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1.
Al-Azhar Journal of Dental Science. 2004; 7 (2): 123-131
en Inglés | IMEMR | ID: emr-144634

RESUMEN

Prepubertal peripdontitis is a rapidly prognessive form of early onset periodontitis leading to destruction of the periodontal support of the primary and secondary dentition. The aim of this study is to determine the basics for genetic mapping of six Egyptian cases suffering from prepubertal periodontitis and its variants. After completion of clinical assessment, cytogenetic study was performed for all cases including chromosomal analysis and plain X-ray for their hands. The gentic study revealed arachnodactyly of their hands, However no radiographic deformity of their fingers was detected. The cytogenetic study for all patients did not show any abnormality. This study might have important implications on oral public health, and in diagnosis and treatment of periodontitis


Asunto(s)
Humanos , Periodontitis Agresiva/genética , Análisis Citogenético , Aberraciones Cromosómicas , Queratodermia Palmoplantar , Índice de Placa Dental , Índice Periodontal , Radiografía Panorámica
2.
Al-Azhar Journal of Dental Science. 2002; 5 (1): 41-51
en Inglés | IMEMR | ID: emr-122825

RESUMEN

38 oral biopsy specimens of hyperplastic surface epithelial lesions [8 cases], epithelial dysplastic lesions [12 cases] and squamous cell carcinoma [SCC] [18 cases] as well as six biopsies of normal oral mucosa were processed for immunohistochemical staining with anti VCAM-1 to identify vascular and non vascular expression of VCAM-1 in the hyperplastic and dysplastic oral lesions as well as oral SCC compared to normal oral mucosa and to examine if it has an active role in the pathogenesis of these lesions that could point the way to the developing of new therapeutic stratigies. The results of this study suggested that VCAM-1 expression has essentially a direct relation with the density and distribution of chronic inflammatory cell infiltration. VCAM-1 is not related to the different grades of epithelial dysplasia and tumor cell differentiation. It cann't be also used as an indicator of tumor angiogenesis


Asunto(s)
Carcinoma de Células Escamosas/inmunología , Hiperplasia/inmunología , Molécula 1 de Adhesión Celular Vascular , Neovascularización Patológica , Biopsia
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