RESUMEN
Teeth erupting at birth are referred to as natal teeth. It is a common and benign finding in the neonatal period. However, they may be associated with genetic syndromes like Ellis Van Creveld syndrome and Hallermann-Streiff syndrome. We report here a case of natal teeth in an infant with congenital hypothyroidism.
Asunto(s)
Hipotiroidismo Congénito/complicaciones , Hipotiroidismo Congénito/diagnóstico , Hipotiroidismo Congénito/terapia , Epífisis , Humanos , Lactante , Recién Nacido , Masculino , Mandíbula , Dientes Neonatales , Tamizaje Neonatal , TibiaAsunto(s)
Estatura , Preescolar , Creatinina/sangre , Diagnóstico Diferencial , Diagnóstico Precoz , Trastornos del Crecimiento/diagnóstico , Trastornos del Crecimiento/etiología , Humanos , Hipertensión/etiología , Fallo Renal Crónico/complicaciones , Fallo Renal Crónico/terapia , Pruebas de Función Renal , Palidez/diagnóstico , Palidez/etiología , Diálisis Renal/métodos , Insuficiencia Respiratoria/diagnóstico , Insuficiencia Respiratoria/etiología , Medición de RiesgoRESUMEN
Objective. To identify risk factors associated with Persistent diarrhea (PD) and deaths due to PD. Methods. This prospective case control study included 60 children with PD (cases) and 60 children (controls) with acute diarrhoea (AD). Detailed history, examination and appropriate investigations were done for all children. Crude Odds ratio was calculated for each risk factor by univariate analysis and adjusted odds ratio was calculated by multivariate logistic regression. Results. Prior antibiotic use, steroid use, anemia, vitamin A deficiency, malnutrition, LRI, UTI, oral candidiasis, and hyponatremia, were statistically significant risk factors by univariate analysis. Prior antibiotic use, vitamin A deficiency, malnutrition and LRI were independently associated with PD by multivariate logistic regression analysis. The risk factors for mortality were stool frequency more than 10 times per day, severe malnutrition, oral candidiasis, hypoalbuminemia and HIV positivity. Conclusions. The presence of these risk factors should alert the clinician to take appropriate measures, to decrease the mortality.
Asunto(s)
Anemia/complicaciones , Antibacterianos/uso terapéutico , Estudios de Casos y Controles , Niño , Preescolar , Enfermedad Crónica , Diarrea/tratamiento farmacológico , Diarrea/etiología , Diarrea/mortalidad , Femenino , Humanos , Hiponatremia , Lactante , Modelos Logísticos , Masculino , Desnutrición/etiología , Análisis Multivariante , Oportunidad Relativa , Estudios Prospectivos , Infecciones del Sistema Respiratorio , Factores de Riesgo , Deficiencia de Vitamina A/complicacionesRESUMEN
Hyperinsulinemic hypoglycemia is the most common cause of persistent hypoglycemia in infancy. While most of the cases are sporadic more than 100 mutations have been reported in the familial type. The authors report a case of familial hyperinsulinemic hypoglycemia with homozygous T294M mutation of the KCNJ11 gene, which responded to diazoxide therapy.
Asunto(s)
Antihipertensivos/uso terapéutico , Hiperinsulinismo Congénito/tratamiento farmacológico , Hiperinsulinismo Congénito/genética , Diazóxido/uso terapéutico , Femenino , Homocigoto , Humanos , India , Recién Nacido , Mutación , Canales de Potasio de Rectificación Interna/genéticaRESUMEN
OBJECTIVE: To study if different forms of clinical presentation of tuberculosis in children are associated with a different type of tuberculin reaction. METHODS: This cross sectional study, describing Tuberculin skin testing (TST) responses in 268 children (134 cases and 134 controls) less than 12 yr of age was carried out over a period of 18 months at JIPMER, a tertiary care referral hospital in Pondicherry, India. The qualitative and quantitative TST responses in various clinical forms of Tuberculosis were analysed. RESULTS: Koch's and Listeria variants were more common in children with TB Lymphadenitis and Pulmonary TB respectively. 10% of the study children with TB meningitis were tuberculin negative. CONCLUSION: Qualitative TST responses are non-homogeneous among the various clinical types of childhood tuberculosis. They are not a correlate of protective immunity with little or no prognostic significance.
Asunto(s)
Vacuna BCG , Niño , Preescolar , Humanos , Lactante , Prueba de Tuberculina , Tuberculosis/diagnósticoRESUMEN
We report acute onset quadriplegia in a ten year old boy associated with basal ganglia lesions due to biotin deficiency. Prolonged raw egg consumption was identified as predisposing factor for biotin deficiency. Treatment with biotin resulted in remarkable recovery.
Asunto(s)
Enfermedades de los Ganglios Basales/diagnóstico , Biotina/deficiencia , Niño , Huevos/efectos adversos , Humanos , Imagen por Resonancia Magnética , Masculino , Cuadriplejía/tratamiento farmacológico , Deficiencia de Vitamina B/diagnósticoRESUMEN
The study was conducted to identify the problems related to feeding of children post tsunami in four villages in Pondicherry. Data were collected from 100 randomly chosen families who had an infant or a young child below 3 years of age during Tsunami. Informants were the mothers. In the population studied, 30% mothers did not exclusively breast feed for 6 months; 58% bottle fed their children and 51% fed their infants with commercial formula. The occurrence of diarrhea was three times higher among children who were fed with free breast milk substitutes (BMS) than in those who were not fed with the same. Those populations, wherein a pre-existing tradition of artificial feeding is present, infants are at further risk during a crisis situation like Tsunami. Breast feeding practices need strengthening even in routine conditions to tackle a disaster rather than intervention after the disaster.