Comparative study on chemical composition and antimicrobial activity of Egyptian and Canadian propolis

Two propolis samples from Egypt and Canada were investigated by GC/MS, 103 compounds were identified. mainly terpenoids and phenolics. 17 being new for propolis. The samples showed some similarities in their qualitative composition of the phenolics. In Canadian propolis benzoic acid, trans-p-coumaric acid, benzyl-trans-4-coumarate and pinocembrin were predominant. The Egyptian propolis showed the presence of 7 di-and triterpenoids. from which three are new. The antimicrobial activity of propolis collected from Egyptian propolis showed the highest antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi, .Asprgillus flavus; Asprgillus fumigatus; Mucor and Candida albicans, while Canadian propolis has the highest activity against Staphylococcus aureus: Bacillus subtitlis; Erwinia carotovora; Asprgillus ochraceus and Asprgillus niger

new triterpenoid from glycyrrhiza glabra L. and antimicrobial activity

A new pentacyclic triterpenoid was isolated from the minor constituents of local liquorice roots. The structure was determined by means of [1]H-H COSY, [13]C APT, HMQC, HMBC experiments and MS spectroscopy. Another triterpenoid was isolated in a very small amount and its structure was assumed from [1]H-NMR and MS only. The antimicrobial activity of the pentacyclic triterpenoids against Staphylococcus aureus; Escherichia coli, and Candida albicans were investigated. Compound 1 had the highest antibacterial activity against Escherichia coli: and Staphylococcus aureus, while compound 2 had the highest antifungal activity against Candida albicans

Antiviral activity and chemical composition of European and Egyptian propolis

Four propolis samples from Austria, Egypt, France and Germany were investigated by GC/MS, where twenty compounds were being new for propolis. The samples showed some similarities in their qualitative composition. phenylethyl-trans-caffeate, benzyl ferulate and galangin were predominant in German propolis. Benzyl caffeate was predominant in French sample. pinocembrin was predominant in French and Austrian propolis and trans-p-coumaric acid was predominant in all samples. Egyptian propolis is characterized by the presence of unusual esters of caffeic acid with C[12]- C[16] fatty alcohols, mainly saturated. The antiviral activity of propolis samples from Austria, Egypt, France and Germany against avian reo virus [ARV] and infectious bursal disease virus [IBDV] was evaluated. All propolis samples reduced the viral infectivity in varied degree according to the propolis origin. Egyptian propolis showed the highest antiviral activity against avian reo virus and infectious bursal disease virus

Chemical composition and antimicrobial activity of Sidr honey

A comparison between two methods of extraction of Sidr honey was performed to elucidate the difference in chemical composition and antimicrobial activity. The results of the GC/MS studies of the n-hexane extracts by methods A [extraction without dilution] and B [extraction after dilution with water] for Sidr honey showed that method A contains all terpenoids and method B contains higher significant concentration of fatty acids. Some compounds were identified for the first time in Sidr honey. Piperitone, calamanene -1S-trans, 4-methoxy -butanoic acid, 2- pentanol -5- methoxy-2- methyl, Pyrido [3,2-d] pyrimidine - 4-ol, 2- ethyl- 5- tridecylpyrrolidine, quinoline -, 5,6,7,8-tetrahydro - 3-methyl and quinoline - 4,8-dimethyl. The antimicrobial activity varied according to the type of pathogen. However the method A showed the highest antibacterial activity, the method B had the highest antifungal activity

Influence of Egyptian propolis as antifungal agent

The antifungal activity of Egyptian propolis against 9 genera of fungi was determined. These genera are belonging to Cladosporium, Mucor, Scopulariopsis, Penicillium, Rhizopus, Fusarium, Aspergillus, Alternaria and Rhodoterola. The results revealed that Egyptian propolis induced inhibition of fungal growth. This inhibition varied according to the type of fungi. The minimal inhibitory concentration of propolis ranged from 1.20 - 3.60 mg /ml. It was obvious that the minimum inhibitory concentration was 3.60 mg / ml tot Alternaria and Fusarium whereas the concentration [1.20 mg / ml] was recorded for Aspergillus and Penicillium