Some distribution features of the hematopoietic and immunological cells in the bone marrow in 38 Vietnamse healthy people

38 Vietnamese adult healthy people studied on peripheral blood and bone marrow material to investigate on hemopoiesis and distribution of blood cells as well as lymphocytic subsets. The results showed that in peripheral blood, the hematologic and lymphocytic count parameters are sames as medical literature. In bone marrow material, nucleated cell count is in strict range with mean value of 54+/- 16G/L. The three common lines of bone marrow are granulocytic, erythrocytic and lymphocytic lines are distributed in distribution of lymphocytic subsets in bone marrow in comparison to peripheral blood. All subsets are more higher than that of peripheral bood about 2.5 to 4 time times with conversely ratio CD4/8.

Immunological disorder in patients with acquired bone marrow failure with unknown causes

The study was carried out in 65 aplastic anemia patients admitted into B¹ch Mai hospital during the period 1995-1999 on the issues of immunological characteristics. The results can be summarized as follows: The count of lymphocytes and the majority of sub-groups of lymphocytes were decreased compared with the control group (p<0.05 - 0.01). The TCD4/TCD8 ratio is decrease compared with the control group. The level of IgG in plasma increased. In the bone marrow, the count of subgroup of lymphocytes decreased compared with the control group. Comparing between peripheral blood and bone marrow, it can be seen that the percentage of T lymphocytes and its sub-groups decreased significantly. The change of the percentage of B lymphocytes however, it is not significant.