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Rev. Soc. Bras. Med. Trop ; 47(2): 254-256, Mar-Apr/2014. graf
Artículo en Inglés | LILACS | ID: lil-710359

RESUMEN

Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.


Asunto(s)
Adulto , Femenino , Humanos , Antifúngicos/uso terapéutico , Fluconazol/uso terapéutico , Meningitis Criptocócica/tratamiento farmacológico , Infección Puerperal/tratamiento farmacológico , Imagen por Resonancia Magnética , Meningitis Criptocócica/diagnóstico , Infección Puerperal/diagnóstico
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