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1.
Arch. pediatr. Urug ; 92(2): e210, dic. 2021. ilus, tab
Article in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1278303

ABSTRACT

Antecedentes: la nutrición durante el embarazo impacta en la salud del recién nacido, con efectos a nivel epigenético determinando consecuencias neurológicas a largo plazo. Las necesidades de hierro durante el embarazo se estiman en 27 mg/día. El hierro hemo que se absorbe mejor se encuentra en la carne. La determinación de ferritina en sangre de cordón umbilical permite evaluar los depósitos de hierro alcanzados durante la etapa fetal. Sus niveles se asociaron con efectos a largo plazo sobre el desarrollo infantil. Objetivos: el objetivo de este estudio de carácter exploratorio es determinar la relación entre el consumo de carnes rojas durante el tercer trimestre de gestación y el nivel de ferritina en el cordón umbilical. Métodos: se realizó un estudio observacional descriptivo con datos recolectados prospectivamente durante un año en el Departamento de Neonatología del Centro Hospitalario Pereira Rossell (CHPR) en Montevideo, Uruguay. Un total de 188 pacientes cumplieron los criterios de inclusión. Se extrajo sangre del cordón umbilical después de un pinzamiento estricto del cordón pasado un minuto de vida. La ferritina se midió utilizando el método de quimioinmunofluorescencia. Se aplicó una encuesta nutricional materna (cualitativo-cuantitativa) que midió la frecuencia de consumo de alimentos con fuente de hierro y las cantidades aproximadas consumidas durante el último trimestre del embarazo. Esta encuesta se centró en el consumo materno de carne vacuna como principal fuente de hierro hemínico en Uruguay. Se analizó la relación entre estas variables. Resultados: el déficit latente de hierro (ferritina en el cordón umbilical <100 ng/ml) se asoció con un menor consumo de carne vacuna durante el embarazo. Valor p de Fisher: 0,0133, OR: 3,71, IC del 95% (1,25-11,05). Conclusiones: este estudio considera adecuada la evidencia que relaciona que los niveles bajos de consumo total de hierro y de carne vacuna durante el tercer trimestre de gestación determinarán un mayor riesgo de déficit latente de hierro y de ferritina medido en el cordón umbilical. Los niveles descendidos de ferritina en cordón umbilical se asocian con un mayor riesgo de efectos adversos a largo plazo sobre la mielinización y el desarrollo neurocognitivo.


Background: nutrition during pregnancy impacts the foetus and the newborn health, it has consequences at the epigenetic level and determines long-term neurological consequences. Iron requirements during pregnancy are estimated at 27 mg/day. Iron is blood absorption from is most efficient from beef. Umbilical cord blood ferritin levels can be used to assess iron deposits reached during the foetal stage. Ferritin levels are linked to the child's long-term development. Objective: this exploratory study's objective is to determine the relationship between beef consumption during the first quarter of pregnancy and ferritin levels in the umbilical cord. Methods: we carried out a descriptive, observational study with prospectively collected data for one-year at the Neonatology Department of the Pereira Rossell Hospital Center (CHPR) in Montevideo, Uruguay. A total of 188 patients met the inclusion criteria. We extracted umbilical cord blood after a strict cord clamping after one minute of life. Ferritin was measured using the chemoimmunofluorescence method. We carried out a maternal nutritional survey using a qualitative-quantitative method and measured the frequency and approximate quantity of iron source food consumption during the last quarter of pregnancy. This survey was focused on maternal beef consumption as the major heme iron source in Uruguay. We analyzed the relationship between these variables. Results: latent iron deficiency (ferritin in the umbilical cord <100 ng / ml) was associated with lower beef consumption during pregnancy. Fisher p-value: 0.0133, OR: 3.71, 95% CI (1.25 - 11.05). Conclusions: this study agrees with the evidence that shows that low levels of total iron and beef consumption during pregnancy determine an increased risk of latent iron deficiency and lower levels of ferritin in newborns, and therefore, greater risk of long-term adverse effects on myelination and neurocognitive development.


Contexto: a nutrição durante a gravidez tem impacto sobre a saúde do recém-nascido, com efeitos no nível epigenético, determinando consequências neurológicas a longo prazo. As necessidades de ferro durante a gravidez são estimadas em 27 mg / dia. O ferro heme de melhor absorção e aquele encontrado na carne vacuna. A determinação da ferritina no sangue do cordão umbilical permite avaliar os depósitos de ferro atingidos na fase fetal. Seus níveis foram associados a efeitos de longo prazo no desenvolvimento das crianças. Objetivos: o objetivo deste estudo exploratório é determinar a relação entre o consumo de carne vermelha durante o terceiro trimestre de gestação e o nível de ferritina no cordão umbilical. Métodos: foi realizado um estudo observacional descritivo com dados coletados prospectivamente durante um ano no Departamento de Neonatologia do Centro Hospitalar Pereira Rossell (CHPR) em Montevidéu, Uruguai. Um total de 188 pacientes cumpriram os critérios de inclusão. O sangue do cordão umbilical foi coletado após clampeamento estrito do cordão após um minuto de vida da criança. A ferritina foi medida pelo método de quimioimunofluorescência. Aplicamos um inquérito nutricional materno (qualitativo-quantitativo) que mediu a frequência de consumo de alimentos com fonte de ferro e as quantidades aproximadas consumidas durante o último trimestre da gravidez. Esta pesquisa enfocou o consumo materno de carne bovina como principal fonte de ferro heme no Uruguai. A relação entre essas variáveis foi analisada. Resultados: a deficiência latente de ferro (ferritina no cordão umbilical <100 mg / ml) foi associada ao menor consumo de carne bovina durante a gestação. Valor de p de Fisher: 0,0133, OR: 3,71, IC 95% (1,25-11,05). Conclusões: este estudo concorda com as evidências que relacionam que os baixos níveis de ferro total e consumo de carne bovina durante o terceiro trimestre de gestação determinam um maior risco de déficit de ferro latente e ferritina mensurado no cordão umbilical. A redução dos níveis de ferritina no cordão umbilical está associada a um risco aumentado de efeitos adversos de longo prazo na mielinização e no desenvolvimento neurocognitivo.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Hemoglobins/analysis , Parenteral Nutrition , Ferritins/blood , Fetal Blood , Red Meat , Pregnancy Trimester, Third , Uruguay , Iron Deficiency/complications , Child Development/physiology , Epidemiology, Descriptive
2.
Arq. gastroenterol ; 58(3): 402-404, July-Sept. 2021. tab
Article in English | LILACS | ID: biblio-1345303

ABSTRACT

ABSTRACT BACKGROUND: There is controversy about the initiation of gastric or oral feeding in patients with severe acute pancreatitis (SAP) because they could increase pancreatic stimulation and exacerbate symptoms and complications. OBJECTIVE: To describe the clinical characteristics and results of patients with SAP who underwent gastric tube or oral feeding versus parenteral or jejunal feeding. METHODS: A retrospective study was carried out on patients over 18 years old with SAP diagnostic, who had been treated in critical care units. We excluded patients coming from other hospitals and those with incomplete medical records. RESULTS: Thirty patients with SAP were included, fifty three percent of them tolerated the gastric tube or oral feeding, and most of them were females and older than patients who received parenteral or jejunal feeding. Other clinical characteristics and outcomes were similar in both groups. Conclusion: Gastric tube or oral feeding is no absolute contraindication for SAP.


RESUMO CONTEXTO Há controvérsias sobre o início da alimentação gástrica ou oral em pacientes com pancreatite aguda grave (PAG), pois elas podem aumentar a estimulação pancreática e exacerbar os sintomas e complicações. OBJETIVO Descrever as características clínicas e os resultados de pacientes com PAG submetidos à alimentação por sonda gástrica ou via oral versus alimentação parenteral ou jejunal. MÉTODOS Foi realizado um estudo retrospectivo em pacientes maiores de 18 anos com diagnóstico de PAG, atendidos em unidades de terapia intensiva. Excluímos pacientes procedentes de outros hospitais e aqueles com prontuário incompleto. RESULTADOS Trinta pacientes com PAG foram incluídos, 53% deles toleravam a sonda gástrica ou alimentação via oral, e a maioria era do sexo feminino e tinha mais idade do que os pacientes que receberam alimentação parenteral ou jejunal. Outras características clínicas e resultados foram semelhantes em ambos os grupos. CONCLUSÃO A sonda gástrica ou alimentação oral não é contra-indicação absoluta para PAG.


Subject(s)
Humans , Female , Adolescent , Pancreatitis/complications , Acute Disease , Retrospective Studies , Enteral Nutrition , Parenteral Nutrition
3.
Cambios rev. méd ; 20(1): 94-98, 30 junio 2021. ilus.
Article in Spanish | LILACS | ID: biblio-1292976

ABSTRACT

INTRODUCCIÓN. El quilotórax resulta de un daño al conducto torácico por ruptura, laceración, desgarro o compresión. Es una patología rara de derrame pleural en la edad pediátrica, pero frecuente como complicación posterior a cirugía cardiotorácica. La base del tratamiento conservador se ha fundamentado en: drenaje inicial, modificación de la dieta, uso de somatostatina o análogos sintéticos como octreotide, cirugía, prevención y manejo de complicaciones. Fue preciso describir la experiencia institucional clínica así como su abordaje. CASO CLÍNICO. Paciente masculino de 4 meses de edad, que ingresó a la Unidad Pediátrica Área de Emergencias del Hospital de Especialidades Carlos Andrade Marín, el 13 de septiembre de 2019 con antece-dente quirúrgico de atresia de esófago corregida en etapa neonatal. Acudió con dificultad respiratoria, radiografía de tórax que evidenció derrame pleural derecho, toracentesis diagnóstica con salida de líquido de aspecto turbio y lechoso; se colocó tubo de tórax derecho. Se prescribió ayuno inicial, nutrición parenteral durante 4 semanas hasta comprobar resolución del quilotórax. Fue dado de alta en condición estable tras 43 días de hospitalización. DISCUSIÓN. La evidencia científica registró que el tratamiento conservador del quilotórax se basó en: drenaje, reposo digestivo inicial, nutrición parenteral, modificación cualitativa de la dieta enteral y uso de octreotide; el mismo que fue aplicado al paciente de este caso clínico con evolución favorable. CONCLUSIÓN. El tratamiento conservador y multidisciplinario en el abordaje del qui-lotórax fue exitoso y no necesitó manejo quirúrgico.


INTRODUCTION. Chylothorax results from damage to the thoracic duct by rupture, la-ceration, tear or compression. It is a rare pathology of pleural effusion in pediatric age, but frequent as a complication after cardiothoracic surgery. The basis of conservative treatment has been based on: initial drainage, diet modification, use of somatostatin or synthetic analogues such as octreotide, surgery, prevention and management of complications. It was necessary to describe the clinical institutional experience as well as its approach. CLINICAL CASE. A 4-month-old male patient was admitted to the Emergency Area Pediatric Unit of the Carlos Andrade Marín Specialties Hospital on september 13, 2019 with a surgical history of esophageal atresia corrected in the neonatal stage. He went with respiratory distress, chest X-ray that showed right pleural effusion, diagnostic thoracentesis with outflow of cloudy and milky fluid; a right chest tube was placed. Initial fasting was prescribed, parenteral nutrition for 4 weeks until resolution of the chylothorax was verified. He was discharged in stable condition after 43 days of hospitalization. DISCUSSION. The scientific evidence recorded that the conservative treatment of chylothorax was based on: drainage, initial digestive rest, parenteral nutrition, qualitative modification of enteral diet and use of octreotide; the same that was applied to the patient of this clinical case with favorable evolu-tion. CONCLUSION. Conservative and multidisciplinary treatment in the approach to chylothorax was successful.


Subject(s)
Humans , Male , Infant , Thoracic Duct , Somatostatin , Chylothorax/surgery , Parenteral Nutrition , Pediatric Emergency Medicine , Intensive Care Units, Pediatric , Tracheoesophageal Fistula , Esophageal Atresia
4.
Arch. argent. pediatr ; 119(5): e441-e472, oct. 2021. tab, ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1292123

ABSTRACT

La falla intestinal secundaria a síndrome de intestino corto en pediatría es una entidad poco frecuente, de alta morbimortalidad. Requiere de un equipo interdisciplinario para su abordaje, lo cual ha demostrado que disminuye la morbimortalidad y aumenta la posibilidad de que los pacientes logren la autonomía intestinal. Existe una falta de evidencia científica en diferentes abordajes de la patología. Consideramos necesario el desarrollo de esta Guía para el Manejo Clínico construida sobre la base de la metodología Delphi modificada, en la Asociación Argentina de Nutrición Enteral y Parenteral, por 16 expertos que se reunieron para discutir y consensuar los principales aspectos de tratamiento clínico. Se analizaron 4 aspectos: definiciones y epidemiología; nutrición enteral, nutrición parenteral; tratamientos farmacológicos y quirúrgicos,y criterios de derivación a centros de alta complejidad. Sin duda este documento será de utilidad para los pacientes, los profesionales y las instituciones, así como para los diferentes financiadores del sistema de salud.


Intestinal failure secondary to short bowel syndrome in pediatrics, is a rare condition with high morbimortality. A follow up multidisciplinary team is necessary to minimize complications and optimize the intestinal rehabilitation. There are no gold standard guidelines for the management of this group of complex patients. The development of clinical guidelines may contribute for an adequate management of patients with intestinal failure and short bowel syndrome. This Clinical Guideline for the Management was developed by 16 experts based on modified Delphi methodology. The meetings were held at the Argentinian Association of Enteral and Parenteral Nutrition (Asociación Argentina de Nutrición Enteral y Parenteral); the topics analyzed were definitions, epidemiology, enteral and parenteral nutrition, pharmacological and surgical treatments, and criteria for referring patients to intestinal rehabilitation centers. The document is aimed to provide basic scientific knowledge for medical institutions, health providers, healthcare providers, patients and families.


Subject(s)
Humans , Child , Pediatrics , Short Bowel Syndrome/complications , Short Bowel Syndrome/therapy , Parenteral Nutrition , Intestine, Small , Intestines
5.
Article in Chinese | WPRIM | ID: wpr-879865

ABSTRACT

OBJECTIVE@#To systematically evaluate the association of early nutrition intake with the risk of bronchopulmonary dysplasia (BPD).@*METHODS@#PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Wanfang Data, and Weipu Periodical Database were searched for the observational studies on the association between early nutrition intake and BPD. RevMan 5.3 software was used to perform a Meta analysis of eligible studies.@*RESULTS@#Eight observational studies were included, with 548 infants with BPD and 522 infants without BPD. The Meta analysis showed that the BPD group had a significantly lower caloric intake than the non-BPD group within the first week after birth and in the first 2 weeks after birth (@*CONCLUSIONS@#Early nutrition deficiency may be associated with the development of BPD, and more attention should be paid to enteral feeding of infants at a high risk of BPD to achieve total enteral feeding as soon as possible.


Subject(s)
Bronchopulmonary Dysplasia/etiology , China , Humans , Infant , Infant, Newborn , Infant, Premature , Malnutrition , Parenteral Nutrition
6.
Article in Chinese | WPRIM | ID: wpr-879838

ABSTRACT

OBJECTIVE@#To study the clinical effect of multi-oil fat emulsion for parenteral nutrition support in extremely low birth weight (ELBW) infants.@*METHODS@#A retrospective analysis was performed for 49 ELBW infants who were admitted from January 1, 2018 to July 30, 2020, with an age of ≤14 days on admission and a duration of parenteral nutrition of > 14 days. According to the type of lipid emulsion received, the ELBW infants were divided into two groups: soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) (@*RESULTS@#The 49 ELBW infants had a mean birth weight of (892±83) g and a mean gestational age of (28.2±2.3) weeks. There was no significant difference between the two groups in the incidence rates of hemodynamically significant patent ductus arteriosus, intraventricular hemorrhage, neonatal necrotizing enterocolitis, retinopathy of prematurity, bronchopulmonary dysplasia (BPD), grade Ⅲ BPD, sepsis, and pneumonia (@*CONCLUSIONS@#The application of multi-oil fat emulsion in ELBW infants does not reduce the incidence rate of complications, but compared with MCT/LCT emulsion, SMOF can reduce the severity of PNAC in ELBW infants.


Subject(s)
Birth Weight , Emulsions , Fat Emulsions, Intravenous , Humans , Infant , Infant, Extremely Low Birth Weight , Infant, Newborn , Parenteral Nutrition , Retrospective Studies , Soybean Oil
7.
Article in Chinese | WPRIM | ID: wpr-879818

ABSTRACT

OBJECTIVE@#To explore the reasonable and effective enteral nutrition regimen for children with abdominal Henoch-Schönlein purpura (HSP).@*METHODS@#A retrospective analysis was performed on the medical data of children with abdominal HSP who were hospitalized from August 2013 to August 2018. According to the starting time of enteral nutrition after abdominal pain relief, the children were divided into three groups: < 24 hours (@*RESULTS@#The retrospective analysis showed that the children who were given extensively hydrolyzed lactoprotein formula for enteral nutrition at 24-48 hours after abdominal pain relief had a lower recurrence rate of clinical symptoms and the highest degree of satisfaction among their family members (@*CONCLUSIONS@#It is reasonable and effective to start the feeding with extensively hydrolyzed lactoprotein formula at 24-48 hours after abdominal pain relief in children with abdominal HSP.


Subject(s)
Child , Enteral Nutrition , Humans , Parenteral Nutrition , Prospective Studies , Purpura, Schoenlein-Henoch/therapy , Retrospective Studies
8.
Rev. epidemiol. controle infecç ; 10(3): 1-15, jul.-set. 2020. ilus
Article in Portuguese | LILACS | ID: biblio-1247589

ABSTRACT

Justificativa e objetivos: A Nutrição Parenteral Total (NPT) possui grande importância clínica no tratamento e prevenção da desnutrição de pacientes com problemas no sistema digestório. Apesar das boas práticas de manipulação de NPT estarem bem estabelecidas, a contaminação desses produtos ainda ocorre, e esses produto permanecem como um medicamento de alto risco pelo Institute for Safe Medication Practices. O presente estudo teve como objetivo obter um panorama sobre os dados documentais das amostras de nutrição parenteral encaminhadas ao Instituto Nacional de Controle de Qualidade em Saúde da Fundação Oswaldo Cruz. Métodos: Foi realizado um estudo qualitativo descritivo e quantitativo, com base em um coorte transversal de amostras de NPT analisadas no período de 2000 a 2016. Resultados: Foram encaminhadas 134 amostras de NPT no período do estudo. 11,20% das amostras foram encaminhadas em 2001, 0,80%, em 2005, 8,20%, em 2006, 16,40% em 2007, 63,40% em 2013. Seis amostras (4,5%) foram canceladas e 113 submetidas ao ensaio de esterilidade, resultando em 13,3% de amostras insatisfatórias. Conclusão: No período do estudo, quatro eventos suspeitos de contaminação bacteriana por enterobactérias em NPTs administradas em pacientes foram relatados, sendo três deles ainda não descritos na literatura. Para que a segurança dos pacientes que fazem uso de NPT seja garantida, sugere-se que as normas que regulamentam a terapia com NPT sejam revisadas e atualizadas e sejam estabelecidos programas de monitoramento da qualidade dessas preparações.(AU)


Background and objectives: Total parenteral nutrition (TPN) has great clinical importance in malnutrition treatment and prevention in patients with digestive problems. Although good practices for handling TPN are well established, contamination of these products still occurs, and this product remains listed as a higher risk drug by the Institute for Safe Medication Practices. The present study aimed to obtain an overview of the documentary data of the parenteral nutrition samples sent to the National Institute for Quality Control in Health (INCQS) of Fundação Oswaldo Cruz. Methods: This is a qualitative descriptive and quantitative study carried out based on a cross-section of TPN samples analyzed from 2000 to 2016. Results: A total of TPN 134 samples were sent during the study period. 11.20% of the samples were sent in 2001, 0.80% in 2005, 8.20% in 2006, 16.40% in 2007, 63.40% in 2013. Six samples (4.5%) were canceled and 113 submitted to sterility testing, resulting in 13.3% unsatisfactory samples. Conclusion: During the study period, four suspected events of enterobacterial contamination in TPNs administered to patients were reported, three of which have not yet been described in the scientific literature. For the safety of patients using TPN to be guaranteed, it is suggested that the norms that regulate TPN therapy be reviewed and updated, and programs to monitor the quality of these preparations should be established.(AU)


Justificatión y objetivos: La Nutrición Parenteral Total (NPT) tiene una gran importancia clínica en el tratamiento y la prevención de la desnutrición en pacientes con problemas en el sistema digestivo. Aunque las buenas prácticas para el manejo del TNP están bien establecidas, la contaminación de estos productos aún ocurre, y este producto sigue siendo catalogado como un medicamento de alto riesgo por el Institute for Safe Medication Practices. El presente estudio tuvo como objetivo obtener una visión general de los datos documentales de muestras de nutrición parenteral enviadas a Instituto Nacional de Control de Calidad en Salud (INCQS) por Fundação Oswaldo Cruz. Métodos: Se realizó un estudio descriptivo cualitativo y cuantitativo basado en una sección transversal de muestras de NPT analizadas entre 2000 y 2016. Resultados: Se enviaron un total de 134 muestras de NPT durante el período de estudio. 11,20% de las muestras enviadas en 2001, 0,80%, en 2005, 8,20%, en 2006, 16,40%, en 2007, 63,40%, en 2013. Seis muestras (4,5%) fueron cancelados y 113 sometidos a la prueba de esterilidad, resultando en 13,3% de muestras insatisfactorias. Conclusión: Durante el período de estudio, se informaron cuatro eventos sospechosos de contaminación por enterobaterias en NPT administrados a pacientes, tres de los cuales aún no se han descrito en la literatura. Para garantizar la seguridad de pacientes que usan NPT, se sugiere revisar y actualizar las normas que regulan la terapia de NPT y se deben establecer programas para controlar la calidad de estas preparaciones.(AU)


Subject(s)
Humans , Quality Control , Parenteral Nutrition, Total , Parenteral Nutrition , Health Surveillance , Good Manipulation Practices
9.
Invest. educ. enferm ; 38(2): [e08], junio 30 2020.
Article in English | LILACS, BDENF, COLNAL | ID: biblio-1103578

ABSTRACT

Objective. This work sought to describe the meaning of receiving artificial nutritional support in people in the postoperative period of abdominal surgery. Methods. This was a qualitative study of grounded theory, following the guidelines by Corbin and Strauss. The information was collected through 26 in-depth interviews with 21 participants, interned in a tier III health care hospital in the city of Tunja, Colombia. Results. The study describes four categories, which account for the way in which the person experiences physical, physiological, emotional, and social changes when receiving artificial nutritional support. The categories include stopping eating and becoming artificially fed, decreasing the ability to move to recover movement, experiencing the difficulty of having artificial nutritional support, and reaching the disease to transform life. The data analysis shows that the basic surgical pathology and the artificial nutritional support are sudden events that fragment the daily life of the person. These individuals demand the mobilization of religious, family, and social resources to strengthen the person's internal and external environment and, thus, achieve the health situation. Conclusions. The analysis of the meanings shows how the person reflects and interprets the reality of receiving artificial nutritional support, an event that has implicit physical discomfort, emotional changes, and physical appearance, which are determinants in the behavior and practice of artificial nutrition. However, artificial nutritional support becomes for the person an alternative to live and recover the state of health.


Objetivo. Describir los significados de recibir soporte nutricional artificial en personas en periodo postoperatorio de cirugía abdominal. Métodos. Estudio cualitativo de teoría fundamentada, siguiendo los lineamientos de Corbin y Strauss. La información se recolectó a partir de 26 entrevistas en profundidad a 21 participantes internados en un hospital de tercer nivel de atención en salud de la ciudad de Tunja (Colombia). Resultados. El estudio describe cuatro categorías que dan cuenta de la forma en que la persona experimenta cambios físicos, fisiológicos, emocionales y sociales al recibir soporte nutricional artificial en el postoperatorio de cirugía abdominal: 1. dejar de comer y pasar a ser alimentado de manera artificial; 2. disminuyendo la capacidad de moverse hasta recobrar el movimiento; 3. experimentando lo difícil de tener el soporte nutricional artificial, y 4. la enfermedad llega para transformar la vida. La patología quirúrgica de base y el soporte nutrición artificial son eventos súbitos, que fragmentan la vida cotidiana de la persona. En consecuencia, demandan la movilización de recursos religiosos, familiares y sociales para el fortalecimiento del medio interno y externo de la persona y lograr así asumir la situación de salud. Conclusión. El análisis de los significados muestra cómo la persona reflexiona e interpreta la realidad de recibir soporte nutricional artificial, evento que tiene implícito molestias físicas, cambios emocionales y en la apariencia física, los cuales determinan en el comportamiento y prácticas de la persona. El soporte nutricional artificial se convierte para la persona en una alternativa para vivir y recuperar el estado de salud.


Objetivo. Descrever os significados de receber suporte nutricional artificial em pessoas no pós-operatório de cirurgia abdominal. Métodos Estudo qualitativo da teoria fundamentada, seguindo as diretrizes de Corbin e Strauss. As informações foram coletadas através de 26 entrevistas em profundidade com 21 participantes, internados em um hospital de terceiro nível para atendimento de saúde na cidade de Tunja (Colômbia). Resultados O estudo descreve quatro categorias que explicam a maneira pela qual a pessoa experimenta mudanças físicas, fisiológicas, emocionais e sociais, recebendo apoio nutricional artificial no período pós-operatório de cirurgia abdominal: parar de comer e se alimentar artificialmente, reduzindo a capacidade de se mover para recuperar o movimento, enfrentando a dificuldade de ter suporte nutricional artificial e levar a doença a transformar a vida. A patologia cirúrgica básica e o suporte nutricional artificial são eventos repentinos, que fragmentam o cotidiano da pessoa. Eles exigem a mobilização de recursos religiosos, familiares e sociais para fortalecer o ambiente interno e externo da pessoa e, assim, alcançar a situação de saúde. Conclusão A análise dos significados mostra como a pessoa reflete e interpreta a realidade de receber suporte nutricional artificial, um evento que implica desconforto físico implícito, mudanças emocionais e aparência física, determinantes de comportamento e prática diante da nutrição artificial. No entanto, o suporte nutricional artificial torna-se para a pessoa uma alternativa para viver e recuperar o estado de saúde.


Subject(s)
Humans , Postoperative Period , Enteral Nutrition , Parenteral Nutrition , Nutritional Support , Qualitative Research
10.
Rev. chil. nutr ; 47(2): 292-298, abr. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1115501

ABSTRACT

La clasificación de la severidad de la pancreatitis aguda ha cambiado con la actualización de Atlanta del 2012. Las recomendaciones de terapia nutricional en los casos de pancreatitis aguda grave no están sustentadas en estudios con alto nivel de evidencia, en los estudios se incluyen pacientes con los diferentes grados de severidad, se usa la clasificación de Atlanta 2002 para definir la pancreatitis aguda grave y, en la mayoría de los estudios experimentales, los controles son pacientes con nutrición parenteral. Se realiza una revisión narrativa de la evidencia actual publicada, analizando las características clínico epidemiológica de los pacientes y los resultados obtenidos. Así, se proponen características que deben ser consideradas en estudios futuros sobre el tema.


The classification of the severity of acute pancreatitis has changed with respect to the Atlanta update of 2012. The recommendations for nutritional therapy in cases of severe acute pancreatitis are not supported by high-level studies, as studies contain a mix of patients with different degrees of severity. The Atlanta 2002 classification is used to define severe acute pancreatitis and, in most of experimental studies, controls are patients with parenteral nutrition. A narrative review of the current published evidence is carried out analyzing the clinical and epidemiological characteristics of the patients in these results and characteristics to be included in future studies are proposed.


Subject(s)
Humans , Pancreatitis/therapy , Nutrition Therapy/methods , Pancreatitis/complications , Pancreatitis/physiopathology , Severity of Illness Index , Acute Disease , Enteral Nutrition , Parenteral Nutrition
11.
Clin. biomed. res ; 40(3): 167-172, 2020. graf, tab
Article in English | LILACS | ID: biblio-1248222

ABSTRACT

Introduction: To assess the use of nutritional support in children and adolescents submitted to autologous hematopoietic stem cell transplantation (HSCT), and analyze changes in nutritional status at hospital discharge after HSCT. Methods: A retrospective observational study was conducted on pediatric oncology patients hospitalized for autologous HSCT between 2010 and 2017. Nutritional therapy was evaluated based on the duration of enteral tube feeding (ETF) and parenteral nutrition (PN), either alone or in combination. The length of hospital stay was measured in days. Nutritional status was assessed at admission and discharge, and classified according to World Health Organization criteria. Results: The sample consisted of 68 patients, 54.4% of whom were boys. Most participants (89.7%) had solid tumors. Nutritional therapy was required in over half (52.9%) of cases, with PN being the most common indication. There was a reduction in the percentage of overweight patients and an increase in the percentage of underweight patients at discharge relative to admission. Conclusions: The use of nutritional therapy is highly prevalent in this population, and HSCT has a negative impact on nutritional status at discharge. (AU)


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Nutritional Status , Nutritional Support , Transplant Recipients , Thinness , Enteral Nutrition , Parenteral Nutrition , Hematopoietic Stem Cell Transplantation , Length of Stay , Obesity
12.
Einstein (Säo Paulo) ; 18: AE4530, 2020. tab, graf
Article in English | LILACS | ID: biblio-1056061

ABSTRACT

ABSTRACT The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment. The impairment of nutritional status during hematopoietic stem cell transplant occurs mainly due to the adverse effects resulting from conditioning to which the patient is subjected. Therefore, adequate nutritional evaluation and follow-up during hematopoietic stem cell transplant are essential. To emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to the nutritional assessment of the patient, the Brazilian Consensus on Nutrition in Hematopoietic Stem Cell Transplant: Adults was prepared, aiming to standardize and update Nutritional Therapy in this area. Dietitians, nutrition physicians and hematologists from 15 Brazilian centers thar are references in hematopoietic stem cell transplant took part.


RESUMO O estado nutricional do paciente submetido ao transplante de células-tronco hematopoéticas é considerado fator de risco independente, podendo influenciar na qualidade de vida e na tolerância ao tratamento proposto. O comprometimento do estado nutricional durante o transplante de células-tronco hematopoéticas ocorre principalmente devido aos efeitos adversos decorrentes do condicionamento ao qual o paciente é submetido. Desta forma, a adequada avaliação nutricional e o acompanhamento durante o transplante de células-tronco hematopoéticas tornam-se imprescindíveis. Com o objetivo de salientar a importância do estado nutricional e da composição corporal durante o tratamento, bem como as principais características relacionadas à avaliação nutricional do paciente, o Consenso Brasileiro de Nutrição em Transplante de Células-Tronco Hematopoiéticas: Adulto foi elaborado visando uniformizar e atualizar a Terapia Nutricional nesta área. Com a participação de nutricionistas, nutrólogos e hematologistas de 15 centros brasileiros referências em transplante de células-tronco hematopoéticas


Subject(s)
Humans , Adult , Nutritional Status , Hematopoietic Stem Cell Transplantation/standards , Nutrition Therapy/standards , Brazil , Nutrition Assessment , Anthropometry , Parenteral Nutrition/methods , Parenteral Nutrition/standards , Hematopoietic Stem Cell Transplantation/adverse effects , Transplantation Conditioning , Nutrition Therapy/methods
14.
Rev. méd. Urug ; 35(4): 316-324, dic. 2019. tab, fig
Article in Spanish | LILACS | ID: biblio-1026161

ABSTRACT

Cuando la falla intestinal ocurre luego de una resección intestinal masiva se denomina síndrome de intestino corto. Es una entidad rara, con un espectro clínico que va desde una disfunción leve y reversible hasta una condición grave e incapacitante. Presenta una elevada morbimortalidad, altos costos de atención médica e importante impacto en la calidad de vida. El 50% de los pacientes con síndrome de intestino corto no se adaptan espontáneamente ni mejoran la absorción por el intestino remanente, por lo que deben recurrir de por vida a la nutrición parenteral. La terapia nutricional especializada y el tratamiento hormonal focalizado en el intestino son pilares en la rehabilitación promoviendo la adaptación intestinal, logrando independencia de la nutrición parenteral y evitando el trasplante intestinal. Actualmente, teduglutide es el tratamiento de referencia en estos pacientes, pero hasta el momento inaccesible en Uruguay por su elevado costo. Presentamos el único caso en nuestro país de un paciente de 23 años portador de falla intestinal crónica por síndrome de intestino corto que depende de la nutrición parenteral desde hace 17 años y presenta complicaciones graves asociadas a esta técnica.


Short bowel syndrome consists of intestinal failure after a massive intestinal resection. It is an unusual condition, ranging from a mild and reversible malfunction to a severe condition causing inability. Short bowel syndrome has high morbimortality, high medical costs and a significant impact on quality of life. 50% of patients with short bowel syndrome do not spontaneously adapt and neither does absorption improve by the remaining intestine, thus they depend on parenteral nutrition for the rest of their lives. Specialized nutritional therapy and focalized hormone therapy in the intestine are pillars in rehabilitation. They promote intestine adaptation and achieve independence from parenteral nutrition and avoid intestinal transplant. Today, Teduglutide is the reference treatment for these patients, although it is still not available in Uruguay due to its high cost. The study presents a 23 year old patient carrier of chronic intestinal failure due to short bowel syndrome who has depended on parenteral nutrition for 17 years and presents severe complications associated to this technique.


Quando a falência intestinal ocorre depois de uma ressecção intestinal massiva é chamada Síndrome de intestino curto. É uma entidade rara, com um espectro clínico que pode manifestar-se por uma disfunção leve e reversível até um quadro grave e incapacitante. Apresenta alta morbimortalidade, altos custos de atenção médica e grande impacto sobre a qualidade de vida do paciente. 50% dos pacientes com síndrome de intestino curto não se adaptam espontaneamente nem conseguem uma melhoria da absorção pelo intestino restante sendo obrigados a utilizar nutrição parenteral de forma permanente. A terapia nutricional especializada e o tratamento hormonal focado no intestino são as bases da reabilitação promovendo a adaptação intestinal, diminuindo a dependência da nutrição parenteral e evitando o transplante intestinal. Atualmente o Teduglutide é o tratamento de referência para estes pacientes, porém devido ao seu elevado custo não é acessível aos pacientes no Uruguai. Apresentamos o único caso no país, de um paciente de 23 anos portador de falência intestinal crônica por síndrome de intestino curto que depende de nutrição parenteral há 17 anos e apresenta complicações graves associadas a esta técnica.


Subject(s)
Adult , Short Bowel Syndrome/complications , Parenteral Nutrition
15.
Rev. enferm. UERJ ; 27: e44521, jan.-dez. 2019. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1053550

ABSTRACT

Objetivo: identificar as necessidades humanas básicas alteradas nos neonatos com cateter central de inserção periférica em Unidade de Terapia Intensiva Neonatal, à luz da Teoria das Necessidades Humanas Básicas. Método: estudo transversal de abordagem quantitativa, realizado com 108 recém-nascidos em uma maternidade do Nordeste brasileiro entre os meses de fevereiro e dezembro de 2017. O instrumento de coleta de dados utilizado foi um roteiro de anamnese e exame físico. Os resultados foram analisados por meio da Teoria de Wanda Horta. Resultados: foram identificadas dez necessidades alteradas, com destaque para as mais prevalentes: integridade cutâneo-mucosa, ambiente, nutrição, hidratação, oxigenação e atenção. Conclusão: a identificação das necessidades humanas básicas alteradas nos neonatos com cateter central de inserção periférica pode subsidiar a elaboração de um plano de cuidados baseado em evidências e direcionado para essa população.


Objective: to identify the changed basic human needs in neonates with peripherally inserted central catheter, in light of the Theory of Basic Human Needs. Method: cross-sectional study, conducted with 108 newborns in a maternity hospital in the Northeast of Brazil between February and December 2017. An anamnesis and physical examination script was used for data collection. The results were analyzed using the Wanda Horta Theory. Results: ten altered needs were identified, highlighting the most prevalent ones: mucosal skin integrity, environment, nutrition, hydration, oxygenation and attention. Conclusion: the identification of altered basic human needs in neonates with peripherally inserted central catheter may support the elaboration of a care plan based on scientific evidences and directed to this population..


Objetivo: identificar las necesidades humanas básicas alteradas en recién nacidos con catéteres centrales insertados periféricamente en una Unidad de Cuidados Intensivos Neonatales, a la luz de la Teoría de las Necesidades Humanas Básicas. Método: estudio de enfoque cuantitativo, transversal, realizado con 108 recién nacidos en una maternidad en el nordeste de Brasil entre febrero y diciembre de 2017. El instrumento de recolección de datos utilizado fue un guión de historia y examen físico. Los resultados se analizaron utilizando la teoría de Wanda Horta. Resultados: se identificaron diez necesidades alteradas, destacando las más frecuentes: integridad de la piel, medio ambiente, nutrición, hidratación, oxigenación y atención. Conclusión: la identificación de necesidades humanas básicas alteradas en neonatos con catéter central insertado periféricamente puede apoyar la elaboración de un plan de atención basado en evidencias científicas y dirigido a esta población.


Subject(s)
Humans , Male , Female , Infant, Newborn , Nursing Theory , Infant, Newborn , Catheterization, Central Venous , Catheterization, Peripheral/nursing , Intensive Care Units, Neonatal , Nursing Process , Catheterization, Peripheral , Cross-Sectional Studies , Parenteral Nutrition , Nursing Care
16.
J. pediatr. (Rio J.) ; 95(6): 713-719, Nov.-Dec. 2019. tab
Article in English | LILACS | ID: biblio-1056665

ABSTRACT

ABSTRACT Objective: To describe the epidemiology and clinical features of acute pancreatitis and recurrent acute pancreatitis in children. Methods: Observational and retrospective study with an analytical component. Patients were classified into two groups: Acute pancreatitis and recurrent pancreatitis. The relationship with each parameter obtained was analyzed using the chi-squared test, Student's t-test, or the Mann-Whitney U test. Results: There were 130 patients with acute pancreatitis; recurrent pancreatitis was diagnosed in 23.8% of the cases. The most frequent causes were anatomical (29.6%), pharmacological (19.2%), and biliary (14.6%), although in 29.2% etiology was not identified. Fasting lasted 3.5 ± 3.8 days and parenteral nutrition was indicated in 26.9% of the cases for 10.8 ± 11.3 days. A statistical association with anatomical (p = 0.02) and pharmacological causes (p = 0.01) was found in the recurrent pancreatitis group; no other differences between acute pancreatitis and recurrent pancreatitis groups were observed. The mortality rate was 3.1%, it was not attributable to acute pancreatitis in any cases. Conclusion: Acute pancreatitis is associated with a high frequency of acute recurrent pancreatitis. Severity and complications did not show statistically significant differences in this investigation. Anatomical etiologies were the most relevant cause in this cohort. Fasting time and parenteral nutrition use were relevant. Genetics testing is required in this population.


RESUMO Objetivo: Descrever a epidemiologia e as características clínicas da pancreatite aguda e da pancreatite aguda recorrente em crianças. Métodos: Estudo observacional e retrospectivo com um componente analítico. Os pacientes foram classificados em dois grupos: pancreatite aguda e pancreatite recorrente. A relação com cada parâmetro obtido foi analisada com o teste de qui-quadrado, teste t de Student ou teste U de Mann-Whitney. Resultados: Foram analisados 130 pacientes com pancreatite aguda; pancreatite recorrente foi diagnosticada em 23,8% dos casos. As causas mais frequentes foram anatômicas (29,6%), farmacológicas (19,2%) e biliares (14,6%), embora em 29,2% a etiologia não tenha sido identificada. O jejum durou 3,5 ± 3,8 dias e a nutrição parenteral foi indicada em 26,9% dos casos por 10,8 ± 11,3 dias. Uma associação estatística com causas anatômicas (p = 0,02) e farmacológicas (p = 0,01) foi encontrada no grupo com pancreatite recorrente; não foram observadas outras diferenças entre os grupos pancreatite aguda e pancreatite recorrente. A taxa de mortalidade foi de 3,1% e nenhum caso foi atribuível à pancreatite aguda. Conclusão: A pancreatite aguda está associada à alta frequência de pancreatite aguda recorrente. A gravidade e as complicações não apresentaram diferenças estatísticas nesta investigação. Etiologias anatômicas foram a causa mais relevante nesta coorte. O tempo de jejum e o uso de nutrição parenteral foram relevantes. Testes genéticos são necessários em nossas populações.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Pancreatitis/etiology , Pancreatitis/epidemiology , Pancreatitis/diagnosis , Pancreatitis/therapy , Recurrence , Comorbidity , Acute Disease , Cross-Sectional Studies , Retrospective Studies , Fasting , Parenteral Nutrition , Colombia/epidemiology
17.
CorSalud ; 11(3): 258-262, jul.-set. 2019. graf
Article in Spanish | LILACS | ID: biblio-1089745

ABSTRACT

RESUMEN El quilomediastino como complicación de la cirugía cardiovascular tiene una incidencia de menos del 0,5% y es extremadamente raro después de los procedimientos intrapericárdicos. El origen de esta complicación es una lesión directa en los vasos linfáticos del mediastino anterior, en el área del timo o el conducto torácico, en la unión de las venas yugular izquierda y subclavia, que obstruye el drenaje del conducto torácico. En principio se prefiere el tratamiento conservador con suspensión de la vía oral y la administración parenteral de una dieta baja en grasas y triglicéridos de cadena media. Si el drenaje persiste después de 2 semanas de tratamiento conservador, debe considerarse la ligadura quirúrgica del ductus torácico como tratamiento de esta complicación. Se presenta un caso de un hombre que presentó acumulación mediastínica de líquido quiloso, tras una reintervención por sangrado en el segundo día del postoperatorio de una revascularización miocárdica quirúrgica.


ABSTRACT Chylomediastinum as a complication of cardiovascular surgery has a reported incidence of lower than 0,5% and is extremely rare following intrapericardial procedures. The origin of this complication is a direct injury to the anterior mediastinum lymphatics in the thymus area or the thoracic duct, at the junction of the left jugular and subclavian veins, obstructing thoracic duct drainage. Firstly, conservative treatment with low fat and medium chain triglyceride diet is prefered by cutting oral feding. If the drainage persists despite 2 weeks of conservative treatment, the surgical ligation of the ductus thoracicus may be considered for the management of this complication. We present the mediastinal chylous fluid accumulation in a male patient who underwent revision due to bleeding on postoperative second day after coronary artery bypass surgery.


Subject(s)
Myocardial Revascularization , Thoracic Surgery , Parenteral Nutrition
18.
Rev. Bras. Saúde Mater. Infant. (Online) ; 19(3): 701-710, Jul.-Sept. 2019. tab
Article in English | LILACS | ID: biblio-1041092

ABSTRACT

Abstract Objectives: To analyze the association between low birth weight (LBW) and the occurrence of the delay on the eruption of deciduous teething (DEDT) in children from 04 to 30 months, living in Salvador, Bahia. Methods: A cross-sectional study involved 520 children at four to thirty months of age, from public, private and philanthropic daycares from two districts in Salvador. A descriptive analysis and unconditional logistic regression were done to estimate the odds ratios (ORs), using the Confidence Interval of 95% as a criterion for accepting associations. Poisson regression was used as an analytical strategy to obtain the prevalence ratio. Results: the prevalence of the delay on the eruption was 10.29%. There was a positive association between LBW and occurrence of DEDT among children with less than 24 months, both in the unadjusted model (PR=2.07, 95%CI= 0.96 4.44) as in the adjusted (adjusted PR=2, 27, 95%CI= 1.02 5.07). Conclusions: the variables of development and nutritional at birth and during the early life may be important predictors of the chronology of eruption. Further investigations should be carried out towards the adequate evaluation of the LBW role in the occurrence of the delay on the eruption.


Resumo Objetivos: analisar a associação entre o Baixo Peso ao Nascer (BPN) e a ocorrência de atraso na erupção da dentição decídua (AED) em crianças de 04 a 30 meses, residentes em Salvador-BA. Métodos: estudo transversal envolvendo 520 crianças que frequentavam creches públicas, privadas e filantrópicas de dois Distritos Sanitários de Salvador-Ba. Procedeu-se a análise descritiva e regressão logística não-condicional para estimação da oddsratios (ORs), empregando-se o Intervalo de Confiança a 95% como critério para aceitar as associações. A regressão de Poisson foi utilizada como estratégia analítica para obtenção da Razão de Prevalência. Resultados: a prevalência de atraso na erupção foi de 10,29%. Verificou-se uma associa-ção positiva entre BPN e ocorrência de AED entre as crianças com menos de 24 meses no modelo bruto (RP=2,07, IC95%= 0,96 4,44) e ajustado (RP ajustada=2,27, IC95%= 1,02 5,07). Conclusões: variáveis de desenvolvimento e nutricionais ao nascimento e durante a vida precoce podem ser importantes preditores do tempo de erupção, sendo necessárias outras investigações para uma adequada avaliação desta associação.


Subject(s)
Infant , Child, Preschool , Tooth, Deciduous/growth & development , Tooth Eruption , Infant, Low Birth Weight , Odontogenesis/physiology , Brazil , Infant, Premature , Nutritional Status , Parenteral Nutrition , Calcium Deficiency , Fetal Growth Retardation
19.
Rev. Assoc. Med. Bras. (1992) ; 65(9): 1151-1155, Sept. 2019. tab, graf
Article in English | LILACS | ID: biblio-1041071

ABSTRACT

SUMMARY This report describes the post-bariatric-surgery evolution of an obese patient who had low adherence to the diet and micronutrient supplementation. Four years after two bariatric surgeries, the patient was admitted due to transient loss of consciousness, slow thinking, anasarca, severe hypoalbuminemia, in addition to vitamin and mineral deficiencies. She had subcutaneous foot abscess but did not present fever. Received antibiotics, vitamins A, D, B12, thiamine, calcium, and parenteral nutrition. After hospitalization (twenty-eight days), there was a significant body weight reduction probably due to the disappearance of clinical anasarca. Parenteral nutrition was suspended after twenty-five days, and the oral diet was kept fractional. After hospitalization (weekly outpatient care), there was a gradual laboratory data improvement, which was now close to the reference values. Such outcome shows the need for specialized care in preventing and treating nutritional complications after bariatric surgeries as well as clinical manifestations of infection in previously undernourished patients.


RESUMO Este relato descreve a evolução pós-cirurgia bariátrica de uma paciente obesa que apresentou baixa adesão à dieta e suplementação de micronutrientes. Quatro anos após duas cirurgias bariátricas, a paciente foi internada por perda transitória de consciência, raciocínio lento, anasarca, hipoalbuminemia grave, além de deficiências vitamínicas e minerais. Apresentava abscesso subcutâneo no pé, mas não apresentava febre. Recebeu antibióticos, vitaminas A, D, B12, tiamina, cálcio e nutrição parenteral. Após a internação (28 dias) houve redução significativa do peso corporal, provavelmente devido ao desaparecimento clínico da anasarca. A nutrição parenteral foi suspensa após 25 dias e a dieta oral foi mantida fracionada. Após a internação (atendimento ambulatorial semanal) houve uma melhora gradativa dos dados laboratoriais, que estavam próximos dos valores de referência. Tal desfecho mostra a necessidade de cuidados especializados na prevenção e tratamento de complicações nutricionais após cirurgias bariátricas, bem como manifestações clínicas de infecção em pacientes previamente desnutridos.


Subject(s)
Humans , Female , Adult , Streptococcal Infections/complications , Protein-Energy Malnutrition/complications , Bariatric Surgery/adverse effects , Postoperative Complications , Avitaminosis/complications , Avitaminosis/therapy , Parenteral Nutrition , Severe Acute Malnutrition/complications , Severe Acute Malnutrition/etiology , Severe Acute Malnutrition/therapy , Treatment Adherence and Compliance
20.
Yonsei Medical Journal ; : 484-486, 2019.
Article in English | WPRIM | ID: wpr-742555

ABSTRACT

Infantile cortical hyperostosis, or Caffey's disease, usually presents with typical radiological features of soft tissue swelling and cortical thickening of the underlying bone. The disease can be fatal when it presents antenatally, especially before a gestational age of 35 weeks. This fatal, premature form of the disease is known to occur in various ethnic groups around the globe, and approximately 30 cases have been reported in English literature. This paper is unique in that it is the first paper to report a lethal form of prenatal-type infantile cortical hyperostosis diagnosed in South Korea. Born at gestational age of 27 weeks and 4 days, the patient had typical features of polyhydramnios, anasarca, hyperostosis of multiple bones, micrognathia, pulmonary hypoplasia, and hepatomegaly. The patient was hypotonic, and due to pulmonary hypoplasia and persistent pulmonary hypertension, had to be supported with high frequency ventilation throughout the entire hospital course. Due to the disease entity itself, as well as prolonged parenteral nutrition, liver failure progressed, and the patient expired on day 38 when uncontrolled septic shock was superimposed. The chromosome karyotype of the patient was normal, 46, XX, and COL1A1 gene mutation was not detected.


Subject(s)
Edema , Ethnic Groups , Gestational Age , Hepatomegaly , High-Frequency Ventilation , Humans , Hyperostosis , Hyperostosis, Cortical, Congenital , Hypertension, Pulmonary , Infant, Newborn , Infant, Premature , Karyotype , Korea , Liver Failure , Micrognathism , Parenteral Nutrition , Polyhydramnios , Shock, Septic
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