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China Journal of Chinese Materia Medica ; (24): 984-988, 2004.
Artículo en Chino | WPRIM | ID: wpr-293655

RESUMEN

<p><b>OBJECTIVE</b>To study the predominant calcium-antagonist components of Danshen injection.</p><p><b>METHOD</b>The effects of danshensu, protocatechualdehyde and Danshen injection on calcium concentration in cytoplasm of erythrocytes were examined in vitro by the fluorescent Ca+ -chelator fura-2.</p><p><b>RESULT</b>Either DS182 or PCAD can decrease in dose-dependent cytosolic free calcium concentration in human erythrocytes. They had additive effect when mixed, which was similar to Danshen injection.</p><p><b>CONCLUSION</b>DS182 and PCAD may be predominant calcium-antagonist components of Danshen injection.</p>


Asunto(s)
Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Benzaldehídos , Farmacología , Calcio , Metabolismo , Catecoles , Farmacología , Citoplasma , Metabolismo , Sinergismo Farmacológico , Medicamentos Herbarios Chinos , Farmacología , Eritrocitos , Metabolismo , Inyecciones , Lactatos , Farmacología , Plantas Medicinales , Química , Salvia miltiorrhiza , Química
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