidade na histologia, demonstrando que essas lesões devem ser seguidas clinicamente como LIEAG

Introduction: The Papanicolaou test is an important screening exam for cervical carcinoma. The cytological diagnosis of undetermined atypical squamous cells favoring high-grade lesion (ASC-H) is the category with the least interobserver concurrence. Objective: Evaluate the interobserver concurrence for the ASC-H and high-grade squamous intraepithelial lesions (HSIL) categories at a teaching hospital and to estimate ASC-H's capacity to predict higher grade lesions. Method: Smears from patients admitted from 2007 to 2015 whose original diagnosis was made by one pathologist, in addition to colposcopy and biopsy, when indicated, made by one gynecologist were collected in the Pathologic Anatomy Service of the hospital. The cytology was reviewed by two other pathologists separately and blindly. Both reviewers had access to data about age at the moment of the diagnosis in order to reproduce the clinical diagnosis. Results: There were 65.1% smears considered as ASC-H and 34.9%, as HSIL. The reviews concurred simultaneously with the original diagnosis in 54.7% of the cases. The kappa indexes for both categories and only for ASC-H were, respectively, 0.46 and 0.49 (moderate concurrence). 68.3% of the smears primarily described as ASC-H resulted in higher grade lesions in histology. Conclusion: The data showed a moderate concurrence between the pathologists for the ASC-H's diagnosis. It is important to highlight that ASC-H matched with higher grade lesions at the histology, needing follow-up as HSIL

Introducción: La prueba de Papanicolaou es un importante examen de detección del carcinoma del cuello uterino. El diagnostico citológico de las células escamosas atípicas, no se descarta una lesión de grado alto (ASC-H) es la categoría de menor acuerdo interobservador. Objetivo: Los objetivos de este estudio fueron evaluar el grado de concordancia interobservador para los diagnósticos de atipias escamosas de significado indeterminado favoreciendo lesión de alto grado (ASC-H) y de lesiones intraepiteliales escamosas de alto grado (LIEAG) en un hospital terciario de Curitiba (PR) y evaluar la capacidad del diagnóstico de ASC-H de predecir las lesiones de mayor grado. Método: Se recogieron del Servicio de Anatomía Patológica del hospital las láminas de pacientes atendidas entre 2007 y 2015, con diagnósticos originales de ASC-H o LIEAG realizados por el mismo patólogo y colposcopia y biopsia, cuando indicadas, por el mismo ginecólogo. Esas citologías fueron revisadas después por otros dos patólogos separadamente y a ciegas. Ambos tuvieron acceso a datos sobre edad en el momento del diagnóstico para reproducir el diagnóstico de la práctica clínica. Resultados: Hubo el 65,1% de las láminas señaladas con ASC-H y el 34,9%, con LIEAG. Las revisiones concordaron concomitantemente con el diagnóstico original en el 54,7%. Los índices kappa para los dos diagnósticos y solamente para ASC-H fueron, respectivamente, 0,46 y 0,49 (concordancias moderadas). De las láminas originalmente interpretadas como ASC-H, 68,3% resultaron en lesiones de mayor grado en la histología. Conclusión: Hubo una concordancia moderada entre los patólogos para la categoría ASC-H. Se destaca también la correspondencia de ASC-H con lesiones de mayor grado en la histología, lo que dirige su seguimiento clínico como LIEAG

Diagnostic consistency for observing endodontic files in digital radiographs displayed on different electronic devices / 中华口腔医学杂志

Objectives: To evaluate the diagnostic consistency of working lengths by observing endodontic files in root canals and periapical subtle structures in digital intraoral radiographs presented in two smartphones, a tablet and a laptop computer. Methods: A dried human skull embedded in an acrylic compound was used for exposing radiographs of the upper and lower second premolars and first molars with two endodontic files (Kerr files size 10 and 15) positioned to the full length of the roots or 1.5 mm short of apexes. A total of 100 radiographs were taken for each of the file sizes. Five observers were asked to assess all the 200 digital radiographs according to a 5-category scale in smartphone A (HUAWEI P9 Plus), smartphjone B (Apple iPhone 7), tablet (Apple iPad 2018) and laptop computer (Lenovo Thinkpad E480), respectively. The gold standard for receiver operating characteristic curve (ROC) analysis was determined with the endodontic Kerr file size 20. A total of 150 roots with files were radiographed, 75 of which with files reaching the radiographic apexes of the respective roots and 75 of which with files 1.5 mm short of the radiographic apexes for each endodontic file size. Results from ROC analysis was analyzed with one-way ANOVA and independent sample t test. Results: For the Kerr file size 10, the area under the ROC curve for laptop, tablet and two smartphones were 0.891±0.037, 0.869±0.037, 0.870±0.017 and 0.849±0.037, while for the Kerr file size 15 the ROC values were 0.957±0.02, 0.961±0.02, 0.961±0.01 and 0.961±0.02, respectively. There were no significant differences for diagnostic accuracy for observing endodontic file positions among digital radiographs presented in the two smartphones, one tablet and one laptop devices (endodontic file size 10: F=1.39, P=0.281; endodontic file size 15: F=0.05, P=0.985). A significant difference was found in the diagnostic accuracy of endodontic file positions between size 10 and 15 files in different display devices (t=-10.65, P<0.001). Conclusions: There was a high diagnostic consistency in the determination of working length and periapical subtle structures of roots by observing digital radiographs displayed on smartphones, tablet and laptop computer.

Inter-rater reliability of a composite health promotion scoring system developed in Singapore

INTRODUCTION@#In view of the important role of the environment in improving population health, implementation of health promotion programmes is recommended in living and working environments. Assessing the prevalence of such community health-promoting practices is important to identify gaps and make continuous and tangible improvements to health-promoting environments. We aimed to evaluate the inter-rater reliability of a composite scorecard used to assess the prevalence of community health-promoting practices in Singapore.@*METHODS@#Inter-rater reliability for the use of the composite health promotion scorecards was evaluated in eight residential zones in the western region of Singapore. The assessment involved three raters, and each zone was evaluated by two raters. Health-promoting practices in residential zones were assessed based on 44 measurable elements under five domains - community support and resources, healthy behaviours, chronic conditions, mental health and common medical emergencies - in the composite scorecard using weighted kappa. The strength of agreement was determined based on Landis and Koch's classification method.@*RESULTS@#A high degree of agreement (almost perfect-to-perfect) was observed between both raters for the measurable elements from most domains and subdomains. An exception was observed for the community support and resources domain, where there was a lower degree of agreement between the raters for a few elements.@*CONCLUSION@#The composite scorecard demonstrated a high degree of reliability and yielded similar scores for the same residential zone, even when used by different raters.

Diagnosing Septate Uterus Using Three-Dimensional Ultrasound Using Three Different Classifications: An Interobserver and Intraobserver Agreement Study / Diagnóstico de útero septado com ecografia tridimensional usando três classificações diferentes: Um estudo de concordância interobservador e intraobservador

Abstract Objective Currently, there are up to three different classifications for diagnosing septate uterus. The interobserver agreement among them has been poorly assessed. To assess the interobserver agreement of nonexpert sonographers for classifying septate uterus using the European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy (ESHRE/ESGE), American Society for Reproductive Medicine (ASRM), and Congenital Uterine Malformations by Experts (CUME) classifications. Methods A total of 50 three-dimensional (3D) volumes of a nonconsecutive series of women with suspected uterine malformation were used. Two nonexpert examiners evaluated a single 3D volume of the uterus of each woman, blinded to each other. The following measurements were performed: indentation depth, indentation angle, uterine fundal wall thickness, external fundal indentation, and indentation-to-wall-thickness (I:WT) ratio. Each observer had to assign a diagnosis in each case, according to the three classification systems (ESHRE/ESGE, ASRM, and CUME). The interobserver agreement regarding the ESHRE/ESGE, ASRM, and CUME classifications was assessed using the Cohen weighted kappa index (k). Agreement regarding the three classifications (ASRM versus ESHRE/ESGE, ASRM versus CUME, ESHRE/ESGE versus CUME) was also assessed. Results The interobserver agreement between the 2 nonexpert examiners was good for the ESHRE/ESGE (k = 0.74; 95% confidence interval [CI]: 0.55-0.92) and very good for the ASRM and CUME classification systems (k = 0.95; 95%CI: 0.86-1.00; and k = 0.91; 95%CI: 0.79-1.00, respectively). Agreement between the ESHRE/ESGE and ASRM classifications was moderate for both examiners. Agreement between the ESHRE/ESGE and CUME classifications was moderate for examiner 1 and good for examiner 2. Agreement between the ASRM and CUME classifications was good for both examiners. Conclusion The three classifications have good (ESHRE/ESGE) or very good (ASRM and CUME) interobserver agreement. Agreement between the ASRM and CUME classifications was higher than that for the ESHRE/ESGE and ASRM and ESHRE/ESGE and CUME classifications.

Resumo Objetivo Atualmente, existem até três classificações diferentes para o diagnóstico de útero septado. A concordância interobservador entre eles tem sido pouco avaliada. Avaliar a concordância interobservador de ecografistas não especialistas para classificar úteros septados usando as classificações European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy (ESHRE/ESGE, na sigla em inglês), American Society for Reproductive Medicine (ASRM, na sigla em inglês) e Congenital Uterine Malformations by Experts (CUME, na sigla em inglês). Métodos Foram utilizados50volumes tridimensionais (3D)deuma série não consecutiva de mulheres com suspeita de malformação uterina. Dois examinadores não especialistas avaliaram um único volume 3D do útero de cada mulher, mutuamente cegos. As seguintes medidas foram aferidas: profundidade de indentação, ângulo de indentação, espessura da parede do fundo uterino, indentação externa do fundo e relação entre indentação e a espessura da parede (I:WT, na sigla em inglês). Cada observador teve que atribuir um diagnóstico em cada caso, de acordo com os três sistemas de classificação (ESHRE/ESGE, ASRM e CUME). A concordância interobservador em relação às classificações ESHRE/ESGE, ASRM e CUME foi avaliada usando o índice kappa ponderado de Cohen (k). A concordância em relação às três classificações (ASRM versus ESHRE/ESGE, ASRM versus CUME e ESHRE/ ESGE versus CUME) também foi avaliada. Resultados A concordância interobservador entre os 2 examinadores não especialistas foi boa para a classificação ESHRE/ESGE (k = 0,74, intervalo de confiança [IC] 95%: 0,55-0,92) e muito boa para os sistemas de classificação ASRM e CUME (k = 0,95; IC 95%: 0,86-1,00; e k = 0,91; IC95%: 0,79-1,00, respectivamente). A concordância entre as classificações ESHRE/ESGE e ASRM foi moderada para ambos os examinadores. A concordância entre as classificações ESHRE/ESGE e CUME foi moderada para o examinador 1 e boa para o examinador 2. A concordância entre as classificações ASRM e CUME foi boa para ambos os examinadores. Conclusão As três classificações apresentam concordância interobservador boa (ESHRE/ESGE) ou muito boa (ASRM e CUME). A concordância entre as classificações ASRM e CUME foi maior do que entre as classificações ESHRE/ESGE e ASRM e ESHRE/ESGE e CUME.

Detección de tornillos prominentes en la articulación radiocarpiana mediante la proyección tangencial del escafoides dorsal / Detection of protruding screws in the radiocarpal joint using the "scaphoid skyline view"

INTRODUCCIÓN: Una de las complicaciones de la osteosíntesis retrógrada del escafoides es la protrusión del tornillo en la articulación radiocarpiana, dada la limitada visualización intraoperatoria del polo proximal del escafoides con las proyecciones tradicionales. OBJETIVO: Evaluar la capacidad de una nueva proyección radiológica, la proyección "tangencial del escafoides dorsal", o TED, para identificar tornillos prominentes radiocarpianos durante la osteosíntesis retrógrada del escafoides con tornillos canulados. MATERIALES Y MÉTODOS: Estudio cadavérico en muñecas frescas congeladas. Se introdujo en el escafoides un tornillo canulado con técnica retrógrada estándar. La proyección TED fue evaluada en 5 muñecas, con angulaciones del antebrazo de 15°, 30° y 45° para definir la mejor visualización del polo proximal del escafoides y del tornillo. Se comparó la capacidad para identificar la prominencia del tornillo en el polo proximal de la proyección TED de 30° con 5 proyecciones tradicionales de escafoides en 9 muñecas. El tornillo se posicionó a nivel de la superficie del escafoides, y luego se avanzó a intervalos de 0,5 mm bajo visualización directa por artrotomía dorsal. Tras cada intervalo, se repitieron todas las proyecciones para determinar su capacidad de detectar tornillos prominentes en el escafoides. RESULTADOS: La mejor visualización del polo proximal del escafoides se logró con la proyección TED de 30°. Al comparar la proyección TED de 30° y las tradicionales, con la TED se logró identificar tornillos prominentes a 0,8 mm promedio, seguida por la proyección posteroanterior con cubitalización y extensión a 1.3 mm (p » 0.014), con una alta precisión y correlación interobservador de estas proyecciones. CONCLUSIÓN: La proyección TED demostró ser la más sensible para detectar tornillos prominentes en la articulación radiocarpiana. Su uso rutinario podría evitar complicaciones durante la osteosíntesis.

INTRODUCTION: One of the complications of the retrograde percutaneous scaphoid fixation is the protrusion of the screw in the radiocarpal joint due to the limited intraoperative visualization of the proximal pole of the scaphoid with the traditional radiographic views. OBJETIVE: To evaluate the sensitivity of a novel radiographic view (the skyline scaphoid view, SSV) to detect screws protruding in the radiocarpal joint during the retrograde fixation of the scaphoid. MATERIALS AND METHODS: We studied nine cadaverous fresh frozen wrists. A retrograde cannulated screw was inserted in the scaphoid. To validate the SSV, 5 wrists were studied, comparing 3 forearm angulations (15°, 30° and 45°) to get the best visualization of the proximal pole and screw. We compared the ability to identify the protrusion of the screw in the proximal pole of the 30° SSV with that of 5 standard scaphoid radiographic views in 9 wrists. The screw was positioned at the level of the surface of the scaphoid, and was sequentially protruded in 0.5 mm increments, with direct visualization of its tip through a dorsal capsulotomy. After each increment, all views were repeated to determine if they were able to detect screws projecting from the scaphoid. RESULTS: The best visualization of the proximal pole of the scaphoid was found with the 30° SSV. In the comparison of the 30° SSV and the standard views, with the SSV we were able to identify the protrusion of the screws at an average of 0.8 mm, followed by the posterior-anterior view with ulnar deviation and extension at 1.3 mm (p » 0.014), with high precision and interobserver agreement regarding these views. CONCLUSION: The SSV was the most sensitive view to detect protruding screws in the proximal pole of the scaphoid. Its routine use could avoid complications during osteosynthesis.

Confiabilidade da análise de processo para o desempenho da tarefa de levantar-se do solo em idosos / Intra e inter reliability of supine-to-stand task performance in older adults

A tarefa de levantar-se do solo a partir do decúbito dorsal (STS) tem apresentado recursos avaliativos complementares, em termos de julgamento do desempenho motor, físico e funcional em idosos por meio de medidas quantitativas e qualitativas. Especificamente, em medidas de processo (qualitativas) há sete protocolos que categorizam o desempenho do STS em idosos. Objetivo: Determinar o nível de confiabilidade intra e entre avaliadores da análise de processo do STS em idosos, segundo protocolo adaptado de Manini et al. Métodos: 25 idosos (12 mulheres) realizaram a tarefa de levantar-se do solo a partir do decúbito dorsal sem auxílio. Dois codificadores de vídeo, estudantes de graduação no nível superior de educação - tempo de experiência > 2 anos em Educação Física e ± 6 meses de uso do protocolo classificaram o desempenho dos idosos de acordo com o protocolo. A confiabilidade intra-avaliador e entre avaliadores foi considerada moderada (K = 0,533; p = 0,001; K = 0,466; p = 0,001) e substancial para a medida intra-avaliador 2 (K = 0,736; p = 0,001). O nível de confiabilidade intra e entreavaliadores do STS segundo o protocolo adaptado de Manini foi considerado moderado para sujeitos idosos. (AU)

The Supine-To-Stand task (STS) has presented complementary assessment resources, in terms of motor, physical and functional assessment in the elderly through quantitative and qualitative measures. Specifically, in process measures (qualitative) seven protocols categorize the performance of STS in the elderly. Objective: To determine the level of reliability within and between evaluators of the STS process analysis in the elderly, according to a protocol adapted from Manini et al. Methods: 25 elderly (12 female) performed the task of rising from the ground from the supine position without assistance. Two video encoders, graduate students at the higher education level - time of experience >2 years in Physical Education and ± 6 months in use of the protocol classified the performance of the elderly according to this protocol. Intra-rater and between rater reliability was considered moderate (K = 0.533; p = 0.001; K = 0.466; p = 0.001) and substantial for intra-rater 2 (K = 0.736; p = 0.001). The level of intra- and inter-rater reliability of the STS according to the adapted protocol of Manini was considered moderate for elderly subjects. (AU)

Comparison of methods for evaluating upper limb strength by hand-held dynamometry / Comparação entre métodos na avaliação de dinamometria hand-held para músculos dos membros superiores / Comparación entre métodos en la evaluación de dinamometría hand-held para músculos de los miembros superiores

ABSTRACT Introduction The upper limbs are segments of the human body responsible for primary activities of daily life, and the muscles are essential structures for performing these activities. There have been few studies on intra- and inter-examiner reliability of the hand-held dynamometer (HHD) in healthy subjects, and none have been published that compare dynamometric evaluation methods in the main muscles in this segment. Objective Evaluate intra-examiner and inter-examiner assessment reliability of the hand-held dynamometry of upper limb muscles in healthy individuals, as well as comparing the assessment reliability between fixed and non-fixed methods. Methods Healthy subjects aged over 18 years were recruited for the study. The isometric contraction for ten muscle groups of the dominant upper limb was tested. For the fixed method, we used a system of suction cups, connected to the HHD by an inelastic belt. For the non-fixed method, the examiner supported the device by hand. The isometric contraction was sustained for three seconds. Each measurement was repeated three times, considering the highest value obtained. The reliability was calculated using the intraclass correlation coefficient (ICC). The dispersion between measurements was expressed by a Bland-Altman plot. Results The sample consisted of 25 volunteers, all right-handed. The intra-examiner ICC was 0.89-0.99 for the non-fixed method, and 0.43 to 0.85 for the fixed method. Inter-examiner reliability showed equivalent behavior. This study showed that evaluation of upper limb muscle strength using an isometric dynamometer has excellent intra-examiner and inter-examiner reliability. The supine position was chosen due to the need to propose a feasible protocol for clinical practice that could be replicated for the majority of publics and in different environments. The non-fixed method showed better reliability overall, demonstrating the feasibility of this tool without the need for adaptations, additional devices, or increased operating costs for this evaluation. Conclusion Comparison between the fixed and non-fixed HHD methods demonstrated superiority of the non-fixed method in terms of reliability. Level of evidence II; Investigation of a diagnostic exam - Development of diagnostic criteria with consecutive patients.

RESUMO Introdução Os membros superiores são segmentos do corpo humano responsáveis por atividades primordiais do nosso cotidiano, e os músculos são estruturas imprescindíveis para isso. Ainda são escassos na literatura os estudos sobre a confiabilidade intra e interexaminadores da dinamometria Hand-Held em indivíduos saudáveis, sendo inédita a comparação entre os métodos de avaliação da dinamometria nos principais músculos desse segmento. Objetivo Avaliar a confiabilidade da avaliação intraexaminador e interexaminador da dinamometria manual de músculos do membro superior em indivíduos saudáveis, bem como comparar a confiabilidade da avaliação entre métodos fixos e não fixos. Métodos Foram recrutados indivíduos saudáveis, maiores de 18 anos. A contração isométrica para dez grupos musculares do membro superior dominante foi testada. Para o método fixado, foi empregado um sistema de ventosas conectado ao Dinamomêtro Hand-Held (DHH) por um cinto inelástico. No método não fixado, o examinador apoiou o aparelho com a mão. A contração isométrica foi sustentada por três segundos. Cada medida foi repetida três vezes, considerando o maior valor obtido. A confiabilidade foi calculada através do coeficiente de correlação intraclasse (CCI). A dispersão entre as medidas foi expressa pelo diagrama de Bland-Altman. Resultados A amostra foi composta por 25 voluntários, todos destros. O coeficiente de correlação intraclasse (CCI) dos intraexaminadores para método não fixado foi de 0,89 a 0,99 e, para o método fixado, situou-se entre 0,43 e 0,85. A confiabilidade interexaminadores teve comportamento equivalente. O presente estudo demonstrou que a avaliação da força dos músculos dos MMSS com dinamômetro isométrico apresenta excelente confiabilidade tanto intra como interexaminadores. A escolha do posicionamento em supino vem da necessidade de propor um protocolo factível na prática clínica, replicável para a maioria dos públicos e em ambientes diversos. O fato de o método não fixado demonstrar maior confiabilidade, em geral, expõe a viabilidade do uso dessa ferramenta sem necessidade de adaptações, dispositivos adicionais ou aumento do custo operacional nessa avaliação. Conclusão A comparação entre os métodos fixados e os não fixados da dinamometria Hand-Held demonstrou superioridade do método não fixado quanto à confiabilidade. Nível de evidência II; Estudos diagnósticos - Investigação de um exame para diagnóstico - Desenvolvimento de critérios diagnósticos com pacientes consecutivos.

RESUMEN Introducción Los miembros superiores son segmentos del cuerpo humano responsables de las actividades primordiales de nuestro cotidiano, y los músculos son estructuras imprescindibles para eso. Aún son escasos los estudios sobre la confiabilidad intra e interexaminadores de la dinamometría Hand-Held en individuos saludables, siendo inédita la comparación entre los métodos de evaluación de la dinamometría en los músculos principales de ese segmento. Objetivos Evaluar la confiabilidad de la evaluación intraexaminador e interexaminador de la dinamometría manual de músculos del miembro superior en individuos saludables, bien como comparar la confiabilidad der la evaluación entre métodos fijos y no fijos. Métodos Se reclutaron individuos saludables, mayores de 18 años. Se probó la contracción isométrica para diez grupos musculares del miembro superior dominante. Para el método fijado, se utilizó un sistema de ventosas, conectado al Dinamómetro Hand-Held (DHH) a través de un cinturón inelástico. En el método no fijado, el examinador apoyó el aparato con la mano. La contracción isométrica fue sustentada por tres segundos. Cada medición fue repetida tres veces, considerando el valor más alto obtenido. La confiabilidad fue calculada a través del coeficiente de correlación intraclase (CCI). La dispersión entre las mediciones se expresó por el diagrama de Bland-Altman. Resultados La muestra fue compuesta por 25 voluntarios, todos diestros. El coeficiente de correlación intraclase (CCI) de los intraexaminadores para método no fijado fue de 0,89 a 0,99 y, para el método fijado fue entre 0,43 y 0,85. La confiabilidad intraexaminadores tuvo comportamiento equivalente. El presente estudio demostró que la evaluación de la fuerza de los músculos de los MMSS con un dinamómetro isométrico presenta excelente confiabilidad tanto intra como interexaminadores. La elección del posicionamiento en supino viene de la necesidad de proponer un protocolo factible en la práctica clínica, replicable para la mayoría de los públicos y en ambientes diversos. El hecho de que el método no fijado demuestre mayor confiabilidad, en general, expone la viabilidad del uso de esa herramienta sin necesidad de adaptaciones, dispositivos adicionales o aumento del costo operacional, en esa evaluación. Conclusión La comparación entre los métodos fijados y no fijados de la dinamometría Hand-Held demostró superioridad del método no fijado cuanto a la confiabilidad. Nivel de evidencia II; Estudios diagnósticos - Investigación de un examen para diagnóstico - Desarrollo de criterios diagnósticos con pacientes consecutivos.

Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population

OBJECTIVE: To determine the correlation between the two tomographic classifications for coronavirus disease (COVID-19), COVID-19 Reporting and Data System (CORADS) and Radiological Society of North America Expert Consensus Statement on Reporting Chest Computed Tomography (CT) Findings Related to COVID-19 (RSNA), in the Brazilian population and to assess the agreement between reviewers with different experience levels. METHODS: Chest CT images of patients with reverse transcriptase-polymerase chain reaction (RT-PCR)-positive COVID-19 were categorized according to the CORADS and RSNA classifications by radiologists with different levels of experience and who were initially unaware of the RT-PCR results. The inter- and intra-observer concordances for each of the classifications were calculated, as were the concordances between classifications. RESULTS: A total of 100 patients were included in this study. The RSNA classification showed an almost perfect inter-observer agreement between reviewers with similar experience levels, with a kappa coefficient of 0.892 (95% confidence interval [CI], 0.788-0.995). CORADS showed substantial agreement among reviewers with similar experience levels, with a kappa coefficient of 0.642 (95% CI, 0.491-0.793). There was inter-observer variation when comparing less experienced reviewers with more experienced reviewers, with the highest kappa coefficient of 0.396 (95% CI, 0.255-0.588). There was a significant correlation between both classifications, with a Kendall coefficient of 0.899 (p<0.001) and substantial intra-observer agreement for both classifications. CONCLUSION: The RSNA and CORADS classifications showed excellent inter-observer agreement for reviewers with the same level of experience, although the agreement between less experience reviewers and the reviewer with the most experience was only reasonable. Combined analysis of both classifications with the first RT-PCR results did not reveal any false-negative results for detecting COVID-19 in patients.

Concordância interobservadores em um checklist de cuidados em terapia nutricional enteral / Concordancia interobservadores en una checklist de cuidados en terapia nutricional enteral / Interobserver agreement in a checklist of care in enteral nutrition therapy

Resumo Objetivo Avaliar a concordância interobservadores na aplicação um checklist de cuidados em Terapia Nutricional Enteral (TNE). Métodos Estudo de confiabilidade que precedeu um ensaio clínico (NCT03497221), realizado em hospital universitário do sul do Brasil (junho e julho de 2017). Checklist de 25 itens relacionado aos cuidados em TNE foi realizado por uma enfermeira (Padrão de Referência) e por nove Assistentes de Pesquisa (AP). As avaliações foram feitas concomitantemente e de modo independente. A concordância foi testada utilizando-se o Statistical Package for the Social Sciences versão 21.0. Valores de Kappa (k) foram considerados como concordância entre: pobre (0 a 0,19); relativa (0,20 a 0,39); moderada (0,40 a 0,59); substancial (0,60 e 0,79); quase perfeita (0,80 a 0,99); e perfeita (1). O estudo foi aprovado pelo Comitê de Ética da Instituição (nº 16-0534). Resultados Foram realizadas 351 observações em duplicata, sendo o menor número de observações foi com a AP 5 (n=35) e o maior com a AP 8 (n=45). Foram avaliados itens relacionados a TNE em três blocos: identificação dos frascos de infusões e bomba de infusão; materiais de apoio para administração da terapia; e cuidados ao paciente em uso de TNE. Houve concordância quase perfeita ou perfeita em todos os pares de observação, com o menor Kappa para AP 6 (k=0,890; IC95%=0.86, 0.92) e o maior para AP 3 (k=0,965; IC95%=0.93, 0.99). Conclusão A concordância interobservadores ao aplicar um checklist contendo 25 itens foi excelente, o que minimiza a ocorrência de viés de aferição nas etapas subsequentes.

Resumen Objetivo Evaluar la concordancia interobservadores en la aplicación de una checklist de cuidados en terapia nutricional enteral (TNE). Métodos Estudio de fiabilidad que precedió un ensayo clínico (NCT03497221), realizado en un hospital universitario de la región Sur de Brasil (junio y julio de 2017). Una checklist de 25 ítems relacionados con los cuidados en TNE fue realizada por una enfermera (Estándar de Referencia) y por nueve Asistentes de Investigación (AI). Las evaluaciones fueron llevadas a cabo simultánea e independientemente. La concordancia se comprobó utilizando el Statistical Package for the Social Sciences versión 21.0. Los valores de Kappa (k) se consideraron como concordancia entre: pobre (0 a 0,19); relativa (0,20 a 0,39); moderada (0,40 a 0,59); considerable (0,60 a 0,79); casi perfecta (0,80 a 0,99); y perfecta (1). El estudio fue aprobado por el Comité de Ética de la institución (n.° 16-0534). Resultados Se realizaron 351 observaciones duplicadas, de las cuales el menor número de observaciones fue de la AI 5 (n=35) y el mayor de la AI 8 (n=45). Se evaluaron ítems relacionados con la TNE en tres grupos: identificación de los frascos de infusiones y bomba de infusión, material de apoyo para la administración de la terapia y cuidados del paciente en uso de TNE. Se observó concordancia casi perfecta o perfecta en todos los pares de observación, con el menor Kappa de la AI 6 (k=0,890; IC95 %=0.86, 0.92) y el mayor de la AI 3 (k=0,965; IC95 %=0.93, 0.99). Conclusión La concordancia interobservadores al aplicar una checklist de 25 ítems fue excelente, lo que minimiza la ocurrencia de sesgo de medición en las etapas subsiguientes.

Abstract Objective To assess interobserver agreement in the application of a checklist of care in enteral nutritional therapy (ENT). Methods This is a reliability study that preceded a clinical trial (NCT03497221), carried out at a university hospital in southern Brazil (June and July 2017). A checklist of 25 items related to care in ENT was performed by a nurse (reference standard) and nine research assistants (RA). Assessments were carried out concurrently and independently. Agreement was tested using the Statistical Package for the Social Sciences, version 21.0. Kappa values (k) were considered as poor (0 to 0.19), relative (0.20 to 0.39), moderate (0.40 to 0.59), substantial (0.60 and 0.79), almost perfect (0.80 to 0.99), and perfect (1). The study was approved by an Institutional Review Board (number 16-0534). Results Three hundred fifty-one observations were made in duplicate; the lowest number of observations was with RA, 5 (n = 35) and the highest with RA, 8 (n = 45). Items related to ENT were assessed in three blocks: identification of infusion bottles and infusion pump; support materials for administering the therapy; care for patients using ENT. There was almost perfect or perfect agreement in all observation pairs, with lowest Kappa for RA 6 (k = 0.890; 95% CI = 0.86, 0.92) and the highest for RA 3 (k = 0.965; 95% CI = 0.93, 0.99). Conclusion Interobserver agreement, when applying a checklist containing 25 items, was excellent, which minimizes the occurrence of measurement bias in subsequent steps.

Maximum phonation time in the pulmonary function assessment / Tempo máximo de fonação para avaliação da função pulmonar

ABSTRACT Purpose: to evaluate the reliability of the maximum phonation time (MPT) and Vital Capacity intra and inter-examiner, by means of the single-breath counting test (CT) and the sustained /a/ phoneme, and the slow vital capacity (SVC). Methods: a reliability study carried out in three groups of healthy individuals, each group with 30 volunteers, allocated according to age. SVC was measured using a spirometer, while the MPT was assessed by the phoneme /a/ and CT. The data were analyzed using SPSS version 20.0. Initially, descriptive statistics were used and for data reliability, the intraclass correlation coefficient (ICC). Results: the Intraclass Correlation Coefficients (ICC) were considered excellent, with significant results above 0.92 for SVC and greater than 0.79 for CT and phoneme /a/. Regarding the inter-examiner evaluation, the ICCs were also significant for both SVC with values greater than 0.96, and for CT and the phoneme /a/ with values greater than 0.85. The error inherent in the technique was assessed using the standard error of the measurement for intra and inter-examiner analyses with values ranging from 1.79 to 3.29 for phoneme /a/, 3.20 to 6.58 for CT and 65, 05 to 206.73 for SVCml. Conclusion: phonation techniques with the phoneme /a/ and CT, as well as SVC, have an excellent reliability, due to intra and inter-examiner agreement measures.

RESUMO Objetivo: avaliar a concordância do tempo máximo de fonação (TMF) com a Capacidade Vital, intra e interexaminador, por meio da técnica de contagem numérica em uma única respiração (TC) e do fonema /a/ sustentado e da capacidade vital lenta (CVL). Métodos: trata-se de um estudo de concordância realizado em três grupos de indivíduos saudáveis, cada grupo com 30 voluntários, alocados de acordo a idade. A CVL foi mensurada por meio do espirômetro, enquanto o TMF foi avaliado pela emissão do fonema/a/ e da TC. Os dados foram analisados pelo programa SPSS versão 20.0. Inicialmente utilizou-se estatística descritiva e para concordância dos dados foi utilizado o coeficiente de correlação intraclasse (CCI). Resultados: os Coeficientes de Correlação Intraclasse (CCI) intraexaminadores foram considerados excelentes, com resultados significantes acima de 0,92 para a CVL e maiores que 0.79 para a TC e fonema/a/. Em relação à avaliação interexaminadores, os CCIs também foram significantes tanto para a CVL com valores maiores que 0,96 quanto para a TC e o fonema/a/ com valores maiores que 0,85. O erro inerente a técnica foi avaliada por meio do erro padrão da medida para as analises intra e interexaminadores com valores que variaram de 1,79 a 3,29 para fonema/a/, 3,20 a 6,58 para TC e 65,05 a 206,73 para CVLml. Conclusão: as técnicas de fonação com o fonema /a/ e TC, assim como a CVL, demonstraram uma excelente concordância intra e interexaminadores.

Reproducibility Analysis of Iodine Concentrations of Abdominal Parenchymal Organs Based on Spectral CT / 中国医学科学院学报

Objective To investigate the intra-and inter-observer reproducibility of iodine concentrations of abdominal parenchymal organs based on spectral CT.Methods The water-free iodine images of the venous phase were retrospectively obtained from 50 patients with abdominal dynamic spectral CT scans.The iodine concentrations were measured in the left,right and caudate lobes of liver,spleen,pancreas and bilateral kidneys.Intraclass correlation coefficient(ICC)and Bland-Altman plot were employed to analyze the intra-and inter-observer reproducibility.Results The intra-observer ICCs of the left,right and caudate lobes of liver,spleen,pancreas,and left and right kidneys were 0.938(0.894,0.965),0.932(0.884,0.961),0.939(0.895,0.965),0.947(0.909,0.970),0.912(0.851,0.949),0.946(0.906,0.969)and 0.907(0.842,0.946),which indicated good intra-observer reproducibility.The inter-observer ICCs of the left,right and caudate lobes of liver,spleen,pancreas,and left and right kidneys were 0.947(0.909,0.970),0.927(0.875,0.958),0.943(0.902,0.968),0.956(0.924,0.975),0.934(0.887,0.962),0.927(0.875,0.958)and 0.892(0.818,0.937),which indicated good inter-observer reproducibility.Bland-Altman plots presented that more than 95% points of the intra-observer differences located within 95% CI of limits of agreement for the caudate lobe of liver,spleen,pancreas and bilateral kidneys,which was same as inter-observer differences of the caudate lobe of liver,spleen and right kidney.Conclusion The iodine concentration measurement based on the spectral CT presented good intra-and inter-observer reproducibility for the caudate lobe of liver and spleen.

Construcción y validación de un instrumento para medir conocimientos de madres y cuidadores sobre alimentación complementaria de infantes / Construction and validation of an instrument to measure knowledge of mothers and caregivers on complementary feeding of infants

INTRODUCCIÓN: La nutrición adecuada durante los primeros dos años de vida es fundamental para el desarrollo pleno del potencial del ser humano. La introducción inadecuada, precoz o tardía de la alimentación complementaria trae consecuencias a corto y largo plazo. La alimentación complementaria depende en gran medida de los conocimientos del cuidador que en los países de Latinoamérica generalmente es la madre. OBJETIVO: construir y validar un instrumento para medir los conocimientos maternos y de cuidadores sobre alimentación complementaria. SUJETOS Y MÉTODO: Estudio de observación. Participaron 80 madres comunitarias y 12 pediatras expertos. Se desarrolló en dos etapas: la creación del instrumento a partir de las 7 fases propuestas por Sampieri, y la validación mediante la evaluación de validez aparente, de constructo, de contenido, consistencia interna y fiabilidad intra-observador. RESULTADOS: Se creó un instrumento autoadministrado que incluyó inicialmente 14 preguntas sobre conocimientos maternos y de cuidadores. Durante la validación de constructo se identificaron 3 dominios y se eliminaron cuatro preguntas. En la validación de contenido, 10 preguntas del instrumento definitivo obtuvieron calificaciones superiores a 9 (en una escala de 0-10) en las características: calidad, vocabulario, relevancia y actualidad. La consistencia interna global del instrumento fue moderada (Alfa de Cronbach: 0,64) y la fiabilidad intra-observador fue aceptable (k: 0,21-0,40) para el 80% de ítems del instrumento. CONCLUSIONES: Se presenta el primer instrumento autoadministrado validado en la región, que permite medir conocimientos de las madres y los cuidadores sobre alimentación complementaria. A futuro, permitirá diseñar y desarrollar estrategias de evaluación e intervención en relación con los conocimientos maternos y de los cuidadores sobre alimentación complementaria.

INTRODUCTION: Adequate nutrition during the first two years of life is crucial for the full development of human potential. Inadequate, early, or late introduction of complementary feeding has consequences in the short- and long-term. Complementary feeding depends largely on the knowledge of the caregiver who, in Latin American countries, is usually the mother. OBJECTIVE: To create and validate an ins trument to measure knowledge about complementary feeding. SUBJECTS AND METHOD: Observational study in which 80 community mothers and 12 expert pediatricians participated. It was carried out in two stages, the creation of the instrument (following the 7 phases proposed by Sampieri) and the va lidation through the evaluation of the apparent validity, construct and content validity, internal con sistency, and intra-observer reliability. RESULTS: A self-administered instrument was created that ini tially included 14 questions about maternal and caregiver's knowledge. During the validation of the construct, 3 domains were identified and four questions were eliminated. In the content validation, 10 questions of the final instrument scored higher than 9 (on a scale of 0-10) in the characteristics of quality, vocabulary, relevance, and topicality. The global internal consistency of the instrument was moderate (Cronbach's alpha: 0.64) and the intra-observer reliability was acceptable (k: 0.21-0.40) for 80% of its items. CONCLUSIONS: the first self-administered instrument validated in the region to measure the knowledge of mothers and caregivers about complementary feeding is presented. It will allow to design and develop strategies in relation to maternal and caregiver's knowledge of comple mentary feeding.

Valor diagnóstico de las clasificaciones outerbridge e ICRS para la clasificación artroscópica de lesiones condrales de rodilla / Diagnostic value of outerbridge and ICRS classifications for arthroscopic grading of chondral lesions in the knee

OBJETIVOS: Determinar el rendimiento de las clasificaciones de Outerbridge (OB) e International Cartilage Repair Society (ICRS). MÉTODO: Estudio de test diagnóstico, diseño y recolección de datos prospectivo. Siete traumatólogos sub-especialistas observaron un mismo video donde se exponían 30 lesiones condrales bajo visión artroscópica, para luego clasificarlas según OB e ICRS y consignar el tratamiento de elección para cada una de las lesiones, eligiendo entre 6 alternativas: observación, debridamiento mecánico o térmico, microfractura, OATS o terapias biológicas. Tras 7 días, los evaluadores debían repetir el mismo procedimiento. RESULTADOS: La concordancia entre los observadores fue débil para clasificación de ICRS (k 0,25 p < 0,001) y moderada para la clasificación de OB (k 0,45 p < 0,001). La concordancia intra-observador para ICRS oscilaba entre moderada y excelente (k promedio de 0,67), y para la clasificación de OB entre buena y excelente (k promedio 0,83). Ninguna de las dos clasificaciones mostró correlación con la experiencia del cirujano. En la elección de tratamiento, la concordancia entre observadores fue débil (k 0,33 p < 0,001), sin embargo, la concordancia intra-observador fue en todos los casos buena o excelente (k 0,82), mostrando una correlación directamente proporcional a la experiencia del cirujano. La capacidad de discriminación terapéutica, evaluada mediante una regresión logística, mostró un área bajo la curva roc en el rango del no-efecto. CONCLUSIÓN: Ambas clasificaciones mostraron una baja correlación inter-observador y una elevada concordancia intra-observador. En ambas categorías, Outerbridge fue más concordante que ICRS. En cuanto al tratamiento, ninguna de las dos clasificaciones logra unificar criterios quirúrgicos. NIVEL DE EVIDENCIA: Nivel I (test diagnóstico).

OBJECTIVES: Assess de diagnostic accuracy of Outerbridge (OB) and ICRS (International Cartilage Repair Society) classifications. METHODS: We performed a diagnostic test study, with a prospective design and data collection. Seven knee surgeons were asked to observe a video were the 30 chondral lesions were shown through arthroscopic view. Simultaneously they were asked to classify them according to OB and ICRS. Besides, they had to define how they would manage the chondral lesion, choosing among six treatment options (observation, mechanical or thermic chondroplasty, microfracture, osteochondral autologous transfer system (OATS) or biological therapies). A week later, they repeated the same procedure. Intra and interobserver agreement were characterized by κ statistical analysis, and a logistic regression was used to assess the ability of both classifications to discriminate among treatment options. P values < 0,05 were considered significant. RESULTS: Interobserver agreement was weak (κ 0.25 p < 0.001) for ICRS classification and moderate for OB classification (κ 0.45 p < 0.001). Intraobserver agreement for ICRS ranged from moderate to excellent (average κ of 0.67), and for the OB classification ranged from good to excellent (average kappa 0.83). Neither classification correlated with the surgeon's experience. Interobserver agreement for therapeutic choice was poor (κ 0.33 p < 0.001). However, intraobserver agreement was good to excellent (κ 0.82) in all cases, showing a direct correlation with the surgeon's experience. Logistic regression used to assess the ability of both classifications to discriminate among treatment options, showed in both cases an area under the roc curve in the no-effect range. CONCLUSION: Both classifications showed low interobserver and high intraobserver agreements for arthroscopic grading of chondral lesions. In both, Outerbridge was more reliable than ICRS. As for guiding therapeutic management, none of the classifications could unify surgical criteria.

La auscultación pulmonar en el siglo 21 / Lung auscultation in the 21th century

La auscultación pulmonar es parte fundamental del examen físico para el diagnóstico de las enfermedades respiratorias. La estandarización que ha alcanzado la nomenclatura de los ruidos respiratorios, sumado a los avances en el análisis computacional de los mismos, han permitido mejorar la utilidad de esta técnica. Sin embargo, el rendimiento de la auscultación pulmonar ha sido cuestionado por tener una concordancia variable entre profesionales de la salud. Aun cuando la incorporación de nuevas herramientas diagnósticas de imágenes y función pulmonar han revolucionado la precisión diagnóstica en enfermedades respiratorias, no existe tecnología que permita reemplazar la técnica de auscultación pulmonar para guiar el proceso diagnóstico. Por una parte, la auscultación pulmonar permite seleccionar a aquellos pacientes que se beneficiarán de una determinada técnica diagnóstica, se puede repetir cuantas veces sea necesario para tomar decisiones clínicas, y frecuentemente permite prescindir de exámenes adicionales que no siempre son fáciles de realizar o no se encuentran disponibles. En esta revisión se presenta el estado actual de la técnica de auscultación pulmonar y su rendimiento objetivo basado en la nomenclatura actual aceptada para los ruidos respiratorios, además de resumir la evidencia principal de estudios de concordancia de auscultación pediátrica y su análisis objetivo a través de nueva tecnología computacional.

Lung auscultation is an essential part of the physical examination for diagnosing respiratory diseases. The terminology standardization for lung sounds, in addition to advances in their analysis through new technologies, have improved the use of this technique. However, traditional auscultation has been questioned due to the limited concordance among health professionals. Despite the revolu tionary use of new diagnostic tools of imaging and lung function tests allowing diagnostic accuracy in respiratory diseases, no technology can replace lung auscultation to guide the diagnostic process. Lung auscultation allows identifying those patients who may benefit from a specific test. Moreover, this technique can be performed many times to make clinical decisions, and often with no need for- complicated and sometimes unavailable tests. This review describes the current state-of-the-art of lung auscultation and its efficacy based on the current respiratory sound terminology. In addition, it describes the main evidence on respiratory sound concordance studies among health professionals and its objective analysis through new technology.

Diagnostic accuracy of preoperative magnetic resonance imaging for detecting subscapularis tendon tears: a diagnostic test study

ABSTRACT BACKGROUND: The accuracy of magnetic resonance imaging (MRI) for making the diagnosis of subscapularis tears presents wide variation in the literature and there are few prospective studies. OBJECTIVE: To compare the findings from MRI and arthroscopy for diagnosing subscapularis tears. DESIGN AND SETTING: Diagnostic test study performed in a tertiary care hospital. METHODS: We included patients who underwent arthroscopic rotator cuff repair and who had firstly undergone high magnetic field MRI without contrast. The images were independently evaluated by a shoulder surgeon and two musculoskeletal radiologists. Sensitivity, specificity, positive and negative predictive values, accuracy and inter and intra-observer agreement were calculated. RESULTS: MRIs on 200 shoulders were evaluated. The incidence of subscapularis tears was 69.5% (41.5% partial and 28.0% full-thickness). The inter and intra-observer agreement was moderate for detection of subscapularis tears. The shoulder surgeon presented sensitivity of 51.1% to 59.0% and specificity of 91.7% to 94.4%. The radiologists showed sensitivity of 83.5% to 87.1% and specificity of 41% to 45.9%. Accuracy ranged from 60.5% to 73.0%. CONCLUSION: The 1.5-T MRIs without contrast showed mean sensitivity of 70.2% and mean specificity of 61.9% for detection of subscapularis tears. Sensitivity was higher for the musculoskeletal radiologists, while specificity was higher for the shoulder surgeon. The mean accuracy was 67.6%, i.e. lower than that of rotator cuff tears overall.

Concordance in prediction body fat percentage of Brazilian women in reproductive age between different methods of evaluation of skinfolds thickness

ABSTRACT Objective To assess the utility of bioimpedance (BIA) and skinfolds thickness (SF) in body fat percentage measuring (%BF) compared to the reference method dual-energy x-ray absorptiometry (DXA) in Brazilian reproductive age women, as well as to estimate of inter- and intra-observer precision for SF. Subjects and methods 170 women aged 18-37 years with BMI between 18 and 39.9 kg/m2 were selected for this cross-sectional study. Body density was evaluated through equations proposed by Jackson, Pollock and Ward (1980) (EqJPW) and Petroski (1995) (EqPET), and %BF was estimated by BIA, DXA and Siri's formula (1961). The SF were measured by two separate observers: A and B (to determine inter-observer variability), who measured the folds at three times with 10-minute interval between them (to determine intra-observer variability - we used only observer A). Results The %BF by DXA was higher than those measured by SF and BIA (p<0.01, for all) of 90 volunteers. The Lin coefficient of agreement was considered satisfactory for %BF values obtained by EqJPW and BIA (0.55) and moderate (0.76) for sum of SF (ΣSF) values obtained by EqJPW and EqPET. No agreement was observed for the values obtained by SF (EqJPW and EqPET), BIA and DXA. Analysis of inter- and intra-observer of 59 volunteers showed that different measures of SF thickness met acceptability standards, as well as the % BF. Conclusion BIA and SF measurements may underestimate %BF compared with DXA. In addition, BIA and SF measurements are not interchangeable with DXA. However, our results suggest the equation proposed by Jackson, Pollock and Ward (three skinfolds) compared to BIA are interchangeable to quantify the %BF in Brazilian women in reproductive age. Furthermore, our results show acceptable accuracy for intra- and inter-observer skinfold measurements. Arch Endocrinol Metab. 2020;64(3):257-68

Prominent autistic traits and subthreshold bipolar/mixed features of depression in severe anorexia nervosa

Objective: Autistic traits are associated with a burdensome clinical presentation of anorexia nervosa (AN), as is AN with concurrent depression. The aim of the present study was to explore the intertwined association between complex psychopathology combining autistic traits, subthreshold bipolarity, and mixed depression among people with AN. Method: Sixty patients with AN and concurrent major depressive episode (mean age, 22.2±7 years) were cross-sectionally assessed using the Autism-Spectrum Quotient test (AQ-test), the Hamilton depression scales for depression and anxiety, the Young Mania Rating Scale (YMRS), the Hypomania-Checklist-32 (HCL-32), second revision (for subthreshold bipolarity), the Brown Assessment and Beliefs Scale (BABS), the Yale-Brown-Cornell Eating Disorders Scale (YBC-EDS), and the Eating Disorder Examination Questionnaire (EDE-Q). Cases were split into two groups depending on body mass index (BMI): severe AN (AN+) if BMI < 16, not severe (AN-) if BMI ≥ 16. Results: The "subthreshold bipolarity with prominent autistic traits" pattern correctly classified 83.6% of AN patients (AN+ = 78.1%; AN- = 91.3%, Exp(B) = 1.391). AN+ cases showed higher rates of positive scores for YMRS items 2 (increased motor activity-energy) and 5 (irritability) compared to AN- cases. Conclusions: In our sample, depressed patients with severe AN had more pronounced autistic traits and subtly mixed bipolarity. Further studies with larger samples and prospective follow-up of treatment outcomes are warranted to replicate these findings.